Parotid Gland Tumors Research Articles

Preoperative Multiparametric Ultrasound and Fine Needle Aspiration Cytology evaluation of parotid gland tumors: which is the best technique?

To evaluate the pre-surgical diagnostic value of Multiparametric Ultrasound (MPUS) and Fine Needle Aspiration Cytology (FNAC) in differentiating parotid gland tumors, comparing the results with histology. The study enrolled 84 patients with parotid gland lesions surgically treated in a single tertiary center and evaluated by MPUS. Each patient underwent FNAC. Histological examination was considered the gold standard. Histology identified 62 benign tumors and 22 malignancies. In the differential diagnosis between malignant and benign lesions, B-mode Ultrasound (US), Color-Doppler US, Contrast-Enhanced US (CEUS), Elastography (USE) and FNAC showed the following values of sensitivity: 82%, 81%, 86%, 77%, 73% respectively; specificity: 97%, 61%, 95%, 71%, 97% respectively; PPV: 90%, 43%, 86%, 50%, 89% respectively; NPV: 93%, 90%, 95%, 88%, 91% respectively; and accuracy: 89%, 71%, 90%, 78%, 84% re-spectively. CEUS proved to be a valid and accurate method for identifying malignant tumors of parotid gland; the combination of B-mode US with CEUS showed similar diagnostic accuracy, but better sensitivity than CEUS taken alone. USE did not improve the diagnostic performance of the B-mode US, alone or in association with CEUS; however, it revealed the highest diagnostic accuracy in the differentiation between benign lesions. FNAC demonstrated lower values in comparison with CEUS and with USE. Therefore, according to our study, MPUS could be proposed as a valid alternative to FNAC.

DIAGNOSTIC ACCURACY OF COLOR ANDPULSED DOPPLER IN THE EVALUATION OF PAROTID GLAND TUMORS

Background: The parotid glands are the largest salivary glands in humans and are frequently involved in various primary & systemic disease processes. The most common benign parotid gland tumor is pleomorphic adenoma. Around 20% of parotid tumors are malignant with most common parotid tumors being mucoepidermoid carcinoma and adenoid cystic carcinoma.
 Objective:
 To determine the diagnostic accuracy of pulsed and color Doppler for the evaluation of parotid gland cancer. 
 Methods:
 It was a cross sectional study by design carried out in Department of Radiology and Department of Maxillofacial Surgery, Mayo Hospital – Lahore in a duration of three year. All the patients were examined with mind-ray 7.5 MHz linear transducer.
 There are three methods used collectively; Grey Scale, color Doppler and Pulsed Doppler in sonographic examination. Color Doppler and pulsed Doppler demonstrate number of blood vessels within the tumor, their Peak Systolic Velocity and Resistive Index respectively.
 Histo-pathological results were correlated post operatively with the data obtained from Doppler ultrasound. Data was analyzed using SPSS 23.0 
 Results:
 In this study, 192 patients were included .The mean age was 39.42 ± 11.93 years. 58.85% (112) were male patients and 41.15 %( 80) patients were females. The solid masses with regular margins were evaluated and the diagnostic accuracy of pulsed Doppler was found to be 87.5% taking histopathology as gold standard. 
 Conclusion:
 This study shows pulsed Doppler to be more accurate tool for diagnosis of parotid gland tumor as compared to color Doppler taking histopathology as gold standard.

Quantitative assessment of the parotid gland using computed tomography texture analysis to detect parotid sialadenitis

We aimed to quantitatively assess the parotid gland by using computed tomography (CT) texture analysis to detect parotid sialadenitis (PS). This retrospective case-control study included 43 patients with PS who underwent CT and magnetic resonance imaging (MRI). Parotid glands with an abnormal signal (STIR: High) on MRI were identified as showing PS. Patients with parotid gland tumors, bilateral PS, marked fatty degeneration, and severe artifacts on CT were excluded. The texture features of parotid glands with PS and the contralateral normal parotid glands were analyzed using the open-access software LIFEx. The regions of interest were manually placed by tracing contours of both parotid glands on CT images. The results were tested with the paired t-test (or Wilcoxon rank-sum test when appropriate). Receiver operating characteristic (ROC) curve analysis was performed to assess the ability of texture features to predict PS. Six gray level run length matrix features, 2 neighborhood gray level difference matrix features, and 5 gray level zone length matrix features displayed significant differences between PS and normal glands (P ≤ .047). ROC curve analysis showed acceptable accuracy in 4 texture features. CT texture analysis allowed quantitative assessment of parotid glands and may have the potential to detect PS.

Improving diagnosing performance for malignant parotid gland tumors using machine learning with multifeatures based on diffusion-weighted magnetic resonance imaging.

In this study, the performance of machine learning in classifying parotid gland tumors based on diffusion-related features obtained from the parotid gland tumor, the peritumor parotid gland, and the contralateral parotid gland was evaluated. Seventy-eight patients participated in this study and underwent magnetic resonance diffusion-weighted imaging. Three regions of interest, including the parotid gland tumor, the peritumor parotid gland, and the contralateral parotid gland, were manually contoured for 92 tumors, including 20 malignant tumors (MTs), 42 Warthin tumors (WTs), and 30 pleomorphic adenomas (PMAs). We recorded multiple apparent diffusion coefficient (ADC) features and applied a machine-learning method with the features to classify the three types of tumors. With only mean ADC of tumors, the area under the curve of the classification model was 0.63, 0.85, and 0.87 for MTs, WTs, and PMAs, respectively. The performance metrics were improved to 0.81, 0.89, and 0.92, respectively, with multiple features. Apart from the ADC features of parotid gland tumor, the features of the peritumor and contralateral parotid glands proved advantageous for tumor classification. Combining machine learning and multiple features provides excellent discrimination of tumor types and can be a practical tool in the clinical diagnosis of parotid gland tumors.

Role of Fine Needle Aspiration Cytology (FNAC) in Preoperative Diagnosis of Parotid and Submandibular Gland Neoplasm

Background: The overall incidence of salivary gland neoplasm is 2.5-3.0 per 100000 per year. Salivary gland malignancies account for about 5% of head-neck malignancies. Though, it is uncommon but not rare in our country. Fine Needle Aspiration Cytology (FNAC) has been widely used for many years as a method for assessing salivary gland lesion preoperatively. It is a simple, quick, inexpensive and minimally invasive technique used to diagnose different types of salivary gland neoplasm. Objectives: To see the frequency of malignancy in parotid and submandibular salivary gland neoplasm and also to find out the role of FNAC in their preoperative diagnosis. Histopathological examination of the resected parotid and submandibular gland neoplasm was considered as gold standard to compare FNAC report of this study. Methods: This was a cross – sectional study which was conducted in the Department of Otolaryngology – Head & Neck Surgery, Dhaka Medical College Hospital, Dhaka from January 2017 to June 2018. Purposive sampling method was used to collect data. Pre-tested structured data sheet was used to record information. After collection, data were edited by meticulous checking and re-checking. Data were analyzed using SPSS for windows version 22. Results: After histopathological confirmation of the resected specimen, most common benign parotid tumour was pleomorphic adenoma 76.7% followed by warthin’s tumour 16.7%. In benign submandibular gland neoplasm, pleomorphic adenoma was the commones 87.5% followed by haemangioma 12.5%. Commonest malignant tumour of submandibular gland was adenoid cystic carcinoma 50.0%. In our study sensitivity of FNAC was 75.0%, specificity 94.74% and overall accuracy was 90%. Positive predictive value and negative value were 81.82% and 92.31% respectively. Conclusion: It can be concluded that fine needle aspiration cytology is a safe, cheap and useful preoperative diagnostic tool in the diagnosis of malignancy in parotid and submandibular gland, but as fine needle aspiration cytology partly depends on operator skill, it may give false negative and false positive result. Bangladesh J Otorhinolaryngol 2021; 27(2): 124-129

An update on extracapsular dissection for the management of parotid gland pleomorphic adenoma.

Superficial parotidectomy has been the gold standard for surgical removal of benign mobile parotid gland tumours. The comparatively newer technique of extracapsular dissection, which involves careful dissection of the tumour itself without the need for formal gland excision, has gained popularity in recent years. Tumours can be removed via smaller incision, and the technique reduces the risk of Frey's syndrome (gustatory sweating) and hollowing at the site of surgery. The risk of facial nerve damage can also be lower with extracapsular dissection. If done carefully, the incidence of tumour recurrence, particularly for pleomorphic adenomas, is comparable with formal parotidectomy. We provide a brief update overview of the current evidence for extracapsular dissection in the treatment of benign parotid tumours and include several meta-analyses which provide evidence for the safety of the technique. We have also included our audited results of over 100 recent extracapsular dissections, with 0% incidence of permanent facial nerve weakness, reported Frey's syndrome and recurrence rates over the last 5years.

Total Superficial Parotidectomy: Pros and Cons

Background: Total superficial parotidectomy is the most commonly used approach in excising the tumors that affect the superficial lobe of the parotid gland, whether they're benign or malignant. The aim of the study is to evaluate the benefits and drawbacks of total superficial parotidectomy for parotid gland tumors within five years of follow-up. Patients and methods: Nineteen patients with lateral facial swelling affecting the parotid region were included in this study. All of them operated under general anesthesia with oral endotracheal intubation, where Modified Blair Incision (lazy S incision) was utilized in all cases. Anterograde dissection with facial nerve identification was accomplished with total superficial parotidectomy. Results: Fifteen patients had benign parotid tumors, and only four patients had well-differentiated mucoepidermoid carcinoma. Skin necrosis of the distal tip of the postauricular flap was the most commonly observed postoperative complication, it occurred in five patients; facial nerve weakness was observed in the another three patients. Conclusions: total superficial parotidectomy is an efficient, safe technique for benign and malignant tumors affecting the superficial lobe of the parotid gland with minimum postoperative complications.

Diffusion kurtosis imaging and dynamic contrast-enhanced MRI for the differentiation of parotid gland tumors

ObjectiveTo assess the usefulness of combined diffusion kurtosis imaging (DKI) and dynamic contrast-enhanced MRI (DCE-MRI) in the differentiation of parotid gland tumors.MethodsSeventy patients with 80 parotid gland tumors who underwent DKI and DCE-MRI were retrospectively enrolled and divided into four groups: pleomorphic adenomas (PAs), Warthin tumors (WTs), other benign tumors (OBTs), and malignant tumors (MTs). DCE-MRI and DKI quantitative parameters were measured. The Kruskal–Wallis H test and post hoc test with Bonferroni correction and ROC curve were used for statistical analysis.ResultsWTs demonstrated the highest Kep value (median 1.89, interquartile range [1.46–2.31] min−1) but lowest Ve value (0.20, [0.15–0.25]) compared with PAs (Kep, 0.34 [0.21–0.55] min−1; Ve, 0.36 [0.24–0.43]), OBTs (Kep, 1.22 [0.27–1.67] min−1; Ve, 0.28 [0.25–0.41]), and MTs (Kep, 0.71 [0.50–1.23] min−1; Ve, 0.35 [0.26–0.45]) (all p < .05). MTs had the lower D value (1.10, [0.88–1.29] × 10−3 mm2/s) compared with PAs (1.81, [1.60–2.20] × 10−3 mm2/s) and OBTs (1.57, [1.32–1.89] × 10−3 mm2/s) (both p < .05). PAs had the lower Ktrans value (0.12, [0.07–0.18] min−1) compared with OBTs (0.28, [0.11–0.50] min−1) (p < .05). The cutoff values of combined Kep and Ve, D, and Ktrans to distinguish WTs, MTs, and PAs sequentially were 1.06 min−1, 0.28, 1.46 × 10−3 mm2/s, and 0.21 min−1, respectively (accuracy, 89% [71/80], 91% [73/80], 78% [62/80], respectively).ConclusionThe combined use of DKI and DCE-MRI may help differentiate parotid gland tumors.Key Points• The combined use of DKI and DCE-MRI could facilitate the understanding of the pathophysiological characteristics of parotid gland tumors.• A stepwise diagnostic diagram based on the combined use of DCE-MRI parameters and the diffusion coefficient is helpful for accurate preoperative diagnosis in parotid gland tumors and may further facilitate the clinical management of patients.

An overview of cases of parotid gland tumors managed in a teaching hospital, North-west, Nigeria

&#x0D; &#x0D; &#x0D; &#x0D; Objective: Salivary gland tumors are mostly slow growing and painless. Majorities are located in the parotid glands and are benign. Treatment of these parotid tumors may endanger the facial nerve. This study evaluated the clinical presentation and management of parotid gland tumors in Kaduna, North-west, Nigeria.&#x0D; Methods: This was a retrospective study of patients that were treated for parotid gland tumors at the Maxillofacial Unit of Barau Dikko Teaching Hospital, Kaduna, North-west, Nigeria over a period of 13years (January 2008 to December, 2020). Patients’ records were analyzed for age, sex, clinical presentation, investigations, surgical management, histological diagnosis and outcome of treatment.&#x0D; Results: A total of 55 patients with parotid gland tumors were seen. Age range was 12 - 75 years with a mean of 45.5 (SD± 0.7) years. The male: female ratio was found to be 1.1: 1. Pleomorphic adenoma was the commonest tumour (n=28, 50.9%). Four (7.3%) patients who had been on antiretroviral medications were seen with massive tumors. Superficial parotidectomy was the commonest surgical procedure carried out in these patients. Patients with malignancies were referred for post-surgical radiotherapy. High early recurrences were noticed in patients who were retroviral positive.&#x0D; Conclusion: Pleomorphic adenoma was commonest tumors treated and superficial parotidectomy was the commonest surgical procedure performed for the treatment of parotid gland tumors. Post-operative radiotherapy as an adjunct was carried out in cases with diagnosis of malignant lesions.&#x0D; &#x0D; &#x0D; &#x0D;

The distribution of parotid gland neoplasms in a veteran population.

ObjectiveSalivary gland tumors account for 6%–8% of head and neck neoplasms with the parotid gland as the most common primary site. Pleomorphic adenomas (PA) are considered the most common benign parotid gland neoplasms, followed by Warthin tumors (WT). The goal of this study was to investigate the distribution of parotid gland neoplasms among a United States veteran population.DesignRetrospective chart review.SettingWashington DC Veterans Affairs Medical Center.ParticipantsVeterans who underwent fine needle aspiration (FNA) for a parotid gland mass from 2000 to 2018 were included. Medical records were reviewed for gender, age, tobacco use, surgery date, and pathology results.Main outcome measuresChanges in the distribution of parotid neoplasms and tobacco use over an 18-year period.ResultsOf 141 patients with parotid gland masses, 86.5% (n = 122) were benign, 9.9% (n = 14) were malignant, and 3.5% (n = 5) were indeterminate. Of benign tumors, WT accounted for the majority at 51.6%, followed by PA at 40.2%. When stratified by decade (2000–2009 and 2010–2018), the proportion of WT compared to all other benign and malignant neoplasms increased from 31.6% to 53.6%, whereas the proportion of PA decreased from 36.8% to 33.3%. The rate of tobacco use was unchanged at approximately 32.0% among our cohort from 2000 to 2018.ConclusionAmong our cohort of veteran patients, WT was the most common benign parotid tumor and has increased in incidence over the last two decades despite an unchanged smoking rate.

Individualized parotidectomy to reduce the incidence of postoperative facial paralysis for primary benign parotid neoplasms

ObjectiveThe aim of this study was to evaluate the role of individualized parotidectomy to reduce the incidence of postoperative facial paralysis for primary benign parotid tumors. MethodsA total of 154 consecutive patients who underwent individualized parotidectomy for benign parotid gland neoplasms were retrospectively reviewed. We analyzed the incidence and the significant risk factors associated with postoperative facial paralysis after individualized parotidectomy. ResultsPostoperative transient FP was observed in 25 patients (16.2%). None of the patients developed a recurrence or permanent facial paralysis. Grade II facial nerve function was predominant (92.0%) and no patient had grade VI. Among the 25 patients, the facial nerve function of 93.6% of patients recovered in 3 months, and function had recovered in 100% of patients in 6 months. Tumor location, tumor size and surgery extent were the significant and independent risk factors associated with postoperative facial paralysis after individualized parotidectomy. ConclusionIndividualized parotidectomy can effectively reduce the incidence of postoperative facial paralysis and shorten the recovery time of facial nerve injury for primary benign parotid neoplasms.

Diagnostic performance of qualitative and radiomics approach to parotid gland tumors: which is the added benefit of texture analysis?

Objective:To investigate whether MRI-based texture analysis improves diagnostic performance for the diagnosis of parotid gland tumors compared to conventional radiological approach.Methods:Patients with parotid gland tumors who underwent salivary glands MRI between 2008 and 2019 were retrospectively selected. MRI analysis included a qualitative assessment by two radiologists (one of which subspecialized on head and neck imaging), and texture analysis on various sequences. Diagnostic performances including sensitivity, specificity, and area under the receiver operating characteristic curve (AUROC) of qualitative features, radiologists’ diagnosis, and radiomic models were evaluated.Results:Final study cohort included 57 patients with 74 tumors (27 pleomorphic adenomas, 40 Warthin tumors, 8 malignant tumors). Sensitivity, specificity, and AUROC for the diagnosis of malignancy were 75%, 97% and 0.860 for non-subspecialized radiologist, 100%, 94% and 0.970 for subspecialized radiologist and 57.2%, 93.4%, and 0.927 using a MRI radiomics model obtained combining texture analysis on various MRI sequences. Sensitivity, specificity, and AUROC for the differential diagnosis between pleomorphic adenoma and Warthin tumors were 81.5%, 70%, and 0.757 for non-subspecialized radiologist, 81.5%, 95% and 0.882 for subspecialized radiologist and 70.8%, 82.5%, and 0.808 using a MRI radiomics model based on texture analysis of T2 weighted sequence. A combined radiomics model obtained with all MRI sequences yielded a sensitivity of 91.5% for the diagnosis of pleomorphic adenoma.Conclusion:MRI qualitative radiologist assessment outperforms radiomic analysis for the diagnosis of malignancy. MRI predictive radiomics models improves the diagnostic performance of non-subspecialized radiologist for the differential diagnosis between pleomorphic adenoma and Warthin tumor, achieving similar performance to the subspecialized radiologist.Advances in knowledge:Radiologists outperform radiomic analysis for the diagnosis of malignant parotid gland tumors, with some MRI qualitative features such as ill-defined margins, perineural spread, invasion of adjacent structures and enlarged lymph nodes being highly specific for malignancy. A radiomic model based on texture analysis of T2 weighted images yields higher specificity for the diagnosis of pleomorphic adenoma compared to a radiologist non-subspecialized in head and neck radiology, thus minimizing false-positive pleomorphic adenoma diagnosis rate and reducing unnecessary surgical complications.

Treatment of Benign Lesion of Levels I or II of the Parotid Gland: Long Term Results of Partial Superficial Parotidectomy.

The correct surgical approach to benign parotid gland tumors is still matter of debate, it should be chosen considering the possibility of local recurrence or facial nerve complications in case of "not necessary" facial nerve dissection. In the era of minimally invasive surgery, more sparing approaches such as extracapsular dissection or partial superficial parotidectomy (PSP) are gaining popularity. The aim of the study is to present surgical results and long-term outcomes of PSP (level i or ii) in a large group of patients. Six hundred fifty-one patients who underwent parotid surgery between 2004 and 2020 were initially considered. Five hundred forty patients with benign lesions treated with PSP, enucleation, ECD were enrolled. Clinical features, surgical data, postoperative scarring, seroma, dehiscence, neuroma, outcomes as Frey syndrome, and delayed facial nerve dysfunction have been evaluated. 65.5% PSP, 25.2% enucleation, and 9.2% extracapsular dissection. No statistical difference in surgical time has been found (P 0.16). P > 0.05 for seroma, neuroma, Frey syndrome, and facial palsy between different type of surgery. Frey syndrome in PSP: 6/135 (4.4%) in 2004 to 2012 and 2/219 (0.9%) in 2013 to 2020. The reduction between periods is significant (P < 0.04). Recurrence: 0.8% (3/354) for PSP patients, 3.4% (5/ 136) in enucleation and 10% (5/50) in ECD (P = 0.02). Partial superficial parotidectomy can be considered a minimally invasive and quick procedure with low complication rate. Our data seem to support this statement (large case series and long-term follow-up).

Evaluation of MR imaging findings differentiating parotid basal cell adenomas from other parotid tumors

PurposeTo evaluate the usefulness of magnetic resonance imaging (MRI) to differentiate basal cell adenomas (BCAs) from other parotid tumors. MethodA total of 136 patients with histologically proven parotid gland tumors (13 BCAs, 66 pleomorphic adenomas [PAs], 30 Warthin tumors [WTs], and 27 parotid cancers [PCs]) who underwent a cervical MRI study between December 2011 and March 2019 were retrospectively enrolled. The MRI findings of the tumors were evaluated by two board-certified radiologists. ResultsAll 13 of the BCAs showed smooth margins, while 19 of the 27 PCs showed irregular margins (p < 0.0001). Eleven BCAs had some cystic components, and five were cyst-dominant. The BCAs had significantly more cystic components than the PAs (p = 0.0077). The mean apparent diffusion coefficient (ADC) value of the BCAs was 1.21 ± 0.20 × 10−3 mm2/sec, which was equivalent to that of the PCs (1.12 ± 0.25 × 10−3 mm2/sec, p = 0.76), significantly lower than that of the PAs (1.61 ± 0.32 × 10−3 mm2/sec, p < 0.0001), and significantly higher than that of the WTs (0.81 ± 0.19 × 10−3 mm2/sec, p = 0.0004). The plateau time-intensity curve (TIC) was the most common type for both BCAs and PCs, seen in 8 of 12 BCAs and 21 of 26 PCs, with no significant difference between these groups (p = 0.34). ConclusionsBCA should be considered a possibility when a parotid lesion has smooth margins with an entire capsule and includes a cystic component, even if the TIC and diffusion-weighted MR images suggest a malignant pattern.

Parotid Warthin's tumor: novel MR imaging score as diagnostic indicator

ObjectivesDespite known characteristic radiologic and clinical features, differentiation between Warthin's tumor (WT) and other parotid tumors remains challenging. The purpose of this study was to more precisely assess the MR imaging features of WT and to develop a scoring system combining the most specific characteristics. MethodsA total of 208 patients with parotid gland tumors and presurgical MRI were included. Tumors were divided into 5 histological subtypes, and different MRI features were compared between groups. An MRI scoring test was developed including MR parameters that contributed significantly in distinguishing WT from other tumors. ResultsThe best MRI features for differentiating between WTs from other tumors included bilaterality (P = 0.002), multifocality (P < 0.001), ADC values <905.1 (P < 0.001), and high signal intensity on T1-W images (P < 0.001). Six or more points on the 14-point scoring MRI scale was associated with an area under the curve of 0.99 (Accuracy of 98%), while a cut-off value of 7 indicated 100% specificity and 100% positive predictive value. ConclusionsIll-defined margins, low T1-W signal, and location in the upper 2/3 of the parotid gland excluded WTs in 100% of cases. The proposed scoring method allows WTs to be distinguished from other tumors with high accuracy. Key points•Despite known characteristic radiologic and clinical features, differentiation between Warthin's tumor (WT) and other parotid tumors remains challenging.•The best MRI features for differentiating between WTs from other tumors included bilaterality, multifocality, ADC values <905.1, and high signal intensity on T1-W images.•Six or more points on the 14-point scoring MRI scale was associated with an area under the curve of 0.99, while a cut-off value of 7 indicated 100% specificity and 100% positive predictive value.

Transoral Excision of a Large Accessory Parotid Gland Tumor.

Accessory parotid gland (APG) tumors account for 1% to 7% of all parotid gland neoplasms but are more likely to be malignant than main parotid gland tumors. Management of APG neoplasms entails surgical excision. Four primary approaches to resection have been described in the literature with varying facial nerve outcomes. We report a case of a 4-cm APG pleomorphic adenoma utilizing a transoral approach for excision without postoperative facial nerve injury. A transoral approach is known to mitigate patients' cosmetic concerns; however, prior reports utilized endoscopic assistance on patients with smaller tumors. We conclude that large APG tumors can be excised through a transoral approach without undue risk to the distal facial nerves, though this transoral approach ultimately may not be appropriate for malignant neoplasms or difficult dissections.

Advances in surgical approaches for the treatment of parotid tumors

Parotid gland tumor is the most common salivary gland tumor and surgery is the main treatment method. The conventional surgery for the treatment of parotid tumor is mostly performed by using large incision which often causes complications and aesthetic problems to patients. With the advancement of medical technology, deeper understanding of histopathology and anatomy by the surgeons, as well as patients' higher demands on aesthetics and functions, the surgical methods and incisions have been constantly improved. This review focuses on the evolution of surgical approaches and incisions for the treatment of parotid tumors and provides an outlook based on the preliminary application of endoscopically assisted parotid tumor resection.

Myoepidermal cell carcinoma of the deep lobe of parotid gland 16 years after superficial parotidectomy due to basal cell adenoma of the superficial lobe – case report

Authors present a case of 65-years old woman, who had a superficial parotidectomy due to basal cell adenoma in 2004, in 2020 rest of the parotid gland with tumor was resected, in post surgery histopathological was recognized as myoepidermal cell carcinoma. Authors also describe the clinical characteristic of neoplasm and multiple occurrences of different tumors in the same parotid gland.

Actinomycosis of the parotid gland. Challenges in diagnosis and treatment – case report

Introduction: Primary actinomycosis of the parotid gland is a rare infectious disease which can mimic a malignant process both clinically and diagnostically. Case report: We present a case report of actinomycosis of the parotid gland manifesting as a slowly growing tumor in the left neck region. Methods: Computer tomography, histopathologic examination Results: Total sialoadenectomy. Confirmed diagnosis of actinomycosis. Patient introduced to an infectious disease specialist. Conclusion: Although this location of actinomycosis is rare, the disease must be considered in the differential diagnosis of parotid gland tumors.

Improving Parotid Gland Tumor Segmentation and Classification Using Geometric Active Contour Model and Deep Neural Network Framework

Manual assessment of parotid gland status from magnetic resonance imaging is a subjective, time consuming and error prone process. Automatic image analysis methods offer the possibility to get consistent, objective and rapid diagnoses of parotid gland tumor. In this kind of cancer, a large variety in their characteristics, that brings various difficulties for traditional image analysis methods. In this paper, we propose an automatic method to perform both segmentation and classification of Parotid gland region in order to give quantitative assessment and uniform indicators of PGs status that will help pathologists in their diagnostic. The experimental result illustrates the high accuracy of the results of the proposed method compared to the ground truth. Furthermore, a comparative study with existing techniques is presented in order to demonstrate the efficiency and the superiority of the proposed method.