Partial Sections Research Articles

Criteria for Determining Partial Common Use Sections in Condominium Buildings: Specification of the Objective Use Theory

Criteria for Determining Partial Common Use Sections in Condominium Buildings: Specification of the Objective Use Theory

Lutetian–Bartonian (Middle Eocene) micropalaeontology, biostratigraphy and palaeoecology of the Mengen Coal Basin, Northwest Türkiye (Turkey)

This study focuses on the upper Lutetian–lower Bartonian Tokmaklar Formation in the Mengen Basin of Northwest Türkiye (Turkey), examining various aspects such as biostratigraphy, palaeoecology, and isotope data (δ18O and δ13C), providing insights into the geological history and environmental conditions during this interval. Moreover, the study incorporates coal petrography on four samples to explore a potential correlation between the coalification process and the preservation of palynomorphs. The formation is informally divided into two distinct categories: a coal-bearing sequence positioned at the base of the formation and a coal-free sequence above it. However due to dense vegetation and soil cover in the area, the availability of suitable outcrops for measured sections and obtaining samples is severely limited. Therefore, we relied on drilling data from Turkish Coal Enterprises (TCE) for the purpose of coal exploration, as well as two partial sections (Ender and Çorak) from underground mining. Microapalaeontological evidences involving benthic foraminiferans, ostracods, and palynomorphs, along with isotope data (δ18O and δ13C), suggest that the Tokmaklar Formation was deposited as a result of a local transgressive process during the late Lutetian–early Bartonian. Furthermore, palynological data, particularly the existence of mangroves such as Nypa, lepidocaryoid palm and Acrostichum aureum, coupled with quantitative palaeoclimate analysis, the negative δ18O values, and the lower δ13C values indicate a warm, probably tropical climate under high rainfall.

Two-phase separation facilitating the ordering of L10-FePt: experimental and thermodynamic investigation on Fe–Pt–Cu phase diagrams

The L10-FePt nanocrystals exhibit unique magnetic and catalytic properties, but suffer from the ordering difficulty. The addition of Cu can facilitate the L10-FePt ordering for some Fe–Pt–Cu alloys, however, the action mechanism is far from being well understood. In this work, a systematic study has been performed to the phase diagrams of the Fe–Pt–Cu system. The isothermal sections at 600 °C, 750 °C and 1000 °C, as well as the partial vertical sections of Fe50Pt50–Cu50Pt50 and Fe50Pt50–Cu, were constructed. An emphasis has been paid to the L10-FePt phase, which has a wide composition range with a solid solubility of Cu up to 40.0 at% at 600 °C. Its order-disorder transition temperature decreases rapidly when deviating from 54 at% Pt, but at different lower rates along (FePt)100-xCux and (Fe50-xCux)Pt50 with the increase of Cu. The ternary miscibility gap which originates from the Fe–Cu side has been studied by both experimental determinations and thermodynamic calculations. The results indicate that, at certain low temperatures, for instance 300 °C, the metastable miscibility gap can expand even up to 45 at% Pt, entering the L10-FePt phase region. An ordering transition mechanism of the L10-FePt phase stimulating by a two-phase separation was thus proposed. For a specially designed disordered Fe–Pt–Cu alloy, a metastable two-phase separation can take place firstly in the annealing process, driving the Cu atoms forming Cu-rich particles, leaving a large number of vacancies in the alloy, and consequently, accelerate the atomic diffusion and stimulate the subsequent L10 ordering transition. These results will provide a new perspective for the composition design of Fe–Pt–Cu catalysts and magnetic recording media.

Digging into boring bryozoans: new characters and new species of Immergentiidae

Immergentia is an endolithic genus of ctenostome bryozoans and the sole member of the Immergentiidae. Etchings of their typical spindled-shaped and sometimes enantiomorphic borehole aperture in calcium carbonate substrates are accomplished by chemical dissolution. The tentacle crown of the bryozoan is essentially the only body part that extends beyond the shell surface when protruded. Previously, species were mainly described using external colony and zooidal characteristics or whole mounts, with partial histological sections conducted on a single species in 1947. Modern approaches, however, are hitherto missing. We examined the soft body morphology of Immergentia from different locations with confocal laser scanning microscopy and the production of 3D reconstructions. In addition, zooidal characteristics such as tentacle number, size, tubulets, and interzooidal distances were used to distinguish and describe species. The combination of conventional and modern methods revealed the presence of a cardiac constrictor and intercalary kenozooids that can interpose between the cystid appendages, something not previously reported in immergentiids, thus necessitating an amendment of the family diagnosis. The polypide typically has eight to ten tentacles, and the anus is positioned in the low or mid-lophophoral area. In addition, sequence data, including the mitogenome and the nuclear ribosomal genes (18S and 28S) of four species from five locations, are presented for the first time. Based on molecular and morphological data, a novel intertidal immergentiid from France, Immergentia stephanieae sp. nov., and a subtidal species from New Zealand, I. pohowskii sp. nov., are described. This work supplements the rather sparse existing knowledge on Immergentiidae and proposes additional characteristics to complement existing descriptions in order to enhance future species identification.

Studying the mining machine planetary-disc body loads when tunneling with stope back partial section

Studying the mining machine planetary-disc body loads when tunneling with stope back partial section

Palynology and palynofacies studies in the lowermost Jurassic of the Lusitanian Basin (Pereiros Formation of the Silves Group), Portugal: evidence of the first transgressive episode

The Silves Group of the Lusitanian Basin in Portugal represents the initial infill of the continental rifting basins that formed during the breakup of northern Pangaea regions. Evaporites, especially halite, mark the transition from continental to marine settings and the beginning of the deposition in passive margin basins. This work presents the results of the palynostratigraphic and palynofacies analysis of two partial sections from the Pereiros Formation at the top of the Silves Group. The two sections are composed of sandstones, mudstones and dolostones interpreted as deposited in fluvial and lacustrine settings without apparent marine influence. The palynological content is diverse and wellpreserved, dating both sections to the early Hettangian (Lower Jurassic), indicated by the presence of spores Ischyosporites variegatus, Kraeuselisporites reissingeri, Porcellispora longdonensis and the pollen grains Perinopollenites elatoides and Pinuspollenites minimus. The palynological content of one of the sections (Lamas I) is noticeable by microforaminifera linings, suggesting evidence for a hitherto marine incursion at this age in the Silves Group stratigraphy. The beds that yielded the microforaminifera linings are interpreted as having been deposited in an estuarine-type setting, created by the first and short-lived marine transgressive event in the Lusitanian Basin during the early Hettangian.

Rescue of a Cilevirus from infectious cDNA clones

Reverse genetics systems represent an important tool for studying the molecular and functional processes of viral infection. Citrus leprosis virus C (CiLV-C) (genus Cilevirus, family Kitaviridae) is the main pathogen responsible for the citrus leprosis (CL) disease in Latin America, one of the most economically important diseases of the citrus industry. Molecular studies of this pathosystem are limited due to the lack of infectious clones. Here, we report the construction and validation of a CiLV-C infectious cDNA clone based on an agroinfection system. The two viral RNA segments (RNA1 and RNA2) were assembled into two binary vectors (pJL89 and pLXAS). Agroinfiltrated Nicotiana benthamiana plants showed a response similar to that observed in the natural infection process with the formation of localized lesions restricted to the inoculated leaves. The virus recovered from the plant tissue infected with the infectious clones can be mechanically transmitted between N. benthamiana plants. Detection of CiLV-C subgenomic RNAs (sgRNAs) from agroinfiltrated and mechanically inoculated leaves further confirmed the infectivity of the clones. Finally, partial particle-purification preparations or sections of CiLV-C-infected tissue followed by transmission electron microscopy (TEM) analysis showed the formation of CiLV-C virions rescued by the infectious clone. The CiLV-C reverse genetic system now provides a powerful molecular tool to unravel the peculiarities of the CL pathosystem.

Ti-Al-based alloys with Mo: high-temperature phase equilibria and microstructures in the ternary system

ABSTRACT Molybdenum is one of the major alloying elements in TiAl-based alloys for high-temperature structural applications developed over the last decades. This is due to its stabilising effect on the (βTi) phase at high-temperatures, which crucially improves the hot-workability of such alloys. For further alloy development, an exact knowledge of the phase equilibria in the Ti–Al–Mo system is essential. However, there are still uncertainties and inconsistencies related to the ternary phase diagram. In this study, a series of ternary alloys was produced and heat-treated between 700 and 1300 °C. Composition, structure, and thermal stability of the phases were analysed and the resulting phase equilibria were established by applying a combination of scanning electron microscopy (SEM), electron probe microanalysis (EPMA), differential scanning calorimetry (DSC), and high-energy X-ray diffraction (HEXRD). From these results, a series of partial isothermal sections is obtained illustrating the phase equilibria in the Ti-rich part of the Ti–Al–Mo system.

Penetrating Cervical Injury Due to Throat Slitting in Children: 1 Case Reported at Mopti Hospital (Mali)

The impact of the media and security crises (rebellions, acts of terrorism, intercommunity conflicts) on children often results in the practical reproduction of what they see and hear. Anterior penetrating injuries to the neck pose a life-threatening situation and the causes vary among countries around the world. They include stab wounds, gunshot wounds, vehicle accident injuries, and neck lacerations. They pose a great challenge to treating surgeons because of the important structures in the neck that can be affected. We report a case of knife slitting of a child by one of his classmates during a simulation game in a conflict zone in central Mali. A 5-year-old boy was cut in the throat by a 9-year-old friend with a knife. According to the patient's father who testified, the cut was committed in the play area where the oldest friend placed the patient in a supine position and then cut him in the throat with a knife; as if to imitate adults. On exploration, the lesion assessment found an anterior cervical wound which was horizontal with linear borders located between the sternocleidomastoid muscles without damage to them and the large vessels. A partial section of the esophagus and trachea was noted. There was no neurological or cervical spine involvement on X-ray. Laryngo -tracheal repair with two control tractor wires and then orotracheal re-intubation; Finally a suture of the sternothyroid muscles and skin closure. The postoperative course was simple. Penetrating trauma is rare in children, their management is a challenge. They are serious and put the patient's vital prognosis at stake.

Damage identification for jacket offshore platforms using Transformer neural networks and random decrement technique

A deep learning method is proposed to identify damages in jacket offshore platforms, which integrates the random decrement technique (RDT) and Transformer neural network. RDT is utilized to process the noisy strain response signals from various measurement points on the platform under random excitation, and the Transformer network is used to localize the damages and assess their severities. Numerical simulations and experimental studies are used to demonstrate that the proposed method is effective. The numerical model applied in this study is a jacket platform, including single and multiple damage cases in the entire section and partial section (two-fifths of the entire section) with minor severities (<5%), and different noise levels are considered. Additionally, the effect of measurement positions on identification accuracy of minor and major damage is discussed. Furthermore, the proposed method is validated by experimental studies using a jacket platform model fixed on a shaking table, where different severities of single and multiple damages are considered. Results of the numerical and experimental studies demonstrate that the proposed RDT-Transformer approach can accurately determine the location of structural damage and identify its severity.

Diagnostic value of 3D Optical Coherence Tomography Multimode Images in the Diagnosis of Acute Central Serous Chorioretinopathy.

Spectral-Domain Optical Coherence Tomography (SD-OCT) provides non-invasive, high-speed, high-resolution, three-dimensional cross-section imaging of the macula. This study aimed to investigate the diagnostic value of the multimodal imaging technique of three-dimension (3D) optical coherence tomography (OCT) (3D-OCT) for the diagnosis and characterization of acute central serous chorioretinopathy (CSC). In this prospective clinical study 3D-OCT examinations of 82 cases with acute CSC were performed on the macular area, and the image characteristics were analyzed. Our study included a total of 87 eyes from 82 cases of CSC patients, 67 males and 15 females (mean age ± standard deviation (SD): 42.89 ±7.80 years old; age range: 27 to 56 years old. The 3D-OCT images were evaluated for the presence of subretinal fluid, subretinal space, fluctuation of the internal limiting membrane (ILM), folds of retinal pigment epithelial (RPE), retinal pigment epithelium detachment (PED), and flat irregular PED. The foveal thickness was measured using the manual caliper of OCT software. The OCT B-scan images showed 87 (100%) eyes had exudative retinal detachment (ERD), 38 (44%) had flat irregular PED, 36 (41%) had PED, 8 (9%) had subretinal turbidity structure, 2 (2%) had subretinal dot-like precipitates, 1 (1%) had focal choroidal excavation (FCE), and 1 (1%) eye had fluctuation of internal limiting membrane (FI). In the ILM-RPE thickness map, all eyes had a round or round like regular uniform domes. Fifty-seven (66%) domes were limited in the examination area and 30 (44%) domes were beyond the scope of this examination and only a partial section of the dome could be observed. In the en-face image, all eyes had a round or round-like black figure that corresponded with domes in the ILM-RPE thickness map. In RPE surface, 76 (87%) eyes had a shallow plate depression, 71(82%) had small focal uplift, and 1 (1%) eye had a focal concave feature. In the OCT ILM-RPE thickness, en-face image, and RPE surface maps, acute CSC exhibited specific imaging characteristics that can be helpful for reliable diagnosis and differential diagnosis of CSC.

Phase equilibria at 500 °C of the Mg-Nd-Zn system in the region of 0–50 at%Nd

The phase equilibria at 500 °C of the Mg–Nd–Zn system in the region of 0–50 at.% Nd were investigated by combining the electron probe microanalysis (EPMA) and X-ray diffraction (XRD) of the equilibrated alloys. The partial isothermal section was constructed. Eight ternary phases (τ1 to τ6, τ8 and T-NdMg12) were found at 500 °C. Among them, τ8 is the newly found ternary compound. T-NdMg12 is the Zn-stabilized Mnl2Th-type NdMg12 phase. Its composition range was measured to be Nd7.6-7.7Mg84.5-88.7 Zn3.7-7.8. The homogeneity ranges of the seven ternary compounds (τ1 to τ6 and τ8) were well determined. The solubilities of the third elements in the binary compounds of the three binary systems were also well measured. The lattice parameters of the τ1, τ2 and τ5 phases were determined to be a = 0.9709 (3) nm/b = 1.1253 (4) nm/c = 0.9545 (3) nm at Nd7.8Mg57.0 Zn35.2 (τ1), a = 1.46234 (1) nm/c = 0.8706 (1) nm at Nd7.1Mg28.5Zn64.4 (τ2) and a = 2.0883 (2) nm at Nd16.7Mg18.5Zn64.8 (τ5), respectively.

Compression behavior of GFRP reinforced hybrid fibre reinforced concrete short columns subjected to eccentric loading

This paper presents the results of an experimental study carried out on the GFRP reinforced hybrid fibre concrete short columns subjected to eccentric compression. In this study, hybrid fiber-reinforced concrete was prepared in different volume ratios of hybrid fibers and the cooperative effect of the GFRP reinforcement and the steel-PVA hybrid fibre concrete with different fibre ratios under eccentric loading was explored. 10 GFRP reinforced hybrid fibre concrete short columns and 2 plain reinforced concrete short columns were tested to investigated their eccentric compressive properties. The tests results are presented in terms of failure modes, longitudinal reinforcement strain, concrete compressive strain and compressive load capacity of GFRP reinforced hybrid fibre concrete eccentrically compressed short columns. The results show that the concrete on the compressed side was crushed when the specimen under both the initial eccentricity of 50 mm and 100 mm the reinforcement were pulled on the tension side of specimen under a larger initial eccentricity of 100 mm. The addition of fibres can effectively prevent the crack generation and development and improve the bonding property between reinforcement and concrete. Besides, the addition of steel fibre contributes a better performance on the ultimate compressive capacity of specimen under a lager initial eccentricity with an optimal ratio of steel fibre at 1.4 %. PVA fibre effectively improve the ductility of the concrete, so that the hybrid fibre concrete elements remain relatively its integrity after failure. Finally, considering the effect of GFRP reinforcement and different ratios of steel fibre and PVA fibre on the compressive capacity of short concrete columns, the equation for the calculation of the ultimate compressive capacity of partial sections of eccentric columns is proposed, and a good agreement was observed between the tested and calculated value.

Insights into DNA Damage in Regenerating Young and Aged Mouse Livers

Abstract Background The maintenance of genome stability is a key process to slow aging. One of the mechanisms ensuring this stability is the correct coordination of origins of replication (ORI), resulting in the successful transmission of DNA. Previously, we mapped and compared ORI firing between young and aged mice in vivo, using a regenerating liver mouse model. We confirmed a decreased hepatocyte ORI efficiency in aged mice, known to have impaired liver regeneration. ORI firing proved to be fully rescued when blocking the aged mice's ATR serine/threonine-protein kinase, suggesting that the DNA replication checkpoint actively mediates ORI firing impairment upon DNA damage detection. Aims To explore DNA damage differences between young and aged mice regenerating livers. Methods To induce proliferation, mice were subjected to partial hepatectomy (PH) and liver sections were harvested at different timepoints. Immunohistochemistry staining (IHC) were used to address proliferation and DNA damage, using Ki67 and serine 139 phosphorylated histone H2AX (g-H2AX) as markers, respectively. Results We confirmed a lack of Ki67 signal in young and aged mice prior to PH. The signal takes off at 24-28h post-PH and reaches its peak at 36-48h, which is significantly lower in aged mice. After 48h post-PH, young hepatocytes’ Ki67 reaches its basal level 120h post-PH. However, aged hepatocytes’ Ki67 is maintained at low levels overtime. Next, we compared DNA damage kinetics between young and aged mice livers. Both mouse groups present an increase of g-H2AX upon PH, higher in young mice. The g-H2AX signal decreases in young hepatocytes after 48h post-PH until disappearing 120h post PH. Aged mice hepatocytes maintain the g-H2AX rates overtime after 48h post-PH. Conclusions Our data suggests that hepatocytes develop DNA damage upon proliferation, which is able to be resolved in young mice hepatocytes but remains present in aged livers, ultimately leading to impaired liver regeneration.

Phase equilibria in the Ti-Al-W system between 800 and 1300 °C

Within the search for new improved high-temperature materials for gas turbine applications with higher energy saving potential and improved greenhouse gas balance, new Ti-Al-W based alloys have recently been discussed. A basic prerequisite for targeted alloy development is the precise knowledge of the phases and phase relationships that determine the microstructure and mechanical behavior of the material. However, there is not much known about the phase equilibria in the application- and manufacturing-relevant temperature range between 800 and 1300 °C. No information on ternary intermetallic compounds or possible ordering of the cubic (βTi,W) solid solution is reported in the literature. In the present investigation, the Ti-rich part of the Ti–Al–W system between 800 and 1300 °C was studied. Ten different alloys were heat-treated and quenched samples were characterized by scanning electron microscopy (SEM), electron probe microanalysis (EPMA), high-energy XRD (HEXRD), differential thermal analysis (DTA), and transmission electron microscopy (TEM). Based on these results, a series of partial isothermal sections was established. The investigations show that there is no ternary intermetallic compound in this system and the (W) solid solution forms equilibria with the binary Ti-Al phases.

КРИСТАЛЛИЗАЦИЯ СТЕКОЛ В РАЗРЕЗЕ Nа2O·2B2O3 — BaO·2B2O3 НАТРИЕВО-БАРИЕВО-БОРАТНОЙ СИСТЕМЫ

The results of crystallization of glass powders of the diborate section of the Na2O BaO B2O3 system are presented. The glass transition temperatures and temperature regions of crystallization at a heating rate of 10 K/min were determined by DTA and XRD methods; the formed crystalline phases were identified, and the nature and temperatures of their melting were established. It is shown that the section under study is not a pseudobinary system, but only a partial section of the sodium-barium borate system. It is shown that the Na2O·2BaO·9B2O3 compound is the phase of primary crystallization in the section; its field covers the majority of the section. The second known ternary compound, Na2O·2BaO·5B2O3, apparently melts peritectically. It has been established that during long-term heat treatment of glasses in a monolithic state, a new phase is formed in them with an approximate composition of Na2O·2BaO·6B2O3.

Formation and structure of 1/1 cubic approximants in the Cd-Mg-Ce system: The identification of a new structural variant

The stability region of the 1/1 cubic crystalline approximant to icosahedral quasicrystal in the Cd-Mg-Ce system was investigated in detail. The partial isothermal section of the ternary phase diagram at 673 K was determined in the range from 0 to 18 at% Ce, where it was shown that the approximant spans a wide compositional range of Cd57−86Mg0−29Ce14–15. Mg addition was found to shift the stability region to lower temperatures. Besides, the approximant was found to be in equilibrium not with the Cd-Mg solid solution but with (Cd,Mg)17Ce2 and (Cd,Mg)11Ce compounds as opposed to the previous work [J. Alloys Compd. 822 (2020) 153541]. Based on the diffraction data (both X-ray and electron), to our surprise, a new variant of 1/1 cubic approximant was identified within the compositional range. The prototype Cd37Ce6 structure (space group Pn3̅) which dominates near the Cd-rich end was found to be partly taken over by the Cd25Eu4-type structure (space group Fd3̅) with a doubled unit cell in the higher-Mg part of the compositional range. The atomic structure with both Pn3̅ and Fd3̅ symmetries were determined by means of single-crystal X-ray diffraction measurement. Their refined atomic structures were compared and the preferential sites for Mg substitution are revealed.

Quorum sensing inhibition through site-directed mutation by deletion PCR

Quorum sensing induces biofilms and virulence factors that are adverse industrially and medically. Nowadays, quorum sensing inhibitions focus on signal analogs or signal degradation, but these methods have several downsides, which are temporal and affected by several environmental factors. In this research, we used deletion PCR to perform site-directed mutagenesis on the quorum sensing pathway gene and then analyzed its effects on quorum sensing. Serratia fonticola DSM 4576 strain was utilized as the research strain, and the gram-negative bacteria's universal quorum sensing pathway, which is conducted by acyl-homoserine lactone (AHL), was analyzed. The structure and active site of the AHL synthase enzyme encoded by S. fonticola DSM 4576's luxI-type gene were predicted. The gene's partial section solely encodes the enzyme's active site. By using sequence and ligation-independent cloning, the obtained mutagenic gene was cloned into the suicide vector pEX18Ap. The recombinant vector was used to transform wild-type S. fonticola DSM 4576 strains, and the mutants were determined through two-step selections and PCR genotyping. The gene expression level and biofilm formation were quantitatively analyzed through RT-PCR and biofilm assay, and no significant difference was noted in the gene expression between wild types and mutants. However, when mutants were compared to wildtypes, there was a significant decrease in biofilm formation as a result of quorum sensing induced bioreaction. Thus, we propose a quorum sensing inhibitory technique based on enzyme mutation on the quorum sensing pathway, and we proved the feasibility of enzyme active site's site-directed mutation through deletion PCR.

Phase Equilibria of the In–Pd–Sn System at 500 °C and 800 °C: Experimental Study and CALPHAD Modeling

Phase equilibria in the In-Pd-Sn system were investigated by a combination of key experiments and thermodynamic modeling. Partial isothermal sections at 500 °C and 800 °C of the In-Pd-Sn system for Pd contents above 66 at.% have been plotted experimentally using scanning electron microscopy with energy-dispersive X-ray spectroscopy (SEM/EDX) and X-ray diffraction (XRD). The solubility of the third component in binary compounds InPd3 and Pd3Sn was determined. The new ternary compound τ1 was found in Pd contents ranging from 20 to 25 at.% and at Sn contents varying from 5 to approximately 17 at.% Sn. This compound crystallizes in an Al3Ti-type tetragonal structure. Isostructural InPd2 and Pd2Sn phases from the In-Pd and Pd-Sn binary compositions form a continuous phase field in the ternary system at both temperatures. The temperatures of the solidus, liquidus, and phase transitions of the alloys along the Pd-In50Sn50 line were measured using DTA/DSC. Thermodynamic calculation of the In-Pd-Sn ternary system is performed using the CALPHAD method using the Thermo-Calc® software. The thermodynamic properties of the disordered fcc and liquid phases were described by the Redlich-Kister-Muggianu model. To describe intermetallic phases, namely, InPd3, Pd3Sn, τ1 and Pd2(InxSn1-x), a two-sublattice models was used. Thermodynamic description of the In-Pd-Sn system obtained in this study is in good agreement both with our results and the published experimental data.

A GNSS/LiDAR/IMU Pose Estimation System Based on Collaborative Fusion of Factor Map and Filtering

One of the core issues of mobile measurement is the pose estimation of the carrier. The classic Global Navigation Satellite System/Inertial Measurement Unit (GNSS/IMU) integrated navigation scheme has high positioning accuracy but is vulnerable to Global Navigation Satellite System (GNSS) signal occlusion and multipath effect. Simultaneous Localization and Mapping (SLAM) is not affected by signal occlusion, but there are problems such as error accumulation and scene degradation. The multi-sensor fusion scheme combining the two technologies can effectively expand the scene coverage and improve the positioning accuracy and system robustness. However, the current scheme has some limitations. On the one hand, GNSS plays a less important role in most SLAM systems, only for initialization or as a closed-loop factor and other auxiliary work. On the other hand, in the fusion method, most of the current systems only use filtering or graph optimization, without taking into account the advantages of both. Aiming at pose estimation for mobile carriers, this paper combines the advantages of the global optimization of the factor graph and the local optimization of filtering and proposes a GNSS-IMU-LiDAR Constraint Kalman Filter (abbreviated as GIL-CKF), which has the characteristics of full coverage and effectively improving absolute accuracy and high output frequency. The scheme proposed in this paper consists of three parts. Firstly, an extensible factor map is used to fuse the positioning information from different sources, including GNSS, IMU, LiDAR, and a closed-loop map, to maintain a high-precision SLAM system, and the output is used as Multi-Sensor-Fusion-Odometry (MSFO). Then, the scene is divided according to the GNSS quality factor, and a Scene Optimizer (SO) is designed to filter GNSS pose and MSFO. Finally, the results are input into the Extended Kalman Filter (EKF) together with the original IMU data for further optimization and smoothing. The experimental results show that the integration of high-precision GNSS positioning information with IMU, LiDAR, a closed-loop map, and other information through the factor map can effectively suppress error accumulation and improve the overall accuracy of the SLAM system. The SO based on GNSS indicators can fully retain high-precision GNSS positioning information, effectively play their respective advantages of filtering and graph optimization, and alleviate the conflict between global and local optimization. SO with EKF filtering furthers optimization, can improve the output frequency, and smooth the trajectory. GIL-CKF can effectively improve the accuracy and robustness of pose estimation and has obvious advantages in multi-sensor scene complementarity, partial road section accuracy improvement, and high input frequency.