PCOS-related Infertility Research Articles

Utility of screening for other causes of infertility in women with “known” polycystic ovary syndrome

We investigated the prevalence of abnormal screening results (questionnaire and testing for other causes of oligo-ovulation, male or tubal factor infertility) in a group of 1,313 oligo-ovulatory women (included and excluded subjects) whose condition was screened for inclusion in the Pregnancy in Polycystic Ovary Syndrome trial, a multicenter clinical trial that was conducted at 13 sites in the United States. Other than failure to demonstrate laboratory evidence of hyperandrogenemia, the most common reasons for subject exclusion were persistent oligospermia and tubal factor infertility.

Preimplantation genetic diagnosis of embryos produced from in vitro matured (IVM) oocytes.

Objective: To undergo preimplantation genetic diagnosis (PGD) procedure, the women partner has to undergo in vitro fertilization (IVF) to obtain sufficient number of embryos so that after the genetic test there are enough unaffected embryos left for transfer. Recently, advances have been made to treat women with PCOS-related infertility by in vitro maturation (IVM) technique without stimulating the ovaries with fertility drugs. The main objective of this study was to investigate whether enough oocytes can be retrieved from PCO patients to perform PGD on embryos produced by IVM procedure.