Crack sealing is an important preventive treatment in the pavement preservation program. To achieve a cost-effective crack seal, it is crucial to select a proper crack sealing method. In Minnesota asphalt pavement cracks are sealed using both the clean-and-seal and rout-and-seal methods; however, there is no guideline for choosing the most suitable crack sealing method. This study deals with a literature review, an online survey, crack seal performance data collection, cost-effectiveness analysis of the crack sealing methods, life cycle cost analysis, and development of two decision trees to aid in selecting the most suitable crack sealing method. The first, which can be used in the pavement management system, needs information such as crack severity, pavement type (new versus overlay), pavement analysis period and design life, traffic level, and crack seal sequence (first, intermediate, or last). The second decision tree, which is a simplified version of the first and can be used by preventive maintenance crews, requires less information, such as crack severity, traffic level, and place in the crack sealing sequence.