Introduction: The Emergency Department (ED) is a quite stressful workplace for nurses, affecting their quality of life. The existence of factors that affect the quality of life of ED nurses in daily clinical practice, leads to exhausted nurses. Consequently, there is a need to find the factors and the implementation of interventions that will improve the quality of life of nurses. Purpose: To investigate the factors that affect the quality of life of nurses in children's and adult hospitals. Method: The sample of this cross-sectional study consisted of ED nurses in children's and adult hospitals in Greece. To assess the nurses' quality of life, the WHOQOL-BREF questionnaire was used for the ED nurses. Analysis was done with IBM SPSS 26.0. A value of p<0.05 was considered as the level of significance and all statistical tests were two-tailed. Results: Study population included 210 nurses. No statistical significance was found for the relationship between pediatric ED nurses and adult ED nurses regarding their quality of life, sleep, and fatigue. However, a statistically significant relationship was found regarding social relationships tending to a better score in pediatric nurses compared to adults (p=0.011). In all five dimensions of life evaluated by the tool, the quality of life of the nurses in our sample was at moderate levels (Mean-General=69.32, Mean-Physical health=64.70, Mean-Psychological health=67.85, Mean-social relations=69.01 and Mean-Environment =57.60). Conclusion: One or more factors are sufficient to affect or have an impact on the quality of life, sleep completeness and fatigue levels of ED nurses.
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