Effective Penetration Research Articles

Overview of Vivaldi Antenna Selection for Through-Wall Radar Applications

This paper analyzes broadband antennas, with a special focus on Vivaldi antennas, for their suitability for through-wall radar applications. It assesses various antenna designs, emphasizing high gain, wide impedance bandwidth, and effective wall penetration capabilities. Vivaldi antennas are superior due to their broad bandwidth, high gain, and directional radiation patterns. This study further explores structural optimizations, feeding techniques, and performance enhancement strategies to refine Vivaldi antenna designs for through-wall radar systems. Through a comparative analysis and technical evaluation, this paper highlights Vivaldi antennas’ potential for improving through-wall radar systems’ imaging and sensing capabilities. This presents a pathway for future ultra-wideband advancements.

Skin-permeable gold nanoparticles with modifications azelamide monoethanolamine ameliorate inflammatory skin diseases

BackgroundTraditional topical drug delivery for treating inflammatory skin diseases suffers from poor skin penetration and long-term side effects. Metal nanoparticles show promising application in topical drug delivery for inflammatory skin diseases.MethodsHere, we synthesized a new type of nanoparticles, azelamide monoethanolamine-functionalized gold nanoparticles (Au-MEA NPs), based on citrate-capped gold nanoparticles (Au-CA NPs) via the ligand exchange method. The physical and chemical properties of Au-CA NPs and Au-MEA NPs were characterized. In vivo studies were performed using imiquimod-induced psoriasis and LL37-induced rosacea animal models, respectively. For in vitro studies, a model of cellular inflammation was established using HaCaT cells stimulated with TNF-α. In addition, proteomics, gelatin zymography, and other techniques were used to investigate the possible therapeutic mechanisms of the Au-MEA NPs.ResultsWe found that Au-MEA NPs exhibited better stability and permeation properties compared to conventional Au-CA NPs. Transcutaneously administered Au-MEA NPs exerted potent therapeutic efficacy against both rosacea-like and psoriasiform skin dermatitis in vivo without overt signs of toxicity. Mechanistically, Au-MEA NPs reduced the production of pro-inflammatory mediators in keratinocytes by promoting SOD activity and inhibiting the activity of MMP9.ConclusionAu-MEA NPs have the potential to be a topical nanomedicine for the effective and safe treatment of inflammatory skin diseases.

Analysis of dynamic response and impact resistance of corrugated plate-reinforced concrete under simulated rockfall

In this study, corrugated plate material is used as the internal mold for the reinforced concrete structure, proposing a combined shelter structure designed to protect against rockfall hazards in mountainous areas. The research focuses on the impact of low-velocity rockfall (below 150 km/h) directly hitting both the reinforced concrete structure and the corrugated plate and reinforced concrete combined shelter structure. The accuracy of the numerical simulation results is validated through comparative analysis with indoor model experiments. Further investigation reveals the impact resistance and failure characteristics of RC (Reinforced Concrete) structures, CPRC(D) (Corrugated plate double-layer reinforced concrete composite structure) structures and CPRC(S)（Corrugated plate single-layer reinforced concrete composite structure）, with the residual resistance index (RRI) introduced for the quantitative analysis of the residual load-bearing capacity of the protective structures post-impact. The results indicate that the shape of impact craters and the maximum impact force obtained through numerical simulations closely match the experimental findings, demonstrating the validity of the simulation parameters. Under the same impact energy, the maximum peak stress at various points in the CPRC structure is reduced by more than 50 % compared to the RC structure. Damage to the RC structure under rockfall impact is primarily characterized by central penetration failure and extensive development of diagonal cracks. In contrast, the CPRC structure effectively suppresses penetration, dent deformation, and crack propagation, significantly reducing the volume of concrete damage and the proportion of rebar damage, with the residual resistance index consistently remaining above 0.27.The corrugated plate and reinforced concrete combined structure outperforms the reinforced concrete structure in several impact resistance factors, including maximum impact force, effective stress extremes, structural damage, and penetration depth. Additionally, after reinforcement with corrugated plates, the CPRC structure maintains a high level of impact resistance in most scenarios, even when the lower layer of rebar is eliminated, providing a theoretical basis and preliminary feasibility proof for the lightweight modification of the structure.

A linear shaped charge cutting model for brittle flat plates

The dynamic response and damage fracture of brittle materials under explosive cutting have always been important research issues in the fields of military, aerospace, and other engineering fields. In this paper, a linear shaped charge cutting model for explosive cutting of brittle materials is proposed. This model suggests that explosive cutting is caused by the combined effects of jet penetration, spallation, and impact fracture. Theoretical calculation models for jet penetration, spallation, and impact fracture were constructed, and the concept of impact strength was introduced to establish dynamic mechanical performance parameters for brittle materials. A calculation program for explosive cutting of brittle materials was developed using the Python language, which can calculate the jet penetration depth, spallation thickness, and impact fracture thickness by inputting parameters such as the size and mechanical properties of the linear shaped charge and target plate, and determine whether the target plate can be successfully cut. Subsequently, a series of explosion cutting experiments and numerical simulations for brittle target plates were conducted to verify the accuracy of the calculation program. The results indicate a high degree of consistency between simulation, experimentation, and program calculation results. This work can provide guidance and promotion for the design and application of explosive energy harvesting cutters.

Market Penetration Strategy by Increasing Firm Competitiveness

To achieve successful market penetration, businesses must navigate complexities related to culture, legal frameworks, economic conditions, and competition. Businesses must decide whether to standardize their marketing strategies across different markets or adapt them to suit unique market characteristics. Competition is the ability to perform better, and faster. In facing competition, companies need to determine the right strategy, because in general companies are trying to survive, grow and develop. The purpose of the Market Penetration Strategy research by Increasing Company Competitiveness can include several aspects, namely, Assessing the company's strengths and weaknesses. Conducting market analysis to understand existing opportunities and challenges, including consumer preferences and behavior, and market trends and Developping an effective Market Penetration Strategy to increase market penetration, such as products, improving customer service, or competitive pricing strategies. This study uses a descriptive qualitative method to find out how PT. AJS Bumiputera markets its products, using market penetration to increase competitiveness, or to find out what the biggest challenges are in its market penetration strategy. This study uses a qualitative method as one of the methodologies in research that does not yet have a standard definition and is generally agreed upon for use. From the results of the study it is known that PT. Bumiputera Sharia Life Insurance, using market penetration through digital platforms such as social media, company websites, and online advertising campaigns to reach a wider audience. Organizing events, seminars, or workshops, related to finance or health. Providing education about the benefits of insurance products to the public, conducting direct promotions through telemarketing, or face-to-face marketing to introduce products directly.

Coupling algorithm of cavity expansion theory and finite element for penetrating reinforced concrete

Aiming at the dynamic problem of projectile penetrating reinforced concrete, this paper creatively proposes a coupling algorithm combining cavity expansion theory and the finite element method. This approach effectively resolves the problem of low efficiency in finite element simulations while ensuring computational accuracy. In this study, based on the cavity expansion theory, we have redeveloped the display dynamics software. Radial stress in the concrete is applied to the warhead surface in the normal direction, and the interaction between the projectile and the steel bar is simulated using the finite element contact algorithm. A coupling algorithm has been developed that can stably and quickly simulate the penetration of reinforced concrete by a projectile. The study indicates that the implementation of the coupling algorithm primarily includes four steps: model establishment and meshing, stress load program design, load application, and initial condition setting. Through verification and analysis, the coupling algorithm presented in this paper is demonstrated to effectively compute the dynamic response of a projectile during penetration. It exhibits superior computational stability and speed compared to the finite element method, and shows minimal sensitivity to grid size. When applied to numerical models with small meshes, it achieves both high precision and rapid computation. The coupling algorithm program design proposed in this paper can be implemented in any display dynamics software, offering a robust approach for engineers and researchers to predict projectile penetration effects. Furthermore, it provides a rapid assessment method for the anti-penetration performance of reinforced concrete structures.

Switching to Low Neurotoxic Antiretrovirals to Improve Neurocognition Among People Living With HIV-1-Associated Neurocognitive Disorder: The MARAND-X Randomized Clinical Trial

Background: The pathogenesis of HIV-associated neurocognitive (NC) impairment is multifactorial, and antiretroviral (ARV) neurotoxicity may contribute. However, interventional pharmacological studies are limited. Methods: Single-blind, randomized (1:1), controlled trial to assess the change of NC performance (Global Deficit Score, GDS, and domain scores) in PLWH with NC impairment randomized to continue their standard of care treatment or to switch to a less neurotoxic ARV regimen: darunavir/cobicistat, maraviroc, emtricitabine (MARAND-X). Participants had plasma and cerebrospinal fluid HIV RNA< 50 copies/mL, R5-tropic HIV, and were on ARV regimens that did not include efavirenz and darunavir. The change of resting-state electroencephalography was also evaluated. The outcomes were assessed at week 24 of the intervention through tests for longitudinal paired data and mixed-effect models. Results: Thirty-eight participants were enrolled and 28 completed the follow-up. Global Deficit Score improved over time but with no difference between arms in longitudinal adjusted models. Perceptual functions improved in the MARAND-X, while long-term memory improved only in participants within the MARAND-X for whom the central nervous system penetration-effectiveness (CNS penetration effectiveness) score increased by ≥3. No significant changes in resting-state electroencephalography were observed. Conclusions: In this small but well-controlled study, the use of less neurotoxic ARV showed no major beneficial effect over an unchanged regimen. The beneficial effects on the memory domain of increasing CNS penetration effectiveness score suggest that ARV neuropenetration may have a role in cognitive function.

Classification of Variants of Reduced Penetrance in High Penetrance Cancer Susceptibility Genes: Framework for Genetics Clinicians and Clinical Scientists by CanVIG-UK (Cancer Variant Interpretation Group-UK)

PurposeCurrent practice is to report and manage likely pathogenic/pathogenic variants in a given cancer susceptibility gene (CSG) as though having equivalent penetrance, despite increasing evidence of inter-variant variability in risk associations. Using existing variant interpretation approaches, largely based on full-penetrance models, variants where reduced penetrance is suspected may be classified inconsistently and/or as variants of uncertain significance (VUS). We aimed to develop a national consensus approach for such variants within the Cancer Variant Interpretation Group UK (CanVIG-UK) multidisciplinary network. MethodsA series of surveys and live polls were conducted during and between CanVIG-UK monthly meetings on various scenarios potentially indicating reduced penetrance. These informed the iterative development of a framework for the classification of variants of reduced penetrance by the CanVIG-UK Steering and Advisory Group (CStAG) working group. ResultsCanVIG-UK recommendations for amendment of the 2015 ACMG/AMP variant interpretation framework were developed for variants where (A) Active evidence suggests a reduced penetrance effect size (e.g. from case-control or segregation data) (B) Reduced penetrance effect is inferred from weaker/potentially-inconsistent observed data. ConclusionsCanVIG-UK propose a framework for the classification of variants of reduced penetrance in high-penetrance genes. These principles, whilst developed for CSGs, are potentially applicable to other clinical contexts.

Therapeutic targeting of senescent cells in the CNS.

Senescent cells accumulate throughout the body with advanced age, diseases and chronic conditions. They negatively impact health and function of multiple systems, including the central nervous system (CNS). Therapies that target senescent cells, broadly referred to as senotherapeutics, recently emerged as potentially important treatment strategies for the CNS. Promising therapeutic approaches involve clearing senescent cells by disarming their pro-survival pathways with 'senolytics'; or dampening their toxic senescence-associated secretory phenotype (SASP) using 'senomorphics'. Following the pioneering discovery of first-generation senolytics dasatinib and quercetin, dozens of additional therapies have been identified, and several promising targets are under investigation. Although potentially transformative, senotherapies are still in early stages and require thorough testing to ensure reliable target engagement, specificity, safety and efficacy. The limited brain penetrance and potential toxic side effects of CNS-acting senotherapeutics pose challenges for drug development and translation to the clinic. This Review assesses the potential impact of senotherapeutics for neurological conditions by summarizing preclinical evidence, innovative methods for target and biomarker identification, academic and industry drug development pipelines and progress in clinical trials.

Excessive autophagy-inducing and highly penetrable biomineralized bacteria for multimodal imaging-guided and mild hyperthermia-enhanced immunogenic cell death

The tumor microenvironment, characterized by hypoxia, supports the efficacy of anaerobic bacteria like attenuated S. typhimurium in cancer therapies. These bacteria target and penetrate deep tumor regions, significantly reducing tumor size but often lead to tumor regrowth due to limited long-term efficacy. To enhance the therapeutic impact, a novel biohybrid system, S@UIL, has been developed by coating S. typhimurium with a zirconium-based nanoscale metal–organic framework (UiO-66-NH2) loaded with indocyanine green (ICG) and luteolin (LUT). This system maintains the bacteria’s tumor-targeting ability while increasing the penetration and therapeutic effectiveness through excessive autophagy and mild hyperthermia. In a subcutaneous colon cancer model, the integration of LUT and ICG promotes autophagic cell death and photothermal sensitization, leading to the release of damage-associated molecular patterns (DAMPs). These DAMPs activate immune responses through dendritic cells and T-cells, enhancing immunogenic cell death (ICD) and potentially reducing immune evasion by tumors. This single-administration approach also integrates multimodal imaging capabilities, providing a promising strategy for improved tumor ICD induction and cancer progression inhibition.

Условия появления интенсивных потоков энергичных электронов на L<1.2, связанные с солнечной активностью и параметрами солнечного ветра

We present the results of a statistical study of transient enhancements of electrons with energies >30 keV at low drift shells in the quasi-trapped region (forbidden zone) at the geomagnetic equator. Using data from low-altitude NOAA/POES and MetOp satellites, we have compiled a catalog of events with forbidden energetic electron (FEE) enhancements for the period from 1998 to 2023. Statistical analysis of FEE events has revealed solar-cyclic, as well as seasonal and diurnal variations in the occurrence of FEE enhancements. We have examined the correlation of the annual frequency of FEE events with solar activity, solar wind parameters, and geomagnetic activity. Strong correlations have been found with the F10.7 index of solar activity (radio emission flux) as well as with the Alfvén Mach number (solar wind parameter). An interpretation of the obtained results is proposed which is based on the mechanism of electrical drift and radial transport of electrons from Earth’s inner radiation belt to the quasi-trapped region (L<1.2). The key factor for the operation of the mechanism is the effective penetration of the electric field to low latitudes when a significant difference in the conductivity of the high-latitude ionosphere occurs in the illuminated and unilluminated sectors of local time under conditions of weakening auroral activity.

Conditions for the occurrence of intense fluxes of energetic electrons at L<1.2 associated with solar activity and solar wind parameters

We present the results of a statistical study of transient enhancements of electrons with energies >30 keV at low drift shells in the quasi-trapped region (forbidden zone) at the geomagnetic equator. Using data from low-altitude NOAA/POES and MetOp satellites, we have compiled a catalog of events with forbidden energetic electron (FEE) enhancements for the period from 1998 to 2023. Statistical analysis of FEE events has revealed solar-cyclic, as well as seasonal and diurnal variations in the occurrence of FEE enhancements. We have examined the correlation of the annual frequency of FEE events with solar activity, solar wind parameters, and geomagnetic activity. Strong correlations have been found with the F10.7 index of solar activity (radio emission flux) as well as with the Alfvén Mach number (solar wind parameter). An interpretation of the obtained results is proposed which is based on the mechanism of electrical drift and radial transport of electrons from Earth’s inner radiation belt to the quasi-trapped region (L<1.2). The key factor for the operation of the mechanism is the effective penetration of the electric field to low latitudes when a significant difference in the conductivity of the high-latitude ionosphere occurs in the illuminated and unilluminated sectors of local time under conditions of weakening auroral activity.

Performance assessment of multi-source GNSS radio occultation from COSMIC-2, MetOp-B/C, FY-3D/E, Spire and PlanetiQ over China

Global Navigation Satellite System (GNSS) radio occultation (RO) is one of the most crucial observations in atmospheric and climate science. GNSS RO globally produces accurate and long-term stable vertical profiles for essential climate variables with high vertical resolution in all weather conditions. RO measurements offer global coverage but may be limited for specific regions. Currently, various RO satellite constellation programs have been developed by nations and companies, and the growing quantity of RO observations can contribute not only globally but also has the potential to benefit specific regions, such as China. To investigate the potential of RO observation in China, the performance of five operational RO measurements from COSMIC-2, MetOp-B/C, FY-3D/E, Spire and PlanetiQ on data coverage capabilities and quality are assessed by comparing with ERA5 and radiosonde over China. The results of data coverage showed that all RO missions can acquire extensive coverage over China with effective low-altitude penetration capability, whereas MetOp-B/C exhibits some gaps in local time coverage. The results of data quality confirmed that commercial Spire and PlanetiQ are comparable to those of national-led COSMIC-2, MetOp-B/C and FY3D/E, even though Spire exhibited a lower signal-to-noise ratio (SNR). The mean bending angle and refractivity relative differences of all RO measurements are within ±0.53/1.30 % and ± 0.54/0.28 % (with respect to ERA5/radiosonde) in the altitude range of 5 to 35 km, respectively, and the corresponding relative standard deviations (SD) are less than 2.20/6.99 % and 1.35/1.56 %, respectively. Mean temperature and specific humidity differences of all RO measurements are within ±0.18/0.22 K and ± 0.08/0.22 g/kg, respectively, from the near-surface to 12 km, with SD of less than 1.26/1.67 K and 0.84/0.91 g/kg. Among the five RO missions, FY-3D/E exhibits larger errors in refractivity, temperature and specific humidity. The RO profiles derived from GPS, GLONASS, BeiDou and Galileo show comparable quality at the altitudes below 35 km. These results can help users further understand the capabilities and performance of these RO observations and indicate the application potential of numerous RO profiles from multi-source RO measurements, which is anticipated to enhance numerical weather predictions for China.

Wireless Light‐Emitting Diode‐Driven Functional Microneedle Devices for Skin Cancer Therapy

AbstractPhotodynamic therapy, a noninvasive cancer treatment strategy, is a promising remedy for malignant skin cancers. However, treatment of skin cancer with this method requires sufficient photosensitizer molecules to permeate into cancer cells before illumination for effective activation to induce potent reactive oxygen species for eliminating cancer cells. However, transdermal drug delivery using conventional photosensitizers faces major challenges due to skin barriers, diminishing the effectiveness of drug penetration and therapeutic efficacies. To overcome these limitations, biocompatible, physiologically dissolvable, and optically activatable functional microneedle devices are applied for effective percutaneous penetration of drug molecules into solid tumors in a murine model. The proposed wireless light‐emitting diode light‐driven functional microneedle device that effectively induces apoptosis of cancer cells and disruption of the tumor area and can enhance in vitro, ex vivo, and in vivo drug‐delivery effectiveness for treating skin cancer. The design and strategy of the present functional microneedle devices can help shed light on future advanced cancer therapy.

Recombinant filaggrin-2 improves skin barrier function and attenuates ultraviolet B (UVB) irradiation-induced epidermal barrier disruption

The integrity of the skin barrier is essential for maintaining skin health, with the stratum corneum and filaggrin 2 (FLG-2) playing a key role. FLG-2 deficiency or mutation has been linked to diseases such as atopic dermatitis, while external stressors such as ultraviolet B (UVB) radiation further damage the epidermal barrier. This study investigated the effects of recombinant filaggrin (rFLG) on skin barrier function and UVB induced epidermal destruction. Cell experiments showed that 10 μg/mL of rFLG could increase the mobility of HaCaT cells from 20 % to 42 %, increase the epithelial resistance (TEER) value by about 2 times, and up-regulate the tight junction associated protein by about 2 times. In mouse models of UVB-induced epidermal barrier destruction, rFLG at concentrations of 0.5, 1, and 2 mg/mL showed effective cell uptake and skin penetration, alleviating erythema, and reducing skin thickness in mice by 1.5–3 times. Among them, 2 mg/mL of rFLG treatment restored the expression of tight junction proteins (LOR, ZO-1, and caspase-14), reduced collagen degradation, and reduced oxidative stress by normalizing serum hydroxyproline and superoxide dismutase levels. In addition, 2 mg/mL of rFLG inhibited UVB-induced upregulation of matrix metalloproteinases (MMP-3 and MMP-9) and reduced pro-inflammatory factors (IL-10, IL-1α, IL-6, and TNF-α) and apoptotic markers (P38, Bax, and Bcl-2) to normal levels. These findings suggested that rFLG effectively enhanced skin barrier integrity and mitigated UVB-induced epidermal barrier destruction, highlighting its potential as a therapeutic agent for diseases associated with skin barrier dysfunction.

Ionic Liquid-Based Grapeseed Oil Emulsion for Enhanced Anti-Wrinkle Treatment.

To address the poor efficacy and percutaneous penetration of grape seed oil, ionic liquids and nanotechnology were combined to prepare a grape seed oil emulsion. A novel Menthol-CoQ10 ionic liquid and ionic liquid based grapeseed oil emulsion were prepared and confirmed. The average size of the grapeseed oil emulsion was 218 nm, and its zeta potential was -33.5 mV. The ionic liquid-based grape seed oil emulsion exhibited a transdermal penetration effect 4.63-fold higher than that of ordinary grape seed oil emulsion. Ionic liquid also displayed enhanced efficiency both in vitro and in vivo. It significantly inhibited the production of DPPH free radicals and tyrosinase, inhibited melanin and matrix metalloproteinase-1 (MMP-1) produced by cells, and promoted type I collagen expression in fibroblasts. After 28 days of continuous use, the grapeseed oil emulsion improved the water content of the stratum corneum and the rate of transepidermal water loss, enhanced the firmness and elasticity of the skin, and significantly improved the total number and length of under-eye lines, tail lines, nasolabial folds, and marionette lines on the face. Menthol-CoQ10 ionic liquid is a promising functional excipient for both transdermal delivery increase and efficient enhancement. Ionic liquid and nanotechnology for grape seed oil facial mask displayed significantly enhanced efficacy and permeability.

Ionic liquid combined with cationic liposome co-delivers microphthalmia-associated transcription factor small interfering RNA to regulate melanogenesis

Suppressing allele-specific genes using small interfering RNAs (siRNAs) can effectively whiten skin by influencing cellular gene and protein expression. Topical delivery of siRNA is a promising alternative to injections for RNA interference. However, the barrier function of the skin hinders the effective penetration of siRNA. Here, we report, a novel approach to achieve the transdermal delivery of effective siRNA doses using a complementary synergistic strategy of an ionic liquid (IL) and cationic liposome (CL). Microphthalmia-associated transcription factor (MITF) siRNA molecules were formed through electrostatic adsorption of the IL and CL to form positively charged nanocomposites, which were named IL-CL/p-siM. IL-CL/p-siM has a particle size of 171.47 nm, ζ-potential of 29.94 mV, high encapsulation rate of 92.11 %, and pH-sensitive release properties. In vitro studies on porcine skin confirmed the additive/synergistic effect of this strategy in enhancing epidermal and dermal penetration. This combination enabled superior transfection efficiency and cell viability while inhibiting melanin synthesis in skin melanocytes by downregulating the expression of genes downstream of MITF, namely tyrosinase-related protein-1, tyrosinase, and tyrosinase-related protein-2, which are associated with the melanocortin 1 receptor. We also conducted clinical studies that demonstrated its potential in treating melasma and its anti-melanotic efficacy. To summarize, IL-CL/p-siM represents a simple, personalized, and scalable platform for effective local delivery of siRNA to treat skin complications.

Dynamic analysis and experimental study of Down-the-Hole hammer based on DEM-MBD method

Pneumatic DTH(Down-The-Hole) hammer impact-rotary-compaction drilling is a well-established technology widely used in foundation engineering. This technique combines the advantages of impact rotary drilling and compaction drilling, making its working mechanism and fracturing process more complex. First, the dynamic differential equations for the DTH hammer piston and the coupled longitudinal vibration partial differential control equations for the DTH hammer and the soil stratum were established. The dynamic working characteristic curve of the piston was then obtained using the finite difference method(FDM).Subsequently, the DEM-MBD method was employed to compare the drilling efficiency of three types of drill bits—single-helix, multi-helix, and stepped bits—across three diameter specifications (Φ108, Φ135, Φ216) in three distinct strata: clay, pebble, and silty sand. The drilling efficiency of the multi-spiral bit was on average 11% and 21% higher than that of the single-spiral and stepped bits. From a micromechanical perspective, the shear failure effect of the drill bit on the soil was analyzed. The axial force of the drill bit (Z-axis) remained essentially consistent. Using the Y-axis as an example, 6% of the shear force for the single-helix bit falls within the 300–500N range, while 31% of the shear force for the multi-helix bit lies within the same range. Field tests demonstrated that the drilling efficiency and penetration effects simulated using the DEM-MBD method aligned with the actual test results, confirming the accuracy of this method.

Spatial‐coupled Ampere‐level Electrochemical Propylene Epoxidation over RuO2/Ti Hollow‐fiber Penetration Electrodes

AbstractThe electrochemical propylene epoxidation reaction (PER) provides a promising route for ecofriendly propylene oxide (PO) production, instantly generating active halogen/oxygen species to alleviate chloride contamination inherent in traditional PER. However, the complex processes and unsatisfactory PO yield for current electrochemical PER falls short of meeting industrial application requirements. Herein, a spatial‐coupling strategy over RuO2/Ti hollow‐fiber penetration electrode (HPE) is adopted to facilitate efficient PO production, significantly improving PER performance to ampere level (achieving over 80 % PO faradaic efficiency and a maximum PO current density of 859 mA cm−2). The synergetic combination of the penetration effect of HPE and the spatial‐coupled reaction sequence, enables the realization of ampere‐level PO production with high specificity, exhibiting significant potentials for economically viable PER applications.

Spatial-coupled Ampere-level Electrochemical Propylene Epoxidation over RuO2/Ti Hollow-fiber Penetration Electrodes.

The electrochemical propylene epoxidation reaction (PER) provides a promising route for ecofriendly propylene oxide (PO) production, instantly generating active halogen/oxygen species to alleviate chloride contamination inherent in traditional PER. However, the complex processes and unsatisfactory PO yield for current electrochemical PER falls short of meeting industrial application requirements. Herein, a spatial-coupling strategy over RuO2/Ti hollow-fiber penetration electrode (HPE) is adopted to facilitate efficient PO production, significantly improving PER performance to ampere level (achieving over 80 % PO faradaic efficiency and a maximum PO current density of 859 mA cm-2). The synergetic combination of the penetration effect of HPE and the spatial-coupled reaction sequence, enables the realization of ampere-level PO production with high specificity, exhibiting significant potentials for economically viable PER applications.