You have accessJournal of UrologyUrodynamics/Lower Urinary Tract Dysfunction/Female Pelvic Medicine: Female Incontinence: Therapy I1 Apr 2018PD05-05 TRANSOBTURATOR TAPE: OVER 10 YEARS FOLLOW-UP Franca Natale, Ester Illiano, Chiara La Penna, Alessandro Zucchi, Francesca Parisi, Lorenzo Alunni, and Elisabetta Costantini Franca NataleFranca Natale More articles by this author , Ester IllianoEster Illiano More articles by this author , Chiara La PennaChiara La Penna More articles by this author , Alessandro ZucchiAlessandro Zucchi More articles by this author , Francesca ParisiFrancesca Parisi More articles by this author , Lorenzo AlunniLorenzo Alunni More articles by this author , and Elisabetta CostantiniElisabetta Costantini More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2018.02.413AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES The growth of the elderly population in western countries highlights the importance of studying the long-term outcomes of the various treatments of chronic conditions, including urinary incontinence. The aim of this study is to assess the outcomes in incontinent patients who underwent TOT with a 10-year minimum follow-up. METHODS This is a single-center prospective study on women who underwent TOT for stress urinary incontinence (SUI) or stress predominant mixed urinary incontinence. The pre-operative evaluation included: history; urogynaecological examination; cough stress test; urodymamics; UDI-6 and IIQ questionnaires for symptoms; the King′s Health Questionnaire (KHQ) for QoL. In Sept.-Oct. 2017 all patients who had undergone TOT before 2007 were recalled for follow-up. They completed the same pre-op questionnaires and the Patient Global Impression of Improvement (PGI-I): success was defined as ′very much better′ or ′much better′ on the PGI-I scale. The primary outcome was the SUI cure rate. Secondary outcomes included improvement in QoL, effect on urinary symptoms and late adverse events. Institutional Review Board Committees approved this study; participants gave informed consent. Statistical analysis: McNemar chi-square test; Fisher′s exact test. RESULTS From January 2003 to December 2007, 136 consecutive patients underwent TOT. Thirteen patients were lost to follow-up, so we report data on 123 patients. Mean age was 58.3±9.94; median parity was 2; mean BMI 27.22±2.76; 87 patients (70.2%) were menopausal. At a mean follow-up of 145 months, 77 patients (62.6%) were subjectively cured for SUI. Of the 46 failed patients only 10 underwent further SUI surgery: 8 underwent TVT and 2 underwent bulking agent therapy. Urgency reduced statistically significantly (from 67.5% to 38.3%), as did urgency urinary incontinence (from 56.9% to 31.7%). De novo urgency occurred in 7.3% of cases. Voiding symptoms increased from 8.9% to 18.7%. De novo voiding symptoms appeared in 14.6% of patients. All domains of the KHQ except general health and sleep saw statistically significant improvements. We had 5 cases of partial mesh extrusion, requiring tape revision; none became incontinent. CONCLUSIONS Our study demonstrates that in the period of ten or more years after TOT surgery, cure rates are lower than in shorter-term studies, however, at 62.6%, they may still be considered satisfactory. It is difficult to ascertain if a patient′s dissatisfaction 10 years or more after surgery is due to long-term treatment failure or to general factors like age or another pathology. © 2018FiguresReferencesRelatedDetails Volume 199Issue 4SApril 2018Page: e146 Advertisement Copyright & Permissions© 2018MetricsAuthor Information Franca Natale More articles by this author Ester Illiano More articles by this author Chiara La Penna More articles by this author Alessandro Zucchi More articles by this author Francesca Parisi More articles by this author Lorenzo Alunni More articles by this author Elisabetta Costantini More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...