Overweight and obesity are growing concerns that also affect nursing staff, healthcare professionals that play a critical role in public health awareness and intervention. This study aimed to define the health parameters associated with body weight, analyze if there is an erroneous self-perception of overweight/obesity through the distortion of body weight perception, and determine the predictive factors of body weight distortion. A cross-sectional study of 224 nursing students gathered anthropometric and demographic data. Self-perceived body weight was assessed using Stunkard and Stellar's scale. Descriptive statistics and multinomial logistic regression identified significant predictors of weight distortion. The analysis found that men reported greater weight discrepancies than women. Specifically, 57% of the men (28 of 49 participants) underestimated their real BMI, while only 23% of the women (40 of 175 participants) did so. Age, sex, and weight classification emerged as significant explanatory variables for the distortion of body weight perception. The findings indicate a significant vulnerability among nursing students to the misperception of their own body weight status, highlighting the need for targeted training strategies. These strategies should focus on correcting misperceptions of obesity among health professionals throughout their working life to improve future obesity prevention efforts for society.