You have accessJournal of UrologyProstate Cancer: Localized: Surgical Therapy V1 Apr 2018PD38-02 FOUR-POINT PERITONEAL FLAP FIXATION IN PREVENTING LYMPHOCELE FORMATION FOLLOWING RADICAL PROSTATECTOMY Jens Uwe Stolzenburg, Vinodh Kumar Adithyaa Arthanareeswaran, Anja Dietel, Toni Franz, Evangelos Liatsikos, Iason Kyriazis, Roman Ganzer, Abinaya Ravichandran Chandra, and Hoang Minh Do Jens Uwe StolzenburgJens Uwe Stolzenburg More articles by this author , Vinodh Kumar Adithyaa ArthanareeswaranVinodh Kumar Adithyaa Arthanareeswaran More articles by this author , Anja DietelAnja Dietel More articles by this author , Toni FranzToni Franz More articles by this author , Evangelos LiatsikosEvangelos Liatsikos More articles by this author , Iason KyriazisIason Kyriazis More articles by this author , Roman GanzerRoman Ganzer More articles by this author , Abinaya Ravichandran ChandraAbinaya Ravichandran Chandra More articles by this author , and Hoang Minh DoHoang Minh Do More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2018.02.1749AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Symptomatic lymphocele following laparoscopic/robot assisted radical prostatectomy (RP) and concomitant bilateral extended pelvic lymph node dissection (PLND) procedure has a significant impact on the postoperative recovery and may sometime require surgical intervention. Various strategies have been tested until now to prevent postoperative lymphocele without considerable success. We report the utilization of four-point peritoneal flap fixation (4PPFF) during RP in decreasing the lymphocele formation following PLND. METHODS 4PPFF was performed by suturing the cut end of the ventral parietal peritoneum at four points (to anterior and lateral pelvic side wall on both sides) following PLND such that the peritoneal surface is exposed to the iliac vessels and obturator fossa. Between April 2010 - May 2017, 1358 patients underwent RP with concomitant bilateral extended PLND procedure. From this cohort 193 patients who had undergone PNLD with four-point PF were matched in a 1:1 ratio to patients who underwent PLND without 4PPF with respect to age, body mass index, initial PSA and number of lymph nodes removed. All patients underwent ultrasound on postoperative days 2, 6, 28 and 90 to test for the presence of any lymphoceles. Statistical analysis was performed using Medcalc statistical software (Ver. 17.9, Ostend, Belgium). For univariate analysis, chi-square test and Annova were used appropriately. Statistical significance was set at a p value less than 0.05, and all reported p values were two-sided. RESULTS There was no significant difference between the two groups with respect to intraoperative blood loss, positive surgical margin rate, Gleason score, clinical stage and number of positive cores. Incidence of asymptomatic lymphocele was observed in 4 (2.07%) patients in the 4PPFF group compared to 16 (8.3%) patients without 4PPFF (p=0.0058). Similarly, significant difference was observed in the incidence of symptomatic lymphocele; 2 (1.03%) patients in 4PPFF group vs 9 (4.6%) patients without 4PPF (p=0.0322). There was no difference in other complication rates between the two groups. CONCLUSIONS 4PPFF is a safe and effective procedure in preventing lymphocele formation in patients undergoing RP with PLND. The increased exposure of peritoneal surface to the PLND raw area following this procedure may aid in increased absorption of the accumulating lymph fluid from the PLND raw area. Further prospective randomized multicenter studies are warranted to confirm our observations. © 2018FiguresReferencesRelatedDetails Volume 199Issue 4SApril 2018Page: e736 Advertisement Copyright & Permissions© 2018MetricsAuthor Information Jens Uwe Stolzenburg More articles by this author Vinodh Kumar Adithyaa Arthanareeswaran More articles by this author Anja Dietel More articles by this author Toni Franz More articles by this author Evangelos Liatsikos More articles by this author Iason Kyriazis More articles by this author Roman Ganzer More articles by this author Abinaya Ravichandran Chandra More articles by this author Hoang Minh Do More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...
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