Motion capture technology has become integral in studying gait patterns among runners to understand their implications for injury risks. This review synthesizes current literature to examine methodologies and findings related to using motion capture technology for gait analysis in runners. A systematic search was conducted across major academic databases to identify relevant studies published in peer-reviewed journals and conference proceedings. Inclusion criteria focused on studies utilizing motion capture technology to assess biomechanical factors associated with running-related injuries.The review highlights key biomechanical parameters analyzed through motion capture, including joint angles, forces, and muscle activations during running. Studies consistently report on the relationship between gait abnormalities and various injuries such as stress fractures, patellofemoral pain syndrome, and Achilles tendonitis. Practical implications for injury prevention strategies are discussed including personalized gait assessments, targeted interventions such as gait retraining, and advancements in footwear design aimed at optimizing running mechanics and reducing injury risks. Motion capture technology offers a robust platform for advancing our understanding of gait mechanics in runners and their impact on injury prevention. Future research directions should focus on standardizing methodologies, integrating multi-modal data, and applying findings to enhance clinical practice and athletic performance.