Introduction and Objective Cardiac pacemakers and Implantable Cardioverter-Defibrillators (ICD) are devices used to treat a range of cardiac dysrhythmias. Symptomatic cardiac perforation may occur in as many as 4.2% of pacemaker or ICD placements with 1.2% of pacemaker or ICD placements leading to clinically significant pericardial effusion. Acute onset of symptoms within 24 hours of device placement due to cardiac perforation is particularly rare, with a paucity of reported cases. This report describes a case of bedside Emergency Department (ED) ultrasound identifying an acute onset of pericardial effusion following cardiac pacemaker placement in an 85-year-old woman who experienced pleuritic and oscillating chest pain. Case Presentation An 85-year-old woman with a past medical history of hypertension, diabetes and dual-chamber pacemaker placement two days ago presented to the ED with pleuritic and oscillating chest pain. Initial bedside Point of Care Ultrasound (POCUS) exam, performed by the emergency department attending, revealed a moderate pericardial effusion with evidence of a pacemaker lead perforation through the right ventricular myocardium. Lead perforation and effusion were confirmed via formal transthoracic echocardiogram. Minutes later, the patient was treated with a right ventricle lead repositioning procedure and recovered uneventfully. Conclusion Symptomatic cardiac perforation due to pacemaker or ICD placement is rare, with a range of potential complications which typically occur weeks to months after placement. This case demonstrates the utility of POCUS exam for patients presenting to the ED for non-specific chest pain as it facilitated the timely diagnosis of an atypical presentation of ICD-induced wall perforation.