Human resources play a very important role because humans are the cogs of all company activities. Efforts to improve performance are carried out through a well-organized leadership system and motivating to increase employee morale. This study aims to determine the effect of transformational leadership, work motivation, and organizational commitment on employee performance. This study uses a survey method with a questionnaire as a data collection tool. The population in this study were all medical and paramedical personnel at the Public health center in Surabaya, Indonesia, totaling 60 people. Samples were taken as many as 60 employees with the sampling technique of Non-Probability Sampling with Saturated Sampling, where all members of the population became the sample. The data obtained through the questionnaire were then tested for validity and reliability using the product-moment correlation formula and Cronbach's alpha. Data analysis used multiple regression analysis, F test, t-test, and coefficient of determination test and was accompanied by classical assumption testing. The results showed that: (1) Individual/partial transformational leadership did not affect the performance of medical and paramedical officers at Public health center in Surabaya, Indonesia. This is evident from the results of the t-test to obtain a t-value of 1.028 with a t-table of 2.05 with a significance level of 5%. This means that transformational leadership that is carried out partially without being followed by work motivation and organizational commitment will not affect employee performance. (2) Work motivation has a positive effect on the performance of medical officers and paramedics at the Public health center in Surabaya, Indonesia. This is evident from the results of the t-test to obtain a t-value of 34.013 with a t-table of 2.05 with a significance level of 5%, then H2 is accepted. This means that the higher the employee's work motivation, the performance will increase. (3) Organizational Commitment has a positive effect on the performance of medical officers and paramedics at the Public Health Center. This is evident from the results of the t-test to obtain a t-value of 3.478 with a t-table of 2.05 with a significance level of 5%, then H3 is accepted. This means that the higher the organizational commitment of employees, the performance will increase. 05 with a significance level of 5%, then H2 is accepted. This means that the higher the employee's work motivation, the performance will increase. (3) Organizational Commitment has a positive effect on the performance of medical officers and paramedics at the s. This is evident from the results of the t-test to obtain a t-value of 3.478 with a t-table of 2.05 with a significance level of 5%, then H3 is accepted. This means that the higher the organizational commitment of employees, the performance will increase. 05 with a significance level of 5%, then H2 is accepted. This means that the higher the employee's work motivation, the performance will increase. (3) Organizational Commitment has a positive effect on the performance of medical officers and paramedics at the Public health center in Surabaya, Indonesia. This is evident from the results of the t-test to obtain a t-value of 3.478 with a t-table of 2.05 with a significance level of 5%, then H3 is accepted. This means that the higher the organizational commitment of employees, the performance will increase. then H3 is accepted. This means that the higher the organizational commitment of employees, the performance will increase. then H3 is accepted. This means that the higher the organizational commitment of employees, the performance will increase.