<p class="AbstractContent"><strong>Objective:</strong> Type 2 diabetes mellitus (type 2 diabetes) is a chronic disease that requires long-term management throughout the life to prevent acute and chronic complications. Self-care is a fundamental and integral part of diabetes management. Social support obtained from family, health professionals, friends, or diabetic peers may predict good self-care behavior. The purpose of this study was to evaluate the self-care behavior of adult with type 2 DM in Persadia Depok.</p><p class="AbstractContent"><strong>Methods: </strong>This quantitative study used a cross-sectional design. A consecutive sample of 52 subjects with type 2 DM who joined in Persadia Depok was included. The instrument used to measure self-care behavior is The Summary of Diabetes Self-Care Activities questionnaire</p><p class="AbstractContent"><strong>Results:</strong> The results showed that self-care behavior of participants in the last seven days is 4,4 days (Median 4.4, Minimal-Maximum 2.6-5.4, 95% CI 4.1-4.5). Self-care was described as “good” in only half of the participant (50%). Self-care behavior was reported good in diet, physical exercise, and taking medication, but it was poor in self-monitoring of blood glucose (SMBG) and foot care.<strong></strong></p><p><strong>Conclusion: </strong>This study recommended that nurses should enhance education and support to improve patient self-care behaviors especially SMBG and foot care.</p><p class="AbstractContent"><strong> </strong></p><p><strong>Keywords: </strong>Colon cancer, deep breathing, early mobilization, effective coughing, preoperative education.</p>