Patients In Yaounde Research Articles

Dietary Control and Lipid Profiles of Type 2 Diabetes Mellitus Patients in Yaounde, Cameroon

This study was conducted to compare the dietary and blood lipids between type 2 diabetes subjects and non diabetes subjects living in Cameroon. Dietary intakes were significantly higher in non diabetic men compared to diabetic men but not significantly higher in diabetic women compared to diabetic women. Dietary fiber was significantly higher in diabetic men and women compared to non diabetic subjects. Type 2 diabetic patients of both sexes had a triglyceridemia level higher than non diabetic patients. However Type 2 diabetic men had a cholesterolemia level lower than non diabetic men and there was no difference between cholesterolemia of type 2 diabetic women and non diabetic women. It was concluded that type 2 diabetic subjects are consuming diets that are varied and nutritionally adequate for a healthy adult. To optimize nutrition therapy of type 2 diabetic subjects in Cameroon, recommendations should emphasize on traditional dishes which are mainly constitutes of tubers, fruits, cereals and green leaf vegetables.

1272 Stroke in sickle-cell patients in Yaounde

1272 Stroke in sickle-cell patients in Yaounde

Tuberculosis pleural effusion in HIV seropositive and HIV seronegative adult patients in Yaounde, Cameroon

Tuberculosis pleural effusion in HIV seropositive and HIV seronegative adult patients in Yaounde, Cameroon

In vitro activity of antimalarials against clinical isolates of Plasmodium falciparum in Yaounde, Cameroon.

The in vitro activity of nine antimalarials was determined against 119 fresh clinical isolates of Plasmodium falciparum obtained from symptomatic indigenous patients in Yaounde, Cameroon. using the isotopic semimicrotest. Seventy-four parasites were resistant to chloroquine (mean 50% inhibitory concentration [IC50] 337 nM); 45 were chloroquine-sensitive (mean IC50 35.6 nM). Twenty-five of 58 chloroquine-resistant parasites were resistant to monodesethylamodiaquine, the biologically active metabolite of amodiaquine. None of the chloroquine-sensitive isolates was resistant to monodesethylamodiaquine (IC50 17.3 nM). Pyronaridine, quinine, mefloquine, halofantrine, and artemether were highly active against the chloroquine-sensitive and the chloroquine-resistant isolates. Of the 43 isolates tested, 25 were sensitive to both pyrimethamine and cycloguanil, the biologically active metabolite of proguanil. The in vitro responses of chloroquine and monodesethylamodiaquine, chloroquine and quinine, quinine and mefloquine, mefloquine and halofantrine, artemether and mefloquine or halofantrine, and pyrimethamine and cycloguanil were significantly correlated. The present study suggests that chloroquine resistance is highly prevalent in vitro in Yaounde and that the alternative drugs are generally highly active against the chloroquine-resistant parasites.