Pediatric Asthma Quality Of Life Questionnaire Research Articles

Validity of the Pediatric Asthma Quality of Life Questionnaire in Polish children

Although the Pediatric Asthma Quality of Life Questionnaire (PAQLQ) was translated for use in Polish asthmatic children, it is necessary to confirm that its validity, reliability, and the accuracy of the responses are not influenced by culture difference. Therefore, the objective of this study was to validate the Polish version of the Pediatric Asthma Quality of Life Questionnaire. This was a 9-week period cohort study. The patients were interviewed using the PAQLQ on four occasions: at baseline, 1 wk after inclusion, and after 5 and 9 wk. At each clinic visit, lung functions test and NO measurements were performed. Asthma control (according to GINA) was assessed throughout the study. One hundred and one patients completed the study. At all visits, moderate correlations (from r = -0.51 to -0.68) between all PAQLQ domains and the asthma diary were observed. We noticed a significant improvement in the understanding of the questions during the last visit compared to baseline. The gradient of correlation coefficients between the symptoms domain of PAQLQ and asthma diary was observed across study visits. The standards of reliability defined by Cronbach's α-coefficient (from 0.75 to 0.91) were fulfilled in all domains of the questionnaire, at all visits. We found a higher increase in PAQLQ score in patients who obtained asthma control compared to those who lost control during the study. There was no relation between PAQLQ and FeNO. At all visits, moderate correlations (from r = -0.51 to -0.68) were shown between all PAQLQ domains and the asthma diary. We showed that Polish version of PAQLQ is valid and reliable among our study group. Moreover, as far as clinical practice is concerned, PAQLQ seems to be a useful tool for monitoring asthma in children especially based on the physician's grading of asthma severity according to GINA guidelines.

Effect of an intranasal corticosteroid on exercise induced bronchoconstriction in asthmatic children

Allergic rhinitis and exercise induced bronchoconstriction (EIB) are common in asthmatic children. The aim of this study was to investigate whether treatment of allergic rhinitis with an intranasal corticosteroid protects against EIB in asthmatic children. This was a double-blind, randomized, placebo-controlled, parallel group study. Subjects aged 12-17 years, with mild-to-moderate asthma, intermittent allergic rhinitis and ≥ 10% fall in FEV(1) at a screening exercise challenge were randomized to 22 ± 3 days treatment with intranasal fluticasone furoate or placebo. The primary outcome was change in exercise induced fall in FEV(1) . Secondary outcomes were changes in the area under the curve (AUC), asthma control questionnaire (ACQ), pediatric asthma quality of life questionnaire (PAQLQ), and exhaled nitric oxide (FeNO). Twenty-five children completed the study. Mean exercise induced fall in FEV(1) (± SD) decreased significantly (95% CI: 0.7-18.2%, P = 0.04) in the fluticasone furoate group from 28.4 ± 15.8% to 19.0 ± 13.8%, compared to the placebo group (27.4 ± 16.0% to 27.4 ± 19.2%). The change in AUC was not significantly different between treatment groups. However, within the fluticasone furoate group the AUC decreased significantly (P = 0.01). Although total PAQLQ score did not improve, the activity limitation domain score improved significantly within the fluticasone furoate group (P = 0.03). No significant changes were observed in FeNO and ACQ. Treatment of allergic rhinitis in asthmatic children with an intranasal corticosteroid reduces EIB and tends to improve quality of life.

Effects of Acupuncture-like Transcutaneous Electrical Nerve Stimulation on Children with Asthma

Objective: To evaluate the effects of acupuncture-like transcutaneous electrical nerve stimulation (AL-TENS) on children with asthma. Methods: After an 8-week run-in period, the experimental group were assigned to treatment with AL-TENS, whereas the control group did not receive AL-TENS. A total of 43 children with asthma were recruited from a hospital and an elementary school. All the cases had been diagnosed as having asthma by physicians. The outcome measures included pulmonary function tests (PFTs), heart rate turbulence (HRT), heart rate variability (HRV), and pediatric asthma quality-of-life questionnaire (PAQLQ). Results: After 8 weeks of AL-TENS, there were no significant differences on forced vital capacity (FVC), FEV1/FVC, and peak expiratory flows (PEFs) between the two groups. The HRT is the physiological, biphasic response of the sinus node to premature ventricular contractions. In the experimental group, the mean HRT was statistically significant between pretest and posttest. The HRV and the PAQLQ showed no difference, but in the experimental group, the subscale of the PAQLQ (particularly activity) improved significantly more than the pretest scores. Furthermore, there were no differences in PFTs and HRV after 8 weeks of AL-TENS between the two groups. Conclusions: The PAQLQ activities of the experimental group improved significantly more than those of the control group. Reasons may include: 1) the asthma cases were stable and the cases were on stable status and 2) the degree of airway remodeling was less. It is suggested that in the future, treatment frequency and the long-term follow-up for evaluating the effects of AL-TENS on children with asthma should also be considered.

Specific immunotherapy improves asthma related quality of life in childhood

Background Asthma is the most common chronic illness in childhood and really affects the everyday life of patients who suffer from it. Since asthma is a common disease, there is a great endeavour to achieve the most appropriate treatment option. Despite inhaled corticosteroids and leukotrien receptor antagonists both being routinely used in asthma treatment, specific immunotherapy is still questioned. There are numerous aspects affecting asthma-related quality of life, such as age; seasons; disease control and severity etc, which are well studied -apart from the type of treatment. With this study we aimed to stress the influence of asthma treatment on quality of life. Methods A total of 102 children, aged 6–18 years, were assigned to classic asthma therapy ( n=50) and specific immunotherapy ( n=52). The quality of life is assessed using the Standardized Pediatric Asthma Quality of Life Questionnaire (PAQLQ) interviewer-administered Turkish version. Pulmonary function testing was performed on the same day, after the questionnaire was completed. Results The PAQLQ total scores were significantly higher in the specific immunotherapy group ( p<0.001). Apart from emotional function domain scores; symptoms domain and activity limitation domain scores were higher in the specific immunotherapy group. Emotional function domain scores were similar in the two groups ( p>0.05). There were no statistically significant differences in pulmonary function testing results between the two groups ( p>0.05). There was a linear correlation between FEV1%, FVC level and total and domain scores of PAQLQ with Spearman Correlation tests.

Quality of life protocol in the early asthma diagnosis in children

Asthma is considered an important problem in children and influences on their everyday functioning. This study was concerned with the impact of asthma on the health-related quality of life (HRQOL) of newly recognized pediatric asthma patients and their parents. Patients were identified by a general respiratory survey. HRQOL was assessed by self-report measures: disease-specific questionnaire for children, the Pediatric Asthma Quality of Life Questionnaire (PAQLQ) and generic for parents-the Quality of Life in Child's Chronic Disease Questionnaire (QLCCDQ). Twenty-nine newly diagnosed asthmatic children aged 7-11 years (mean age = 8.6; SD = 1.4) were identified from a population-based respiratory health survey. The most impaired HRQOL domains differed in parents and children. In children, activity limitation was the most impaired; however in parents, emotional functioning and symptom perception domains were most impaired. There were no statistically significant differences in patient and parental HRQOL observed in either the group where symptoms were present or in the group were symptoms were not present. Baseline spirometry showed correlation for FEV(1)%FVC and PAQLQ symptom domain (r = 0.42). Exercise test showed correlations between FEV(1)%FVC and QLCCDQ emotional domain (r = 0.7); MEF 25-75% and family roles (r = 0.81), as well as social functioning (r = 0.81). Activity limitation on the PAQLQ correlated with the MEF 25-75% (r = 0.44) and PEF (r = 0.55). HRQOL newly recognized children with asthma and their parents does not correlate closely with clinical status. Patient and parental HRQOL should be considered as independent dimensions.

Versão brasileira do Paediatric Asthma Quality of Life Questionnaire: validação de campo

To assess the psychometric properties of the official Brazilian Portuguese-language version of the Paediatric Asthma Quality of Life Questionnaire (PAQLQ) in a representative group of Brazilian children and adolescents with asthma. A total of 125 individuals with asthma, aged 8-17 years and being monitored at a pediatric pulmonology outpatient clinic in the city of Porto Alegre, Brazil, completed the PAQLQ. Validity was assessed by means of convergent validity (correlation between PAQLQ domains and those of the Pediatric Quality of Life Inventory (PedsQL) 4.0. Reliability was assessed by determining internal consistency (Cronbach's alpha coefficient), reproducibility (intraclass correlation coefficient), sensitivity to change (effect size), and discriminatory power (floor/ceiling effects). The mean age was 11 years, and 75 (60%) of the participants were male. The mean PAQLQ total score was 5.1, with floor/ceiling effects < 10%. Correlations between PAQLQ domains and the PedsQL 4.0 domains were acceptable (r = 0.37-0.40). The Cronbach's alpha coefficient for the total score was 0.93, ranging from 0.72 to 0.88 for the domains. The overall effect size was 0.60 (range: 0.45-0.60), whereas the overall intraclass correlation coefficient was 0.80 (range: 0.66-0.79). The official Brazilian Portuguese-language version of the PAQLQ showed good psychometric performance, confirming its cultural adequacy for use in Brazil.

Assessing validity of the adapted Arabic Paediatric Asthma Quality of Life Questionnaire among Egyptian children with asthma

The recent focus in asthma management is rendering children a better quality of life (QOL). Validity and reliability of an adapted Arabic translation of the Paediatric Asthma Quality of Life Questionnaire (PAQLQ-A) among Egyptians was assessed in a cohort of 103 asthmatic children aged 8-16 years. Discriminative validity of mean scores was significantly higher among mild asthmatics than those with moderate/severe asthma. Construct validity of domains was significantly negatively correlated with clinical severity score. Reliability and internal consistency were assessed using Cronbach alpha coefficient (alpha = 0.84). Reproducibility and responsiveness were high among both stable and unstable asthma patients. PAQLQ-A is valid and reliable for assessing QOL among Egyptian asthmatic children.

Impact of asthma among primary attention children

Asthma is one of the chronic diseases that generate an impact on quality of life and major health care expenses. To evaluate the impact of asthma on primary attention expenses, the health related quality of life (HRQOL) and the sanitary resources use. Follow up of a cohort of 56 asthmatic children aged 6 to 14 years (56% women), during 12 months. The severity and the impact of the disease on HRQOL was assessed using the International Study of Asthma and Allergies in Childhood (ISAAC) video questionnaire and the Pediatric Asthma Quality of Life Questionnaire (PAQLQ) respectively Costs were derived from the number of medical attentions, hospital admissions, medication requirements, school absenteeism among patients and work absenteeism among caregivers. Patients required twice the number of medical attentions than the general population. Fourteen percent of children had severe asthma. Compared with subjects without severe asthma, the latter required more attentions (3.8 and 9.7 attentions per year respectively, p< 0.01), had a lower PAQLQ score (4.1 +/-0.11 and 5.2 +/- 1 respectively, p< 0.05) and a higher school absenteeism (10 and 27 days per year respectively, p < 0.01). Medication use was not different between patients with and without severe asthma. They early cost per patient was $ 106,550 (Chilean pesos). Asthma has a great impact on HRQOL and the use of primary attention resources, specially those children with severe asthma.

Impacto del asma en escolares de dos centros de salud primaria

Asthma is one of the chronic diseases that generate an impact on quality of life and major health care expenses.To evaluate the impact of asthma on primary attention expenses, the health related quality of life (HRQOL) and the sanitary resources use.Follow up of a cohort of 56 asthmatic children aged 6 to 14 years (56% women), during 12 months. The severity and the impact of the disease on HRQOL was assessed using the International Study of Asthma and Allergies in Childhood (ISAAC) video questionnaire and the Pediatric Asthma Quality of Life Questionnaire (PAQLQ) respectively Costs were derived from the number of medical attentions, hospital admissions, medication requirements, school absenteeism among patients and work absenteeism among caregivers.Patients required twice the number of medical attentions than the general population. Fourteen percent of children had severe asthma. Compared with subjects without severe asthma, the latter required more attentions (3.8 and 9.7 attentions per year respectively, p< 0.01), had a lower PAQLQ score (4.1 +/-0.11 and 5.2 +/- 1 respectively, p< 0.05) and a higher school absenteeism (10 and 27 days per year respectively, p < 0.01). Medication use was not different between patients with and without severe asthma. They early cost per patient was $ 106,550 (Chilean pesos).Asthma has a great impact on HRQOL and the use of primary attention resources, specially those children with severe asthma.

Quality of life and activity of children suffering from bronchial asthma

ObjectiveThe aim of this article was to analyze the quality of life of children suffering from bronchial asthma and to analyze their everyday activity.MethodsThe research was conducted in 137 children. The following questionnaires were used in the study: Pediatric Asthma Quality of Life Questionnaire (PAQLQ) and a questionnaire designed by the authors specifically for the purpose of the study.ResultsThe findings of the study show that illness duration (r = -0.2; P = 0.22) and gender (P = 0.37) do not influence the quality of life. It appears that among children ill with asthma a higher level of quality of life is typical for the children who live in the country side in comparison with those from cities (P < 0.05). The comparison was also made in terms of everyday activity of children ill with asthma and non-asthmatic children. The children ill with asthma displayed less social contacts with peers/friends (P < 0.05) and they performed less physical activities (P < 0.05).ConclusionsThe study points to the possible beneficial effects of activating children's social interactions, creating conditions for appropriate development of their social competences, and of stress reduction connected with social interactions. Asthmatic children should also be encouraged to intensify appropriate physical activity.

The Serbian Version of the Pediatric Asthma Quality of Life Questionnaire in Daily Practice

Asthma is the most common chronic disease in children and adolescents and a serious global health problem, thus severely affecting the health related quality of life (HRQL). This study was aimed at exploring the potential role of the Serbian, self administered version of the Pediatric Asthma Quality of Life Questionnaire (PAQLQ) in the routine clinical evaluation of children suffering from bronchial asthma. One hundred Serbian children and adolescents (62 males and 38 females), aged 7 to 17 years, affected by allergic asthma, were enrolled. Each patient was evaluated once, and asthma control and severity were assessed, spirometry was performed, FeNO measurements were performed and the patients completed the self-administered version of the PAQLQ. PAQLQ differed according to asthma severity, NO variation and Asthma Control Test (ACT) score. No correlations were found between the questionnaire's score and FEV1 percent of predicted. The Serbian version of the PAQLQ is a feasible aid to clinical measurements and used in routine practice gives a good insight into asthma control and severity.

Use of the Italian version of the Pediatric Asthma Quality of Life Questionnaire in the daily practice: results of a prospective study

BackgroundAsthma is a serious global health problem and its prevalence is increasing, especially among children. It represents a significant social and economic burden, and it can severely affect the health-related quality of life (HRQL) of patients. Among the numerous questionnaires aiming at evaluating asthma HRQL in children, the Pediatric Asthma Quality of Life Questionnaire (PAQLQ) has proved to have good measurement properties.The present study was aimed at investigating the possible role of the Italian, self-administered version of the PAQLQ in the routine clinical evaluation of children affected by bronchial asthma.Methods52 Italian children and adolescents (40 males and 12 females), aged 6 to 17 years, affected by allergic asthma, were enrolled. Each patient was evaluated twice, and at each visit asthma control and severity were assessed, spirometry was performed and the patients completed the self-administered version of the PAQLQ.ResultsThe questionnaire was well-accepted and understood by the children. Children showed an overall good quality of life, with mild impairment in the activity and emotional function domains. The PAQLQ showed an overall good correlation with the clinical and functional indexes that are normally evaluated in follow-up visits of asthmatic patients. The PAQLQ appeared to be strongly related to asthma control, both at the first (p < 0.01) and second (p < 0.001) time of the study. The PAQLQ was also seen to decrease with increasing asthma severity. The results suggest a better compliance of the children towards completion of the questionnaire at t1. Finally, the PAQLQ does not appear to discriminate HRQL in patients with good lung function.ConclusionThe Italian version of the PAQLQ is a quick-to-administer aid to clinical activity and can add valuable information to symptom reports, objective measurements and clinical assessment of asthma control and severity in daily clinical practice. Re-administration at each follow-up visit allows HRQL to be monitored over time.

Development and Initial Validation of a Pictorial Quality of Life Measure for Young Children with Asthma

To develop and assess the psychometric properties of a pictorial version of the Pediatric Asthma Quality of Life Questionnaire (PAQLQ). A pictorial PAQLQ was administered to 101 children with mild to severe asthma between 5 and 7 years of age. A subgroup of 48 children followed longitudinally completed the established version of the PAQLQ. A confirmatory factor analysis with modifications supported the factor structure of the established PAQLQ. The pictorial measure exhibited internal consistency reliability and convergent, discriminant, and predictive validity. Results suggest that the pictorial version of the PAQLQ has an underlying factor structure that is similar to that of the established PAQLQ. Future research with larger and diverse samples is needed to confirm the factor structure of the pictorial PAQLQ.

Quality of Life in Asthmatic Adolescents: An Overall Evaluation of Disease Control

Objective. to evaluate the relative impact of reported symptoms, school absenteeism, hospital admission, medical visits, and the presence of emotional and behavioral disorders on the health-related quality of life (HRQL) of low income asthmatic adolescents. Methods. Asthmatic adolescents were randomly selected among public schools in Belo Horizonte/MG, Brazil. Asthma severity was rated according to the Global Initiative for Asthma (GINA) classification. Emotional and behavior disorders (EBDs) were evaluated through the Strengths and Difficulties Questionnaire. HRQL was assessed through the Pediatric Asthma Quality of Life Questionnaire (PAQLQ). PAQLQ score was analyzed for each intervening variable. Multivariate regression analysis was conducted. Results. One hundred and forty-six adolescents participated in the present study, 45% being male and age ranging from 14 to 16 years old. Mean PAQLQ score was 5.7 ± 1.3 SD, with no significant difference regarding sociodemographic characteristics, except for gender (p = 0.001). The regression equation of the final model for the multivariate analysis was as follows: Mean PAQLQ score = 1.88 (Constant) − 0.42 gender + 1.14 nighttime symptoms + 0.69 medical visits in the past 12 months + 0.95 EBDs. Therefore, if the other variables remained constant, PAQLQ score: reduced in 0.42 points for females (p = 0.01); increased in 1.14 when there were no nighttime symptoms (p < 0.01); increased in 0.69 when there was no medical visit for respiratory problems within the past 12 months (p < 0.01); and increased in 0.95 when no EBDs were present (p < 0.01). This model was able to explain approximately half of the variation found in PAQLQ score (R-Sq = 49.4%). Conclusions. HRQL of asthmatic adolescents is influenced by the complex interaction among several factors: the severity of clinical symptoms, morbidity, gender, and the psychological resources available so as to deal with such difficulties. A careful evaluation of HRQL is essential in order to capture feelings and subjective perceptions, which are not investigated by the conventional evaluation of asthma control.

Does Long-Term Regular Swimming Have an Influence on Quality of Life, Anxiety and Depressive Symptoms of Adolescents with Asthma?

Purpose: The aim of our investigation was to compare the quality of life (QoL), anxiety and depressive symptoms of regular swimmer and non-swimmer young asthmatics. Methods: 24 swimmer asthmatics, who took part in a complex swimming exercise programme, and 51 non-swimmer asthmatics were asked to fill out the Hungarian validated form of the Pediatric Asthma Quality of Life Questionnaire (PAQLQ), the Spielberger State Anxiety Inventory for Children (H. STAIC) and the Child Depression Inventory (CDI). Results: No difference was found between swimmer and non-swimmer asthmatic groups regarding QoL, anxiety and depressive symptoms. In the group of swimmer asthmatics significant activity impairment was found in PAQLQ ( p < 0.0001). Non-swimmer asthmatic girls show significantly more anxiety symptoms than boys ( p = 0.023). Furthermore, girls have a tendency to show more depressive symptoms compared to boys. Depressive symptoms are significantly fewer in the swimmer and non-swimmer asthmatic boy groups than in th...

Attention Deficit and Hyperactivity Symptoms in Children with Asthma

Background. Asthma that is chronic may influence children's behavioral health and quality of life (QoL) negatively. Objective. To evaluate the frequency of attention deficit and hyperactivity symptoms in children with asthma and to determine if these symptoms are associated with a deterioration of QoL. Methods. Mothers of 62 children with moderate asthma and those of 38 healthy children aged between 7–12 years were included in the study. Conners' Parent Rating Scale-48 (CPRS), a 48-item multiple-choice questionnaire, was completed by the mothers to identify attention deficit and hyperactivity symptoms in children. The Pediatric Asthma Quality of Life Questionnaire (PAQLQ) was filled in by children to measure QoL. Results. Mean age was 9.2 ± 1.5 years for asthmatic children (37 male, 25 female) and 10.1 ± 1.3 years for control group (20 male, 18 female). The two groups were similar regarding age and sex. Attention deficit score in the asthma group was significantly higher than that in the control group (p = 0.01). The frequency of hyperactivity was higher in the asthmatic group but the difference between the groups was not significant (p = 0.36). Attention deficit and hyperactivity scores of Conners-P were not correlated with PAQLQ scores (regarding total, activity, emotional and symptom domains). Conclusion. Increased rates of attention deficit symptoms in children with asthma, as reported by mothers, might reflect the negative impact of asthma on neurobehavioral health. Asthmatic children, especially the ones who display attention deficit symptoms, must be considered for further evaluation regarding attention deficit hyperactivity disorder.

Exercise Training on Disease Control and Quality of Life in Asthmatic Children

Aerobic training has been shown to be effective in improving cardiopulmonary fitness in asthmatic children. However, the actual impact of physical training on clinical indicators of disease control remains controversial. Thirty-eight children with moderate to severe persistent asthma were randomly assigned to control (N=17) and training (N=21) groups. Spirometry, exercise challenge, and maximum incremental cardiopulmonary exercise tests were performed 16 wk apart. Daily doses of inhaled steroids and Pediatric Asthma Quality of Life Questionnaire (PAQLQ) scores were also recorded. Physical training was associated with significant improvements in physiological variables at peak and submaximal exercise (P<0.05); in contrast, no significant changes were found in controls. Severity of exercise-induced bronchoconstriction (EIB) and postexercise breathlessness were significantly lessened in trained patients; improvement in fitness and EIB, however, were not linearly related (P>0.05). In addition, PAQLQ scores improved only in trained children (P<0.01). Daily doses of inhaled steroids were reduced in trained patients (52%), but they remained unchanged or increased in controls (70.6%) (P=0.07). Supervised exercise training might be associated with beneficial effects on disease control and quality of life in asthmatic children. These data suggest an adjunct role of physical conditioning on clinical management of patients with more advanced disease.

Commentary on Rydström I, Dalheim‐Englund A‐C, Holritz‐Rasmussen B, Möller C &amp; Sandman P‐O (2005) Asthma – quality of life for Swedish children. Journal of Clinical Nursing 14, 739–749

Commentary on Rydstrom I, Dalheim-Englund A-C, Holritz-Rasmussen B, Moller C & Sandman P-O (2005) Asthma - quality of life for Swedish children. Journal of Clinical Nursing 14, 739-749.

Assessment of the Psychometric Properties of the Paediatric Asthma Quality of Life Questionnaire (PAQLQ) in Moderate to Severe Pediatric Asthma Patients

Assessment of the Psychometric Properties of the Paediatric Asthma Quality of Life Questionnaire (PAQLQ) in Moderate to Severe Pediatric Asthma Patients

ABS30: Validation of the ACQ (Juniper) in children: A pilot study

The Asthma Control Questionnaire (ACQ-Juniper) is widely used as a clinical endpoint in clinical trials. It has been validated for use in adults, but not in children. To carry out a pilot project look at the acceptability of carrying out the ACQ in children in a primary care setting and the correlation of the ACQ score with other measures of asthma control. 15 children (age range 6–16 yrs and median ICS dose 200 mcg BDP (or equivalent) attending 2 primary care asthma clinics in the United Kingdom were enrolled. Assessments were made at 2 -weekly intervals over 12 weeks. The 6-question ACQ was used together with RCP 3 Questions, FEV1, miniAsthma Quality of Life Questionnaire(mini-AQLQ) Paediatric Asthma Quality of Life Questionnaire (PALQ), bronchodilator use and exhaled nitric oxide (eNO) levels. Routine clinical care was allowed to continue. 105 measurements of ACQ were made over the 12 week period. The questionnaire was easy to complete although younger children needed some help with interpretation from their parents. There was a strong cross-sectional correlation with PAQLQ (Spearmann's rank correlation r = 0.85 p < 0.001), moderate correlation with the RCP 3 questions (r = 0.4 p< 0.001) and bronchodilator use (r = 0.4. p < 0.001) and weak or no correlation with eNO (r = 0.20 p < 0.05) and FEV-1% predicted (r = −0.12, ns) There was a strong longitudinal correlation between changes in ACQ and change in PALQ (r= 0.66, p<0.001), moderate correlation between changes in RCP 3 question score (r= 0.48, p < 0.001) and bronchodilator use (r = 0.42, p < 0.01). There was no correlation with changes in eNO (r = 0.15, ns) and FEV-1% predicted (r= 0.02, ns). The 6- question ACQ is easy to use in children age 6–16 with asthma although parental help may be needed for younger children. It shows cross-sectional and longitudinal validity with some other parameters of asthma control. A larger multi-centre validation study in primary care is planned. Conflict of interest and funding No. Funding: Funded by RCGP, United Kingdom.