This study investigates the relationship between hotel employees’ perceptions of organizational politics, organizational silence, organizational cynicism, and innovation resistance. For this purpose, subjects (n = 351, 235 men and 116 women) from four-star hotels in Seoul, Incheon, Gyeonggi-do, and Jeju-do in South Korea were surveyed. The following four hypotheses were presented to achieve this study’s goal. First, the perception of organizational politics has a positive effect on organizational silence. Second, organizational silence positively affects organizational cynicism. Third, organizational silence has a positive effect on innovation resistance. Fourth, organizational cynicism positively affects innovation resistance. The results of hypothesis testing reveal that all hypotheses except for the fourth one are accepted. This study’s findings suggest that hotels should provide a work environment that is free from unfair organizational political activities.