Parental Alcohol Use Research Articles

Longitudinal patterns of alcohol and cannabis use among US young adults: Correlates and implications for problematic health outcomes.

Alcohol and cannabis use are common during young adulthood. Less is known regarding correlates of alcohol-cannabis use patterns and related problematic health outcomes. Using longitudinal survey data (Fall 2018, 2019, 2020) from 2,194 young adults (YAs; ages 18-34), bivariate analyses and multivariable logistic regressions examined: (1) Wave 1 (W1) sociodemographics and psychosocial factors (i.e., adverse childhood experiences [ACEs], depressive symptoms, personality traits, parent and peer alcohol and cannabis use) in relation to W3 past-month use group (i.e., use of neither, alcohol only, cannabis only, both/co-use); and (2) W3 use group in relation to W5 problematic alcohol use (Alcohol Use Disorder Identification Test), problematic cannabis use (Cannabis Use Disorder Identification Test), and depressive/anxiety symptoms (Patient Health Questionnaire - 4 item). Overall, 42.3% reported W3 alcohol-only use, 34.9% co-use, 17.8% no use, and 5.0% cannabis-only use. Those reporting W3 co-use reported greater W1 extraversion, openness, friend alcohol/cannabis use, and were more likely to report parent cannabis use (vs. no use); reported less conscientiousness, greater friend cannabis use, and were more likely to report depressive symptoms and parent cannabis use (vs. alcohol-only use); and reported greater friend alcohol use, and were more likely to report parent alcohol use (vs. cannabis-only use). W3 co-use was associated with higher odds of W5 problematic alcohol use (vs. alcohol-only use) and problematic cannabis use (vs. cannabis-only use). Substance use messaging and interventions should consider YAs' alcohol-cannabis co-use and the unique correlates of such use.

Patterns of early childhood adversity and neighborhood deprivation predict unique challenges in adolescence: A UK birth cohort study.

This study applies a comprehensive bioecological perspective to address a significant gap in the childhood adversity literature by employing latent profile analysis to examine the impact of diverse combinations of early childhood adversities and protective factors on adolescent psychosocial and behavioral outcomes. Drawing from the United Kingdom's Millennium Cohort Study (N = 19,444), we identified eight unique profiles of early childhood adversity and protective factors. These profiles provide a nuanced understanding of adversity combinations and allow for differentiation between groups with similar profiles. Latent profile membership was a significant predictor of all adolescent outcome variables, indicating that profiles differed significantly from one another on psychosocial and behavioral outcomes (Wald values ranged from 10.10-623.22; p < .001). Some findings support the cumulative risk model, indicating that exposure to multiple early adversities increases the likelihood of adverse outcomes. However, we also found that specific adversities, such as parental psychopathology, parental alcohol use, and neighborhood deprivation, uniquely impact adolescent outcomes. This study highlights the necessity for tailored interventions and policies to support children with distinct early life experiences, emphasizing the importance of addressing both cumulative and specific adversities at multiple levels to prevent psychosocial and behavioral problems in adolescence.

Asymmetrical perceptions of tipping points in alcohol consumption: Lower perceived tolerance in oneself versus peer

Objective: The current study investigated how tipping points, a phenomenon in which an individual’s threshold for perceiving a change has been exceeded, may be asymmetrical between self-tipping points and those applied to others and how experiences with alcohol affect these judgments. Participants: Undergraduates (N = 300). Methods: Participants reported their drinking frequency, quantity, and parental alcohol use, and evaluated tipping points by assessing how many drinks over the course of how many days they would perceive as problematic alcohol use in an online survey. Results: Participants, on average, reported lower tipping points indicative of problematic drinking behaviors for themselves, as compared to their peers. Results also revealed that quantity of alcohol consumption as well as parental alcohol use and participant age contributed to determining problematic consumption tipping points. Conclusions: Considerations should be given to how these tipping point judgments may affect drinking behaviors. Additionally, there is evidence that current consumption may cloud these judgments.

Parental Patterns of Alcohol Consumption During the COVID-19 Pandemic: Scoping Review.

The declaration of the COVID-19 pandemic led to public health restrictions that impacted the lives of people across the globe. Parents were particularly burdened with balancing multiple responsibilities, such as working from home while caring for and educating their children. Alcohol use among parents is an area that warrants further exploration. This study aimed to investigate patterns of parental alcohol consumption during the COVID-19 pandemic, focusing on relative changes in the frequency and quantity of alcohol use compared to prepandemic use, nonparent adult samples, or both. A scoping review informed by the methodology of Arksey and O'Malley explored patterns of parental alcohol consumption during the COVID-19 pandemic. Searches were conducted in CINAHL, Ovid MEDLINE, PsycINFO, and Web of Science. Search terms were created using the Joanna Briggs Institute framework of Population, Concept, and Context, with the population being parents and the concept being alcohol consumption during the COVID-19 pandemic. The database search yielded 3568 articles, which were screened for eligibility. Of the 3568 articles, 40 (1.12%) met the inclusion criteria and were included in the scoping review. Findings indicated the following: (1) having children at home was a factor associated with parental patterns of alcohol use; (2) mixed findings regarding gender-related patterns of alcohol consumption; and (3) linkages between parental patterns of alcohol use and mental health symptoms of stress, depression, and anxiety. This scoping review revealed heterogeneous patterns in parental alcohol use across sociocultural contexts during the COVID-19 pandemic. Given the known harms of alcohol use, it is worthwhile for clinicians to assess parental drinking patterns and initiate conversations regarding moderation in alcohol use.

Parental Alcohol Exposures Associate with Lasting Mitochondrial Dysfunction and Accelerated Aging in a Mouse Model.

Although detrimental changes in mitochondrial morphology and function are widely described symptoms of fetal alcohol exposure, no studies have followed these mitochondrial deficits into adult life or determined if they predispose individuals with fetal alcohol spectrum disorders (FASDs) to accelerated biological aging. Here, we used a multiplex preclinical mouse model to compare markers of cellular senescence and age-related outcomes induced by maternal, paternal, and dual-parental alcohol exposures. We find that even in middle life (postnatal day 300), the adult offspring of alcohol-exposed parents exhibited significant increases in markers of stress-induced premature cellular senescence in the brain and liver, including an upregulation of cell cycle inhibitory proteins and increased senescence-associated β-galactosidase activity. Strikingly, in the male offspring, we observe an interaction between maternal and paternal alcohol use, with histological indicators of accelerated age-related liver disease in the dual-parental offspring exceeding those induced by either maternal or paternal alcohol use alone. Our studies indicate that chronic parental alcohol use causes enduring mitochondrial dysfunction in offspring, resulting in a reduced NAD+/NAHD ratio and altered expression of the NAD+-dependent deacetylases SIRT1 and SIRT3. These observations suggest that some aspects of FASDs may be linked to accelerated aging due to programmed changes in the regulation of mitochondrial function and cellular bioenergetics.

Good parent-child relationship protects against alcohol use in maltreated adolescent females carrying the MAOA-uVNTR susceptibility allele.

Risk-allele carriers of a Monoamine oxidase A (MAOA) gene, short-allele (MAOA-S) in males and long-allele (MAOA-L) in females, in the presence of a negative environment, are associated with alcohol misuse. Whether MAOA-S/L alleles also present susceptibility to a positive environment to mitigate the risk of alcohol misuse is unknown. Thus, we assessed the association of the three-way interaction of MAOA, maltreatment, and positive parent-child relationship with alcohol consumption among adolescents. This prospective study included 1416 adolescents (females: 59.88%) aged 16 - 19 years from Sweden, enrolled in the "Survey of Adolescent Life in Västmanland" in 2012. Adolescents self-reported alcohol consumption, maltreatment by a family (FM) or non-family member (NFM), parent-child relationship, and left saliva for MAOA genotyping. We observed sex-dependent results. Females carrying MAOA-L with FM or NFM and a good parent-child relationship reported lower alcohol consumption than those with an average or poor parent-child relationship. In males, the interactions were not significant. Results suggest MAOA-L in females, conventionally regarded as a "risk", is a "plasticity" allele as it is differentially susceptible to negative and positive environments. Results highlight the importance of a good parent-child relationship in mitigating the risk of alcohol misuse in maltreated individuals carrying genetic risk. However, the interactions were not significant after adjusting to several environmental and behavioural covariates, especially parent's alcohol use, negative parent-child relationship, and nicotine use (smoking and/or snus), suggesting predictor and outcome intersection. Future studies and frameworks for preventive strategies should consider these covariates together with alcohol consumption. More studies with larger sample sizes are needed to replicate the findings.

M47 - Parent Influence and Alcohol Use by Youth With Chronic Medical Conditions

M47 - Parent Influence and Alcohol Use by Youth With Chronic Medical Conditions

Risk of severe mood and anxiety disorders in the adult children of parents with alcohol use disorder: a nationwide cohort study

BackgroundGrowing up with parental alcohol use disorder (AUD) is a risk factor for psychiatric disorders. This study investigated the risk of mood disorders and of anxiety disorders in the adult...

Parental mental disorders in patients with comorbid schizophrenia and obsessive-compulsive disorder: a nationwide family-link study.

Schizophrenia is highly comorbid with obsessive-compulsive disorder (OCD); both conditions share numerous pathophysiological etiologies. We, thus, examined the risk of mental disorders in the parents of probands with schizophrenia, OCD, or both conditions. Between 2001 and 2011, we enrolled a nationwide cohort of 69,813 patients with schizophrenia, OCD, or both. The control cohort included 698,130 individuals matched for demographics. Poisson regression models were employed to examine the risk of six mental disorders in their parents, including schizophrenia, bipolar disorder, depressive disorder, OCD, alcohol use disorder, and substance use disorder. We stratified patients into schizophrenia-only, OCD-only, and dual-diagnosis groups, and the dual-diagnosis group was further divided into schizophrenia-first, OCD-first, and simultaneously diagnosed groups. Compared with controls, the schizophrenia, OCD, and dual-diagnosis groups had higher risks for the six mental disorders in their parents (range of odds ratio [OR] 1.50-7.83). The sub-analysis of the dual-diagnosis group showed that the schizophrenia-first, OCD-first, and simultaneously diagnosed groups had higher odds for schizophrenia, bipolar disorder, depressive disorder, and OCD (range of OR 1.64-6.45) in their parents than the control group; the simultaneously diagnosed and OCD-first diagnosed groups had a higher odds of parental substance use disorder, while the schizophrenia-first diagnosed group had a higher odds of parental alcohol use disorder. The interrelationship between OCD and schizophrenia is linked to bipolar disorder, depressive disorder, alcohol use disorder, and substance use disorder. The results have implications for mental health policy and future research.

Examining Parental Alcohol Use and Peer Relationships as Predictors of Substance Use Severity

In the United States, issues with substance use among adolescents has grown in its prevalence, and past research has shown a continuity in substance use amongst children with substance involved parents. In adolescence, young men tend to report higher rates of alcohol use when compared to young women. As such, we were interested in examining gender as a moderating factor on the relationship between parental alcohol use and substance use severity. Amazon’s MTurk was used to recruit 185 participants with a history of substance use to complete a series of surveys. Participants reported parental alcohol use during childhood and involvement with pro-social peers. Results revealed gender did not moderate the relationship between parental substance use and respondents’ self-reported substance use. However, there were strong correlations among substance use severity, parental alcohol use, and involvement with pro-social peers. Specifically, respondents who were the child of a mother who experienced problems with alcohol were 3.12 times more likely to have a severe SUD. This effect was not observed when paternal alcohol use was examined as a predictor of substance use severity (p=0.651). Respondents involved with pro-social peers are less likely to have a severe substance use disorder (p less than 0.001). Together, children whose mothers struggled with alcohol use were more likely to develop a severe substance use disorder. In contrast, having a father who struggled with alcohol use did not affect respondents’ involvement with substance use. Furthermore, having a peer support system reduces subsequent substance use, regardless of parental alcohol use.

Contextual Predictors of Sexual Abuse among Adolescent Girls, Kerala – A School Based Survey

Child sexual abuse is not only a frequent and arduous legal problem but also major public health challenges that is rampant both in the developed and developing countries. The likelihood that someone will sexually offend a child, often occurs in the context of a dysfunctional family environment, parental psychopathology, compromising parental alcohol and drug use, witnessing of domestic violence, divorce of biological parents, parental incarceration, parental suicide and low family support. The overall objective of the current study was to identify the predictors of sexual abuse among adolescent girls in Kerala. A Cross-Sectional design was amended for the study using a multistage sampling technique among 1087 adolescent girls belonging to eight and ninth standard. A predesigned, pretested questionnaire prepared by the investigator was administered during the school-based survey to estimate the prevalence and explore the predictors of sexual abuse among adolescent girls. The tool was validated by subject experts and content validity index was 0.9. The prevalence rate was 17.5% and a statistically significant association was found in all the predictor variables like family constellation, paternal psychopathology, maternal support, paternal substance abuse and parental social relation with the occurrence of sexual abuse. On further bivariate analysis with logistic regression only Maternal support (B value: 912; p value &lt;0.002**; OR (Beta): 2.490; CI: 1.408-4.406) and Paternal substance abuse (B value 1.242; p value &lt;0.001**; OR (Beta): 3.461; CI: 2.145-5.583) were found to be the true, strong predictors of sexual abuse among adolescent girls, Kerala. The results conclude that when a number of comorbid risk variables are assessed simultaneously, paternal substance abuse and maternal support were the contextual predictors of childhood sexual abuse.

The role of perceived parent drinking motives on alcohol use among adolescents with and without childhood attention-deficit/hyperactivity disorder.

Parent history of alcohol-related problems and antisocial behaviors contribute to adolescent alcohol use and are associated with offspring attention-deficit/hyperactivity disorder (ADHD). Youth with ADHD may be susceptible to intergenerational transmission of alcohol-related cognitions, which may model drinking motives that enhance risk for adolescent alcohol use. We examined whether childhood ADHD and parent history of alcohol use disorder, with or without antisociality, were associated with adolescents' perceptions of their parents' drinking motives and whether these perceptions predicted their alcohol use behaviors. Adolescents (N = 199; 56% with ADHD; Mage = 15.73) completed the Drinking Motives Questionnaire regarding perceptions of their parents' drinking motives. Participants subsequently reported their past-year alcohol use behaviors (Mage = 16.95). Parents reported their history of alcohol-related problems and antisocial symptoms. Covariates included adolescent gender (7% girls), race (9% self-identified Black), and parental education and marital status. Perceived parent drinking motives were highest for social and lowest for conformity motives, consistent with adult self-reports in the literature. Parent alcohol use and antisociality history predicted perceptions of parent drinking motives, and child ADHD only predicted perceptions of parent social drinking motives. Perceived parent drinking motives predicted adolescent alcohol use, but only among youth without ADHD. Findings reflect the potential importance of assessing adolescent perceptions of parent drinking motives for adolescents without ADHD and a possible need for supporting parents in communicating about their own alcohol use. Future research should consider alternative strategies (e.g., assessing implicit cognitions) for studying the link between alcohol-related cognitions and behaviors for adolescents with ADHD. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

The intergenerational continuity of alcohol use in a population sample

IntroductionResearch shows that parental alcohol use predicts youths’ alcohol use, but this intergenerational continuity may vary across countries, and little is known about its moderators. This study examined for the first time the intergenerational continuity in alcohol use in a population sample of families in Canada, and tested whether it varied by youths’ sex, family income, or family structure. MethodsWe used prospective longitudinal data on 1632 families from the Quebec Longitudinal Study of Child Development (QLSCD), a representative sample from the province of Quebec, Canada. Youths self-reported alcohol use and binge drinking frequency at seven timepoints from early adolescence to early adulthood. Predictors were mothers’ and fathers’ self-reported alcohol use from youths’ infancy through age 13, and mother-reported socioeconomic variables. ResultsWe identified three trajectories of alcohol use from ages 13 to 21 years: normative, late-onset and early-onset. Maternal alcohol use increased the youths' risk of following the early-onset trajectory of alcohol use, while both parents’ alcohol use decreased the odds of the youths following the late-onset trajectory, compared to the normative trajectory. Insufficient family income increased youths' risk of following either the early-onset or late-onset trajectories. Mothers’ and fathers’ alcohol use did not interact in predicting youths’ trajectory, and we found no moderating effects of the youths’ sex, insufficient income, or years as a single-parent family. ConclusionThe results suggest modest intergenerational continuity of alcohol use in Quebec families which may be used, with income insufficiency, to help identify at-risk children for targeted interventions.

Paternal Alcohol Consumption and Childhood Malnutrition: A Community-based Participatory Case-control Study among Adivasis in Rural South India.

Childhood malnutrition in India remains among the highest in the world. Adult alcohol consumption and severe malnutrition have increased among indigenous people in South India. However, the association between them is poorly understood. We aimed to evaluate this association, which could help design better intervention strategies. This case-control observational study was conducted in the Nilgiri district in South India. Cases included children aged 1-5 years with moderate malnutrition. Controls were defined as children in the same age group with normal weight-for-age. A questionnaire was used to collect data on demographics, socioeconomic status (SES), and parental education. The WHO Alcohol Use Disorders Identification Test (AUDIT) questionnaire was used to estimate parental alcohol use. Health-care workers collected data from within the community. The baseline demographics of the children in the control (n = 250) and case groups (n = 177) were similar. Paternal age and AUDIT scores were not different in the two groups. SES was lower in the malnourished group, while maternal education among cases was significantly lower. Maternal and paternal education were associated with childhood malnutrition (odds ratio [OR]: 0.728 [95% confidence interval (CI): 0.583-0.903] and OR: 0.753 [95% CI: 0.589-0.957], respectively). After adjustment for covariates, paternal alcohol use was associated with a higher risk of malnutrition (OR: 1.56 [95% CI: 1.00-2.47]), which SES partly mediated. Paternal alcohol consumption is associated with childhood malnutrition, partially mediated by lower SES. Furthermore, lower SES appeared to be strongly associated with paternal alcohol consumption.

Explanatory factors of polydrug use in mid-late teens and the relevance of information sources: Correlational and configurational assessment in Tarragona (Spain)

&lt;abstract&gt;&lt;sec&gt; &lt;title&gt;Background&lt;/title&gt; &lt;p&gt;Substance use among adolescents is a public health problem, and the simultaneous use of multiple substances aggravates this problem. Although the facilitators of specific substance use in adolescents have been widely investigated, polydrug use is a less common topic. Likewise, the role that the origin of the information available to adolescents regarding substance use plays in relation to polydrug use is practically unexplored.&lt;/p&gt; &lt;/sec&gt;&lt;sec&gt; &lt;title&gt;Objectives&lt;/title&gt; &lt;p&gt;This work analyzed the relevance of the origin of the information sources available to adolescents regarding substance use, among which we distinguished those that were monitored (or supervised) by public agencies from those that were unmonitored (or unsupervised) in the consumption of more than one substance. As control variables, we considered three individual factors and four environmental factors. The relevance of these sources was analysed from a dual perspective: on the one hand, their statistical relevance was measured, and on the other hand, how they combined with the control variables was analysed to identify risk and risk-free profiles in substance poly-drug use.&lt;/p&gt; &lt;/sec&gt;&lt;sec&gt; &lt;title&gt;Methods&lt;/title&gt; &lt;p&gt;This paper utilized a sample of &lt;italic&gt;N&lt;/italic&gt; = 573 adolescents aged ≥17 years. This sample was collected from a survey administered in the spring of 2023. We examined the impact of unmonitored information sources (peers, siblings, and the Internet) and supervised sources (school, parents, and media) on the combined consumption of alcohol, tobacco, and cannabis. Additionally, we took three individual factors (gender, early onset of alcohol, and tobacco use) and four environmental factors (parental control, alcohol, tobacco, and cannabis use among peers) into account as control variables. Initially, we conducted a regression analysis to adjust for the impact of these factors on polydrug use. Subsequently, we employed a fuzzy set qualitative analysis (fsQCA) to investigate how predictor factors combined with the formation of adolescent profiles associated with polydrug consumption and nonconsumption.&lt;/p&gt; &lt;/sec&gt;&lt;sec&gt; &lt;title&gt;Results&lt;/title&gt; &lt;p&gt;Unmonitored information sources were associated with a greater incidence of poly consumption, with ORs of 1.703 and p values of 0.004. However, the protective effects of regulated information sources remained ambiguous. Among the variables positively linked with of polydrug use, are female sex (&lt;italic&gt;OR&lt;/italic&gt; = 1.329, &lt;italic&gt;p&lt;/italic&gt; = 0.0076), early alcohol consumption (&lt;italic&gt;OR&lt;/italic&gt; = 4.680, &lt;italic&gt;p&lt;/italic&gt; &amp;lt; 0.0001), and early tobacco consumption (&lt;italic&gt;OR&lt;/italic&gt; = 3.242, &lt;italic&gt;p&lt;/italic&gt; &amp;lt; 0.001) were the most important. Peer drinking (&lt;italic&gt;OR&lt;/italic&gt; = 1.556, &lt;italic&gt;p&lt;/italic&gt; = 0.0187) and peer cannabis use (&lt;italic&gt;OR&lt;/italic&gt; = 1.351, &lt;italic&gt;p&lt;/italic&gt; = 0.0226) were also significantly correlated. The use of the fsQCA made it possible to identify the profiles of adolescents associated to polysubstance use and non-use. The conditions of the configurations that explained use were characterized by an early onset of the joint consumption of tobacco and alcohol. The profile of non-consuming adolescents is that of adolescents whose peers do not use tobacco or cannabis and who have parental control and monitored sources.&lt;/p&gt; &lt;/sec&gt;&lt;/abstract&gt;

Prevalence, risk and protective factors of substance use amongst adolescents living in peri‐urban communities in Abuja, Nigeria

AbstractAdolescents living in peri‐urban communities are more vulnerable to risky behaviours such as substance use. This was a cross‐sectional study carried out to determine the prevalence, risk and protective factors of adolescent substance use in peri‐urban communities in Abuja. Data on lifetime and current substance use were collected using the Youth Risk Behaviour Survey Instrument. Data on risk and protective factors of adolescent substance use, based on the Problem Behaviour Theory, were also collected. Using the SPSS software, descriptive analysis was conducted to summarise the data. Bivariate analysis was conducted using chi‐square and independent t‐tests, and multivariate analysis was conducted using logistic regression. A p‐value of less than 0.05 was considered statistically significant. The prevalence of lifetime substance use was 22.8%, whilst current substance use was 18.5%. The consumption of mixed drinks was the most currently used form substance at 8.1%, followed by alcohol (5.7%) and shisha (4.7%). Multivariate analysis showed that self‐esteem (0.007), delinquency (p &lt; 0.001) and parent alcohol use (p = 0.045) were independently associated with adolescent substance use. There is a high prevalence of substance use amongst adolescents living in peri‐urban communities in Abuja, Nigeria, as well as a new pattern of substance use consumption. The findings showed that some risk factors identified by the problem behaviour theory were independently associated with adolescent substance use, whilst the protective factors were not. There is a dire need for adolescent substance use interventions in peri‐urban communities that addresses certain risk factors.

Parental Smoking, Water Pipe and Alcohol Use Before Childbirth and Multiple Sclerosis Onset: A Case-Control Study

Parental Smoking, Water Pipe and Alcohol Use Before Childbirth and Multiple Sclerosis Onset: A Case-Control Study

23 The Impact of Parental History of Substance Use on Preadolescent Rewarding Processing in the ABCD Study

Objective:Parental history (PH) of problematic substance use has been identified as a risk factor for adolescent substance use, which can lead to increased use in adulthood. Researchers hypothesize that individuals with PH exhibit premorbid differences in their reward processing, increasing their likelihood of engaging in reward-driven behavior. Studies have shown that preadolescents with PH have greater activation in their putamen and nucleus accumbens (NA); however, most research has only investigated PH of alcohol use (PHA), not PH of drug use (PHD). Additionally, limited research has assessed whether reward processing develops differently among youth with (PH+) to youth without (PH-). The present study utilizes the national, prospective Adolescent Brain Cognitive Development SM (ABCD) Study to examine whether reward anticipation in the nucleus accumbens (NA) differs in preadolescents with and without parental substance use history and whether patterns of reward anticipation change over time during a two-year follow-up period. Further, it will also examine whether PHA and PHD predict similar activation patterns.Participants and Methods:The current sample (N=6,600, Mage = 10.9; range = 9-13.8 years old; 46.7% female) was drawn from the national ABCD Study. To assess reward processing, the Monetary Incentive Delay Task (MID), a fMRI task-based paradigm, was administered at baseline and 2 year follow-up. The primary regions of interest (ROI) were the left and right NA and neutral vs anticipation of large rewards was the selected contrast. The Family History Assessment was used to assess problematic parental alcohol and drug use for both parents, with scores ranging from 0-2, with two indicating that both parents demonstrate problematic use. Three PH contrasts (PH- vs.PH+1, PH-vs.PH+2, &amp; PH+1 vs. PH+2) were created for each group (PHA and PHD) (Martz et al., 2022). Separate linear mixed-effect models with predictors variables (parental contrasts, timepoint, and parental contrasts-by-time-point) and covariates (age, sex, race/ethnicity, income, parental education, parental warmth, parental monitoring, and the random effects of MRI model, family status, and subject) were run to predict reward anticipation.Results:Results indicated that PHA and,not PHD, was predictive of reward anticipation. PHA+1 youth showed greater activation in the l-NA (b= .02827, p= .03) and r-NA (b= .03476, p=.005), compared to PH- youth. Additionally, PHA+1 youth showed greater activation in the r-NA (b=-.07029, p=.008) compared to PHA+2 youth, but not in the l-NA. Those with PHA+2 demonstrated blunted activity in both the l-NA (b= -.07244, p=.02) and right nucleus accumbens (b= -.1091, p=001) when compared to those with PH-. No interactions with time were found.Conclusions:Preadolescents with a PHA+ for both parents had blunted activity in reward anticipation, conferring a unique risk not seen in youth with only one parent with problematic alcohol use, or in youth with a PH of drug use. Future research should attempt to disentangle both genetic and environmental factors that may explain these discrepancies in reward processing, as well as the protective factors that may mitigate it. The current study found no interaction between PHA+ and time, suggesting that during preadolescents, the pattern of reward functioning remains consistent, but future work should assess if this pattern holds up across adolescence

The relative effects of parental alcohol use disorder and maltreatment on offspring alcohol use: Unique pathways of risk.

Childhood adversity represents a robust risk factor for the development of harmful substance use. Although a range of empirical studies have examined the consequences of multiple forms of adversity (i.e., childhood maltreatment, parental alcohol use disorder [AUD]), there is a dearth of information on the relative effects of each form of adversity when considered simultaneously. The current study utilizes structural equation modeling to investigate three unique and amplifying pathways from parental AUD and maltreatment exposure to offspring alcohol use as emerging adults: (1) childhood externalizing symptomatology, (2) internalizing symptomatology, and (3) affiliation with substance-using peers and siblings. Participants (N = 422) were drawn from a longitudinal follow-up study of emerging adults who participated in a research summer camp program as children. Wave 1 of the study included 674 school-aged children with and without maltreatment histories. Results indicated that chronic maltreatment, over and above the effect of parent AUD, was uniquely associated with greater childhood conduct problems and depressive symptomatology. Mother alcohol dependence was uniquely associated with greater affiliation with substance-using peers and siblings, which in turn predicted greater alcohol use as emerging adults. Results support peer and sibling affiliation as a key mechanism in the intergenerational transmission of substance use between mothers and offspring.

Parent-Youth Relationships and Youth Alcohol Use: The Moderating Role of Parental Alcohol Use

AbstractPrevious studies have shown that strong parent-youth relationships serve as a protective factor inhibiting early alcohol use onset among youth, while parental alcohol use as a risk factor. However, little is known about the moderating effect of parental alcohol use on the relationship between parent-youth relationships and youth alcohol use. Using a nationally representative sample of 2,667 junior high school students entering eighth grade (aged 14 to 15) in Taiwan, this study examined the moderating role of parent use of alcohol on the relationship between parent-youth relationships and youth alcohol use. Results show that parent-youth relationship only remains a protective factor for youths whose parents do not drink alcohol; parent-youth relationship increases the likelihood of youth alcohol use if the parents use alcohol. Results suggest that parents and practitioners aiming to prevent early alcohol use onset among junior high school students should be aware of the potential influence of parental alcohol use behaviors and educate youths to assess their health behaviors regardless of their parents’ alcohol use behaviors.