Peg-shaped Lateral Incisors Research Articles

Evaluation of Developmental Dental Anomalies in an Adult Dentate Iraqi Sub-Population of Sulaimani City by Using Panoramic Radiographs

Objective: The present study attempts to evaluate the prevalence of developmental dental anomalies in patients aged 18 years and over by using panoramic radiographs among the Kurdish subpopulation in Sulaimani city.
 Methods: Seven hundred and ninety-four OPGs between 2010 and 2022 were evaluated retrospectively in this study. Using panoramicradiography to evaluate the frequency of dental anomalies in shape, structure, number, and size.
 Results: The prevalence of dental anomalies diagnosed by panoramic radiographs was 26.6% among the sample. Anomalies of shapewere the most common abnormalities, followed by number, size, and structure. The most common anomaly seen in this study wasdilaceration (18.52%), followed by hypodontia and microdontia (both 16.67%), taurodontism, and macrodontia (16.05.%). Lessfrequent sub-types were amelogenesis imperfecta, peg-shaped lateral incisors and ghost teeth, accounting for 0.62%.
 Conclusions: Tooth shape anomalies were the most prevalent forms of developmental dental defects among the Kurdish subpopulation in Sulaimani city. Dilaceration, hypodontia, microdontia and taurodontism were the most prevalent categories ofabnormalities. The study confirmed that racial variables play a role in the incidence of dental anomalies. In addition, digital panoramicradiography is a beneficial method for the detection of dental abnormalities. Importantly, patient management and the treatment design are dependent on an early diagnosis.

Esthetic Rehabilitation of Congenitally Peg-Shaped Lateral Incisors Using the Injectable Composite Resin Technique: A Clinical Report

ABSTRACT This report details the esthetic dental rehabilitation of a patient with peg-shaped and malformed lateral incisors, conditions that stem from congenital anomalies in tooth formation, using the injectable composite resin technique (ICRT). The ICRT clinical workflow initiates with a smile analysis and precise shade matching, followed by the construction of a diagnostic wax-up crafted according to esthetic and functional guidelines. Subsequently, a mock-up is developed to ensure that the planned restorations fulfill the patient’s functional requirements and esthetic expectations. A transparent silicone index is employed to accurately transfer the patient-approved wax-up into the mouth, utilizing injectable flowable composite resin. This method enhances treatment predictability and ensures that the final direct restoration precisely reflects the approved design within a reasonable chairside timeframe.

Revamping the Peg Smile with Composites

Abstract Patient’s expectations for esthetic dentistry have risen in recent years. Having the perfect smile is becoming a goal, as celebrities and public figure’s appearances have undoubtedly improved as a result of smile correction. This case report is unique, as this type of restoration enhances smiles by a conservative and economic approach. The main clinical finding of the present case was smaller shape and size of medially inclined laterals when compared to other teeth, so the diagnosis was peg-shaped laterals, which are the most common but rare too dental form aberration that can distort the harmony of smile and affect patient psychology. Treatment options can vary depending on no prep or prep type of modification. Composites are of no preparation type of restoration, that can easily solve the esthetic issue of peg-shaped teeth, and boost up the patient satisfaction level for the treatment. The present case involves bilateral peg-shaped lateral incisors as a developmental anomaly treated with composites.

Delayed eruption of permanent maxillary first molars among Saudi children: A cross-sectional study

AimThis retrospective cross-sectional study aimed to determine the prevalence of delayed development and eruption of permanent maxillary first molars (U6) and associated dental anomalies in a sample of Saudi children. Material and methodsIn total, 10,232 panoramic radiographs from 9,672 patients were screened for delayed U6 eruption. Radiographs showing delayed U6 eruption were further examined for associated dental anomalies. The dental age of participants was estimated using The London Atlas of Human Tooth Development and Eruption. ResultTwenty cases of delayed U6 eruption were found, with a prevalence of 0.2%. Of these patients, 3 and 17 were males and females, respectively; 9 and 11 cases were unilateral and bilateral, respectively. Congenital absence of the adjacent permanent second molar was observed in 8 cases, and the congenital absence of permanent teeth, except the adjacent second permanent molar and third molar, was observed in 6 cases. Peg-shaped lateral incisors were observed in 6 females. No significant associations were observed between delayed U6 eruption and dental anomalies. Overall, the average delayed U6 eruption was 2.3 years for males and 2.8 years for females. ConclusionAmong a sample of Saudi children, the prevalence of delayed U6 eruption was 1 in 483 (0.2%) and five times higher in females. No significant associations were found between delayed U6 eruption and dental anomalies; however, congenital absence of the adjacent permanent second molar was observed in 40% of cases.

Features of Dental Anomaly Patterns in Finnish children as seen in panoramic radiographs at the late mixed stage

Objective To describe the prevalence of the developmental abnormalities involved in Dental Anomaly Patterns (DAP) and investigate their co-occurrence in an age cohort of children with late mixed dentition. Material and Methods Retrospective, register-based study focused on 1315 panoramic radiographs of children aged 8.5-10.5 years. The features examined were absent teeth, peg-shaped maxillary lateral incisor, delayed dental age, infraocclusion of primary molars, transposition and distal angulation of unerupted mandibular second premolar. Results Feature involved in DAP was detected in 29.8% of the children, most common being infraocclusion of primary molars (17.5%), followed by absent teeth (8.4%), delayed dental age (7.6%), distal angulation of unerupted mandibular second premolar (7.3%), peg-shaped maxillary lateral incisor (2.4%) and transposition (0.5%). Two DAP features occurred together in 4.7% of children, while three occurred in 0.7%. Infraocclusion (p=.040) and absent teeth (p=.001) occurred more commonly in girls. Phenotypic variations in maxillary lateral incisor more often occurred together (p=.004). Absent teeth, peg-shaped maxillary lateral incisor and delayed dental age more often occurred together (p<.01) as did transposition and absent teeth (p=.016). Conclusion Almost third of the children had dental developmental abnormalities involved in DAP. Absent teeth, peg-shaped lateral incisors and delayed dental age more often occurred together.

CAD-CAM Designed Ceramic Veneer for the Restoration of Peg-shaped Lateral Incisor: Case Report

Peg shaped lateral incisors are considered to be the most common discrepancy concerning tooth size. This results in reduced size of the tooth, anterior diastema, and most often an unpresentable smile. Now a days, the concepts of Adhesive Dentistry and wider use of ceramic veneers have allowed all ceramic restorations to be more acceptable in terms of function and esthetics as well as establishing a good smile harmony. The aim of the clinical report presented, is to demonstrate a conservative approach of treatment so as to improve an esthetically disharmonious smile resulting from a unilateral peg-shaped lateral incisor. Here the authors present a case of 33 years old Saudi patient, who sought treatment for solving his esthetically disharmonious smile. Digital Impression guides were utilized for planning and fabricating Lithium Disilicate veneers. This was done to restore the size, morphology, function, as well as the esthetics of upper lateral incisors including the overall smile of the patient. The veneers using Lithium disilicate provided the harmonization of smile of the patient. It further resulted in recovering of the tooth size including its shape as well as anatomical characteristics.

Three-dimensional digital evaluation of tooth symmetry and volume in patients with missing and peg-shaped maxillary lateral incisors

This study aimed to evaluate the 3-dimensional tooth crown symmetry and the crown volumes of maxillary and mandibular teeth in patients with unilateral or bilateral missing or peg-shaped maxillary lateral incisors. Six groups were established for the possible clinical variations in patients with unilateral missing or peg-shaped maxillary lateral incisors, bilateral presence of these tooth anomalies, and a control group (CG) with normal lateral incisors. The study was conducted on digital dental models of 132 patients. The morphologic symmetry of the antimere teeth was investigated using 3-dimensional deviation analysis. Volumes of contralateral teeth were compared within and among groups for the maxilla and mandible. Furthermore, volumes of teeth were compared in missing and peg-shaped quadrants and quadrants of CG. Intergroup differences were tested using one-way analysis of variance and Kruskal-Wallis tests, whereas paired t and Wilcoxon tests were used for parametric and nonparametric variables, respectively, for intragroup comparisons. Significant deviations in symmetry of antimere teeth were not detected (P>0.05). The volumes of mandibular central and lateral incisors in missing or peg-shaped lateral incisor groups were smaller than in the CG (P<0.05). Per quadrant analysis, volumes of the maxillary central incisor and mandibular central incisors, canines, and first molars in quadrants with missing or peg-shaped lateral incisors were smaller than in the control quadrants (P<0.05). Neither unilateral nor bilateral presence of missing or peg-shaped maxillary lateral incisors affected the morphologic symmetry of antimere teeth but did affect tooth volume, especially in the mandibular arch.

Prevalence of Dental Anomalies in Orthodontic Patients.

AimThe aim of this retrospective study was to determine the frequency of hypodontia, hyperdontia, invagination, impaction, dilacerations, peg-shaped lateral incisors, taurodontism and short or blunt and narrow or pipette-shaped roots in Croatian orthodontic patients.Material and methods506 orthopantomographs and study casts from 12-16 year-old orthodontic patients treated at the Department of Orthodontics, School of Dental Medicine University of Zagreb were analyzed.ResultsAt least one dental anomaly was present in 24.1% of patients, and more than anomaly in 1.2% of them. The frequency was not significantly different between genders. Hypodontia was the most frequent anomaly with the incidence of 7.5%, followed by teeth impaction with the incidence of 6.3%.ConclusionThe distribution and the prevalence of anomalies were similar to those described in the general Croatian population.

Pattern and prevalence of dental anomalies among a paediatric population in Lagos, Nigeria.

Dental anomalies are craniofacial abnormalities in the size, structure or number of the teeth. This study was conducted to assess the prevalence of dental anomalies among children aged 0-16 years attending the Paediatric Dental Clinic at the Lagos University Teaching Hospital, Lagos, Nigeria. A cross-sectional design was used and data were obtained from the dental records of the Dental Clinic from January 2014 to August 2019 by two calibrated examiners, who are co-authors of the manuscript. To test for statistical differences, Chi-squared test was utilised for the categorical variables. The prevalence of the different dental anomalies was estimated and presented with frequencies. P < 0.05 was considered statistically significant. Among the 6175 patients' dental records reviewed, 50.85% (n = 3150) were male and the highest proportion of 45.4% (n = 2807) were aged between 6 and 10 years, with a mean age of 8.62 ± 3.85 years. A total of 1090 (17.52%) had dental anomalies; 465 (7.53) anomalies were in the maxilla, 263 (4.6) were in the mandible while 360 (5.83) were in both. The most common anomaly was hypoplasia 550 (9.06%), followed by retained primary tooth 546 (8.84%) and hypodontia 84 (1.36%). Dentinogenesis imperfecta 1 (0.02) and transposition 1 (0.02) were the least prevalent anomalies. Retained primary teeth (5.8%) and the cusp of Carabelli (0.4%) were slightly more prevalent among males. However, females had a higher prevalence of natal/neonatal teeth (0.4%), fusion/germination (0.4%), hypodontia (1.5%) and peg-shaped lateral incisors (0.9%). Dental anomalies' prevalence in this study was 17.52%, with a higher occurrence of anomalies in the maxilla. Hypoplasia was the most prevalent anomaly, after which was retained primary tooth, then hypodontia. Prompt diagnosis and preventive interventions are crucial for the appropriate management of these dental anomalies.

Craniofacial and Oral Manifestations of Non-Syndromic Hypodontia: A Review

AbstractPatients with hypodontia appear to have a different craniofacial morphology as compared with controls. They tend to have more class III skeletal pattern and retroclined upper and lower soft tissue lips as a consequence of retroclined upper and lower incisors. These features are more pronounced as the severity of the hypodontia increases. In addition to changes in craniofacial and soft tissue morphology, various dental anomalies are commonly associated with hypodontia such as microdontia of the remaining dentition, anomalies in tooth shape, particularly peg-shaped upper lateral incisors, smaller root dimensions of some of the permanent teeth, and decreased maxillary and mandibular dental arch widths and lengths measurements. Other dental anomalies which are seen in association with hypodontia are taurodontism of molars, retained deciduous molars, delayed development of the permanent teeth, distoangulation of the mandibular second premolar, and infraocclusion of the deciduous molars.

Invisalign System as a Treatment of a Skeletal Open Bite: A Case Report With a 5-Year Follow-up

Background: Orthodontic treatments of skeletal open bite are among the most challenging and at high relapse. Available therapies vary from behaviour-modifying appliances in growing patients to surgical approach in adults. Recently, clear aligners, such as Invisalign®, have also been proposed as a treatment modality, to be used alone or in combination with temporary anchorage devices. Case report: A 19-year-old female presented with 3-mm anterior open bite, peg-shaped upper lateral incisors, incorrect tongue posture at rest and during function. Due to aesthetic request, an orthodontic camouflage with Invisalign® was carried out for 17½ months, along with myofunctional therapy and composite veneers on upper lateral incisors. During the first months of retention, intermaxillary vertical elastics were maintained at night-time as positive feedback to the tongue. A 5-year follow-up confirmed stability of the results. Conclusions: A system of clear aligners in combination with myofunctional therapy was effective in the treatment of a skeletal open bite malocclusion, with stability at 5 years. The closure of the anterior open bite was obtained through a combination of lower molar intrusion, incisor extrusion and counterclockwise rotation of the mandible. In selected cases of optimal compliance, Invisalign® may constitute a feasible treatment option in management of open bite in non-growing patients.

CLOSURE OF MIDLINE DIASTEMA BY DIRECT COMPOSITE RESIN BUILD-UP USING PUTTY INDEX- A CASEREPORT

A common aesthetic concern among patient is maxillary anterior space or diastema. Labial frenulum, microdontia, mesiodens, peg-shaped lateral incisors, agenesis, cysts, habits such as finger sucking, tongue thrusting, or lip sucking, dental malformations, genetics, proclinations, dental-skeletal discrepancies, and imperfect coalescence of the interdental septum are some of the causes of midline diastema. For diastema closure there are a variety of therapy options. Many novel therapies have been applied, ranging from restorative procedures to surgery (frenectomies) and orthodontics for closure of diastema or a combination of procedures to meet the aesthetic and functional needs of patient’saesthetic. Recent advancement in direct dental composite resin allows dentists to do minimally invasive cosmetic dentistry that is both conservative and time-consuming. In diastema cases, direct composite resins give the dentist and patient entire control over the restriction and the construction of a natural smile. The purpose of this study is to present a case report of aesthetic management using putty index of maxillary anterior space, which includes the midline.

Association between Third Molar Agenesis and Other Dental Anomalies

Introduction: Third molar teeth are the most common teeth with agenesis. The absence of this tooth also increases the probability of anomalies in other teeth by several times. Since panoramic radiography is used to diagnose and plan treatment in orthodontic patients, along with routine clinical examination, this study aimed to determine the prevalence of third molar agenesis and incidence of other associated anomalies in comparison to that reported for the non-agenesis group using panoramic radiographs. Materials and Methods: In this descriptive-analytical study, the pretreatment records of 562 patients were randomly collected. Out of these subjects, 538 patients were selected based on inclusion and exclusion criteria. The panoramic radiographic images of patients who did not have at least one third molar were assessed with regard to the presence of other dental anomalies, such as dental agenesis, hypodontia, hyperdontia, impacted canine, peg-shaped lateral incisors, ectopic eruption, microdontia, dilaceration, transposition, and transmigration. The prevalence of these anomalies was compared to that of a randomized control group selected from patients with the presence of each four third molars. Results: Out of 538 studied panoramic radiographs, overall, 13.7%, 13.5%, 13.4%, 5.9%, 2.7%, and 1.4% of them had at least one third molar agenesis, canine impaction, peg-shaped lateral incisors, missing teeth, transposition, and hyperdontia, respectively. The frequency rates of impaction and missing teeth were higher in the agenesis group (30% and 40.5%) than those reported for the control group (16% and 2.7%) (p >0.001), respectively. The presence or absence of other dental anomalies was not statistically significant between the two groups and two genders. In addition, the present study demonstrated that the probability of the presence of at least one type of other dental anomalies was higher in individuals with third molar agenesis in comparison to that reported for the control group (p >0.001). Conclusion: Among different types of dental anomalies in the studied population, the probability of impaction and missing teeth was higher in the third molar agenesis group than that of the control group. Furthermore, the prevalence of third molar agenesis was not different between the two genders.

Esthetic Rehabilitation of A Peg-Shaped Lateral Incisor with Ceramic Veneer: About A Case Report

Esthetic Rehabilitation of A Peg-Shaped Lateral Incisor with Ceramic Veneer: About A Case Report

Canine-premolar Transposition, Family Pedigree and Related Dental Anomalies

Maxillary canine-premolar transposition is a rare and complicated dental anomaly that needs specialconsideration by the orthodontist. The aim of the present study was to investigate the clinical features ofmaxillary canine-premolar transposition and report the family pedigree to determine the mode of inheritance.A cross-sectional study was performed on 39 patients having maxillary canine-premolar transposition inwhich both clinical and radiographic examination were performed. Moreover, 112 family members wereclinically examined looking for canine transposition. Variables such as location, sex and the presence ofhypodontia and peg-shaped lateral incisors were investigated. The study found that unilateral transposition(89.7%) was more common than bilateral occurrence (10.2%) affecting the left side (64.1%) more than theright side (35.9%). Females were affected more than males (74.4% and 25.6% respectively). Congenitallymissing teeth were reported in 12.8% and lower second premolar was the most commonly missing tooth.Peg-shaped maxillary lateral incisor was reported in 7.7% of the sample. Family pedigree confirmed thepresence of a history of transposition or ectopically positioned canine in 15.3% of the sample suggestingan autosomal dominant inheritance of the trait. In conclusion this study suggested an association betweengenetic factors and maxillary canine-premolar transposition. Further studies are required using genetictesting to confirm the findings of the present study.

An interdisciplinary approach to management of diastemas: A novel classification and a case report

Diastema between the teeth negatively affects the patients' smile, psychology and daily activities by creating a disharmony in the patients' face. The development of diastema has been attributed to several factors such as labial frenulum, microdontia, mesiodens, peg-shaped lateral incisors, agenesis, cysts, habits such as finger sucking, tongue thrusting, or lip sucking, dental malformations, genetics, proclinations, dental-skeletal discrepancies, and imperfect coalescence of interdental septum. Patients often present with complex problems that require a multidisciplinary treatment approach which includes determination of the aetiological factors, soft tissue morphology, occlusion, patient demands and aesthetic consideration to achieve satisfactory outcomes. Lack of current literature on classification of diastemas and multi-disciplinary approach of management led to the proposal of a new classification the ATAC (Anatomic and Therapeutic Classification) for management of the diastema. This case report highlights the use of the proposed classification for management of diastemas, requiring a perio-restorative intervention using a Chu's proportion gauge to achieve ideal aesthetics.

Sella Turcica Bridging and Tooth Agenesis in Children With Unilateral Cleft Lip and Palate.

To investigate differences in sella turcica size and bridging in children with unilateral cleft lip and palate (UCLP) with or without concomitant dental anomalies. A cross-sectional study was carried out looking at 56 children with nonsyndromic UCLP. Lateral cephalograms, taken before alveolar bone grafting, were used to assess sella turcica height, width, area, and bridging. Panoramic radiographs were used to evaluate the presence of dental anomalies in the cleft area including agenesis, supernumerary, and peg-shaped lateral incisors. Differences between sella turcica measurements in the presence or absence of dental anomalies were assessed using t tests. Differences between the prevalence of dental anomalies and sella turcica bridging were assessed using χ2 and Fisher exact tests. Multinomial logistic regression was used to investigate potential associations between sella measurements and dental anomalies. Twenty-six of the 56 children presented with agenesis of the cleft-side lateral incisor, while 7 had a supernumerary, and 19 had a peg-shaped lateral incisor. With regard to sella turcica bridging, 27 children had no calcification, 25 partial and 4 complete calcification. Children with agenesis of the cleft-side lateral incisor showed a shorter sella maximum height (P = .010) and a smaller area (P = .019). When looking at sella turcica bridging, 100% of children with complete calcification showed agenesis of the cleft-side lateral incisor, compared with 52% and 33% of children with partial calcification and no calcification, respectively (P = .034). Children with UCLP and sella turcica bridging are more likely to present with agenesis of the cleft-side maxillary lateral incisor.

Phenotypic and Genotypic Features of Thai Patients With Nonsyndromic Tooth Agenesis and WNT10A Variants.

Tooth agenesis is one of the most common orodental anomalies that demonstrate phenotypic and genotypic heterogeneity with a prevalence of 2.5%–7%. Mutations in WNT10A have been proposed to be the most common cause of nonsyndromic tooth agenesis (NSTA). The aim of this study was to characterize the dental features and genetic variants of NSTA in a Thai population. We recruited 13 unrelated patients with NSTA who attended the Faculty of Dentistry, Chulalongkorn University, Thailand, from 2017 to 2019. All 13 underwent whole exome sequencing that identified likely pathogenic genetic variants, all in WNT10A, in five patients. All five patients had second premolar agenesis, while three also had absent or peg-shaped upper lateral incisors. Patient 1 possessed a novel heterozygous duplication, c.916_918dupAAC (p.Asn306dup) in WNT10A. Patients 2 and 3 harbored a heterozygous and homozygous c.637G > A (p.Gly213Ser) in WNT10A, respectively. Patients 4 possessed a heterozygous c.511C > T (p.Arg171Cys) in WNT10A. Patient 5 harbored a homozygous c.511C > T (p.Arg171Cys) in WNT10A and a novel heterozygous c.413A > T (p.Asn138Ile) in EDARADD, suggesting digenic inheritance. We recruited another 18 family members of these five patients. Out of 23 participants, homozygous WNT10A variants were identified in 2 patients and heterozygous variants in 17 individuals. Both homozygous patients had NSTA. Eight out of 17 heterozygous individuals (8/17) had NSTA or a peg-shaped lateral incisor, indicating a 47% penetrance of the heterozygous variants or 53% (10/19) penetrance of either homozygous or heterozygous variants in WNT10A. The frequencies of the c.511C > T in our in-house 1,876 Thai exome database, Asian populations, and non-Asian populations were 0.016, 0.005–0.033, and 0.001, respectively; while those of the c.637G > A were 0.016, 0.004–0.029, and 0.000, respectively. In conclusion, our study reports two novel variants with one each in WNT10A and EDARADD, expanding the genotypic spectra of NSTA. Second premolar agenesis is a common phenotype in affected individuals with variants in WNT10A; however, its penetrance is incomplete. Lastly, the different frequencies of WNT10A variants, c.511C > T and c.637G > A, in diverse populations might contribute to the prevalence range of NSTA between continents.

Prevalence of dental anomalies in a sample of orthodontic Egyptian patients using orthopantograms

Objective The aim of this cross-sectional study was to investigate the prevalence of dental anomalies in a sample of Egyptian orthodontic patients. Patients and methods This is a retrospective study where 435 digital orthopantograms taken of patients, ranging in age from 14 to 30 years with a mean age of 19 years were studied. The patients were presented for treatment at a private practice in Cairo during the period from 2017 to 2019. The orthopantograms were reviewed for impactions (including and excluding third molars), congenitally missing teeth or hypodontia (including and excluding third molars), ectopic eruption, microdontia (peg-shaped and small-sized maxillary lateral incisors), rudimentary 8's, root dilacerations and supernumerary teeth. Results Excluding third molars, the number of patients that had at least one dental anomaly was 183 or 42.1%. The prevalence of patients with impacted teeth was 66 (15.2%), while the prevalence of congenitally missing teeth was 44 (10.1%). Equal prevalence between males and females was recorded for impacted maxillary permanent canines (M = 16, F = 16) and congenitally missing maxillary permanent canines (M = 1, F = 1). The least prevalence were microdontia (n = 15, 3.4%), dilacerated roots (n = 8, 1.8%) and supernumerary teeth (n = 8, 1.8%). Rudimentary wisdom teeth count was 12 (2.8%) out of the total sample with only maxillary third molars being affected. The prevalence of impacted third molars was 25% (n = 109, M = 27, F = 82). The prevalence of congenitally missing third molars (at least one missing third molar) was 19.3% (n = 84, M = 22, F = 62). Females showed higher prevalence than males for all anomalies except for impacted mandibular permanent canines where males were higher than females (M = 9, F = 5), impacted upper incisors and upper first premolars (M = 1, F = 0) and supernumerary teeth (M = 6, F = 2). The prevalence of patients with impacted permanent second molars was 4.6%. Conclusions Excluding third molars, the most common dental anomaly was impaction followed by teeth agenesis. The most prevalent impaction was the maxillary permanent canine and the most congenitally missing teeth were the maxillary lateral incisors. Root dilacerations and supernumerary teeth were the least common anomalies. Congenitally missing and impacted third molars constitute a large segment of dental anomalies and must be evaluated separately. A large variation exists between the different populations regarding the prevalence of the various anomalies.

Coexisting Peg-Shaped Lateral Incisor and Hypodontia in a 9-Year-Old Child

Anomaly (Greek, anomalos; irregular) is a deviation from what is regarded as normal, standard, or expected. Disturbance of the epithelium along with mesenchymal interactions markedly alters the normal sequence of odontogenesis, which represents as developmental anomaly of teeth. This is dependent on the developmental stage during which the alteration takes place. Various anomalies could take place, e.g., alteration of number, structure, size, and/or shape. More than 300 genes have been identified in literature that are expressed in teeth responsible for odontogenesis. Defects in any of these genes result in the alteration of the development of tooth. Understanding the etiology of each dental anomaly helps not only in identification but also assists in determining the course of the treatment.