Nutritional Status Of Patients Research Articles

The Association of Altered Sense of Smell with Nutritional Status in Patients with Advanced CKD

The Association of Altered Sense of Smell with Nutritional Status in Patients with Advanced CKD

Assessing Nutrition Status in an Outpatient Wound Center: A Feasibility Study.

To explore the feasibility of using the Patient-Generated Subjective Global Assessment (PG-SGA) to assess the nutrition status of patients with chronic wounds receiving care in an outpatient wound clinic. The PG-SGA was administered to a single cohort convenience sample of adults with chronic wounds who presented to an outpatient wound clinic. The authors performed univariate descriptive analyses and calculated interrater reliability. Nutrition assessments were completed with 15 clinic patients. Patients required an average of 6.5 minutes (range, 3.5-10 minutes) to complete their component of the PG-SGA, exceeding the target goal of 5 minutes or fewer. Dietitians required an average of 2 minutes per patient to complete the professional component of the PG-SGA (physical examination). The nutrition assessment process was rated highly favorable. Resources to conduct the study at the site were available 100% of the time. The PG-SGA demonstrates promise for use in the chronic wound population and could be incorporated into clinical care in settings equipped with appropriate and adequate resources. The complexities of workforce stability and resource availability, in addition to the ongoing need to be responsive to patient challenges, must be acknowledged in the planning of future studies.

The Assessment of Vascular Calcification, Arterial Stiffness, and Nutritional Status in Patients on Hemodialysis, A 5-Year Follow-up Study

The Assessment of Vascular Calcification, Arterial Stiffness, and Nutritional Status in Patients on Hemodialysis, A 5-Year Follow-up Study

Sarcopenic Dysphagia and Simplified Rehabilitation Nutrition Care Process: An Update.

Sarcopenic dysphagia is characterized by weakness of swallowing-related muscles associated with whole-body sarcopenia. As the number of patients with sarcopenia increases with the aging of the world, the number of patients with sarcopenic dysphagia is also increasing. The prevalence of sarcopenic dysphagia is high in the institutionalized older people and in patients hospitalized for pneumonia with dysphagia in acute care hospitals. Prevention, early detection and intervention of sarcopenic dysphagia with rehabilitation nutrition are essential. The diagnosis of sarcopenic dysphagia is based on skeletal and swallowing muscle strength and muscle mass. A reliable and validated diagnostic algorithm for sarcopenic dysphagia is used. Sarcopenic dysphagia is associated with malnutrition, which leads to mortality and Activities of Daily Living (ADL) decline. The rehabilitation nutrition approach improves swallowing function, nutrition status, and ADL. A combination of aggressive nutrition therapy to improve nutrition status, dysphagia rehabilitation, physical therapy, and other interventions can be effective for sarcopenic dysphagia. The rehabilitation nutrition care process is used to assess and problem solve the patient's pathology, sarcopenia, and nutrition status. The simplified rehabilitation nutrition care process consists of a nutrition cycle and a rehabilitation cycle, each with five steps: assessment, diagnosis, goal setting, intervention, and monitoring. Nutrition professionals and teams implement the nutrition cycle. Rehabilitation professionals and teams implement the rehabilitation cycle. Both cycles should be done simultaneously. The nutrition diagnosis of undernutrition, overnutrition/obesity, sarcopenia, and goal setting of rehabilitation and body weight are implemented collaboratively.

Analysis of Energy and Protein Intake with Nutritional Status of Chronic Kidney Failure Patients with Hemodialysis at Harapan and Doa Regional Hospital, Bengkulu City

Background:Chronic kidney disease is a global public health priority that continues to grow and is associated with high morbidity rates and is the third fastest growing cause of death in the world and the fifth leading cause of death. Malnutrition often occurs in end-stage renal disease patients undergoing hemodialysis (HD). Malnutrition is caused by catabolic events during the hemodialysis process. Objective: The aim of the study was to analyze energy intake, protein and nutritional status of chronic kidney failure patients on hemodialysis at Harapan and Doa Regional Hospital, Bengkulu City. Materials/Methods: Explanatory research type, with a cross sectional approach. The study population was all chronic kidney failure sufferers who underwent hemodialysis at Harapan and Doa Hospital, Bengkulu City in June-July 2023. Data were collected by interviews and anthropometric measurements, 3x24 hour recall forms and SGA forms and from patient medical records. Data processing was carried out using univariate tests. Result:This study shows that 98% of respondents' energy intake before hemodialysis had insufficient energy intake (< 80%) and 2% had sufficient energy intake (80), protein intake before hemodialysis 92% protein intake is less (< 80%) during hemodialysis and after hemodialysis 85% with less protein intake (< 80%), nutritional status of chronic kidney failure patients with hemodialysis good nutritional status (SGA score A), namely (54%) lack of protein intake, poor/moderate nutritional status (SGA B score), namely (43%), poor nutritional status (SGA C score), namely (3%). Conclusion:The conclusion of this study is that energy intake, protein and nutritional status in chronic kidney failure patients on hemodialysis are still lacking. Therefore, increasing intake needs to be done by paying attention to the patient's nutritional status

Evaluation of the Role of Dentures & Dietary Advice on Nutritional Status of Complete Edentulous Patients Using MNA®-SF: An Observational Study.

Aim This study aims to evaluate the role of dentures and dietary advice on the nutritional status of complete edentulous patients using the mini nutritional assessment-short form (MNA®-SF). Objective The objective of this study is to assess patients' nutrition using MNA®-SF before denture insertion and nutritional advice, to evaluate patients' nutrition usingMNA®-SF after denture insertion and nutritional advice at one month and three months, and to assess and compare pre- and post-insertion differences in nutrition usingMNA®-SF. Material and Method An observational study was conducted among 50 completely edentulous patients using theMNA®-SFquestionnaire. They were asked the questions at baseline and then after they were given complete dentures, after which they were recalled after one month and three months to assess the nutritional status usingMNA®-SF. All the questions were in the native language, so it was easy to understand the question and respond to it. Result It was found that the patient's nutritional status had significant changes, which shows that the dietary advice and complete denture affected the patient's nutritional status. Conclusions This study helped assess the efficacy and application ofMNA®-SFin completely edentulous patients. In this study, we provided nutritional guidance to patients in addition to complete denture prostheses to encourage them to have healthy eating habits.

Assessment of Nutritional Status Using SGA (Subjective Global Assessment) and MIS (Malnutrition Inflammation Score) Tools in Hemodialysis Patients

Introduction: One of the problems often found in patients undergoing hemodialysis is changes in their nutritional status. Patients with hemodialysis who are malnourished have a higher risk of disease and death. This nutritional disorder can be overcome by assessing nutritional status. Apart from using the SGA (Subjective Global Assessment) method, the MIS (Malnutrition Inflammation Score) method can also be used. The aim of this study was to compare differences in nutritional status of patients on hemodialysis using the SGA and MIS instruments. Methods: This research was a quantitative research with a cross-sectional design. The research sample consisted of 75 patient with hemodialysis at one of military hospital, who were selected using non-probability techniques with a total sampling approach. The statistical test used is the Mann-Whitney test with level of significance 0.05 to compare differences between variables. Results: Using the SGA tool, it was found that more than half of respondents (66.7%) were in the moderate nutrition category, while only 9.3% were in the malnutrition category. In contrast, with MIS tools, it was found that 34.7% were in the mild malnutrition and not malnourished category, while 65.3% were in the moderate to severe malnutrition category. Furthermore, statistical analysis shows that there is a significant difference (p = 0.001) between the use of SGA and MIS in assessing nutritional status in patients with hemodialysis. Conclusion: It can be concluded that there is a difference between the use of SGA and MIS in assessing nutritional status in patients with hemodialysis. Further research, could explore more for the advantages and disadvantages of each instrument, including the level of accuracy and sensitivity.

Clinical Efficacy of Tongxinluo Capsule Combined with Nutritional Support on Coronary Heart Disease Angina Pectoris

This study aimed to explore the impact of the Tongxinluo capsule combined with nutritional support on the clinical efficacy and nutritional status of patients with coronary heart disease angina pectoris. A total of 118 patients admitted to our hospital between August 2022 and May 2023 were divided into a control group and an observation group. Patients in the control group underwent routine treatment and nutritional interventions. Patients in the observation group received Tongxinluo capsules and tailored nutritional treatments. The observation group had a higher total effective rate, left ventricular ejection fraction, and high-density lipoprotein cholesterol level than the control group. Conversely, it had lower left ventricular end-systolic diameter, left ventricular end-diastolic diameter, total cholesterol, triglyceride, and low-density lipoprotein cholesterol levels compared to the control group. Interleukin-6, tumor necrosis factor α, hypersensitive C-reactive protein levels, plasma viscosity, hematocrit, high-cut whole blood viscosity, fibrinogen level, and body mass index of the observation group were also lower than the control group. The incidence of adverse reactions between the two groups was not significant (P > 0.05). Tongxinluo capsule, combined with nutritional support effectively and safely treats coronary heart disease angina pectoris and can improve patients’ cardiac function index.

Impact of Postoperative Naples Prognostic Score to Predict Survival in Patients with Stage II-III Colorectal Cancer.

The Naples prognostic score (NPS) is a scoring system that reflects a patient's systemic inflammatory and nutritional status. This study aimed to evaluate whether postoperative NPS is effective in assessing the prognosis of stage II-III colorectal cancer (CRC) patients compared with preoperative NPS. Between 2005 and 2012, a total of 164 patients diagnosed with stage II-III CRC, who underwent curative resection followed by adjuvant chemotherapy, were divided into two groups: Group 0-1 (NPS = 0-2) and Group 2 (NPS = 3 or 4). Preoperative NPS was calculated based on the results before surgeries, and postoperative NPS was assessed using the results obtained before adjuvant chemotherapy. The overall survival of Group 0-1 was higher than that of Group 2 in both pre- and postoperative NPS assessments. According to the ROC curve analysis, the Area Under the Curve (AUC) ratio for postoperative NPS was 0.64, compared with 0.57 for preoperative NPS, 0.52 for the preoperative neutrophil-lymphocyte ratio (p = 0.032), and 0.51 for the preoperative platelet-lymphocyte ratio (p = 0.027). Postoperative NPS is effective in predicting the prognosis of stage II-III CRC patients who underwent curative resection followed by adjuvant chemotherapy. The use of NPS could be beneficial in evaluating the prognosis of CRC patients after surgeries.

Naples Prognostic Score for Graft Functions After Renal Transplantation: A Retrospective Analysis.

BACKGROUND The Naples prognostic score is a comprehensive measure of patients' inflammation and nutritional status, consisting of serum albumin, total cholesterol, neutrophil/lymphocyte ratio (NLR), and lymphocyte/monocyte ratio (LMR). We compared the Naples prognostic scores of kidney transplant patients with a creatinine reduction ratio of less than 30% vs those with greater than 30%. MATERIAL AND METHODS We conducted a retrospective study on 93 patients who received kidney transplants at our hospital from January 2020 to January 2023. Naples prognostic scores were used to calculate the preoperative condition of transplant recipients. The patients were divided into 2 groups based on their creatinine reduction ratio on the second day after surgery. Group A consisted of patients with a ratio above 30%, while group B consisted of those with a ratio below 30%. RESULTS Our analysis revealed that the total cholesterol and albumin values of groups A and B showed no substantial difference. Group B had clearly more patients with Naples prognostic score 3-4 compared to the other group (P=0.032). Multivariate analysis determined that patients with Naples prognostic score 3-4 had a 3.151-fold higher likelihood of experiencing creatinine reduction below 30% (95% CI 1.209-8.215, P value 0.019). CONCLUSIONS The preoperative inflammatory and nutritional status of patients may have an impact on the functioning of grafts during the postoperative period. A high Naples prognostic score may be linked with a decrease in creatinine reduction ratio in post-transplant kidneys, which could lead to graft dysfunction.

Progress and Clinical Applications of Crohn's Disease Exclusion Diet in Crohn's Disease.

Crohn's disease is a chronic intestinal inflammatory disorder of unknown etiology. Although the pharmacotherapies for Crohn's disease are constantly updating, nutritional support and adjuvant therapies have recently gained more attention. Due to advancements in clinical nutrition, various clinical nutritional therapies are used to treat Crohn's disease. Doctors treating inflammatory bowel disease can now offer several diets with more flexibility than ever. The Crohn's disease exclusion diet is a widely used diet for patients with active Crohn's disease. The Crohn's disease exclusion diet requires both exclusion and inclusion. Periodic exclusion of harmful foods and inclusion of wholesome foods gradually improves a patient's nutritional status. This article reviews the Crohn's disease exclusion diet, including its structure, mechanisms, research findings, and clinical applications.

Salivary trace elements in patients with ulcerative colitis on different treatment modalities

The nutritional status of patients with inflammatory bowel disease is considered less than ideal. This study aimed to compare the salivary levels of some trace elements (Zinc, copper, and magnesium) in patients with ulcerative colitis (UC) on two different therapeutic modalities to control subjects. Materials and methods: This cross-sectional study was performed in 2021-2022 on 53 diagnosed UC patients (27 UC patients on oral immunosuppressant therapy and 26 UC patients on combination therapy). All subjects were randomly selected from gastroenterology and Hepatology teaching hospitals in Baghdad city; twenty-five subjects were also recruited as controls. Demographic data were recorded through a checklist. Salivary levels of zinc (Zn), copper (Cu) and magnesium (Mg) were measured by atomic absorption spectroscopy. Data were analyzed using SPSS-28 at a significance level of 0.05. The results: Salivary Zn mean was significantly lower in monotherapy and combination therapy patients than in controls (p<0.001). Mean salivary Cu levels were significantly higher in monotherapy and combination therapy patients than in controls (p<0.001). Similarly, the salivary Mg mean was significantly lower in both groups of ulcerative colitis patients than in controls (p<0.001). The mean of salivary Cu was higher in UC patients, while the men of Zn and Mg were lower in UC patients compared to controls. Conclusions: The results showed that UC patients have significantly lower Zn and Mg levels than healthy individuals and were lower inpatient on monotherapy than in combination. At the same time, salivary Cu in UC patients was higher than in control individuals and was higher in UC patients on monotherapy. Keywords: Inflammatory bowel diseases, Ulcerative colitis, Trace elements

Alteration and significance of serum lipid levels and nutritional status during BCMA-CAR-T-cell therapy in patients with refractory or relapsed multiple myeloma: a retrospective study based on LEGEND-2

Objective: To explore the dynamic changes in serum lipid levels and nutritional status during BCMA-CAR-T-cell therapy in patients with refractory or relapsed multiple myeloma (R/R MM) based on LEGEND-2. Methods: The data of patients with R/R MM who underwent BCMA-CAR-T therapy at our hospital between March 30, 2016, and February 6, 2018, were retrospectively collected. Serum lipid levels, controlled nutritional status (CONUT) score, and other clinical indicators at different time points before and after CAR-T-cell infusion were compared and analyzed. The best cut-off value was determined by using the receiver operator characteristic (ROC) curve. The patients were divided into high-CONUT score (>6.5 points, malnutrition group) and low-CONUT score groups (≤6.5 points, good nutrition group), comparing the progression-free survival (PFS) and total survival (OS) of the two groups using Kaplan-Meier survival analysis. Results: Before the infusion of CAR-T-cells, excluding triglycerides (TG), patients' serum lipid levels were lower than normal on average. At 8-14 d after CAR-T-cell infusion, serum albumin (ALB), total cholesterol (TC), high-density lipoprotein (HDL), low-density lipoprotein (LDL), and apolipoprotein A1 (Apo A1) levels dropped to the minimum, whereas CONUT scores reached the maximum. In addition to TG, apolipoprotein B (Apo B) levels increased compared with baseline. After CAR-T-cell therapy, the patients' serum lipid levels significantly increased with well-improved nutritional status. Spearman's related analysis showed that TC, HDL, and ApoA1 levels after CAR-T-cell injection were significantly negatively correlated with the grade of cytokine-release syndrome (CRS) (r=-0.548, P=0.003; r=-0.444, P=0.020; r=-0.589, P=0.001). Furthermore, survival analysis indicated that the CONUT score was unrelated to PFS, and the median OS of patients with R/R MM in the high-CONUT score group was shorter than that in the low-CONUT score group (P=0.046) . Conclusions: During CAR-T-cell therapy, hypolipidemia and poor nutritional status were aggravated, which is possibly related to CRS. The patients' serum lipid levels and nutritional status were significantly improved after CAR-T-cell treatment. The CONUT score affected the median OS in patients treated with CAR-T-cells. Therefore, specific screening and intervention for nutritional status in patients receiving CAR-T-cell therapy are required.

The effect of probiotics on surgical outcomes in patients with gastric cancer: a meta-analysis of randomized controlled trials.

The effect of probiotics on postoperative infectious complications and nutritional status in patients with gastric cancer is still controversial, and a comprehensive search and analysis of the current relevant evidence is necessary. Our study aimed to define the effects of probiotics on surgical outcomes in gastric cancer patients undergoing surgery. Up to June 20, 2023, Embase, PubMed, Web of Science, and Cochrane databases were searched for randomized controlled trials of probiotics in gastric cancer patients undergoing surgery. Relative risk (RR) or mean difference (MD) was used to calculate the effect sizes using RevMan 5.3. A total of nine studies reporting on 861 participants were included. Perioperative supplementation with probiotics did not improve weight loss (MD 0.73 kg; 95% CI: -0.56, 2.02) or serum prealbumin levels (MD 9.48 mg/L 95% CI: -3.43, 22.40), but did reduce the incidence of postoperative infectious complications (RR 0.46, 95% CI 0.28, 0.77), shorten the time to first exhaust (MD -11.27 h; 95% CI: -16.83, -5.70), the time to first defecation (MD -15.71 h; 95% CI: -25.62, -5.79), and the length of hospital stay (MD -0.94 days; 95% CI: -1.33, -0.55), and increase serum albumin levels (MD 0.73 g/L; 95% CI: 0.01, 1.46) in gastric cancer patients undergoing surgery. Probiotics are effective in preventing postoperative infectious complications, promoting postoperative recovery, and improving nutritional status in gastric cancer patients undergoing surgery. Our study highlights the importance of probiotics for healthcare systems and offers a potential strategy to improve the prognosis and reduce the medical burden of gastric cancer patients undergoing surgery.

Alterations of Thyroid Function and Nutritional Status in Patients with Type 2 Diabetes Mellitus Complicated by Metabolic Syndrome Treated with Insulin Combined with Either Liraglutide or Dapagliflozin

The present study compared the effectiveness of insulin plus liraglutide or dapagliflozin in treating type 2 diabetes mellitus complicated with metabolic syndrome and observed the nutritional status of patients before and after treatment. The results revealed no significant difference in the overall clinical efficacy and blood glucose levels between the liraglutide group treated with liraglutide and the dapagliflozin group treated with dapagliflozin (P > 0.05). In contrast, the adverse reactions in the liraglutide group were even lower than those in the control group (P < 0.05). In addition, the liraglutide group demonstrated better improvements in insulin metabolism and blood lipid levels than the dapagliflozin group after treatment. However, their ability to repair thyroid function and alleviate oxidative stress was comparatively weak (P < 0.05). Serum albumin, total protein, and transferrin levels were elevated in both groups after treatment, but the increase in the dapagliflozin group was higher than that in the liraglutide group (P < 0.05). The number of malnutrition cases was significantly reduced in both groups after treatment compared to before treatment (P < 0.05). These results suggest that the combination of insulin with liraglutide or dapagliflozin is highly effective in treating type 2 diabetes mellitus complicated by metabolic syndrome and can effectively improve the nutritional status of patients.

Gambaran Proses Asuhan Gizi Terstandar pada Pasien Penyakit Ginjal Kronik Stadium IV

Background: Chronic kidney disease is a situation where there is a decrease in kidney efficiency which occurs slowly over a long period of time and has remained stable for the last 3 months. Chronic kidney disease patients who are hospitalized are not only given health care, but also given nutritional services in the form of standardized nutritional care. Nutritional care aims to help patients solve nutritional problems by overcoming various factors that cause nutritional status to change or be unbalanced. Research Objective: To describe the process of standardized nutritional care for patients with stage IV chronic kidney disease. Research Method: Observational descriptive method with case studies in patients with stage IV chronic kidney disease. Research Results: The patient on behalf of Mrs. 57 year old R was admitted to hospital with a diagnosis of stage IV chronic kidney disease. From the results of the nutritional assessment, the patient had a low level of consumption of energy, protein, fat and carbohydrates. The results of anthropometric measurements of the patient have good nutritional status. Based on laboratory results, the patient had a high serum creatinine level and the patient's Hb, erythrocyte count, hematocrit, MCH, MCHC examination results were in the low category. The results of the patient's physical and clinical examination were weak and the patient's blood pressure was high. Nutritional diagnoses that can be made include inadequate oral intake, decreased protein and sodium requirements, and changes in laboratory values ​​related to nutrition. The type of diet given is a low protein and low salt diet. The results of monitoring and evaluating the patient's food intake increased to ≥80% on the second day, the patient's nutritional status was good, there were no laboratory developments because the patient did not have another laboratory examination, and the patient's physical and clinical condition was good and the patient's blood pressure was normal. Conclusion: After intervention for 2 days, the results of monitoring and evaluating the patient's food intake increased on the second day, reaching ≥80% for energy, protein and fat. Then, for anthropometric monitoring and evaluation, the patient has good nutritional status. Then, monitoring and evaluating laboratory data could not be carried out because the patient did not undergo another laboratory examination. Furthermore, the results of monitoring and evaluating the patient's physical and clinical condition were good and the patient's blood pressure was normal.

Personalizing electrolytes in the dialysis prescription: what, why and how?

Maintenance hemodialysis patients suffer from multiple comorbidities and treatment-related complications. A personalized approach to hemodialysis prescription could reduce some of these burdens by preventing complications such as excessive changes in blood pressure, arrhythmias, post-dialysis fatigue and decreased quality of life. A patient-centered approach to dialysate electrolyte concentrations represents one such opportunity. In addition to modifications in dialysate electrolyte concentrations, consideration of individual factors such as patients' serum concentrations, medication profiles, nutritional status and comorbidities is critical to tailoring hemodialysis prescriptions to optimize patient outcomes. The development of personalized dialysis treatment depends on the collection of comprehensive patient data, advances in technology, resource allocation and patient involvement in decision-making. This review discusses how the treatment of maintenance hemodialysis patients could benefit from individualized changes in certain dialysis fluid components.

Evaluating the Effectiveness of Ginkgo Biloba Extract in Alleviating Dizziness and Improving Nutritional Status in Cerebral Arteriosclerosis Patients

In this study, we aimed to evaluate the therapeutic efficacy of Ginkgo biloba extract in ameliorating dizziness symptoms and enhancing nutritional status in patients diagnosed with cerebral arteriosclerosis. A total of 170 patients suffering from cerebral arteriosclerosis were selected and divided randomly into two groups: a control group receiving conventional treatment and an experimental group receiving standard treatment plus Ginkgo biloba extract. A comparative analysis revealed that the experimental group demonstrated significant improvement in neurological function and mobility post-treatment, exhibited reduced dizziness symptoms and improved hemodynamics in the vertebral and basilar arteries compared with the control group (P < 0.05). The experimental group exhibited a significantly better nutritional status post-treatment compared with the control group (P < 0.05). To further elucidate the underlying mechanisms of Ginkgo biloba extract’s effects on cerebral arteriosclerosis, a cerebral arteriosclerosis rat model was developed. The results indicated that Ginkgo biloba extract intervention mitigated inflammation and oxidative stress in the brain tissues of rats with cerebral arteriosclerosis, leading to reduced pathological damage. These findings suggest that Ginkgo biloba extract has the potential to relieve cerebral arteriosclerosis-related dizziness and improve nutritional status in patients, offering a promising novel therapeutic modality for the clinical management of cerebral arteriosclerosis.

NUTRITIONAL SUPPORT FOR CANCER PATIENTS IN THE EARLY POSTOPERATIVE PERIOD

Relevance: The modern medicine, evaluating patients’ nutritional status is a priority for many specialists. The incidence of nutritional deficiency in cancer pathology increases annually by 65-85%. The nutritional status of patients is represented by a decrease in life expectancy, deterioration of immediate and long-term treatment results, a decrease in the tolerability of therapy, and a decrease in the quality of life. Early detection of nutritional insufficiency and evaluation of the patient’s nutritional status makes it possible for early provision of nutritional therapy and has a positive effect before the operation, during and after the operating period, reduces postoperative complications, and reduces the duration of stay in the hospital. This article reflects on the features of evaluating the nutritional status and methods of correction of clinical nutrition.
 The study aimed to analyze the effectiveness of cancer patients’ nutrition in the early postoperative period and determine the optimal method of its implementation.
 Methods: We compared the clinical effectiveness of enteral and parenteral nutrition methods in the complex of postoperative therapeutic measures on the hepato-pancreatic-duodenal zone.
 Results: On Days 10-12 after surgery, 12 out of 17 control group patients had normal nutritional status judging by their Subjective Global Assessment (SGA) and Nutritional Risk Index (NRI), and five had moderate malnutrition. After enteral nutrition was added (on Days 13-15), no malnutrition cases in this group were detected. The total blood protein in the subjects showed a significant difference between the average values of indicators in clinical groups for the entire study period (p<0.05). The average total blood protein by Day 8 after surgery was 62.5±10.0 g/L in the leading group and 57.5±10.1 g/L in the control group. The change in the blood biochemical composition was due to the volume, duration, and nature of the surgical intervention.
 Conclusion: When using nutritional therapy in cancer patients operated on for tumors of the hepato-pancreatic-duodenal zone in the early postoperative period, the enteral route of administration of nutrient mixtures is preferred, provided there is no pronounced intestinal paresis and purulent discharge from the stomach.

Early enteral nutrition intervention promotes multiple functional recovery in patients with traumatic intracerebral hemorrhage: A prospective randomized controlled study

ObjectiveTo delve into how early enteral nutrition intervention exert its part in promoting multiple functional recovery in patients with traumatic intracerebral hemorrhage (TICH). MethodThis prospective randomized controlled study recruited 152 traumatic intracerebral hemorrhage patients in our hospital. The observation group (n = 77) received early enteral nutrition intervention (≤ 48 h), while the control group (n = 75) were given delayed enteral nutrition (> 48 h). Further comparison was performed on the recovery of various physiologic functions between the two groups. ResultsAfter treatment, GCS score and GOS score in the observation group were significantly higher than those in the control group (P < 0.05), and mRS Score was significantly lower than that in the control group (P < 0.05). Moreover, the observation group demonstrated a considerable post-treatment elevation in adrenocorticotropic hormone (ACTH) and cortisol (Cor) levels, which were notably higher than the control group's levels (both P < 0.05). The changes in Bifidobacteria, Enterococcus, and Escherichia coli values pre and post-treatment were more remarkable in the observation group (all P < 0.05). Kaplan-Meier survival curve analysis indicated a substantial difference in survival curves between patients who provided with early enteral nutrition and those where it later (P < 0.05). ConclusionThe early application of enteral nutrition can promote neurological function recovery, improve the disorder of intestinal flora and the patient's nutritional status, reduce the increase of injury factors under stress, and lower the mortality risk among patients suffering from TICH.