Defensive Patterns Research Articles

China, India and the contest for the Indo-Pacific

PurposeThe purpose of this paper is to describe how China’s rapid growth and increasing resource dependence have changed its relationship with India and their respective defense strategies. In particular, we consider China's Belt and Road Initiative, India's “Act East” policy and the strategic and economic value of the Indian Ocean and South China Sea regions.Design/methodology/approachThe authors find no econometric evidence of interactions between China and India’s military spending using a Richardson-Baumol arms race model. Likewise, in a cross-county panel data study of military spending, they find that China’s military spending has no independent effect on military spending in other countries. The authors also show that once wage costs and other sources of military inflation are accounted for, the pattern of real defense spending growth is much less intense than is suggested by nominal data. Nevertheless, they show that China has been undertaking intense military modernization with rapidly rising capital-labor ratios in its defense spending.FindingsThe authors find little evidence of a traditional arms race, but also show that China, and to a lesser extent India, have been realigning their military capabilities to these new security risks while maintaining overall military burden on the economy.Research limitations/implicationsEconometric analysis is limited by data availability and is necessarily historical, whereas the security situation is very fluid and may change in the short term.Practical implicationsThe paper identifies factors that are likely to influence China and India's attitudes to defense spending in the coming years.Social implicationsThe paper finds that there is not an arms race in the traditional sense but may be an arms race in terms of new technologies and military modernization.Originality/valueThis is a very much underexplored topic in economics. The authors take an interdisciplinary approach showing how economics tools can be used to help understand this important issue in international relations.

Transference Neurosis Revisited: The Case of the Emotionally Frozen Woman With Help From Davanloo, Saint Paul and Dickens’ Estella

ABSTRACT The most destructive psychological structures are made all that more lethal by their invisibility. This article explores one such structure, transference neurosis. Transference neurosis occurs when an individual is infected by the neurosis of another person, thus altering the normal defense patterns and causing a distortion in the unconscious. The therapeutic journey is charged with the task of addressing the primary injury as well as the foreign structure within the unconscious. The article will utilize the wisdom of Saint Paul, Charles Dickens, Sigmund Freud, Habib Davanloo and a case vignette in an effort to unmask and treat this destructive force.

Extracts from cultures of Pseudomonas fluorescens induce defensive patterns of gene expression and enzyme activity while depressing visible injury and reactive oxygen species in Arabidopsis thaliana challenged with pathogenic Pseudomonas syringae.

We evaluated the ability of metabolic elicitors extracted from Pseudomonas fluorescens N21.4 to induce systemic resistance (ISR) in Arabidopsis thaliana against the pathogen Pseudomonas syringae DC3000. Metabolic elicitors were obtained from bacteria-free culture medium with n-hexane, ethyl acetate and n-butanol in three consecutive extractions. Each extract showed plant protection activity. The n-hexane fraction was the most effective and was used to study the signal transduction pathways involved by evaluating expression of marker genes of the salicylic acid (SA) signalling pathway (NPR1, PR1, ICS and PR2) and the jasmonic acid/ethylene (JA/ET) signalling pathway (PDF1, MYC2, LOX2 and PR3). In addition, the level of oxidative stress was tested by determining the activity of enzymes related to the ascorbate-glutathione cycle. N-hexane extracts stimulated both pathways based on overexpression of ICS, PR1, PR2, PDF1 and LOX2 genes. In addition, activity of the pathogenesis-related proteins glucanase (PR2) and chitinase (PR3), lipoxygenase and polyphenol oxidase was enhanced together with an increased capacity to remove reactive oxygen species (ROS). This was associated with less oxidative stress as indicated by a decrease in malondialdehyde (MDA), suggesting a causative link between defensive metabolism against P. syringae and ROS scavenging.

Mature Defense Mechanisms Affect Successful Adjustment in Young Adulthood-Adjustment to Military Service in South Korea.

ObjectiveA defense mechanism is an automatic psychological process necessary for successful adaptation. It reflects adaptive capacity. The purpose of this study is to explore the relationship between the adaptation ability of individuals who face mandatory military service and the pattern of defense mechanisms. MethodsThe subjects were 69 men (21.4±2.2 years) who expressed psychological difficulties in three military service situations. Control group was 36 men (24.0±1.4 years) who had successfully completed military service. We examined psychiatric history, the pattern of defense mechanisms, and depression and anxiety levels. Defense mechanisms were compared between two groups. ResultsThe maladjusted group used immature defenses more frequently than the control group did. There were no differences in the defense patterns according to diagnosis. The control group used more identification and rationalization, classified as immature defenses. The temporarily maladjusted group used more somatization, regression, and avoidance. ConclusionUsing mature defense mechanisms helped young adults to adapt to a particular situation. The maturity of the defense is more valuable than the psychiatric diagnosis. Some immature defenses are also helpful to adapt. We cautiously assume that some defenses can be protective or risk factors in adapting to stressful situations by young adults.

Efficient Provisioning of Security Service Function Chaining Using Network Security Defense Patterns

Network functions virtualization intertwined with software-defined networking opens up great opportunities for flexible provisioning and composition of network functions, known as network service chaining. In the cloud, this allows providers to create service chains tuned to each application type while optimizing resources’ utilization. This is particularly useful to accommodate different tenants’ applications with different security needs. However, considering security provisioning from the single perspective of resources optimization may lead to deployment solutions that do not comply with well-known security-related best practices and recommendations. In this paper, we propose network security defense patterns (NSDP) aimed at leveraging the best practice and know-how from the security experts and at capturing various security constraints to efficiently select compliant security functions’ deployment options. The placement problem being a NP-Hard problem to solve, we also propose a scalable networking and computing resources aware optimization framework to efficiently provision different NSDPs. We further show the feasibility of implementing NSDPs in the cloud infrastructure through the integration of our approach into an open source cloud framework, namely OpenStack, in our test laboratory. The simulation results show the effectiveness of our approach in selecting an optimal placement of the security functions for large data centers with hundreds of thousands of computing nodes, while complying with the predefined security constraints and improving the scalability compared to the current placement algorithms.

Defensive patterns in reflective group supervisions at Child Health Centres.

Reflective group supervision with infant healthcare workers has been described in several publications. It aims to enhance their ability to help distressed families, and to comprehend and relieve themselves of the distress that they encounter in such work. The ultimate aim has been formulated as an effort at increasing the professional's reflective function. The present article adds to the literature by applying an ego-psychological perspective on the group process and investigating defensive patterns in such supervisions. This approach includes a critical discussion of the place of the reflective function concept in psychoanalytic metapsychology. The article also suggests a Bionian perspective to account for skewed communicative patterns in groups, so-called basic assumptions. Some technical recommendations are provided on the frame in group supervision. They aim to disarm such defenses and facilitate the group participants' possibilities of understanding and thus helping their colleague's problematic relationship with the family. To illustrate the discussion, and to help readers form an image of the supervision process, brief detailed accounts of such work are submitted.

Hands Up! Atypical Defensive Reactions in Heavy Players of Violent Video Games When Exposed to Gun-Attack Pictures.

Threatening cues and surrounding contexts trigger specific defensive response patterns. Posturography, a technique for measuring postural strategies, has been used to evaluate motor defensive reactions in humans. When exposed to gun pointed pictures, humans were shown to exhibit an immobility reaction. Short and long-term exposure to violent video games was shown to be a causal risk factor for increased violent and aggressive behavior. Assaultive violence with a gun is a major trigger for motor defensive reactions, and post-traumatic stress disorder (PTSD) is the most characteristic psychiatric sequelae. Recent studies point to links between PTSD symptoms and emotional shortfalls in non-clinical trauma-exposed samples. The present study investigated defensive reactions to gun threat and PTSD symptoms in heavy players of violent video games compared to non-players. Male university students were screened according to use of violent video games and divided in three groups: non-players, moderate players, and heavy players. Stimuli were pictures depicting a man pointing a gun directed at the participant. In matched control pictures, non-lethal objects replaced the gun. Posturography was recorded and PTSD symptoms were assessed. When exposed to the threat pictures, non-players exhibited the expected reduction in amplitude of body sway (immobility), heavy players presented atypical augmented amplitude of body sway, and moderate players showed intermediate reactivity. Heavy players presented a significant distinct reaction compared to non-players. They also scored significantly higher in PTSD symptoms than non-players. Disadvantageous defensive reactions and higher vulnerability to PTSD symptoms, revealed in the present study, add to other shortcomings for heavy players.

Design and validation of an observational instrument for defence in soccer based on the Dynamical Systems Theory

The research about soccer defensive phase shows many limitations regarding the procedures and operational definitions. The aims of this paper are to create an observational instrument based on Dynamic Systems concepts and evidence sufficient content validity to adequately and reliably recode defensive soccer behaviours. For these, a five-stage development process for validity was followed: (1) an initial literature review, instrument development, observation training; (2) adapting an existing systematic observational instrument; (3) pilot study with non-experts; (4) content validity with experts (coaches and researchers) and (5) inter- and intra-observer reliability. Using Aiken’s V coefficient and its cut-off value to determine validity content, consensus was found ( V > 0.67, n = 32, p < 0.05) for all items answered by participants in pilot study and for almost all subjects in the experts’ study ( V > 0.69, n = 12, p < 0.05). Also, Cohen’s Kappa shows inter- and intra-reliability values of 0.87 and 0.90, respectively. The final model, entitled Theoretical Dynamic Model of Soccer Defence, and the observational instrument, named Soccer-Defence, with 14 criteria and category systems, and 106 categories, seems to be suitable for analysing the defensive process in soccer and could be used to find strengths or weaknesses of tactical–technical defensive patterns of play and to help coaches to better prepare their teams.

Comparative advantage as a success factor in football clubs: Evidence from the English Premier League (EPL)

As in international trade, football clubs can benefit more if they specialize in what they have or can create comparative advantage. In a world of scarce resources, clubs need to identify what makes them successful and invest accordingly. The main objective of this study is to understand what influences the success of football teams in the English Premier League (EPL) championship games. Based on Ricardo’s model of comparative advantage and applying Factor analysis as well as Panel data approach, this study investigates the need for specialization and tradeoffs between defensive and offensive patterns of the game in order for EPL clubs to be more successful. The data used in this study covers the period 2010-2017 of the EPL data. The results reveal that, in general, a better defense is slightly more important for success. The outcomes were different for the top- and bottom-ranking clubs. We found that it is more important for bottom-ranking teams to play better defensively than offensively, while for top-performing teams, the probability of success is more affected by offensive style. In addition, there is a tradeoff between these two styles of play; when bottom-ranking teams try to play better defensively, it often comes at the expense of a poor offensive pattern, but almost no one plays offense at the expense of a poor defense. Unlike the bottom-ranking teams, the top-ranking teams did not face tradeoffs, but they were able to improve both their defensive and offensive patterns. The recommendation put forward by this study argue that bottom-ranking clubs should specialize first in defense.

Defensive interactions in soccer small-sided games: an integrated approach between the fundamental tactical principles and the social network analysis

This study aimed to 1) present a new analysis of the interactions between the tactical principles of defensive coverage and delay using the Social Network Analysis (SNA); 2) compare the defensive cooperation patterns presented by players of different categories during a 3vs.3 soccer small-sided games SSG; 3) compare the level of defensive prominence presented by defenders, midfielders, and forwards in 3vs.3 SSG within and between different categories. Twenty-eight soccer athletes from U-13 (n=14) and U-14 (n=14) categories of a sports club performed 3vs.3 SSG for the analysis of the defensive tactical principles. Defensive interactions were considered successful defensive coverage and a delay actions performed within the same time interval. Macro (density and clustering coefficient) and micro (degree centrality, degree prestige and page rank) analyses were used as SNA measures. Results indicated no significant differences between categories for the macro and micro analyses. Only in the U-14 category, midfielders presented higher prominence levels than the other playing positions (p=0.004). We concluded that U-13 and U-14 athletes are not different regarding defensive cooperation patterns. A higher positional tactical knowledge obtained through deliberate practice is essential to induce different defensive interactions between playing positions, as shown by significant differences only in the U-14 category.

Evaluating the cyclic ratio schedule as an assay of feeding behaviour in the European starling (Sturnus vulgaris).

The cyclic ratio (CR) schedule is a behavioural assay developed to study feeding in rats, in which the number of operant responses required to obtain food reward (the ratio requirement) increases and then decreases in a repeating cycle. In a recent study, we used the CR schedule with European starlings (Sturnus vulgaris) to investigate the effects of an early-life manipulation on adult feeding behaviour. As this was the first time the CR schedule had been used with any bird species, a more in-depth evaluation is warranted. Here, we performed a fuller CR experiment with the same birds as the prior study, a year later. First, we examine the individual consistency of feeding behaviour between experimental sessions and also between CR schedules comprising different ratio requirement progressions. We found that between-session consistency was poor to moderate, and that a geometric ratio progression provided greater between-session consistency than an arithmetic ratio progression. Second, we tried to replicate some of the canonical findings from rats working on CR schedules. In contrast to findings from rats, we found that defence of feeding rates did not increase when starlings were acutely food deprived. However, as in rats, we found that the post-reinforcement pause increased linearly with the upcoming ratio requirement, suggesting that starlings were able to learn the cyclic nature of the schedule. Third, we compared the results from the present study concerning the impacts of our early-life treatment with those from our earlier study. We found that the majority of our previous findings were replicated in the same individuals one year on, reinforcing our previous conclusion that the early-life manipulation had canalised our birds into two groups with different patterns of feeding rate defence.

Transcriptome analysis of the critically endangered Dabry's sturgeon (Acipenser dabryanus) head kidney response to Aeromonas hydrophila

Dabry's sturgeon (Acipenser dabryanus), as a living fossil, is considered a critically endangered aquatic animal in China. To date, the immune system of this species remains largely unknown, with limited available sequence information. In addition, increasing incidence of bacterial pathogenic diseases has been reported. Hence, the present study aimed to characterize comprehensively transcriptome profile of the head kidney from Dabry's sturgeon infected with Aeromonas hydrophila using Illumina platform. Over 42 million high-quality reads were obtained and de novo assembled into a final set of 195240 unique transcript fragments (unigenes), with an average length of 564 bp. Approximately 41702 unigenes were annotated in the NR NCBI database. Dabry's sturgeon unigenes had the highest number of hits with 14365 (34.45%) to Lepisosteus oculatus. The 195240 unigenes were assigned to three Gene Ontology (GO) categories: biological process, cellular component, and molecular function. Among them, 27770 unigenes were clustered into 26 Eukaryotic Orthologous Group (KOG) functional categories, and 36031 unigenes were mapped to 335 known Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways. After A. hydrophila administration, 1728 differentially expressed unigenes were identified, including 980 upregulated and 748 downregulated unigenes. Further KEGG enrichment analysis of these unigenes identified 16 immune-related pathways, including the Toll-like receptor signaling pathway, chemokine signaling pathway, complement and coagulation pathway, RIG-I-like receptor signaling pathway, and NOD-like receptor signaling pathway. 20 DEGs were selected and their expression patterns are largely consistent with the transcriptome profile analysis, which clearly validated the reliability of the DEGs in transcriptome analysis. This work revealed novel gene expression patterns of Dabry's sturgeon host defense and contributes to a better understanding of the immune system and defense mechanisms of Dabry's sturgeon in response to bacterial infection. The results provide valuable references for studies in sturgeons that lack complete genomic sequences, and could also be helpful for the analyzing evolution among cartilaginous and teleost fish.

Ambush Predation of Stingless Bees (Tetragonisca angustula) by the Solitary-Foraging Ant Ectatomma tuberculatum

Social insect colonies are high-value foraging targets for insectivores, prompting the evolution of complex colony defensive adaptations as well as specialized foraging tactics in social insect predators. Predatory ants that forage on other social insects employ a diverse range of behaviors targeted at specific prey species. Here, we describe a solitary foraging strategy of the ant Ectatomma tuberculatum, on nest guards of the stingless bee Tetragonisca angustula. We observed multiple instances of E. tuberculatum ambushing and successfully capturing the hovering and standing guards of T. angustula near nest entrances. The unique hovering behavior of the guard caste of this bee species, an adaptation to frequent cleptoparasitism by other stingless bees, may make these guards particularly vulnerable to ground-based, ambush attacks by E. tuberculatum. Likewise, the behavior of the foraging ants appears to adaptively exploit the defensive formations and activity patterns of these bees. These observations suggest an adaptive and targeted predatory strategy aimed at gathering external guard bees as prey from these heavily fortified nests.

The feasibility of an augment reality system to study the psychophysiological correlates of fear-related responses.

BackgroundPrevious studies have successfully used augmented reality (AR) as an aid to exposure‐based treatments for anxiety disorders. However, to the best of our knowledge, none of these studies have measured the physiological correlates of the fear response, relying solely on self‐reports and behavioral avoidance tests.MethodsAs the physiological defensive reactivity pattern impacts on the treatment effectiveness, we tested the feasibility of an AR system integrated in a mobile and wearable device for assessing the psychophysiological mechanisms (heart rate) involved in fear responses in real‐life contexts. Specific phobia was used as a model given its prototypical defensive hyperreactivity toward the feared stimulus (spiders to spider phobics, in the current study).ResultsThe results showed that the stimuli presented using AR were able to induce physiological alterations in the participants, which were specific depending on the stimulus type (fear or neutral) and on the participants’ level of spider fear (phobic and control group). These physiological correlates of the fear response were reflected both in the intensity of heart rate (in relation to the baseline) and in the time needed to react and recover after the stimulus exposure. Finally, we tested a theoretical model that showed that the physiological responses of phobic individuals when facing their phobic stimulus only explained its own data.ConclusionsWe argue in favor of the system's feasibility at capturing and quantifying the physiological dimension of fear‐related responses, which may be of great value for diagnostic and treatment purposes in anxiety disorders, namely specific phobia.

Group Resilience: The Place and Meaning of Relational Pauses

Recent scholarship on resilience has shed light on the processes by which organizations absorb strain and maintain functioning in the face of adversity. These theories, however, often focus on the operational impacts of adversity without accounting for the strain it puts on organizational members and their abilities to work effectively together. We apply a relational lens to better understand how adversity, and the anxiety it triggers in people, affects processes of organizational resilience. This conceptual frame enables us to begin uncovering the relational micro-dynamics underlying the absorption of strain. Drawing on group relations theory, we describe two trajectories of intragroup behavior in which strain, in the form of adversity-triggered anxiety, is either acted out or defused. In the brittle trajectory, group members react to anxiety with defensive patterns that leave them vulnerable to effects of adversity. In the resilience trajectory, groups defuse and mitigate adversity-triggered anxiety through a reflective process we call “a relational pause,” ultimately leaving them strengthened and resilient. We elaborate the model by exploring the potential fragility of relational pauses and likely factors that influence groups’ ability and tendency to enact resilience.

A paradox of latitudinal leaf defense strategies in deciduous and evergreen broadleaved trees

The classical “low latitude–high defense” hypothesis is seldom supported by empirical evidence. In this context, we tested latitudinal patterns in the leaf defense traits of deciduous broadleaved (DB) and evergreen broadleaved (EGB) tree species, which are expected to affect herbivore diversity. We examined the co-occurrence of leaf defense traits (tannin and phenol content, leaf mechanical strength, leaf dry matter content, leaf mass per area, and leaf thickness) in 741 broadleaved tree species and their correlations with species geographical range in East Asian island flora. We discovered contrasting latitudinal defense strategy gradients in DB and EGB tree species. DB species employed chemical defenses (increasing tannin and phenol content) at higher latitudes and physical defenses (softer and thinner leaves) at lower latitudes, whereas EGB tree species exhibited opposite latitudinal defense patterns. The “low latitude high defense” hypothesis included a paradoxical aspect in chemical and physical defense traits across broadleaved tree species. To reconcile paradoxical defense strategies along the latitudinal gradient, we conclude that interactive correlations among leaf traits are controlled by leaf longevity, which differs between DB and EGB tree species.

Larval transcriptomic response to host plants in two related phytophagous lepidopteran species: implications for host specialization and species divergence

BackgroundMost phytophagous insects have morphological, behavioral and physiological adaptations allowing them to specialize on one or a few plant species. Identifying the mechanisms involved in host plant specialization is crucial to understand the role of divergent selection between different environments in species diversification, and to identify sustainable targets for the management of insect pest species. In the present study, we measured larval phenotypic and transcriptomic responses to host plants in two related phytophagous lepidopteran species: the European corn borer (ECB), a worldwide pest of maize, and the adzuki bean borer (ABB), which feeds of various dicotyledons. Our aim was to identify the genes and functions underlying host specialization and/or divergence between ECB and ABB.ResultsAt the phenotypic level, we observed contrasted patterns of survival, weight gain and developmental time between ECB and ABB, and within ECB and ABB reared on two different host plants. At the transcriptomic level, around 8% of the genes were differentially expressed (DE) between species and/or host plant. 70% of these DE genes displayed a divergent pattern of expression between ECB and ABB, regardless of the host, while the remaining 30% were involved in the plastic response between hosts. We further categorized plastic DE genes according to their parallel or opposite pattern between ECB and ABB to specifically identify candidate genes involved in the species divergence by host specialization. These candidates highlighted a comprehensive response, involving functions related to plant recognition, digestion, detoxification, immunity and development. Last, we detected viral, bacterial, and yeast genes whose incidence contrasted ECB and ABB samples, and maize and mugwort conditions. We suggest that these microorganism communities might influence the survival, metabolism and defense patterns observed in ECB and ABB larvae.ConclusionsThe comprehensive approach developed in the present study allowed to identify phenotypic specialization patterns and underlying candidate molecular mechanisms, and highlighted the putative role of microorganisms in the insect-host plant interaction. These findings offer the opportunity to pinpoint specific and sustainable molecular or physiological targets for the regulation of ECB pest populations.

A Sociopolitical Ecofeminist Reading of Selected Animal Poems by Elizabeth Bishop

This article examines the sociopolitical vision of some of Elizabeth Bishop’s poems from an ecofeminist critical perspective. Bishop, a twentieth-century American poet, uses animals and natural elements to manifest her attachment to nature (and women by implication), thus reflecting an oppressed feminist voice through the theme of abused, weak nature. By relating Bishop’s poems to W. B. Yeats’s poem Leda and the Swan, we foreground an ecofeminist relation between the Greek myth Yeats employed and Bishop’s poems. Our contribution lies in the multilayered pattern of ecofeminist defense this article traces in poems like Giant Snail, Giant Toad, Strayed Crab, The Armadillo, Sandpiper, The Moose and Trouvée. The conclusion emphasizes the attempts Bishop shoulders through her animal poetry to renew the old man-nature relation of balance and justice and simultaneously to elevate woman/nature. Bishop's poetry, it is argued, exceeds the personal or subjective and thus contains socio-political, anti-patriarchal thrusts explored in this article through an ecofeminist lens.

Dynamics of Defensive Response Mobilization to Approaching External Versus Interoceptive Threat

BackgroundExcessive fear and anxiety are core features of anxiety disorders. Defensive response mobilization varies dynamically with threat proximity. MethodsWe analyzed defensive responses in 48 healthy students to an approaching external, predator-like threat (an electric shock resembling a predator attack) versus an approaching threat from inside the body (feeling of dyspnea as evoked by forced breath-holding). Threats either were inevitable or could be avoided by button press. ResultsAutonomic changes (heart rate, skin conductance), defensive reflex priming (startle eyeblink response), respiratory responses, and event-related potentials were assessed. Regardless of its source, when an approaching threat was inevitable, a defensive pattern emerged characterized by an increase in skin conductance, a potentiation of the startle reflex, and bradycardia. Minute ventilation increased only with approaching dyspnea. In preparation for active avoidance of either threat, startle magnitudes were inhibited and probe-elicited P3 wave amplitudes were reduced. Moreover, generation of avoidant action resulted in heart rate acceleration. ConclusionsThis study demonstrates common and specific defensive activation patterns for approaching external and respiratory threats. The specific modulation in respiration in response to an inevitable respiratory threat may have important implications for our understanding of the etiology of anxiety disorders, especially panic disorder.

Similar effect of CRF1 and CRF2 receptor in the basolateral or central nuclei of the amygdala on tonic immobility behavior

Studies have used paradigms based on animal models to understand human emotional behavior because they appear to be correlated with fear- and anxiety-related defensive patterns in non-human mammals. In this context, tonic immobility (TI) behavior is an innate response associated with extreme threat situations, such as predator attack. Some reports have demonstrated the involvement of corticotropin-releasing factor (CRF) in regulation of the endocrine system, defensive behaviors and behavioral responses to stress. Particularly, a previous study showed that the activation of CRF receptors in the basolateral (BLA) or central (CeA) nuclei of the amygdala increased TI responses, whereas treatment with a non-selective CRF antagonist, alpha-helical-CRF9-41, decreased this innate fear response. However, while CRF1 receptors have pronounced effects in stress-induced anxiety, CRF2 receptors appear be involved in the expression of both stress-induced anxiety and spontaneous anxiety behavior. In this study, we investigated the effects of specific CRF receptors, CRF1 and CRF2, in the BLA and CeA on the duration of TI in guinea pigs. The results show that blockade of CRF1 and CRF2 receptors in the BLA and CeA produces a decrease in fear and/or anxiety, as suggested by a decrease in TI duration in the guinea pigs. Additionally, the specific antagonists for CRF1 and CRF2 receptors were able to prevent the increase in TI duration induced by CRF administration at the same sites. These results suggest that the modulation of fear and anxiety by the CRF system in the BLA and CeA occurs through concomitant effects on CRF1 and CRF2 receptors.