Left ventricular dyssynergy, or localized abnormal contraction in the form of absent movement (akinesis) or paradoxical movement (dyskinesis) may result from regional myocardial ischemia or from myocardial infarction and scar formation in patients with coronary artery disease. Dyssynergy can cause heart failure even without an aneurysmal bulge of the left ventricle and even though the uninvolved myocardium contracts normally. Important features regarding the heart failure are the size of the area of dyssynergy, the work load imposed on the ventricle, the functional state of the remaining portion of the ventricle, and the ability of ventricle to compensate for the abnormality by appropriate dilatation and hypertrophy. Left ventricular angiocardiography with selective coronary angiography is most useful in diagnosing the presence and severity of dyssynergy and of the other postinfarction abnormalities which may coexist. Patients who have chronic, severe, refractory heart failure associated with cardiac dilatation and a demonstrable zone of akinesis or dyskinesis should be considered for surgical resection of the involved portion of left ventricular wall.