Percentage Of Content Research Articles

Transforming Thai University Demonstration Schools into Learning Communities: A User Experience and Design-Based Research Approach

This study aimed to develop a model for the administration of demonstration schools in public universities based on the concept of "School as a Learning Community" (SLC). The research utilized user experience and design-based research in three phases. Phase 1 involved analyzing the current administrative practices of school administrators under the SLC framework with a sample of 5 administrators. Phase 2 focused on developing a model for promoting SLC-based school administration, targeting 63 participants, including administrators and teachers from Ramkhamhaeng University Demonstration School, Bangna Campus. Phase 3 evaluated the feasibility and suitability of the developed model using a sample of 657 stakeholders, including seven administrators, 52 teachers, and 598 parents of students in grades 1–5. Research tools included interviews and questionnaires, with data analyzed through content analysis, percentages, mean scores (M), and standard deviations (SD). The findings revealed: (1) user experiences highlighted key practices such as inclusive decision-making, shared learning spaces, and stakeholder collaboration, (2) eighteen prototype models for SLC-based administration were developed, integrating stakeholder-driven vision, excellence-focused philosophy, and professional learning community activities, (3) stakeholders most preferred Model 17, selected by 19.33%, emphasizing a shared vision (A2), the philosophy of excellence (B3), and collaborative activity systems (C2), and (4) expert evaluations showed high feasibility (97.40%) and suitability (96.10%) of the proposed model. This study contributes to the literature by providing an actionable framework for transforming demonstration schools into thriving learning communities and fostering collaboration among diverse stakeholders to enhance educational quality and administration efficiency.

Harnessing Grape Pomace, a Multifunctional By-Product from the Wine Industry for High-Value Salad Dressings

Grape pomace (GP) has gained attention for its potential to be valorized into functional foods due to its rich composition of bioactive compounds. In this work, GP has been exploited to develop plant-based mayonnaise alternatives and salad dressings. The influence of the water-to-oil ratio, percentage content of GP, lecithin, and vinegar on the viscosity and physical stability of the obtained emulsions have been investigated by the Design of Experiments. Two formulations, one high-oil (70%) and the second high-water (60%), were further studied for their potential applications. The selected samples were subjected to an accelerated stability test (60 °C for 21 days) to verify the influence of GP on oxidation protection. The high-water sample, combined with 8% GP, showed lower primary (peroxide value < 20 mEq O2/kg fat) and secondary oxidation (anisidine value < 55) parameters than the high-oil sample, highlighting the GP antioxidant activity. The phenolic profile of all samples by HPLC was also determined. Lastly, a sensory analysis was conducted, showing the highest overall acceptability for the oil-rich sample. The obtained results contribute to highlighting the potentiality of GP in the formulation of healthy foods, adopting the zero-waste approach for the full exploitation of this underutilized resource.

Ultra-low-dose coronary CT angiography via super-resolution deep learning reconstruction: impact on image quality, coronary plaque, and stenosis analysis.

To exploit the capability of super-resolution deep learning reconstruction (SR-DLR) to save radiation exposure from coronary CT angiography (CCTA) and assess its impact on image quality, coronary plaque quantification and characterization, and stenosis severity analysis. This prospective study included 50 patients who underwent low-dose (LD) and subsequent ultra-low-dose (ULD) CCTA scans. LD CCTA images were reconstructed with hybrid iterative reconstruction (HIR) and ULD CCTA images were reconstructed with HIR and SR-DLR. The objective parameters and subjective scores were compared. Coronary plaques were classified into three components: necrotic, fibrous or calcified content, with absolute volumes (mm3) recorded, and further characterized by percentage of calcified content. The four main coronary arteries were evaluated for the presence of stenosis. Moreover, 48 coronary segments in 9 patients were evaluated for the presence of significant stenosis, with invasive coronary angiography as a reference. Effective dose decreased by 60% from LD to ULD CCTA scans (2.01 ± 0.84 mSv vs. 0.80 ± 0.34 mSv, p < 0.001). ULD SR-DLR was non-inferior or even superior to LD HIR in terms of image quality and showed excellent agreements with LD HIR on the plaque volumes, characterization, and stenosis analysis (ICCs > 0.8). Moreover, there was no evidence of a difference in detecting significant coronary stenosis between the LD HIR and ULD SR-DLR (AUC: 0.90 vs. 0.89; p = 1.0). SR-DLR led to significant radiation dose savings from CCTA while ensuring high image quality and excellent performance in coronary plaque and stenosis analysis. Question How can radiation dose for coronary CT angiography be reduced without compromising image quality or affecting clinical decisions? Finding Super-resolution deep learning reconstruction (SR-DLR) algorithm allows for 60% dose reduction while ensuring high image quality and excellent performance in coronary plaque and stenosis analysis. Clinical relevance Dose optimization via SR-DLR has no detrimental effect on image quality, coronary plaque quantification and characterization, and stenosis severity analysis, which paves the way for its implementation in clinical practice.

Formulation and Evaluation of Polyherbal Antidandruff Shampoo

Introduction: Nowadays, most people are suffering from dandruff which when not treated becomes flaky and causes major damage to the scalp of a person. Dandruff is a common scalp illness caused by the yeast Pittosporum. It is not possible to completely eradicate dandruff; it can only be appropriately handled. Methods: When used as indicated, a shampoo's surfactant, often referred to as a surface-active agent, in its proper form—liquid, solid, or powder—will safely remove skin fragments, dirt, and surface oil from the scalp and hair shaft. Numerous hair care solutions use a variety of anti-fungal substances to treat dandruff. Many adverse reactions to these products have been reported, includ-ing hair loss, heightened headache, nausea, scaling, itching, and irritation. Results: Thus, an attempt was undertaken to develop a herbal anti-dandruff shampoo form safe and more successful in treating the dandruff problem by using a marketed herbal tincture. The anti-dandruff formulation was prepared by combining natural polyherbal tincture, and these tincture shows the different medicinal effects on hair. Conclusion: A number of parameters, including visual observation, pH, consistency, particle per-centage, filth dispersion, surface phenomena, and foaming content were used to assess the shampoo formulations. Also, the estimation of an anti-microbial activity by using the inoculation method. The greatest zone of inhibition demonstrated a strong antimicrobial effect for the formulation.

Analisis Perbedaan Kadar Nikel Antara Front Penambangan dan Stockpile Pada PT Rockstone Multi Mining Indonesia

PT Rockstone Multi Mining Indonesia Central Sulawesi is one of the companies that manages laterite nickel ore into ferronickel (FeNi) products. This study aims to determine the percentage of nickel content found in the mining front to the stockpile and to find out what percentage of the change in nickel content from the mining front to the stockpile and analyze the factors of the change in the level from the mining front to the stockpile. This study uses the field observation method. In the mining front data , with a total of 17 domes, the average level of Ni Front of reclamation is 1.91 while the average level of Ni stockpile is 1.90. When summing up the average value of the mining front and stockpile levels , a decrease in nickel content of 0.01% was obtained. The factors that cause changes in nickel levels are waterlogging, dredging of the Stockpile floor, the use of used sacks for samples, unclean buckets, unclean dump truck tubs, sampling errors, and preparation errors.

Studi Kualitas Aspal Buton PT Wijaya Karya Bitumen, Kabupaten Buton, Provinsi Sulawesi Tenggara

Utilization of Buton asphalt is not too maximal, it is because the quality of Buton asphalt is considered less favorable than asphalt oil. The aim of this study was to determine the percentage content of bitumen and water content at the mine site and Lawele Kabungka. Methodology The study was entirely based on laboratory data required data¬-related data quality is seen from the Buton asphalt bitumen content and moisture content of the samples taken in the field. In addition, data were also taken from the test results Research and Development Center (PUSLITBANG) Department of Public Works (PU) in the form of data ductility, penetration, flash point, softening point, lose weight, solubility in CCl4 on the content of the asphalt in two locations: Lawele and Kabungka , Based on the results of research conducted in the laboratory PT. Wijaya Karya Bitumen bitumen shows that the average levels for Lawele Buton Asphalt Bulk 28.79% and Lawele (LGA) 29.53%, while in Kabungka with an average of Buton Asphalt Bulk 25.52% and Kabungka (BGA) 26 , 83%. Both locations meet ISO standards, both asphalt in bulk form or in the form of LGA and BGA is 25%. Buton asphalt water content is quite high at the location Lawele (Buton Asphalt Bulk of 13.2%, LGA of 7.93%) and Kabungka (Buton Asphalt Bulk 11.03% BGA 8.9%). The water content of the two locations do not meet the National Standards of Indonesia (SNI) either in bulk form or in the form of BGA and LGA is constant below 2%.

A review in pollen grains for plants

Ripe pollen's primary morphological, cytological, and physiological characteristics are explained, contrasted, examined, and explored alone, in various combinations, and in relation to the female counterpart as well as the biotic and abiotic environmental factors. The goal is to attempt and figure out why pollen grains have the same reproductive function yet differ greatly in morphology and physiology during dispersal. One or more grain types per species, size and shape, number of cells, pollen dispersal unit types, sporoderm stratification, furrows, colpori, and other apertures, pollen presentation and array, water content percentage, mature pollen reserves, and osmotics are among the characteristics taken into consideration. Some pollen characteristics are related to each other, while others are tied to the female counterpart or competition between males and females, and still others are related to the many elements of the species' habitat, flowering season, and pollen presentation time.

Comparative evaluation of quantitative, and qualitative attributes of oat (Avena sativa L.) varieties grown in semi-arid India

Oat is a valuable cereal of Poaceae family, which is progressively used as an elite healthy diet, as a source of protein, minerals and dietary fiber. The agro-morphological characteristics and variation in quality attributes were studied to understand the extent of variability in these traits. Morphological study revealed significant variations among the tested varieties. The yields of oat oils were varied from 2.49 to 5.91%. The Kent (5.02%), JHO-822 (5.64%), and JHO 99-2 (5.91%) were contains more than two-fold oil content as compared to JHO 99-1 (2.49%). The compositions of fatty acids such as PUFA (poly-unsaturated fatty acid) (36.5–40.08%), MUFA (mono-unsaturated fatty acid) (33.06–37.58%), and SFA (saturated fatty acid) (17.27–25.42%) were showed significant variations. The oats oil was constituted about 70% of unsaturated fatty acids (UFA) with good amounts of PUFA including linoleic acid (36.0–39.35%) and linolenic acid (0.42–0.73%). The varieties JHO-2004 (12.62%), JHO-2012-2 (12.53%) and JHO-851 (11.21%), contains higher amount of proteins. The oat varieties were contained high amounts of UFA (⁓ 70%) with good amounts of protein, which made it an ideal cereal for nutraceutical applications. Among these varieties, the JHO 99-2 and JHO-851 were superior due to high oil yield (5.91, 4.02%), PUFA (38.47, 40.08%) content, and good percentage of protein (10.24, 11.21%). The data on quantitative and qualitative attributes suggested that the JHO-851 and JHO-99-2 can be used as dual purpose and also recommended as super food.

Karakteristik Mineral Pembawa Pasir Besi Daerah Pantai Pancana Kabupaten Barru Provinsi Sulawesi Selatan

Iron sand is one of the industrial minerals. The utilization of iron sand in Indonesia is still limited to being used as a raw material for cement factories in the manufacture of concrete. Iron is given the symbol (Fe) in the periodic table's chemical element. The purpose of this study was to determine the mineral properties of iron sand and the chemical characteristics of iron sand. The research location is in the Barru district in the province of South Sulawesi, Indonesia. This research method uses XRD and XRF analysis methods. From the results of the XRD analysis, it was found that 2 minerals carrying iron sand, including the minerals Magnetite and Hematite with the percentage content of these minerals, are. Magnetite mineral (Fe3O4) 9,3% and Hematite mineral (Fe2O3) 0,3%. The results of XRF analysis show that the chemical composition contained in F2O3 minerals, containing oxide and hydroxide elements Fe, O, and Oxide, is a chemical compound that contains at least one oxygen atom and at least one other element.

АНАЛІЗ ВІКОВОЇ ДИНАМІКИ ПОКАЗНИКІВ СКЛАДУ ТІЛА ЮНИХ ГІМНАСТОК-ХУДОЖНИЦЬ РІЗНОЇ КВАЛІФІКАЦІЇ

The article provides a general analysis of body composition indicators and determines their ratio in 6-9 year old gymnasts, and compares the obtained values, namely, body height, weight, body mass index, percentage of fat and skeletal muscle, energy expenditure at rest, and visceral fat level. The purpose of the research is to analyze body composition indicators in the age dynamics of 6-9-year-old artistic gymnasts of various sports qualifications. Material and methods of the study. The study involved 37 girls aged 6-9 who engaged of artistic gymnastics in the city of Vinnytsia and the city of Kozyatyn (Vinnytsia region). Research methods: analysis of scientific-methodical and special literature, method of assessing the component composition of the body of artistic gymnasts using the device OMRON, mathematical processing of empirical data. Results. It has been established that the average indicators of body composition monitoring of female gymnasts-artists gradually increase with age, namely, body length, body weight, body mass index, fat percentage. Other monitoring indicators - the percentage content of skeletal muscles, the level of visceral fat and energy expenditure at rest are determined by a decrease in indicators from the 8th to the 9th year. According to tabular data, it was found that the average indicators obtained from the body mass index in all four age groups of gymnasts have an "insufficient" level, and the percentage of fat in gymnasts aged 6 and 7 is "low". Conclusions. Achieving success in artistic gymnastics largely depends on the size, physique, and body composition of the gymnast. Therefore, a combination of external parameters and body composition will provide more accurate information about the gymnast's capabilities at a certain stage of sports training.

Proximate Analysis, Total Phenolic Content, and Antioxidant Activity of Wild Carob Pulp from Three Mediterranean Countries

(1) Background: Carob tree (Ceratonia siliqua L.) pulp is of great interest nowadays due to its nutritional benefits and diverse utilization in the food process. The nutritional and antioxidant properties of carob pulp in the Mediterranean have been assessed in several studies. Still, few studies have combined, within the same work, a comprehensive analysis of the chemical composition of carob pulp from fruits of natural populations across different countries of the Mediterranean basin, while also incorporating new research areas. (2) Methods: In the present work, we evaluated the nutritional value, total phenolic compounds, and antioxidant activity of carob pulp derived from wild populations of carob trees from three Mediterranean countries: Lebanon, Spain, and Morocco; (3) Results: All assessed bromatological characteristics, with the exception of ash and fiber content, revealed significant differences in the carob pulp from the three countries under study. High variability was observed for the total polyphenols ranging between 5.05 mg/g and 12.70 mg/g. Sucrose was the predominant sugar quantified ranging between 13.70 g/100 g and 28.10 g/100 g. The lipid content was low (0.26–0.36%). The moisture content of carob pulp ranges between 4.36% and 6.40%. Carob pulp presented a rich composition in fiber, with an average of 35.87%. The ash content was between 2.52% and 3.28%. The percentage of the protein content of the carob pulp ranged between 4.40 and 5.52, with an average carbohydrate value of 74.71%; (4) Conclusions: Spanish wild carob pulp samples offered higher carbohydrates contents and values for sucrose, fructose, and glucose, polyphenol content, and antioxidant activity, whereas Moroccan samples had higher values of carbohydrates and in concrete, the monosaccharides fructose and glucose showed higher contents in proteins and lipids. In contrast, Lebanese samples exhibit a high content of the disaccharide sucrose. These findings could be exploited in breeding programs to improve varieties that balance both the agronomical quality and nutritional values of carob pulp.

Effect of Peanut Intercropping on Arsenic Uptake and Remediation Efficiency of Plants in Arsenic-Contaminated Soil

Phytoremediation is an economically viable and environmentally friendly technique among various arsenic-contaminated soil remediation technologies. Field plot experiments were conducted to investigate the effects of peanut intercropping with sunflower, lucerne, and jute on the growth and development of intercropped crops and the efficiency of arsenic (As) remediation in polluted soil within the intercropping system. The results indicate that intercropping peanuts with other crops can enhance the biomass and yield of the crops. The land equivalent ratios (LER) of the three intercropping patterns were 1.03, 1.70, and 1.17, respectively. The intercropping pattern also influences the absorption and accumulation of As in crops. Total arsenic accumulation in peanuts intercropped with jute reached 493 μg·plant−1, which was significantly higher by 29.5% compared to peanut monoculture. Additionally, the translocation factor (TF) and bioaccumulation factor (BCF) of peanut seeds were significantly higher in peanut-jute intercropping compared to other treatments, but the As content of peanut seeds in all treatments complied with national food safety standards (GB2762-2022, 0.5 mg·kg−1). Intercropping of peanuts altered the pH and Eh values of rhizosphere soil, further influencing the percentage content of various forms of As in the soil, and reducing the mobility and effectiveness of As. The metal removal equivalent ratios (MRER) for the three intercropping patterns were 1.30, 2.11, and 1.26, respectively. The intercropping of peanuts and lucerne resulted in an MRER of 2.11. It indicates that peanut intercropping has a significant promotion and high restoration efficiency on the growth and development of lucerne. Therefore, among the three patterns, the peanut intercropping lucerne pattern has the best effect in applying to contaminated soil, and can better realize the integration of economic and ecological benefits.

Evaluation of nutritional, anthropometric, and psychological outcomes in different metabolic and bariatric surgery techniques: a follow up study

BackgroundMetabolic and bariatric surgery (MBS) is a suitable solution for the treatment of morbid obesity. Investigating an MBS method that has the best outcomes has always been the main concern of physicians. The current study aimed to compare nutritional, anthropometric, and psychological complications of individuals undergoing various MBS Techniques.MethodsA total of 96 subjects, who had been already referred to the obesity clinic of Firoozgar Hospital, Tehran, Iran, for MBS, were selected for the study and were followed for one year after MBS. The dietary intakes of the participants were assessed using a Food Frequency Questionnaire (FFQ) on a daily, weekly, monthly, or yearly basis. The mental health of participants was done via the Symptom Checklist 90 Revised. Furthermore, the In-Body 720 bioelectrical impedance device was used to obtain the body composition of the participants at the beginning and the end of the study.ResultsThe mean age of the participants was 39.5 ± 9.5 years. All anthropometric indices including weight, Body Mass Index (BMI), protein content, fat mass, and fat mass percentage decreased after Roux-en-Y gastric bypass (RYGB), one-anastomosis gastric bypass (OAGB), and sleeve gastrectomy (SG) surgeries (P < 0.05). After adjustments for confounders, no significant difference was observed in the magnitude of the changes in body composition between the three Techniques (p > 0.05). Energy and carbohydrate intake significantly decreased after surgeries in all three groups (p < 0.05), but comparing the methods no significant difference was revealed (p > 0.05). Furthermore, the results indicated that there was a significant relationship between the mental health of patients before and after surgeries (p < 0.05).ConclusionOverall, all three methods of surgery contributed to the improvement of the nutritional, anthropometric, and psychological complications. Further complementary studies are needed to determine the least complicated MBS method.

Effects of Waste Fibers from Calamus Rotang on the Physical and Mechanical Characterizations of Compressed Earth Blocks Manufactured with the Elastic Soil of Western Region of Cameroon

Objective: In order to promote local materials in Cameroon, rattan waste is used to reinforce compressed earth blocks (CEB). The main objective of this work is to study the effect of rattan waste on the physical and mechanical properties of CEB. Methods: The raw materials, namely the soil sample and rattan waste fibers, are collected in the western region of Cameroon, more precisely in Bangangté. In the laboratory, the soil samples were analyzed; the analyses include the granulometric analysis, the Atterberg limits, and the Proctor test. Different percentages of rattan waste contents were substituted in place of sand, that is, 0%, 2%, 4%, and 6%. These different samples were characterized in the laboratory through different tests, mechanical and physical. Results: The better mechanical characteristics are obtained for blocks reinforced with 2% rattan waste, with 0.70MPa in three-point bending and 3.04MPa in compression, respectively. Thus, the presence of rattan wastes has a positive effect on the mechanical behavior of the composite by increasing its ductility compared to that of the control block. Conclusion: The mechanical properties of the compressed soil block (CSB) improve with the incorporation of rattan wastes, which are optimal for a content of 2%. However, they increase the porosity of the material and thus its sensitivity to water, on the contrary to the control CSB.

Post-Industrial Recycled Polypropylene for Automotive Application: Mechanical Properties After Thermal Ageing

The transport sector’s impact on climate change and energy-related greenhouse gas (GHG) emissions has raised significant concerns, prompting the automotive industry to transition towards greener solutions. This includes producing lighter vehicles with sustainable materials, like recycled plastics. Understanding the behavior of these new recycled compounds is crucial, especially regarding their response to ageing and stress conditions throughout a vehicle’s lifecycle. This study aims to investigate the mechanical property variations of virgin and recycled talc-filled polypropylene (PP) compounds used in the automotive industry, emphasizing the effects of thermal ageing after recycling. Polypropylene samples with different talc concentrations and post-industrial recycled content percentages are examined. Thermal (TGA and DSC) and spectral (FT-IR) analysis reveal structural changes due to recycling-induced thermo-mechanical degradation. A multi-axial impact test shows varied ductile and brittle behaviors between virgin and recycled PP, influenced by filler content. Impact strength, tensile, and flexural properties are assessed, highlighting differences between virgin and recycled PP, but maintaining properties over ageing time. Despite thermo-oxidative degradation from recycling and thermal ageing, the mechanical performance of recycled polypropylene materials remains unaffected, making them a viable sustainable alternative for the automotive industry.

Standardization of 96% Ethanol Extract of Beluntas Leaves, Kenikir Leaves, and Purple Corn Kernels

Beluntas (Pluchea indica) leaves, kenikir (Cosmos caudatus) leaves, and purple corn (Zea mays) kernels have the potential to be developed into preparations of traditional medicine, which requires standardization of raw materials. The 96% ethanol extract P. indica leaves from Batu, C. caudatus leaves from Wonosari, and purple corn kernels from Sukabumi have been standardized. Both specific and non-specific requirements are covered. Fragment identifiers of P. indica leaves, such as stomata and trichoma. C. caudatus leaves, such as vascular tissue with stair thickening and multicellular hair covering. Purple corn kernels such as amylum and hilum in the form of stars. The thick extracts were obtained from the results of ultrasonic-assisted extraction with yields of 14.76% for P. indica leaves, 7.49% for C. caudatus leaves, and 5.79% for purple corn kernels. The organoleptic of ethanolic extract P. indica leaves is thick and greenish-black, C. caudatus leaves is thick and brown, and purple corn kernels is thick and purple. The water-soluble content from P. indica leaves, C. caudatus leaves, and purple corn kernels was 13.85%, 11.13%, and 10.62%, respectively. The ethanol soluble content was 16.58%, 14.87%, and 15.89%. The total ash content for P. indica leaves, C. caudatus leaves, and purple corn kernels was 15.04%, 9.37%, and 4.76%. The percentage of water content was 9.07%, 14.34%, and 11.12%. The standardized data collected was compared with the requirements in the official monographs of Materia Medika Indonesia and Farmakope Herbal Indonesia. The results showed that the three samples used had met most of the standardization parameters and could be developed into traditional medicine.

Harnessing the nutraceutical and antioxidant potential of the sporocarp of medicinal mushrooms, Schizophyllum commune Fr.

The split gill mushroom, Schizophyllum commune Fr., naturally occurs on decaying wood during the rainy season and is consumed as a food source in many parts of North-East India due to its medicinal properties. In the present study, an isolate of S. commune was analysed for its proximate composition and nutraceutical potential to support the development of biofortified products. The proximate composition analysis of dried and fresh mushrooms of S. commune revealed the following results: carbohydrate content (74.00% and 30.51 %, respectively), calorific value (358.00 and 148.84 Kcal/100g, respectively), crude fiber (3.08 % and 1.20% respectively), crude protein content (13.70 % and 6.18%, respectively), and total antioxidant activity (1267.00?g/g and 1090.76?g/g, respectively). Glycemic potential assessments indicated that S. commune exhibited a low glycemic index of 10.33 and total starch digestibility of 7.65%. The nutraceutical analysis of dried S. commune powder in different solvent extracts (methanol, ethanol, and ethyl acetate) demonstrated that methanolic extracts recorded the highest DPPH inhibition percentage (89.60%), reducing power (37.20%), and phenolic content (0.230±0.005 mg/mL). Methanolic extracts also exhibited higher flavonoid content (0.455±0.003mg/mL). Ethanolic extracts were found to have the highest total tannin (0.250±0.001mg/mL) and saponin content (0.303±0.001mg/mL). A herbal infusion formulated with S. commune dried powder, dried basil leaf powder, and dried ginger powder demonstrated high antioxidant and phytochemical properties. Sensory evaluation of two treatments of the herbal infusion indicated good overall acceptability, highlighting its potential as a commercially viable fortified product with significant antioxidant properties.

The challenges of evidence-based prehabilitation in a real-life context for patients preparing for colorectal surgery—a cohort study and multiple case analysis

BackgroundMultimodal prehabilitation programs are effective at reducing complications after colorectal surgery in patients with a high risk of postoperative complications due to low aerobic capacity and/or malnutrition. However, high implementation fidelity is needed to achieve these effects in real-life practice. This study aimed to investigate the implementation fidelity of an evidence-based prehabilitation program in the real-life context of a Dutch regional hospital.MethodsIn this observational cohort study with multiple case analyses, all patients who underwent colorectal surgery from January 2023 to June 2023 were enrolled. Patients meeting the criteria for low aerobic capacity or malnutrition were advised to participate in a prehabilitation program. According to recent scientific insights and the local care context, this program consisted of four exercise modalities and three nutrition modalities. Implementation fidelity was investigated by evaluating: (1) coverage (participation rate), (2) duration (number of days between the start of prehabilitation and surgery), (3) content (delivery of prescribed intervention modalities), and (4) frequency (attendance of sessions and compliance with prescribed parameters). An aggregated percentage of content and frequency was calculated to determine overall adherence.ResultsFifty-eight patients intended to follow the prehabilitation care pathway, of which 41 performed a preoperative risk assessment (coverage 80%). Ten patients (24%) were identified as high-risk and participated in the prehabilitation program (duration of 33–84 days). Adherence was high (84–100%) in five and moderate (72–73%) in two patients. Adherence was remarkably low (25%, 53%, 54%) in three patients who struggled to execute the prehabilitation program due to multiple physical and cognitive impairments.ConclusionImplementation fidelity of an evidence-based multimodal prehabilitation program for high-risk patients preparing for colorectal surgery in real-life practice was moderate because adherence was high for most patients, but low for some patients. Patients with low adherence had multiple impairments, with consequences for their preparation for surgery. For healthcare professionals, it is recommended to pay attention to high-risk patients with multiple impairments and further personalize the prehabilitation program. More knowledge about identifying and treating high-risk patients is needed to provide evidence-based recommendations and to obtain higher effectiveness.Trial registrationNCT06438484.

Formulation and Evaluation of Capsaicin Transemulgel for the Treatment of Arthritis

Capsaicin (CAP)is a non-narcotic analgesic and anti-inflammatory drug used to relieve pain and inflammation associated with rheumatoid arthritis. Transemulgel is a new approach with combination emulsion and gel base having special characteristics dual controlled release for the treatment of various conditions arthritis. The present research work, a novel transemulgel with CAP (F1-F6) was formulated by using different concentration of gellan gum (GG) and xanthan gum (XG) as gelling agents with oil in water emulsion base. No significant drug-excipient interactions were observed in FT-IR studies. To evaluate various characterizations of transemulgel such as pH, spreadability, viscosity, gelation time, drug content, Invitro drug release of gel was examined in phosphate buffer pH-7.4 by Franz diffusion cell technique. The optimized transemulgel of (F5) showed pH of 5.8 ± 0.52 and viscosity of2840 ± 0.65cps. The percentage of drug content in the formulated transemulgel (F1-F6) was observed in the range of 84 to 96%w/w respectively. The optimal transemulgel spreadability was found to be 22.23 ± 0.25g·cm/s. The percentage of cumulative drug release from the formulations (F1-F3) were found to be in the range between 72.85 to 62.18% w/w and the batches (F4-F6) were observed in the range 76.85 to 70.66%w/w at the end of 6h.By considering all the investigated data while increase in concentration of GG and XG were influenced rheological properties, drug content efficiency, the Invitro drug release of transemulgel. The present investigate suggest that the CAP loaded transemulgel can be a promising topical delivery to relieve pain, inflammation and provided greater bioavailability to improve therapy. Keywords: Topical delivery, Transemulgel, Capsaicin, Xanthan gum, Gellan gum, Emulsion, Arthritis

Characterization of Soil Enhancement Mixtures at Low-Magnitude Currents

Regarding the installation of grounding systems, it is not common for the installation site to be re-located due to high soil resistivity. Enhancement materials have been widely used for their known advantages, including their ability to reduce the resistivity of soil. Although some studies have been conducted on the characterization of EMs under AC of various frequencies, limited studies can be found on their performance when mixed with various percentages of water content (WC) and soil. In this work, sand mixed with controlled percentages of enhancement materials (EM 1, EM 2 and EM 3) and controlled amounts of water content was placed on a parallel plate and tested under AC of various frequencies to obtain the resistivity and permittivity. It was found that dry sand–EM mixtures can be represented by an R-C parallel circuit, while wet sand–EM mixtures can be represented by a nonlinear R. These new test data providing the soil resistivity and permittivity of various sand–EM mixtures are important in selecting suitable EMs to be used in grounding systems.