Recently dual vertical transfer gates (VTGs), used in sub-micron pixels with full-depth deep-trench isolation (FDTI), have demonstrated superior performance in CMOS image sensors such as improvement of full well capacity (FWC) and charge transfer, as compared to a single VTG. In this work, we investigate characteristics of both pixel schemes based on two design examples, which is carried out using extensive 3D TCAD simulation and automated multi-objective optimization flow with various photodiode implantation conditions satisfying certain design specifications. Simulation results reveal that dual VTGs better control electrostatic potentials along the charge transfer path like a 3D fin-shaped transistor. The enhanced gate controllability also makes the VTG off potential insensitive to the nearby doping concentrations, which is not the case for the single VTG pixel, and thus provides more room for boosting FWC in the photodiode design according to the Pareto front analysis.