The purpose of the paper is to is to analyze the main factors that determine the parameters of bus comfort when transporting passengers by large-capacity buses. Ensuring the comfort of passenger transportation in a city bus is determined by compliance with ergonomic requirements, which, in turn, depends on the design features of the space intended for passengers. The paper examines these questions in relation to single-deck single and articulated public buses with a capacity of more than twenty-two passengers, standing or sitting, except for the driver. From the point of view of the Ukrainian legislation and regulatory framework, the concepts of the capacity of a passenger bus, its comfort, the main factors that determine the comfort of large-capacity buses are analyzed. The scope of use of buses of different classes and categories according to the types of connections and the length of the routes is determined taking into account the features of the design of the buses regarding the comfort and safety of the transportation of passengers and luggage and ensuring proper travel conditions. The ergonomic requirements for the comfort parameters of buses, the procedure for determining their comfort class and the scope of their use by types of connections and traffic modes are also considered. It was found that the factors that determine the comfort of large-capacity buses include the design and location of the seats, climate control (operating while the engine is running), heating (operating while the engine is running), windows (glass tinting, sun protection equipment (curtains or curtains), individual lighting, a microphone and loudspeaker, the presence of a luggage compartment, the presence of sanitary equipment (toilets with water or chemical cleaning, wash basins), the presence of such amenities as a refrigerator, cafe bar, TV in the cabin, as well as the type of suspension (classic (mechanical) or pneumatic/ pneumomechanical).