Alluvial systems affected by peat layer compaction of a variable degree are studied all over the world, especially in areas of large river deltas and coastal plains. Ordinarily studied Holocene peat accumulations do not reach thicknesses of more than 6–10 m. This paper documents four ancient alluvial systems affected by peat compaction during the Lower Miocene in large exposures of open-cast lignite mines within the Most Basin, Czech Republic. Field observations and the study of 3000 borehole sections showed a clear dependence of the thickness and composition of the underlying peat on the scale of the accommodation space for loading by younger alluvial sediments. If the underlying partly compacted peat was tens to hundreds of meters in thickness, significant deformations of the peat appeared during its loading, leading up to the formation of growth faults. In such cases, missing parts of the coal seams were also observed below the alluvial systems. Especially borehole data showed that a linear correlation exists between the thickness of the alluvial sediments and the maximum instantaneous available compaction capacity of the underlying peat.