Abstract Objective . To determine the effectiveness of massage therapy for relieving the symptoms of carpal tunnel syndrome (CTS). Methods. Sixteen adults with CTS symptoms were randomized to a 4-week massage therapy or control group. Participants in the massage therapy group were taught a self-massage routine that was done daily at home. They were also massaged once a week by a therapist. The participants' diagnosis was based on a nerve conduction velocity test, the Phalen test, and the Tinel sign test performed by a physician. The participants were also given the state trait anxiety inventory (STAI), the profile of mood states (POMS), a visual analog scale for pain and a test of grip strength. Results. Participants in the massage therapy group improved on median peak latency and grip strength. They also experienced lower levels of perceived pain, anxiety, and depressed mood. Conclusion. The results suggest that symptoms of CTS can be relieved by a daily regimen of massage therapy.