Abstract —The Tuva segment of the Central Asian Orogenic Belt is characterized by the ubiquitous presence of conglomerates few tens of meters to a kilometer in thickness in early Paleozoic volcanosedimentary sequences. We present the first results of geochemical, isotopegeochemical (Sm–Nd and Rb–Sr), and U–Pb geochronological studies of granitoid boulders and pebbles from the conglomerate sequence of the early Cambrian Bayan-Kol Formation of the Systyg-Khem depression. These studies made it possible to establish several sources of clastic material as a result of the destruction of granitoids of different ages and isotope-geochemical compositions. At least two complexes of granitoids were denuded in the pre-Ediacaran tectonic block in the early Cambrian: (1) middle Ediacaran (~590 Ma) and (2) early Ediacaran (~630 Ma); the latter resulted from the melting of pre-Ediacaran island arc crust formed from a depleted mantle source (εNd(T) = +8.0 to +8.6). At present, no granitoids of this age and with such isotope-geochemical characteristics have been found within the Tuva segment. Probably, the granitoid complexes reconstructed from the results of study of clastic conglomerates are eroded or buried beneath younger deposits and do not expose. Thus, the study of clastic conglomerates from the Bayan-Kol Formation provided the first information about the Precambrian history of the tectonic block whose destruction led to the accumulation of this terrigenous sequence.