The quality of sexual life of women with type 2 diabetes has an impact on their self-management perceptions. To evaluate the effect of quality of sexual life on self-care perceptions of women with type 2 diabetes mellitus (DM). It was an online descriptive study of 127 women with type 2 DM. The questionnaire consisted of a patient information form, sexual quality of life scale-female, and diabetes self-management perception scale. There was a significant relationship between diabetes self-management perception and sexual quality of life (P = 0.000). The individuals' diabetes self-management perception scores differed significantly according to their age (F = 3.12; P = 0.047), and the sexual quality of life scores differed significantly according to their treatment type (F = 4.01; P = 0.020). There is a relationship between quality of sexual life and self-management perceptions of women with type 2 DM. As the quality of sexual life increases, diabetes self-management perceptions increase. Age affects diabetes self-management perception, and the type of treatment used by individuals also affects their quality of sexual life.