Bladder exstrophy is an uncommon urologic condition believed to be present in one in 10,000 to 50,000 live births1,2. Patients with this condition often require extensive treatment, including multiple surgeries early in life. Identification of pelvic ring disruption in this patient population is challenging and may be complicated by anterior pelvic deficiency, pubic diastasis, external rotation of innominate bones, and previous pelvic osteotomies1. Once identified, treatment of pelvic disruption in patients with bladder exstrophy may be complicated by comorbidities and osteotomy-related pelvic deformity. We present a patient with bladder exstrophy and an anterior-posterior compression type-III (APC-III) pelvic injury sustained from a high-energy trauma. To the best of our knowledge, this is the first case report of its kind in the English-language literature. The patient was informed that data concerning the case would be submitted for publication, and he provided consent. A thirty-year-old man with a history of bladder exstrophy, hypospadias, and bladder cancer presented to our institution after a motorcycle accident. The patient, who had been wearing a helmet, sustained loss of consciousness. The previous surgical history included neobladder creation at age three and multiple other unknown procedures to address the exstrophy, including a pelvic osteotomy. Medical records prior to this injury were not available. He had a left APC-III pelvic injury, a neobladder rupture, a perineal laceration, an open fracture of the right tibia, and a closed fracture of the right medial malleolus (Fig. 1 and Figs. 2-A through 2-D). Initially, he was hemodynamically unstable and required four units of packed red blood cells, two units of fresh-frozen plasma, ten units of platelets, and 4 L of crystalloid to maintain a systolic blood pressure of 90-100 mm Hg. The initial computed tomography (CT) scan of the abdomen and pelvis demonstrated contrast extravasation around …