In response to frequent wind damage accidents in roof cladding, a performance-based wind engineering framework for roof cladding is proposed, taking the roof plate unit as the research object. In the uncertain analysis part, extreme wind pressures in each zone of the roof are evaluated using the independent storm method. In the vulnerability analysis part, a large number of numerical simulations are carried out based on Latin hypercube sampling to obtain the probability vulnerability curves of various types of roof plate units through regression fitting. In the loss analysis part, a total life cycle cost model of the roof cladding is established considering initial cost and wind disaster losses. In the performance target part, wind load levels and performance levels are divided based on the extreme wind pressure in each zone of roof under various return periods and the wind uplift failure process of roof plates respectively. Combined with wind load levels and performance levels, performance targets that can be selected by owners are proposed. The application of performance-based wind engineering is introduced using a flat roof as an example, which shows that the probability of reaching insignificant, moderate damage, and moderate damage under recurrence periods of 10, 50, and 100 years for a certain type of roof plate unit is 89 %, 91 %, and 72 %, respectively, which meets the owner's performance objectives and can be applied to guide the wind-resistant design of the cladding of the flat roof. Compared with the complexity of existing performance-based wind engineering, the performance-based wind engineering proposed in this manuscript can coordinate with the traditional wind-resistant design method of roof cladding, and can ensure the economy of design results.