Abstract In the dynamic era of advanced manufacturing technology, Laser Powder Bed Fusion (LPBF) have gained popularity in different domains due to its capability to build parts from bulk to miniature size with higher efficiency and precision. Ti-6Al-4V, a bio-inert metal alloy possesses a unique blend of profound mechanical and biocompatibility attributes, making it highly suitable for implant applications. This study reports the fabrication of Ti-6Al-4V alloy for implant application via LPBF process. The objective is to enhance the micro-mechanical and tribological properties of the fabricated Ti-6Al-4V component by identifying the optimal processing conditions. The fabricated component exhibited a maximum hardness of 395.26 HV and a minimum frictional coefficient of 0.3193 at 195 W laser power, 900 mm/s scanning speed, and 70 μm hatching distance. The wear rate and absorbed wear volume were measured as 1.265×10−5 mm3.N−1.min−1 and 0.3162 mm3 respectively under sliding conditions. At optimal processing state, the printed surface displayed an alpha-phase morphology with a homogeneous microstructural features due to uniform melting of powder particles that improved bond strength and minimized defects. This study offers an experimental insights into operational attributes, paving the way for accelerated production of Ti-6Al-4V alloy components using LPBF method and tailoring tribological properties to meet specific functional requirements.