A turbulent channel flow of a binary mixture of finite-size neutrally buoyant ellipsoidal particles is studied by using a parallel direct-forcing fictitious domain method at a friction Reynolds number of 180 and the particle aspect ratios of 1/3 (oblate particle) and 4 (prolate particle), respectively. The total particle volume fraction is fixed at 14.16% and 21.24% and the relative fraction of prolate and oblate particles are varied. The mean velocity profile normalized by the bulk velocity shows a strong difference between the single phase flow and particulate flow, while showing a small difference between mono-disperse and bi-disperse particulate flow cases. The lower fluid and particle Reynolds stress contributions in a high oblate particle volume fraction ratio cases lead to the drag reduction. Under moderate particle volume concentration, the oblate and prolate particle results show self-similarity of velocity profiles of solid phase, including particle velocity, concentration, orientation, and rotation. Both kinds of ellipsoidal particles tend to align their long axes with the streamwise direction in the whole channel.