Affective polarization is a recent yet widespread phenomenon in democracies that significantly impacts various aspects of politics. In this paper, we argue that it can also shape citizens’ political beliefs through party cues. Using a panel survey experiment in Spain, we examine the extent to which partisan signals influence citizens’ attitudes toward a non-party- branded issue, specifically the ban on prostitution, and how affective polarization moderates this effect. Our results underscore the role of affective polarization in moderating the influence of partisan cues, particularly among highly polarized individuals. These findings highlight the capacity of affective polarization not only to deepen political divisions but also to expand the scope of partisan influence to non-politicized and neutral issues, offering new insights into its potential impact on attitude formation and decision-making.