This study aims to analyze the coordinated development of population growth and social security in Guangdong Province, and summarize the objective laws of development in various economic regions. The research aims to provide new insights for the government to promote the coordinated development of population growth and social security based on local conditions, formulate sustainable social security policies, improve the level of social security in Guangdong Province, and enrich the content of social security policy reform. The research methods include literature review, exploration of advanced theories and models from abroad, and processing of publicly available data from the Guangdong Provincial Government in 2020. Additionally, the study utilizes the principles of statistical measurement of variable coupling to calculate the coordination between population development and social security development in Guangdong Province, and explains the differences in coordination levels among different regions through empirical research methods.The results indicate a significant positive correlation between population development and social security development in most regions of Guangdong Province. Regions with higher levels of population development tend to have higher levels of social security, and there is a similar spatial distribution pattern between the two. However, there is also a significant imbalance in development among different regions. Based on the coordination level between population development and social security development, the Pearl River Delta region is categorized as having high-quality coordination, the mountainous areas are classified as moderately imbalanced, and the western and eastern regions are deemed severely imbalanced. In conclusion, data analysis suggests that the Guangdong Provincial Government needs to further deepen the reform of the social security system, promote economic integration, strengthen the construction of social security institutions, narrow the wealth gap between regions in Guangdong Province, maintain coordinated development among different regions, promote further economic development in Guangdong, attract more talent to stay in the province, and achieve the goal of shared economic development for all citizens.