Mineral fillers play a critical role in the performance of asphalt mixes. Several types of mineral fillers are used worldwide. In Kuwait, two main mineral fillers are used; ordinary Portland cement (OPC) and pulverized limestone. This paper presents the results of a study undertaken to compare the effects of using the two types of mineral fillers on the strength of asphalt mixes as measured by Marshall stability and retained strength. Three filler contents were considered in the study; they were: 4, 5, and 6% by weight of aggregate. The analysis showed that both filler types have similar effect on Marshall stability. However, using OPC resulted in higher values of retained strength.