Asthma is a prevalent and persistent condition affecting the respiratory system, defined by the presence of fluctuating and reversible symptoms associated with the restriction of airflow, heightened sensitivity of the bronchial tubes, and inflammation within the airways. Saudi Arabia has a high prevalence of this chronic illness, making it one of the most often seen conditions in the country. A popular therapeutic approach within the realm of complementary and alternative medicine for individuals with asthma is the use of herbal medications. Nevertheless, the efficacy of these medicines in treating asthma is often supported by inadequate data. This study aimed to determine the knowledge, attitude, and perception of parents toward the use of herbal medicines in the treatment of asthma in their children in the Najran Region. In this cross-sectional study, the participants received an electronic self-administered survey via social media channels. The survey instrument comprises a set of questions that have been gathered from prior studies that have comparable research aims. The questionnaire sheet will contain three parts. Data were analyzed with IBMSPSSStatistics for Windows, Version 22 (Released 2013; IBM Corp., Armonk, New York, United States). The sample and outcome variables were summarized using the descriptive statistics of frequencies, percentages, means, and standard deviations. Data were analyzed by type of provider as appropriate, and the Pearson chi-square test was used to compare the observed data; the paired sample t-test was used to test the difference between the means of the pretest and post-test. Fifteen percent of the respondents personally suffer from asthma, while 85.0% do not. Additionally, 25.7% of the respondents indicated that one of their children suffers from asthma, while 74.3% stated that their children do not suffer from asthma.The data also showthat the statement "Asthma symptoms are dry cough, shortness of breath, and wheezing" received a 51.4% "Strongly Agree" response, 37.9% "Agree," 9.3% "Neutral," 0.9% "Disagree," and 0.5% "Strongly Disagree." The majority of respondents (51.4%) reported obtaining information about asthma from doctors. A notable portion of respondents (35.5%) reported using herbs or folk medicines to treat asthma in their children. A substantial portion of respondents (44.9%) reported not using medicinal herbs at all. Despite this, 41.6% of respondents expressed belief in the idea of taking herbs as a treatment. In conclusion, the knowledge, attitude, and perception of parents towardthe use of herbal medicine in the treatment of asthma in their children are multifaceted and influenced by cultural, social, and individual factors. Understanding these dynamics is essential for developing culturally sensitive healthcare interventions and policies that align with the beliefs and practices of the community.