Abstract Objectives This presentation will describe our experience implementing and utilizing whole-slide imaging (WSI) as a teaching tool for the pathology residents in Henry Ford Hospital, Detroit, as well as our initial efforts to use WSI at institutional tumor boards. Methods Glass slides were scanned for practice over several weeks to determine basic operation, system performance, and workflow processes. Experience quickly showed that the scanner could be used to improvement quality and efficiency of weekly unknown slide conference. Informatics lecture and luncheon meeting topics as well as a grand-rounds presentation on novel ways to use WSI were shared with residents and other members of the department. This resulted in marked increased interest. Soon interest grew from attending physicians to use WSI for a subset of tumor boards. The same processes and procedures used for scanning slides for unknown conference were applied. Results In October 2016, an unknown slide conference was presented using WSI. The reaction to the quality of the histopathology system usage was excellent: nuclear contours and nucleoli were clear; navigation was easy; response time was excellent, with no screen lag. Residents and attending loved the new format. Since then, the unknown conference has been presented monthly using WSI. In November 2016, we started presenting cases on WSI in the GYN tumor board. Some had no idea that this was even technically possible. All GYN weekly tumor boards are now presented using WSI. Conclusion Whole-slide imaging is a useful tool for teaching and presentation purposes. It can be easily implemented and integrated into our day-to-day pathology practice and resident training. The reluctance to use WSI is initially high among pathologists, but enthusiasm increases once implemented into regular practice. WSI provides for efficiencies and ease of collaboration in both educational and clinical case review settings such as institutional tumor boards.