Peculiar Variations Research Articles

Testing the sources of the peculiar abundances in globular clusters

This work aims to analyze some of the polluters proposed in the self-enrichment scenarios put forward to explain the multiple populations in globular clusters (GCs), extending previous studies. Three scenarios with different polluter stars were tested: asymptotic giant branch stars (AGBs), high-mass interacting binaries (IBs), and fast rotating massive stars (FRMSs). With abundance data available from the Apache Point Observatory Galactic Evolution Experiment (APOGEE) survey and ΔY estimates from precise Hubble Space Telescope (HST) photometry, twenty-six clusters were studied, increasing the number of clusters in previous studies by more than a factor of three. We also included the study of the abundances of N, C, Mg, and Al, extending previous studies that mainly focused on the abundances of He, O, and Na. In addition, we constructed an empirical model to test whether one could explain the chemical signatures of the “enriched” population of GC stars with a fixed source and dilution process based on empirical data. In agreement with work by other authors, we found that the proposed polluters can generally predict the qualitative abundance patterns in GC stars and in some cases quantitatively predict some elements, but in most cases when we compare the model yields with the observations, we find that they cannot explain the entire set of observed abundance patterns. The empirical model succeeds in reproducing the abundances of Al for a given ΔY (and vice versa), showing that there is a direct relationship between Al and He, with one increasing proportionally to the other. However, the empirical model fails to reproduce the observed abundances of Na and N, in agreement with the results of previous works. The observed decoupling between the maximum abundances of CNO-cycle elements such as N and Na with those of Al and He provides new information and constraints for future models and could take us a step closer to understanding the origin of the peculiar abundance variations of GC stars.

Thyroidectomized patients on LT-4 therapy with advanced medullary thyroid carcinoma treated with selpercatinib show peculiar variations of thyroid function tests

Thyroidectomized patients on LT-4 therapy with advanced medullary thyroid carcinoma treated with selpercatinib show peculiar variations of thyroid function tests

Bayesian sensitivity of binary pulsars to ultra-light dark matter

Ultra-light dark matter perturbs the orbital motion of binary pulsars, in particular by causing peculiar time variations of a binary's orbital parameters, which then induce variations in the pulses' times of arrival. Binary pulsars have therefore been shown to be promising detectors of ultra-light dark matter. To date, the sensitivity of binary pulsars to ultra-light dark matter has only been studied for dark matter masses in a narrow resonance band around a multiple of the binary pulsar orbital frequency. In this study we devise a two-step, bayesian method that enables us to compute semi-analytically the sensitivity for all masses, also away from the resonance, and to combine several observed binaries into one global sensitivity curve. We then apply our method to the case of a universal, linearly-coupled, scalar ultra-light dark matter. We find that with next-generation radio observatories the sensitivity to the ultra-light dark matter coupling will surpass that of Solar-System constraints for a decade in mass around \(m eV \), even beyond resonance.

Multivariate statistical analysis approach to investigate the thermodynamic quantities of the benign alternative fuel

In order to extract meaningful interpretation from the large data and provide their value to the application areas, chemical data analysis has become a serious challenge in the development and applications of new protocols, tech-nique and methodologies for the mathematical modelling communities and other data science societies. Therefore, in the present work a rapid and robust box-and-whisker plot and multivariate principal component statistical tech-niques (PCA) are being proposed for the evaluations of the thermodynamic molecular properties data of the benign fuel structures. We observed that, the box-and-whisker plot technique successfully explored all of the thermochem-ical molecular properties precisely, and described symmetrical distribution of the data along the median values with respect to the rise in temperature. More-over, applying the PCA technique, the score-plots of PCs diagnosed the pecu-liar molecular properties variations after a certain peak of temperature with descendant variation in the statistical parameters. Furthermore, PCA parameters not only segregated the thermodynamic properties of propanol and butanol but also, their variations with the temperature. Thus, we concluded that, Box-whis-ker and PCA statistical techniques are robust and rapid method for the assess-ment and evaluation of the large molecular thermodynamic quantities data.

Thermal Injury to the Subhepatic Appendix Following Percutaneous Ultrasound-Guided Radiofrequency Ablation for Hepatocellular Carcinoma: A Case Report.

We present the first documented case of a fistula between the treated zone and the appendix after RFA in a patient with HCC. Contrast-enhanced CT and MRI revealed a subcapsular hepatic nodule with image findings of HCC located adjacent to the ascending colon and cecum. An ultrasound-guided core needle biopsy was subsequently performed to distinguish between hepatic metastasis and HCC. Post-RFA imaging identified a low-attenuating ablated area adjacent to an air-filled appendix. The patient later experienced complications, including increased liver enzymes and an abscess at the ablation site. Imaging revealed a fistulous tract between the RFA zone and the appendix. Over the following months, the patient underwent conservative treatment involving intravenous antibiotics and repeated percutaneous drainage, exhibiting eventual symptom relief and an absence of the fistulous tract upon subsequent imaging. This case highlights the rare complications that can arise during RFA due to peculiar anatomical variations, such as a subhepatic appendix, resulting from midgut malrotation and previous surgery. It is imperative for operators to be cognizant of potential anatomical variations when considering RFA treatment, ensuring comprehensive pre-procedural imaging and post-procedure monitoring. This case also emphasizes the potential viability of nonoperative management in complex scenarios in which surgical interventions pose significant risks.

Influence of Infrastructure and Operating Conditions on Energy Performance of DC Transit Systems

Energy efficiency is more and more important for modern electrified transportation systems, requiring an understanding of the various indexes of performance (regenerability, receptivity, and energy losses, thus including braking recovered energy and energy loss in catenary) and of the influence of the main system parameters (headway, line voltage, substation separation, etc.). By means of electromechanical simulation, the most relevant parameters and system conditions are identified as influencing the efficiency performance and optimization capability. Besides the assessment of such efficiency performance indexes, identifying their typical ranges of variation, one further outcome is the identification of characteristic system parameter combinations that lead to extreme variations in the system energy efficiency itself. Such peculiar variations are caused by occasionally synchronized patterns of trains along the line and result in a significant local increase or decrease in efficiency. Efficiency drop scenarios in particular should be taken into consideration for worst-case analysis and to devise effective mitigations. To this aim, the effect of differently distributed passenger stations is considered.

Photometric study of the supersoft X-ray source V Sge based on TESS data

ABSTRACT V Sge is a unique eclipsing cataclysmic binary and a recognized supersoft X-ray source (SSS). By collecting available data on eclipse timings of V Sge, including our observations, we compiled and obtained an O − C diagram to analyse the orbital period variations of V Sge. The O − C curve displays a downward parabolic course, which implies that the orbital period is decreasing continuously at a rate of dP/dt = −1.92(2) × 10−7 d yr−1 = −0.0166(2) s yr−1. The continuously decreasing orbital period may be mainly caused by mass transfer from the more massive secondary component during its evolution on the Kelvin–Helmholtz time-scale, as well as mass loss from the accretion disc surrounding the white dwarf. Therefore, we estimate that the mass-accretion rate is less than $2.667\times 10^{-7}\, {\rm M}_{\odot }\, \mathrm{yr}^{-1}$. It can be roughly estimated that V Sge might reach the Chandrasekhar limit in at least 1 Myr, then might explode as a type Ia supernova. In addition, the more continuous TESS light curves show peculiar variations, that is, there is a great difference in brightness between two adjacent orbital periods. We speculate that this may be mainly caused by the extinction effect of the uneven circumstellar matter.

Anatomic Variation of the Lateral Sinus in Patients With Idiopathic Intracranial Hypertension: Delineation With Black-Blood Contrast-Enhanced MRI.

Objectives: The purpose of this study was to describe the peculiar anatomic variations in the lateral sinus and analyze the patterns of cerebrospinal fluid (CSF) drainage by using high-resolution (HR) black-blood (BB) contrast-enhanced magnetic resonance imaging (MRI) in patients with idiopathic intracranial hypertension (IIH).Methods: Total 33 IIH patients who were found cerebral venous sinus stenosis (CVSS) by MR venography (MRV) were enrolled in this study. HR-BB contrast-enhanced MRI was used to assess the features of anatomical variations in transverse sinus and sigmoid sinus. The development of bilateral sinuses was firstly evaluated, including unilateral hypoplasia with contralateral dominance or bilateral balanced development. Then, four kinds of anatomical variations were eventually recorded, including circumscribed stenosis, arachnoid granulation (AG), fibrous septum (FS), and brain herniation (BH) into dural venous sinus (DVS).Results: Bilateral venous drainage dysfunction was found in 30(90.9%) patients, whereas only 3(9.1%) patients presented unilateral venous drainage dysfunction. There was no difference in clinical symptoms between the two groups. The most common case is hypoplasia in unilateral sinus combined with anatomic variation in the contralateral dominant transverse sinus such as AG and BH into DVS. Total of 52 anatomic variations were finally found in bilateral sinuses in 33 enrolled patients, including 19(36.5%)AGs, 12(23.1%)FS, 7(13.5%) BH into DVS and 14(26.9%) circumscribed stenoses. Moreover, 41(62.1%) lateral sinuses showed enhancement in T1-weight-enhanced MRI.Conclusions: Patients with CVSS almost had CSF outflow disorders, whatever bilateral equalization or unilateral hypoplasia with contralateral dominance. Four types of main anatomic variations, including circumscribed stenosis, AG, FS, and BH into DVS, caused venous reflux obstruction by elevating the intracranial press (ICP).

Analysis of D-Shaped Optical Fiber based Corrosion Sensor Using LMR and SPR Effects

This article presents the proposed structure and the simulation results from analytical and numerical modeling of two corrosion sensor elements in D-shaped optical fiber: one based on the lossy mode resonance (LMR) effect and the other based on the effect of surface plasmon resonance (SPR). In the first sensor element, a bilayer of titanium dioxide – aluminum (TiO2-Al) is deposited on the D-shaped region, operating in LMR conditions, while, in the second sensor element, an aluminum (Al) monolayer is deposited under D-shaped region, operating in SPR condition. The sensor elements can operate separately, enabling simultaneous two-parameter measurements at two different points, or they can operate in cascade configuration, increasing the operating range and sensitivity of the sensor set. The D-shaped region of the optical fiber is modeled with an analytical model based on the Fresnel formulation, and also with a numerical model, which uses the finite element method with the COMSOL Multiphysics 5.2 software. The transmission of light through the D-shaped region causes peculiar variations in each light polarization in each sensor element, depending on the metal thickness. Both regions are subject to a corrosive environment. The sensor elements are evaluated separately and in cascade configuration, using polarized and nonpolarized light. Finally, the obtained results show two resonance valleys for the same operating wavelength, resulting in a higher operating range with high sensitivity, compared to other corrosion sensor structures found in the literature.

Nasopharyngeal cancers in University of Port Harcourt teaching hospital: a five year review

<p class="abstract"><strong>Background:</strong> Nasopharyngeal cancer though an uncommon head and neck cancer, has high morbidity and mortality. It is a cancer that has peculiar geographic variations and hence has been studied by a lot of researchers globally. It however has not been studied as an entity in the South region. This study was to determine the clinical and histologic presentations as well as the prevalence of this disease in Port Harcourt.</p><p class="abstract"><strong>Methods:</strong> Hospital based retrospective review of all patients with confirmed diagnosis of nasopharyngeal cancer seen within the period of January 2014 to December 2018 at ENT Department University of Port Harcourt teaching hospital. The hospital records were the source of data. The demographics, clinical presentations, histology, investigations and outcome were all collated from the records and were analyzed with IBM SPSS version 25. </p><p class="abstract"><strong>Results:</strong> Forty-one patients were studied with age range of 12-85 years. The mean age was 43±15.1 years. Male to female ratio was 1.2:1. Age 40 to 49 years was the most affected. Nasopharyngeal carcinoma was the commonest cancer recorded 68.29% followed by non-Hodgkin’s lymphoma 19.5%. Keratinizing squamous cell carcinoma was the commonest histologic type 43.9%. Commonest symptoms were neck swelling and nasal congestion 24.55%. Age distribution showed a statistical difference with histology of cancer. Mortality of 4.87 was recorded; the rest was lost to follow up.</p><p class="abstract"><strong>Conclusions:</strong> Nasopharyngeal carcinoma is the commonest cancer in the nasopharynx. It is significantly related with age. Patients often present late and it has very high morbidity and mortality rate. Attention to early vague symptoms will enhance early diagnosis, treatment therefore prognosis.</p>

Raman evidence for absence of phase transitions in negative differential resistance thin film devices of niobium dioxide

We fabricate NbO2 thin films and measure their transport properties in simple devices. These could be potential components of future memristor devices because of peculiar conductivity variations observed as a function of device current. We find that threshold switching effects observed in the voltage control regime are better viewed in the current controlled regime where they can be understood in terms of a negative differential resistance phenomenon. No electronic or structural phase change is observed in the NbO2 thin films in this regime in the steady state, notably with in situ Raman measurements. In particular, both crystalline and amorphous films remain insulating since their resistance always decreases with an increase in temperature. However, a large decrease in resistivity corresponding to negative differential resistance is observed as current in the devices increases. Temperature is the parameter which induces this change in resistivity through thermal activation of carriers, confirming recent understanding of the phenomenon. Temperature changes are locally induced because of the power dissipated by the current in the device and the intrinsically low thermal conductivity of NbO2. This is confirmed by parameters extracted from the simulation of the phenomenon with different transport models. However, the simplest thermal activation model accounts for the observations in non-nanometric devices without the need for invoking more complex models. Finally, pulsed current can be used to provoke a structural, amorphous to crystalline phase transition in amorphous samples through a sudden local increase in temperature.

Heated transcritical and unheated non-transcritical turbulent boundary layers at supercritical pressures

Nominally zero-pressure-gradient fully developed flat-plate turbulent boundary layers with heated and unheated isothermal walls at supercritical pressures are studied by solving the full compressible Navier–Stokes equations using direct numerical simulation. With a heated isothermal wall, the wall temperature sets such that the flow temperature varies through the pseudo-critical temperature, and thus pseudo-boiling phenomena occur within the boundary layers. The pseudo-boiling process induces strongly nonlinear real-fluid effects in the flow and interacts with near-wall turbulence. The peculiar abrupt density variations through the pseudo-boiling process induce significant near-wall density fluctuations $\sqrt{\overline{\unicode[STIX]{x1D70C}^{\prime }\unicode[STIX]{x1D70C}^{\prime }}}/\overline{\unicode[STIX]{x1D70C}}\approx 0.4{-}1.0$ within the heated transcritical turbulent boundary layers. The large near-wall density fluctuations induce a turbulent mass flux $\unicode[STIX]{x1D70C}^{\prime }u_{i}^{\prime }$, and the turbulent mass flux amplifies the Favre-averaged velocity fluctuations $u_{i}^{\prime \prime }$ in the near-wall predominant structures of streamwise low-speed streaks that are associated with the ejection (where $u^{\prime \prime }<0$ and $v^{\prime \prime }>0$), while reducing the velocity fluctuations in the high-speed streaks associated with the sweep ($u^{\prime \prime }>0$ and $v^{\prime \prime }<0$). Although the near-wall low-speed and high-speed streak structures dominate the Reynolds-shear-stress generation, the energized Favre-averaged velocity fluctuations in the low-speed streaks enhance both the mean-density- and density-fluctuation-related Reynolds shear stresses ($-\overline{\unicode[STIX]{x1D70C}}\overline{u^{\prime \prime }v^{\prime \prime }}$ and $-\overline{\unicode[STIX]{x1D70C}^{\prime }u^{\prime \prime }v^{\prime \prime }}$) in the ejection event and, as a result, alter the Reynolds-shear-stress profile. The large density fluctuations also alter the near-wall viscous-stress profile and induce a near-wall convective flux $-\overline{\unicode[STIX]{x1D70C}}\widetilde{u}\widetilde{v}$ (due to non-zero $\widetilde{v}$). The changes in the contributions in the stress-balance equation result in a failure of existing velocity transformations to collapse to the universal law of the wall. The large density fluctuations also greatly contribute to the turbulent kinetic energy budget, and especially the mass flux contribution term becomes noticeable as one of the main positive terms. The unheated non-transcritical turbulent boundary layers show a negligible contribution of the real-fluid effects, and the turbulence statistics agree well with the statistics of an incompressible constant-property turbulent boundary layer with a perfect-gas law.

Photothermally Activated Nanocrystalline Oxynitride with Superior Performance in Flexible Field-Effect Transistors.

Photochemical reactions in inorganic films, which can be promoted by the addition of thermal energy, enable significant changes in the properties of films. Metaphase films depend significantly on introducing external energy, even at low temperatures. We performed thermal-induced, deep ultraviolet-based, thermal-photochemical activation of metaphase ZnOxNy films at low temperature, and we observed peculiar variations in the nanostructures with phase transformation and densification. The separated Zn3N2 and ZnO nanocrystalline lattice in amorphous ZnOxNy was stabilized remarkably by the reduction of oxygen defects and by the interfacial atomic rearrangement without breaking the N-bonding. On the basis of these approaches, we successfully demonstrated highly flexible, nanocrystalline-ZnOxNy thin-film transistors on polyethylene naphthalate films, and the saturation mobility showed more than 60 cm2 V-1 s-1.

Variations in the correlation between teleconnections and Taiwan's streamflow

Abstract. Interannual variations in catchment streamflow represent an integrated response to anomalies in regional moisture transport and atmospheric circulations and are ultimately linked to large-scale climate oscillations. This study conducts correlation analysis to calculate how summertime (July–September, JAS) streamflow data derived at 28 upstream and 13 downstream gauges in Taiwan correlate with 14 teleconnection indices in the current or preceding seasons. We find that the western Pacific (WP) and Pacific–Japan (PJ) patterns, both of which play a critical role in determining cyclonic activity in the western North Pacific basin, exhibit the highest concurrent correlations (most significant r = 0. 50) with the JAS flows in Taiwan. Alternatively, the Quasi-Biennial Oscillation (QBO) averaged over the period from the previous October to June of the current year is significantly correlated with the JAS flows (most significant r = −0. 66), indicating some forecasting utility. By further examining the correlation results using a 20-year moving window, peculiar temporal variations and possible climate regime shifts (CRSs) can be revealed. A CRS test is employed to identify suspicious and abrupt changes in the correlation. The late 1970s and 1990s are identified as two significant change points. During the intermediate period, Taiwan's streamflow and the PJ index exhibit a marked in-phase relationship (r > 0. 8). It is verified that the two shifts are in concordance with the alteration of large-scale circulations in the Pacific basin by investigating the changes in pattern correlation and composite maps before and after the change point. Our results suggest that empirical forecasting techniques should take into account the effect of CRSs on predictor screening.

Frequency and anatomical features of the mandibular lingual foramina: systematic review and meta-analysis.

Lingual mandibular foramina are peculiar anatomical variations often present on the bone surface of the inferior jaw. These structures host vascular and nervous anastomosis deriving from the branches of the submental artery, lingual artery, and the mylohyoid nerve. Reports pointed out intra-operative massive bleeding accidents during implant interventions occurred in this area. The aim of this systematic review and meta-analysis was to summarize quantitatively the features of the lingual foramina on the midline of the inferior jaw. We performed a systematic review and meta-analysis complying the PRISMA statement and registering it in PROSPERO database. The frequency rate of the foramina resulted to have a point estimate of 0.965. The means of the diameters showed to have a point estimate of 0.840 with a standard error of 0.06. The results showed a significant high frequency reported in the literature of this variation, with a quite important diameter, sign of significant caliber of the related vessels. Even if this variation is underreported in modern textbooks of oral anatomy, we suggest an accurate screening via CT scan pre-operatively. In addition, a proper risk management is necessary to minimize injure hazard and properly managing the vascular plexus of the anterior floor of oral cavity.

Comprehensive Genetic Landscape of Uveal Melanoma by Whole-Genome Sequencing

Uveal melanoma (UM) is a rare intraocular tumor that, similar to cutaneous melanoma, originates from melanocytes. To gain insights into its genetics, we performed whole-genome sequencing at very deep coverage of tumor-control pairs in 33 samples (24 primary and 9 metastases). Genome-wide, the number of coding mutations was rather low (only 17 variants per tumor on average; range 7-28), thus radically different from cutaneous melanoma, where hundreds of exonic DNA insults are usually detected. Furthermore, no UV light-induced mutational signature was identified. Recurrent coding mutations were found in the known UM drivers GNAQ, GNA11, BAP1, EIF1AX, and SF3B1. Other genes, i.e., TP53BP1, CSMD1, TTC28, DLK2, and KTN1, were also found to harbor somatic mutations in more than one individual, possibly indicating a previously undescribed association with UM pathogenesis. De novo assembly of unmatched reads from non-coding DNA revealed peculiar copy-number variations defining specific UM subtypes, which in turn could be associated with metastatic transformation. Mutational-driven comparison with other tumor types showed that UM is very similar to pediatric tumors, characterized by very few somatic insults and, possibly, important epigenetic changes. Through the analysis of whole-genome sequencing data, our findings shed new light on the molecular genetics of uveal melanoma, delineating it as an atypical tumor of the adult for which somatic events other than mutations in exonic DNA shape its genetic landscape and define its metastatic potential.

A vaginal drug delivery model

Efficient drug delivery at vaginal cavity is often a challenge owing to its peculiar physiological variations including vast differences in pH. Keeping in view this attribute of the target site, the current work was aimed at developing formulation strategies which could overcome this and successfully deliver molecules like itraconazole through SLNs. Optimized SLNs with the given composition was selected for further development into mucoadhesive and thermosensitive gel. Stearic acid and Compritol 888 (1:1, w/w ratio) as lipid, a mixture of 3% Poloxomer 188 and 0.5% sodium taurocholate as surfactant and organic to aqueous ratio of 10:50 was taken. Carbopol 934 and Pluronic F 127 were taken for the development of gel. Optimized gel exhibited a desired gelling temperature (35 °C); viscosity (0.920 PaS) and appreciable in vitro drug release (62.2% in 20 h). MTT assay did not show any cytotoxic effect of the gel. When evaluated in vivo, it did not exhibit any irritation potential despite appreciable bioadhesion. A remarkable decrease in CFUs was also observed in comparison with control and marketed formulation when evaluated in rat infection model. Thus, the proposed study defines the challenges for developing a suitable formulation system overcoming the delivery barriers of the vaginal site.

DR Tauri: Temporal variability of the brightness distribution in the potential planet-forming region

We investigate the variability of the brightness distribution and the changing density structure of the protoplanetary disk around DR Tau, a classical T Tauri star. DR Tau is known for its peculiar variations from the ultraviolet (UV) to the mid-infrared (MIR). Our goal is to constrain the temporal variation of the disk structure based on photometric and MIR interferometric data. We observed DR Tau with the MID-infrared Interferometric instrument (MIDI) at the Very Large Telescope Interferometer (VLTI) at three epochs separated by about nine years, two months, respectively. We fit the spectral energy distribution and the MIR visibilities with radiative transfer simulations. We are able to reproduce the spectral energy distribution as well as the MIR visibility for one of the three epochs (third epoch) with a basic disk model. We were able to reproduce the very different visibility curve obtained nine years earlier with a very similar baseline (first epoch), using the same disk model with a smaller scale height. The same density distribution also reproduces the observation made with a higher spatial resolution in the second epoch, i.e. only two months before the third epoch.

Statistical analysis of geomagnetic field variations during the partial solar eclipse on 2011 January 4 in Turkey

Some geophysical parameters, such as those related to gravitation and the geomagnetic field, could change during solar eclipses. In order to observe geomagnetic fluctuations, geomagnetic measurements were carried out in a limited time frame during the partial solar eclipse that occurred on 2011 January 4 and was observed in Canakkale and Ankara, Turkey. Additionally, records of the geomagnetic field spanning 24 hours, obtained from another observatory (in Iznik, Turkey), were also analyzed to check for any peculiar variations. In the data processing stage, a polynomial fit, following the application of a running average routine, was applied to the geomagnetic field data sets. Geomagnetic field data sets indicated there was a characteristic decrease at the beginning of the solar eclipse and this decrease can be well-correlated with previous geomagnetic field measurements that were taken during the total solar eclipse that was observed in Turkey on 2006 March 29. The behavior of the geomagnetic field is also consistent with previous observations in the literature. As a result of these analyses, it can be suggested that eclipses can cause a shielding effect on the geomagnetic field of the Earth.

Готическая традиция в творчестве Говарда Лавкрафта

The main motives of H. Lovecraft’s story “The Call of Cthulhu” are marked out in the article. They give the possibility to examine the writer’s creative activity in the context of the gothic tradition: doom of human civilization, overcoming the limits between modern and ancient worlds, between reality and dreams, perception of human life as mysticism and horror, aspiration to make the reader feel the reality of the fantastic plot. It is noted that these motives not only form the subject-composition structure of the story “The Call of Cthulhu” but at the same time unite H. Lovecraft’s works into the joint cycle. The advantage of this research is that H. Lovecraft’s prose is considered to be the link between E. Poe's novelistics and modern literature of “horror” genre. The thought that humanity is only one of the great variety of highly-advanced civilizations inhabited the Earth at different times becomes the main motive of H. Lovecraft’s works. The idea of projection of the consciousness of the ancient die off civilization representatives into the future is connected with this motive. In H. Lovecraft’s story the idea of the consciousness shift from one body into another is viewed in the context of the eternal subject of the fight of good and evil. In its turn the “dream in dream” motive creates the feeling of the current developments illusiveness with the characters of the story as well as with readers. In the result of the story “The Call of Cthulhu” analysis the conclusion that the atmosphere of fear, supernatural horror, mystery, appealing to infernal forces allows (in half-mystical or half-mythical way) to judge H. Lovecraft’s works as peculiar variations about the gothic themes is made. It is possible to claim with certainty that H. Lovecraft’s creative activity predetermined in many ways the development of the modern neo-gothic prose.