Perceptual Responses Research Articles

How interior design responds to neurodiversity: implementing wearable technologies in neurodesign processes

This perspective article, looking through the lens of neurodiversity, discusses the benefits and challenges of implementing virtual environments and wearable technologies in interior design and related fields. While the relationship between human perception and built environments has long been studied in the environmental design disciplines, the direct impact on occupant performance related to neurodiversity has been underexplored in research, with a shortage of knowledge supporting how it can be applied in design practice concerning the end users. Individuals’ perceptual, cognitive, and affective responses to their surroundings vary, as neurodiversity plays a key role in the invisible, human-environment interaction. Thus, measuring, analyzing, and understanding affective, perceptual, and cognitive experiences is a challenging process in which various factors come into play, and no single method or measurement can adequately work for all. Due to such challenges, research has also utilized various biometric measurements and tools for immersive experiments in physical and virtual environments, e.g., eye tracking used in studies on gaze behaviors and immersive virtual reality (IVR) used in studies on the spatial perception of dementia patients. Along with empirical methods, studies have stressed the contribution of phenomenology to looking into the hidden dimension, the ‘why factors’ of perception, cognition, and affectivity. Concerning the methodological approach, this perspective article shares insights into a novel process model, Participatory Neurodesign (PND) framework, used in wayfinding research and design processes utilizing eye tracking and IVR. Opportunities for neurodesign research and design practice are also discussed, focusing on the health, safety, and wellbeing of end-users.

Sustainability and perceptual responses during handgrip holds to failure at two fatigue thresholds.

Critical force (CF) provides an estimate of the asymptote of the force-duration curve and the physical working capacity at the rating of perceived exertion (PWCRPE) estimates the highest force that can be sustained without an increase in perceived exertion. Handgrip-related musculoskeletal disorders and injuries derived from sustained or repetitive motion-induced muscle fatigue are prevalent in the industrial workforce. Thus, it is important to understand the physiological mechanisms underlying performance during handgrip specific tasks to describe individual work capacities. This study examined prolonged, isometric, handgrip exercises by comparing the relative force levels, sustainability, and perceptual responses at two fatigue thresholds, CF and PWCRPE. Ten women (26.5 ± 3.5years) performed submaximal, isometric handgrip holds to failure (HTF) with the dominant hand at four, randomly ordered percentages (30, 40, 50, and 60%) of maximal voluntary isometric contraction (MVIC) force to determine CF and PWCRPE. Isometric handgrip HTF were performed at CF and PWCRPE. Time to task failure and RPE responses were recorded. There were no differences in the relative forces (p = 0.381) or sustainability (p = 0.390) between CF (18.9 ± 2.5% MVIC; 10.1 ± 2.7min) and PWCRPE (19.5 ± 7.9% MVIC; 11.6 ± 8.4min), and the RPE increased throughout both holds at CF and PWCRPE. It is possible that complex physio-psychological factors may have contributed to the fatigue-induced task failure. CF and PWCRPE may overestimate the highest force output that can be maintained for an extended period of time without fatigue or perceptions of fatigue for isometric handgrip holds.

Linking paranormal and conspiracy beliefs to illusory pattern perception through signal detection theory

Previous research indicates that irrational beliefs (Paranormal beliefs & conspiracy theory endorsement) are associated with the perception of patterns in noise, but the previous findings do not conclusively describe this relationship. This study aims to disentangle the underlying parameters of this association by applying a signal detection theory approach, thus allowing to distinguish illusory pattern perception (false alarms) from perceptual sensitivity and response tendencies—while also taking base rate information into account. Results from a large sample (N = 723) indicate that paranormal beliefs relate to a more liberal response bias and a lower perceptual sensitivity, and that this relationship is driven by illusory pattern perception. Such a clear pattern could not be observed for conspiracy beliefs, for which the increase in false alarm rates was moderated by the base rate. The associations between irrational beliefs and illusory pattern perception were however less substantial compared to other sources of variance. Implications are discussed.

Short vs. Long Bouts of All-Out Rope Skipping: Effects on Metabolic and Perceptual Responses

Rope skipping has been well documented for eliciting positive effects on various health outcomes and contributing to overall physical activity levels. However, the specific health benefits may depend on the duration and intensity of the exercise bouts. This study aimed to compare the (1) metabolic and (2) perceptual responses between short (30 s) and long (3 min) bouts of all-out rope skipping, and to (3) evaluate the reliability and validity of a newly invented electronic rope (E-rope). A total of 23 young adults (13 males and 10 females; aged 23.23 ± 2.62 y) repeated short and long skipping bouts on two testing days. The oxygen consumption (V·O2), peak respiratory exchange ratio (RER), heart rate (HR), rate of perceived exertion (RPE), and post-exercise muscle soreness were assessed during each trial. Longer skipping bouts (148.33 skips·min−1) resulted in significantly greater metabolic responses (p < 0.01, d = 1.00–3.27), higher rates of perceived exertion (p < 0.01, d = 2.28), and more post-exercise muscle soreness (p < 0.01, d = 0.66–1.49) compared to shorter bouts (165.83 skips·min−1). The E-rope demonstrated sufficient concurrent validity (r > 0.9) and between-day reliability (ICC3,1 = 0.89–0.95) but slightly overestimated the number of skips. Both long and short all-out skipping bouts were considered moderate-to-vigorous exercise, but longer bouts resulted in higher metabolic and perceptual demands. These findings may be useful for practitioners to strategically apply different skipping bouts to improve physical activity levels and facilitate training adaptation. The E-rope could serve as a self-monitoring and self-evaluating tool.

Parieto-occipital ERP indicators of gut mechanosensation in humans

Understanding the neural processes governing the human gut-brain connection has been challenging due to the inaccessibility of the body’s interior. Here, we investigated neural responses to gastrointestinal sensation using a minimally invasive mechanosensory probe by quantifying brain, stomach, and perceptual responses following the ingestion of a vibrating capsule. Participants successfully perceived capsule stimulation under two vibration conditions (normal and enhanced), as evidenced by above chance accuracy scores. Perceptual accuracy improved significantly during the enhanced relative to normal stimulation, which was associated with faster stimulation detection and reduced reaction time variability. Capsule stimulation induced late neural responses in parieto-occipital electrodes near the midline. Moreover, these ‘gastric evoked potentials’ showed intensity-dependent increases in amplitude and were significantly correlated with perceptual accuracy. Our results replicated in a separate experiment, and abdominal X-ray imaging localized most capsule stimulations to the gastroduodenal segments. Combined with our prior observation that a Bayesian model is capable of estimating computational parameters of gut-brain mechanosensation, these findings highlight a unique form of enterically-focused sensory monitoring within the human brain, with implications for understanding gut feelings and gut-brain interactions in healthy and clinical populations.

Self-selected or fixed: is there an optimal rest interval for controlling intensity in high-intensity interval resistance training?

This study investigated the effects of different rest interval strategies during high-intensity interval resistance training (HIRT) on cardiorespiratory, perceptual, and enjoyment responses among trained young men. Sixteen men experienced with HIRT underwent cardiopulmonary exercise testing and were familiarized with the exercises and HIRT protocol. On the subsequent three visits, interspaced 48-72h, participants performed HIRT sessions with different rest intervals in a randomized order: 10s and 30s fixed rest intervals (FRI-10 and FRI-30), and self-selected rest interval (SSRI). Oxygen uptake (VO2), heart rate (HR), and recovery perception (Total Quality Recovery Scale) were measured during HIRT, while enjoyment responses (Physical Activity Enjoyment Scale) were assessed immediately after the sessions. The VO2 during exercise was greater in FRI-10 than FRI-30 (55% VO2max and 47% VO2max, respectively, p = 0.01), while no difference occurred between SSRI and bouts performed with fixed intervals (52% VO2max vs. FRI, p > 0.05). HR, excess post-exercise oxygen consumption (EPOC), recovery perception, and enjoyment responses were similar across conditions (p > 0.05). Exercise intensity was not affected by the rest interval strategy. High exercise intensity was maintained in sessions performed with FRI or SSRI, without negative repercussions on the duration of training sessions and enjoyment responses after exercise sessions.

Intermittent blood flow occlusion modulates neuromuscular, perceptual, and cardiorespiratory determinants of exercise tolerance during cycling.

Constant blood flow occlusion (BFO) superimposed on aerobic exercise can impair muscle function and exercise tolerance; however, no study has investigated the effect of intermittent BFO on the associated responses. Fourteen participants (n = 7 females) were recruited to compare neuromuscular, perceptual, and cardiorespiratory responses to shorter (5:15s, occlusion-to-release) and longer (10:30s) BFO applied during cycling to task failure. In randomized order, participants cycled to task failure (task failure 1) at 70% of peak power output with (i) shorter BFO, (ii) longer BFO, and (iii) no BFO (Control). Upon task failure in the BFO conditions, BFO was removed, and participants continued cycling until a second task failure (task failure 2). Maximum voluntary isometric knee contractions (MVC) and femoral nerve stimuli were performed along with perceptual measures at baseline, task failure 1, and task failure 2. Cardiorespiratory measures were recorded continuously across the exercises. Task failure 1 was longer in Control than 5:15s and 10:30s (P < 0.001), with no differences between the BFO conditions. At task failure 1, 10:30s elicited a greater decline in twitch force compared to 5:15s and Control (P < 0.001). At task failure 2, twitch force remained lower in 10:30s than Control (P = 0.002). Low-frequency fatigue developed to a greater extent in 10:30s compared to Control and 5:15s (P < 0.047). Dyspnea and Fatigue were greater for Control than 5:15s and 10:30s at the end of task failure 1 (P < 0.002). Exercise tolerance during BFO is primarily dictated by the decline in muscle contractility and accelerated development of effort and pain.

Comparison of anaerobic speed reserve and maximal aerobic speed methods to prescribe short format high-intensity interval training.

The purpose of the study was to compare the degree of intersubject variability in the cardiorespiratory, metabolic, and perceptual responses to high-intensity interval training (HIIT) prescribed based on the relative anaerobic speed reserve (ASR) or maximal aerobic speed (MAS) and to identify the optimal % ASR for execution of such HIIT. Seventeen male physical education students (age: 23.6 ± 1.1 years, height: 180.2 ± 5.9, body mass: 78.3 ± 8.1 kg; % body fat: 14.3 ± 2.7%) volunteered to execute three randomly scheduled 10-min HIIT exercises at 110% vVO2max , Δ15% ASR, or Δ25% ASR. Analysis of variance for repeated measures and the least significant difference post-hoc test were used to compare the physiological responses and the mean of individual residuals between the training sessions. The coefficients of variation (CV) of time spent ≥90% of maximal oxygen uptake (VO2max ) and maximal heart rate (HRmax ), peak VO2 , mean VO2 , peak HR, mean HR, blood lactate [La], and rating of perceived exertion (RPE) were 48.7%, 35.9%, 9.3%, 7%, 3.5%, 4.8%, 32%, and 16.9% during 110% vVO2max , 47.2%, 31%, 7.5%, 6.7%, 3.9%, 4.6%, 24.2%, and 14.6% during Δ15% ASR, and 48.1%, 31.5%, 7.6%, 8.4%, 3.6%, 4.1%, 20.2%, and 3.4% during Δ25% ASR session, respectively. Only the residuals in RPE were significantly (p < 0.001) higher in 110% vVO2max and Δ15% ASR in comparison to Δ25% ASR. Time spent ≥90% HRmax /VO2max was maximized during Δ15% ASR session, albeit this was not significantly different from other sessions. The ASR-based method leads to reduced CVs of physiological and perceptual responses during 10-min HIIT; however, only reductions in [La] and RPE may be considered practically meaningful. Practitioners can use vVO2max for prescription of 10-min HIIT session comprised of 15-s work and passive recovery intervals.

Modeling enablers of agility of healthcare organizations

PurposeThis purpose of the study is to investigate enablers of building agility capabilities in healthcare organisations in developing countries. The key research questions are: (1) What are the key enablers for building healthcare agility? (2) Is there an interdependence among the enablers of healthcare agility? (3) What is the driving and dependence power of the enabling factors of healthcare agility?Design/methodology/approachThe enablers for building capabilities of organisational agility were identified from the extant literature. Perceptual responses for pair-wise comparison of identified enablers were collected from 17 clinical and non-clinical professionals working in Indian hospitals through online interviews. Participants were selected from India which supposedly represents the socioeconomic contexts and healthcare systems in developing economies. Next, the data was analysed using multicriteria decision-making (MCDM) techniques to develop a structural framework depicting the enablers and their interdependence.FindingsThe TISM framework showed that the two most influential enablers of healthcare agility in developing countries are policy and regulatory support and strategic commitment and resource availability. The results were based on the analysis of four enablers identified from the literature. The results of MICMAC analysis revealed the driving and dependence power of each enabler and classified the enablers into driving, autonomous, dependence and linkage groups.Practical implicationsThe study will help stakeholders and academics in the healthcare domain in devising effective strategies for building agility within healthcare systems and processes.Originality/valueThe study contributes to the service operations literature on building agile systems for dynamic and complex service environments.

Hypoxia Does Not Impair Resistance Exercise Performance or Amplify Post-Exercise Fatigue

ABSTRACT Purpose: To determine whether performing resistance exercise in hypoxia acutely reduces performance and increases markers of fatigue, and whether these responses are exaggerated if exercising at high versus low work rates (i.e., exercising to failure or volume matched non-failure). Methods: Following a within-subject design, 20 men completed two trials in hypoxia (13% oxygen) and two in normoxia (21% oxygen). The first session for hypoxic and normoxic conditions comprised six sets of bench press and shoulder press to failure (high work rate), while subsequent sessions involved the same volume distributed over 12 sets (low work rate). Physical performance (concentric velocity) and perceptual responses were measured during exercise and for 72 hr post-exercise. Neuromuscular performance (bench throw velocity) was assessed pre- and post-session. Results: Hypoxia did not affect physical performance, neuromuscular performance, and perceptual recovery when exercising at high or low work rates. Higher work rate exercise caused greater acute decrements in physical performance and post-exercise neuromuscular performance and increased perceived exertion and muscle soreness (p ≤ 0.006), irrespective of hypoxia. Conclusions: Hypoxia does not impact on resistance exercise performance or increase markers of physical and perceptual fatigue. Higher exercise work rates may impair physical performance, and exaggerate fatigue compared to low work rate exercise, irrespective of environmental condition. Practitioners can prescribe hypoxic resistance exercise without compromising physical performance or inducing greater levels of fatigue. For athletes who are required to train with high frequency, decreasing exercise work rate may reduce post-exercise markers of fatigue for the same training volume.

Altitude-induced effects on neuromuscular, metabolic and perceptual responses before, during and after a high-intensity resistance training session.

We tested if an acute ascending to 2320m above sea level (asl) affects corticospinal excitability (CSE) and intracortical inhibition (SICI) measured with transcranial magnetic stimulation (TMS) at rest, before, during and after a traditional hypertrophy-oriented resistance training (RT) session. We also explored whether blood lactate concentration (BLa), ratings of perceived exertion (RPE), perceived muscular pain and total training volume differed when the RT session was performed at hypoxia (H) or normoxia (N). Twelve resistance-trained men performed eight sets of 10 repetitions at 70% of one repetition maximum of a bar biceps curl at N (SpO2 = 98.0 ± 0.9%) and H (at 2320 asl, SpO2 = 94.0 ± 1.9%) in random order. Before each session, a subjective well-being questionnaire, the resting motor threshold (rMT) and a single pulse recruitment curve were measured. Before, during and after the RT session, BLa, RPE, muscle pain, CSE and SICI were measured. Before the RT session only the rMT differed between H (- 5.3%) and N (ES = 0.38). RPE, muscle pain and BLa increased through the RT session and were greater at H than N (12%, 54% and 15%, respectively) despite a similar training volume (1618 ± 468kg vs. 1638 ± 509kg). CSE was reduced during the RT session (~ 27%) but recovered ten minutes after, regardless of the environmental condition. SICI did not change after any RT session. The data suggest that acute exposure to moderate hypoxia slightly increased the excitability of the most excitable structures of the corticospinal tract but did not influence intracortical or corticospinal responses to a single RT session.

Differential responses from the left postcentral gyrus, right middle frontal gyrus, and precuneus to meal ingestion in patients with functional dyspepsia.

Functional dyspepsia (FD) is most often a meal-induced syndrome. Studies using resting-state functional magnetic resonance imaging (rs-fMRI) reported abnormal connectivity in areas related to pain processing in FD. However, only a few studies have attempted to determine how meal ingestion affects the brain's working patterns. Through rs-fMRI, this study observed how meal ingestion affected brain regions related to visceral hypersensitivity and emotional response networks in FD patients. A total of 30 FD patients and 32 healthy controls (HC) were enrolled and underwent clinical investigations. Rs-fMRI was performed twice after a 4-h fast and 50 min after a meal. The mean functional connectivity strength (FCS) values were extracted from brain regions with significant differences to show the trend of changes related to meal ingestion after FCS analyses. Depression, anxiety, sleep disturbances, and weight loss were more common in FD patients (P ≤ 0.001). Compared with HCs (corrected cluster P-value < 0.05), FD patients had significantly higher FCS in the right middle frontal gyrus before meals and higher meal-induced FCS in the left postcentral gyrus. HCs had greater meal-induced activation in the right precuneus and anterior cingulate cortex. FD patients had a decreasing trend in the right inferior frontal gyrus compared to the increasing trend in HCs. We only found anxiety to be negatively correlated with FCS in the right inferior frontal gyrus in FD (r = -0.459, p = 0.048, uncorrected). In this study, we discovered that FD patients have different perceptual and emotional responses to food intake in defined brain areas, providing promising impetus for understanding pathogenic brain mechanisms in FD.

Reconceptualizing destination image

ABSTRACT Our study aims to develop an index for measuring destination image perceptions based on data collected from three prime tourism destinations (destination A = 212, destination B = 194 and destination C = 176 responses) in India in the new normal. There are three studies based on self-reported measures conducted. While the first two studies collected perceptual responses from destinations A and B and were used to validate the factor structure of the destination image, the third study-based responses were used to assess the criterion validity of the destination image index. Our instrument shows that destination image is a second-order index composed of hygiene and vaccination, socio-political environment, natural environment, attractions, and value for money. Implications for managers and practitioners were also provided.

Acute Responses in Blood Flow Restriction Low-intensity Aerobic Training: A Meta-analysis.

The purpose was to determine the effect low-intensity training with blood flow restriction (LI-BFR) versus high-intensity aerobic training (HIT) on acute physiological and perceptual responses. The Cumulative Index to Nursing and Allied Health Literature, National Library of Medicine, Scopus, SPORTDiscus and Web of Science databases and the reference list of eligible studies were consulted to identify randomized experimental studies, published until July 4, 2022, that analyzed physiological or perceptual responses between LI-BFR versus HIT in healthy young individuals. Mean difference (MD) and standardized mean difference (SMD) were used as effect estimates and random effects models were applied in all analyses. Twelve studies were included in this review. During exercise sessions, HIT promoted higher values of heart rate (MD=28.9 bpm; p<0.00001; I 2 =79%), oxygen consumption (SMD=4.01; p<0.00001; I 2 =83%), ventilation (MD=48.03 l/min; p=0.0001; I 2 =97%), effort (SMD=1.54; p=0.003; I 2 =90%) and blood lactate (MD=3.85 mmol/L; p=0.002; I 2 =97%). Perception of pain/discomfort was lower in HIT (SMD=-1.71; p=0.04; I 2 =77.5%). In conclusion, LI-BFR promotes less pronounced physiological responses than HIT but with greater perception of pain.

Effects of phenylcapsaicin on aerobic capacity and physiological parameters in active young males: a randomized, triple-blinded, placebo-controlled, crossover trial.

Objective: Phenylcapsaicin (PC) is a new capsaicin analog which has exhibited a higher bioavailability. This sudy assessed the effects of a low dose (LD) of 0.625mg and a high dose (HD) of 2.5mg of PC on aerobic capacity, substrate oxidation, energy metabolism and exercise physiological variables in young males. Materials and methods: Seventeen active males (age = 24.7 ± 6.0years) enrolled to this randomized, triple-blinded, placebo-controlled, crossover trial. Participants attended the laboratory on 4 sessions separated by 72-96h. A submaximal exercise test [to determine maximal fat oxidation (MFO) and the intensity at MFO (FATmax)] followed by a maximal incremental test (to determine VO2max) were performed in a preliminary session. The subsequent sessions only differed in the supplement ingested [LD, HD or placebo (PLA)] and consisted of a steady-state test (60min at FATmax) followed by a maximal incremental test. Energy metabolism, substrate oxidation, heart rate, general (gRPE) and quadriceps (RPEquad) rate of perceived exertion, skin temperature and thermal perception were tested. Results: Clavicle thermal perception was lower in HD compared to PLA and LD (p = 0.04) across time. HD reduced maximum heart rate in comparison to PLA and LD (p = 0.03). LD reported higher general RPE (RPEg) values during the steady-state test compared to PLA and HD across time (p = 0.02). HD and LD elicited higher peak of fat oxidation during the steady-state test compared with PLA (p = 0.05). Intra-test analyses revealed significant differences for fat oxidation (FATox) in favor of HD and LD compared to PLA (p = 0.002 and 0.002, respectively), and for carbohydrate oxidation (CHOox) (p = 0.05) and respiratory exchange ratio (RER) (p = 0.03) for PLA. In the incremental test, only general RPE at 60% of the maximal intensity (W) differed favoring HD (p ≤ 0.05). Conclusion: Therefore, PC may contribute to increase aerobic capacity through the improvement of fat oxidation, maximum heart rate and perceptual responses during exercise.

Physiological and perceptual responses due to accidental water immersion

With the increasing global civil aviation business, water-related accidents in airplanes, often accompanied by accidental passenger waterfalls, are inevitable. Exposure to cold water can cause physiological and perceptual abnormalities that may endanger human health and safety. In this study, a water tank was constructed in a climate chamber to simulate accidental water immersion, and 10 healthy male subjects were recruited to investigate physiological and perceptual responses during air exposure and water immersion. Parameters such as core temperature, skin temperature, metabolic heat production, blood oxygen saturation, heart rate, respiratory rate, thermal sensation, thermal acceptance, and thermal comfort were continuously monitored. Statistical analysis revealed that skin temperature, metabolic heat production, and heart rate were the most sensitive parameters during water immersion. Changes in skin temperature were smallest in the leg (DTs ≈ 4 °C) and largest in the chest (DTs ≈ 9 °C) upon water immersion. There was a strong correlation between local thermal sensation and local skin temperature when subjects remained sedentary (R2 > 0.8). The use of a LP2 (life preserver, 0.20 clo) slightly improved local thermal comfort compared to LP1 (0.05 clo), suggesting that life preserver may compensate for the decrease in thermal comfort caused by immersion in water.

Association between physiological and perceptual heat strain while wearing stab-resistant body armor

In this study, we explored the association between physiological and perceptual heat strain while wearing stab-resistant body armor (SRBA). Human trials were performed on ten participants in warm and hot environments. Physiological responses (core temperature, skin temperature, and heart rate), and perceptual responses (thermal sensation vote, thermal comfort vote, restriction of perceived exertion (RPE), wetness of skin, and wetness of clothing) were recorded throughout the trials, and subsequently, the physiological strain index (PSI), and perceptual strain index (PeSI) were calculated. The results indicated that the PeSI showed a significant moderate association with the PSI, and was capable of predicting PSI for low (PSI = 3) and high (PSI = 7) levels of physiological strain with the areas under the curves of 0.80 and 0.64, respectively. Moreover, Bland-Altman analysis indicated that the majority of the PSI ranged within the 95% confidence interval, and the mean difference between PSI and PeSI was 0.14 ± 2.02 with the lower 95% limit and upper 95% limit being −3.82 to 4.10, respectively. Therefore, the subjective responses could be used as an indicator for predicting physiological strain while wearing SRBA. This study could provide fundamental knowledge for the usage of SRBA, and the development of physiological heat strain assessment.

Evaluation of the simulation based training quality assurance tool (SBT-QA10) as a measure of learners’ perceptions during the action phase of simulation

BackgroundIn an earlier interview-based study the authors identified that learners experience one or more of eight explicit perceptual responses during the active phase of simulation-based training (SBT) comprising a sense: of belonging to instructor and group, of being under surveillance, of having autonomy and responsibility for patient management, of realism, of an understanding of the scenario in context, of conscious mental effort, of control of attention, and of engagement with task. These were adapted into a ten-item questionnaire: the Simulation Based Training Quality Assurance Tool (SBT-QA10) to allow monitoring of modifiable factors that may impact upon learners’ experiences. This study assessed the construct validity evidence of the interpretation of the results when using SBT-QAT10.Materials and methodsRecently graduated doctors and nurses participating in a SBT course on the topic of the deteriorating patient completed the SBT-QAT10 immediately following their participation in the scenarios. The primary outcome measure was internal consistency of the questionnaire items and their correlation to learners’ satisfaction scores. A secondary outcome measure compared the impact of allocation to active versus observer role.ResultsA total of 349 questionnaires were returned by 96 course learners. The median of the total score for the ten perception items (TPS) was 39 (out of 50), with no significant difference between the scenarios. We identified fair and positive correlations between nine of the 10 items and the SBT-QA10-TPS, the exception being “mental effort”. Compared to observers, active learners reported significantly more positive perceptions related to belonging to the team and interaction with the instructor, their sense of acting independently, and being focused. The questionnaire items were poorly correlated with the two measures of global satisfaction.ConclusionExcept for the item for mental effort, the QA10-TPS measures learners’ experiences during the active phase of simulation scenarios that are associated with a positive learning experience. The tool may have utility to learners, instructors, and course providers by informing subsequent debriefing and reflection upon practice for learners and faculty. The relationship between these perceptions and commonly used measures of satisfaction remains poorly understood raising questions about the value of the latter.

Acute performance, physiological, and perceptual changes in response to repeated cycling sprint exercise combined with systemic and local hypoxia in young males

This study investigated the acute performance, physiological, and perceptual changes during repeated sprint exercise (RSE) under normobaric hypoxia and with blood flow restriction (BFR). Fourteen active males completed standardized RSE (6 × 10 s cycling sprints with 30 s passive rest) in three randomized conditions: under normobaric hypoxia (FiO2 ∼ 14.4%, HYP), normoxia (FiO2 ∼ 20.9%, SHAM), and with BFR (40% arterial occlusion pressure). The percentage decrement score of power output (Sdec) was used to quantify motor performance fatigue. During RSE, muscle oxygenation (total and oxygenated hemoglobin) and activity of the right quadriceps were measured. Perceived motor fatigue, physical strain, affective valence, and arousal were queried after each sprint. Blood lactate concentration (BLC) and peripheral oxygenation (SpO2) were measured before and after RSE. Sdec was greater in HYP and BFR compared to SHAM (p ≤ 0.008). BFR decreased mean power output (p < 0.001) and muscle activity (p = 0.027) compared to SHAM. Decrease in muscle oxygenated hemoglobin was higher in BFR during each rest (p ≤ 0.005) and in HYP during rest 4 (p = 0.006) compared to SHAM. HYP increased BLC and decreased SpO2 compared to BFR (p < 0.001) and SHAM (p = 0.002). There were no differences between conditions for any rating scale (p ≥ 0.060). HYP and BFR increased motor performance fatigue but with different physiological responses, whereas perceptual responses were unaffected during RSE.

Noise and vestibular perception of passive self-motion.

Noise defined as random disturbances is ubiquitous in both the external environment and the nervous system. Depending on the context, noise can degrade or improve information processing and performance. In all cases, it contributes to neural systems dynamics. We review some effects of various sources of noise on the neural processing of self-motion signals at different stages of the vestibular pathways and the resulting perceptual responses. Hair cells in the inner ear reduce the impact of noise by means of mechanical and neural filtering. Hair cells synapse on regular and irregular afferents. Variability of discharge (noise) is low in regular afferents and high in irregular units. The high variability of irregular units provides information about the envelope of naturalistic head motion stimuli. A subset of neurons in the vestibular nuclei and thalamus are optimally tuned to noisy motion stimuli that reproduce the statistics of naturalistic head movements. In the thalamus, variability of neural discharge increases with increasing motion amplitude but saturates at high amplitudes, accounting for behavioral violation of Weber's law. In general, the precision of individual vestibular neurons in encoding head motion is worse than the perceptual precision measured behaviorally. However, the global precision predicted by neural population codes matches the high behavioral precision. The latter is estimated by means of psychometric functions for detection or discrimination of whole-body displacements. Vestibular motion thresholds (inverse of precision) reflect the contribution of intrinsic and extrinsic noise to perception. Vestibular motion thresholds tend to deteriorate progressively after the age of 40 years, possibly due to oxidative stress resulting from high discharge rates and metabolic loads of vestibular afferents. In the elderly, vestibular thresholds correlate with postural stability: the higher the threshold, the greater is the postural imbalance and risk of falling. Experimental application of optimal levels of either galvanic noise or whole-body oscillations can ameliorate vestibular function with a mechanism reminiscent of stochastic resonance. Assessment of vestibular thresholds is diagnostic in several types of vestibulopathies, and vestibular stimulation might be useful in vestibular rehabilitation.