Floods in southwestern Saudi Arabia, especially in the Asir region, are among the major natural disasters caused by natural and human factors. In this region, flash floods that occur in the Wadi Hail Basin greatly affect human life and activities, damaging property, the built environment, infrastructure, landscapes, and facilities. A previous study carried out for the same basin has effectively revealed zones of flood risk using such an approach. However, the utilization of the HEC–HMS (Hydrologic Engineering Center–Hydrologic Modeling System) model and IMERG data for delineating areas prone to flash floods remain unexplored. In response to this advantage, this work primarily focused on flood generation assessment in the Wadi Hail Basin, one of the major basins in the region that is frequently prone to severe flash flood damage, from a single extreme rainfall event. We employed a fully physical-based, distributed hydrological model run with HEC–HMS software version 4.11 and Integrated Multi-satellite Retrievals of Global Precipitation Measurement (IMERG V.06) data, as well as other geo-environmental variables, to simulate the water flow within the Wadi Basin, and predict flash flood hazard. Discharge from the wadi and its sub-basins was predicted using 1 mm rainfall over an 8-h occurrence time. Significant peak discharge (3.6 m3/s) was found in eastern and southern upstream sub-basins and crossing points, rather than those downstream, due to their high-density drainage network (0.12) and CNs (88.4). Generally, four flood hazard levels were identified in the study basin: ‘low risk’, ‘moderate risk’, ‘high risk’, and ‘very high risk’. It was found that 43.8% of the total area of the Wadi Hail Basin is highly prone to flooding. Furthermore, medium- and low-hazard areas make up 4.5–11.2% of the total area, respectively. We found that the peak discharge value of sub-basin 11 (1.8 m3/s) covers 13.2% of the total Wadi Hail area; so, it poses more flood risk than other Wadi Hail sub-basins. The obtained results demonstrated the usefulness of the methods used to develop useful hydrological information in a region lacking ungagged data. This study will play a useful role in identifying the impact of extreme rainfall events on locations that may be susceptible to flash flooding, which will help authorities to develop flood management strategies, particularly in response to extreme events. The study results have potential and valuable policy implications for planners and decision-makers regarding infrastructural development and ensuring environmental stability. The study recommends further research to understand how flash flood hazards correlate with changes at different land use/cover (LULC) classes. This could refine flash flood hazards results and maximize its effectiveness.