Parasitological Studies Research Articles

Pathological, immunological and parasitological study of sheep vaccinated with the recombinant protein 14-3-3z and experimentally infected with Fasciola hepatica

In this study, the immunogenicity and protective capacity of a new recombinant vaccine candidate, the rFh14-3-3z protein was analysed in sheep experimentally challenged with Fasciola hepatica, in terms of fluke burden, faecal egg counts, hepatic damage and humoral immune response. Three groups of 8 animals each were used for study, group 1 was immunised with the rFh14-3-3z in Montanide adjuvant, whereas group 2 and 3 remained as adjuvant control and infection control groups, respectively. The parasitological analysis showed that no significant reduction in fluke burden, fluke size and faecal egg counts was detected. The extent of hepatic damage was very similar between groups. Nonetheless, animals immunised with the rFh14-3-3z protein induced the development of specific IgG1 and IgG2, being the IgG1 the predominant antibody; which confirms the immunogenicity of this protein in sheep. This is the first report of the 14-3-3z proteins as vaccine against the infection with F. hepatica.

Chronic lead intoxication decreases intestinal helminth species richness and infection intensity in mallards (Anas platyrhynchos)

Lead (Pb) pollution of aquatic habitats is a known threat to vertebrate health. Depending on Pb dosage, resulting symptoms can be chronic (sublethal) or acute (lethal). While acute exposure results in death of the animal, chronic sublethal exposure can also have consequences, reproduction, antioxidant defense and immunity being the most affected traits. While a great deal is known about Pb intoxication on avian health, relatively little is known about how intoxication impacts parasites dependent on their avian hosts. The effect of Pb on intestinal helminth species richness and infection intensity was investigated in mallards (Anas platyrhynchos, n = 100) from German waters. Coracoid bones were used to measure chronic Pb exposure. Intestinal helminths were characterized morphologically. Molecular approaches were also applied to identify poorly morphologically preserved parasites to obtain sequence data (cox1 gene) for species identification and future parasitological studies. Parasite species richness and infection intensity was found to be significantly lower in birds with higher chronic Pb levels suggesting both host and parasites respond to Pb exposure. Altered immune modulation in the avian host may be the underlying mechanisms of Pb triggered decrease of parasites. However, it also likely reflects differences in the susceptibility of different helminths to Pb. Cestode and acanthocephala species richness were particularly impacted by Pb exposure. We conclude that, Pb intoxication may both negatively impact avian host and parasite diversity in aquatic habitats.

New Data on Parasitic Fauna of Bream Abramis brama (Linnaeus, 1758) of the Lower Irtysh (Acquired Part of the Range)

The results of a parasitological study of bream Abramis brama (Linnaeus, 1758) from the Lower Irtysh basin are presented. Twelve species of parasites were found: infusoria (2 species), monogeneans (4 species), cestodes (1 species), and trematodes (5 species). Six of them have a direct life cycle, and six species develop with a change of hosts. Specific parasites for bream are Gyrodactylus elegans, Dactylogyrus wunderi, D. falcatus, and D. zandti. For the first time, Dactylogyrus falcatus is recorded in the Ob basin, and D. zandti and D. wunderi are recorded in the Lower Irtysh basin. The infestation of bream with metacercariae Opisthorchis felineus is established (the extent of invasion is 55.5%, the abundance index is 2.6).

Structure of parasite communities in urban environments: the case of helminths in synanthropic rodents.

Identifying patterns with sufficient predictive power is a constant challenge for ecologists to address ecological problems related to species conservation, pollution or infectious disease control. During the last years, the amounts of parasitological studies in this sense increased, but they are still scarce in urban environments. The main aim of this study was to investigate if the helminth communities of urban rodents are structured within host assembly (compound community) or they are a result of random events occurring at each individual host scale (infracommunity). A total of 203 rodents belonging to four species, Rattus rattus (Linnaeus), Rattus norvegicus (Berkenhout), Mus musculus Linnaeus and the native Oligoryzomys flavescens (Waterhouse) and captured in different landscape units of the City of Buenos Aires (industrial-residential neighbourhoods, shantytowns and parklands) were analysed. The results showed that infracommunities could be grouped according to composition and relative abundances and that they respond to the structure of the host community. Thus, the component communities defined in this study could be identified as subsets of the compound community (rodent assemblage) and infracommunities (each host) as random samples within each one. Quantitative differences among component communities were denoted by comparing the infection levels of helminths described as central species. Therefore, infracommunities of R. norvegicus and O. flavescens were the most predictable because of the high abundance of the nematodes Heterakis spumosa Schneider, 1866 and Nippostrongylus brasiliensis (Travassos, 1914), and Stilestrongylus flavescens (Sutton et Durette-Desset, 1991), respectively. Several mechanisms contribute to complexity of the structure of parasite communities, where specific parasites, definitive and intermediate hosts, and environmental and anthropogenic factors all play a role in the dynamics of the compound community.

A model of pulmonary toxoplasmosis in rats as potential impact on immune deficient diseases

Toxoplasma gondii is an obligate intracellular zoonotic protozoan. Pulmonary involvement is common in immunocompromised hosts but rarely occurs in immunocompetent ones. Rat pulmonary involvement could be considered as a good representative model for study of human toxoplasmosis infection to either acute toxoplasmosis, chronic toxoplasmosis, or disseminated toxoplasmosis in human immunodeficiency virus (HIV) patients. Forty Swiss-Webster rats were divided into four groups each ten rats: group 1, non-infected and untreated (normal); group 2, acute infected non-treated; and groups 3 and 4, chronic infected non-treated and corticosteroid treated respectively. Lung tissue and blood samples were taken during acute and chronic stages for parasitological and histopathological study and serological assay. Acute and chronic states revealed the presence of viable toxoplasma tachyzoites and bradyzoites in lung tissue respectively. Serological assay showed different results in acute and chronic infections. The histopathological changes in acute rat group showed that per alveolar septa has been swollen due to swelling of the pneumocystis type I and II and the lining cells of the alveoli became low cuboidal in shape. The histopathological changes in chronic untreated rat group showed that the majority of alveolar walls were thickened due to swelling of the alveolar epithelial cells and mononuclear inflammatory cells and the bronchioles due to hyperplasia of its lining epithelium. Some of the blood vessel wall contained large number of chronic Toxoplasma cysts and surrounded by mononuclear cells. While chronic corticosteroid-treated rat group showed perivascular and alveolar edema with congested per alveolar blood capillaries and alveolar edema with compensatory emphysema of some others. The study concluded that toxoplasmosis is a great of interest, serious, and often a life-threatening disease in immune-deficient patients and sometimes in immunocompetent ones. Pulmonary toxoplasmosis should be considered in the differential diagnosis in potentially HIV-infected patients with respiratory symptoms and bilateral pulmonary infiltrates. Early diagnosis and initiating specific good therapy is essential.

Epidemological and Parasitological Studies on Hydatidosis in Kirkuk Province, Iraq

Epidemological and Parasitological Studies on Hydatidosis in Kirkuk Province, Iraq

Effects of anthropogenic stress on the presence of parasites in a threatened population of black howler monkeys (Alouatta pigra)

Habitat disturbance disrupts the ecological interactions of mammals, leading to negative consequences for biodiversity. In particular, it is suggested that parasite-host interactions are affected in tropical ecosystems, with parasite diversity reduced as environmental perturbations take place. In this study, we examined whether the disruption of tropical forests affects the presence of parasites in a population of endangered black howler monkeys (Alouatta pigra) that inhabits a highly fragmented landscape in Balancan, Tabasco, Mexico. Our working hypothesis was that increased forest perturbation would negatively affect the incidence of parasitic infections (parasite presence and richness) in black howler monkeys. We conducted a parasitological study and collected stool samples from 65 adult individuals living in 30 forest fragments across a disturbance gradient. We recovered parasite eggs from stool samples using flotation and sedimentation techniques. We selected fragment size and distance from each forest fragment to the nearest village as measures of forest perturbation. We analyzed the effects of forest perturbation on parasite presence and richness using generalized linear models. Other driving factors such as seasonality, host density, and sex were also considered in the models. Gastrointestinal parasite infection was positively related to distance between forest fragments and the nearest human settlement (β = 0.55 ± SE 0.28, z = 2.0, P = 0.05). No effects of fragment size or any other variable considered in the model on the presence of parasite infection were observed. Parasite richness was not affected by any of the measures of forest perturbation, nor by any other variables considered in the analysis. Our findings suggest that an increase in forest perturbation may negatively affect the probability of parasite infection in black howler monkeys, as individuals living in close proximity to human settlements showed a lower presence of parasites. We proposed that the low parasite infection rates recorded in this monkey population reflect synergistic effects associated with both the alteration of the parasite-primate network, as well as the low resilience of parasites to thrive in a disrupted ecosystem.

Parasites of Neotropical Primates: A Review

The study of parasites is of great relevance to primatology given their ecological significance and their effects on primate demography, behavior, and evolution. Moreover, assessing the vulnerability of endangered species to parasitic infections is important in developing appropriate conservation strategies. We conducted an intensive bibliographical search to synthesize the available information about the parasites of Neotropical primates. We analyzed the host and parasite taxonomic coverage of the available studies, examined the advantages and disadvantages of the diagnostic techniques employed, identified information gaps that need to be addressed, and recommend future directions in the parasitological research of Neotropical primates. Researchers have reported 276 parasite taxa, including endo- and ectoparasites, in 21 of the 22 genera of Neotropical primates. Of these, 42 parasite species have also been reported in humans, although this number may be inaccurate owing to misidentification. The parasites of 50% of Neotropical primate species are completely unknown, and 32% of the parasites recorded in these hosts have not been identified to the species level. Information regarding ectoparasites is particularly limited. We need to develop methods that enhance parasite diagnosis accuracy when using noninvasive samples, and the incorporation of molecular techniques in routine procedures should be a priority in parasitological studies of Neotropical primates. An integrative approach in which veterinarians, primatologists, and parasitologists collaborate in the identification and treatment of parasites of Neotropical primates is essential to achieve significant progress in this field.

Expansion of the Range of the Black Sea Snail Lithoglyphus naticoides (C. Pfieffer, 1828) (Mollusca: Gastropoda: Lithoglyphidae) and Associated Trematode Species in the Upper Volga Basin

The Black Sea snail Lithoglyphus naticoides (C. Pfieffer, 1828) (Mollusca: Gastropoda: Lithoglyphidae) was first recorded in the Uglich Reservoir in the summer of 2013. By 2015, several new local settlements of the snail had been found in the Uglich and Rybinsk reservoirs, indicating its successful naturalization in the Upper Volga basin. Parasitological studies of L. naticoides from these habitats reveal the parthenitae of three trematode species.

Prevalence and risk factors of intestinal Helminthiasis among the children of Begun Bari slum, Tejgaon, Dhaka

A cross sectional parasitological study was conducted among the underprivileged children of Begun Bari slum, Tejgaon, Dhaka during January 2015 to December 2016. Fecal samples were collected and then processed through formaldehyde-ether concentration technique. Prevalent helminths were Ascaris lumbricoides (27.68%), Trichuris trichiura (21.57%) and Taenia saginata (18.24%). Male children were at high risk for helminth infection than females. The highest prevalence of A. lumbricoides (42.11%) was observed among the children aged 10 -12 years and T. saginata (35.71%) among 13 - 15 years. The prevalence of A. lumbricoides (23%) was the uppermost in the winter (23%) and the lowest in the rainy season (4.3%). Children of illiterate mothers (91.89%), bare footers (76.03%) and mud floor residents (76.43%) were more prone to helminth infections (p < 0.05).Bangladesh J. Zool. 45(2): 123-129, 2017

Tetrameres globosa (Linstow, 1879) (Nematoda, Tetrameridae) – a nematode of the Eurasian coot Fulica atra (Linnaeus, 1758) recorded for the first time in Poland

During parasitological studies of 23 Eurasian coot Fulica atra (Linnaeus, 1758), 91 nematodes were isolated. Three of them, found in the proventriculus, were identified as Tetrameres globosa (Linstow, 1879). This paper presents the morphological characteristics of the discovered males of T. globosa.

Optimum Sample Size to Estimate Mean Parasite Abundance in Fish Parasite Surveys.

SummaryTo reach ethically and scientifically valid mean abundance values in parasitological and epidemiological studies this paper considers analytic and simulation approaches for sample size determination. The sample size estimation was carried out by applying mathematical formula with predetermined precision level and parameter of the negative binomial distribution estimated from the empirical data. A simulation approach to optimum sample size determination aimed at the estimation of true value of the mean abundance and its confidence interval (CI) was based on the Bag of Little Bootstraps (BLB). The abundance of two species of monogenean parasites Ligophorus cephali and L. mediterraneus from Mugil cephalus across the Azov-Black Seas localities were subjected to the analysis. The dispersion pattern of both helminth species could be characterized as a highly aggregated distribution with the variance being substantially larger than the mean abundance. The holistic approach applied here offers a wide range of appropriate methods in searching for the optimum sample size and the understanding about the expected precision level of the mean. Given the superior performance of the BLB relative to formulae with its few assumptions, the bootstrap procedure is the preferred method. Two important assessments were performed in the present study: i) based on CIs width a reasonable precision level for the mean abundance in parasitological surveys of Ligophorus spp. could be chosen between 0.8 and 0.5 with 1.6 and 1x mean of the CIs width, and ii) the sample size equal 80 or more host individuals allows accurate and precise estimation of mean abundance. Meanwhile for the host sample size in range between 25 and 40 individuals, the median estimates showed minimal bias but the sampling distribution skewed to the low values; a sample size of 10 host individuals yielded to unreliable estimates.

Prevalence of Parasitic Infections in Surgically Removed Appendices: Parasitological and Histopathological Studies.

SummaryIntestinal parasites may cause symptoms similar to acute appendicitis. Moreover, the diagnosis of parasitic infections is only done by post-operative histopathological examination of the appendices. Therefore, our aims are to assess the prevalence of intestinal parasitic infections among patients who were be appendectomized at Tanta Hospitals, Egypt and to investigate the possible association between these parasitic infections and appendicitis. To achieve these objectives, we performed a cross-sectional study including 65 patients chosen randomly who had undergone appendectomy over a period of one year from Oct 2015 to Oct 2016. Demographic data were retrieved. Complete blood picture was done. Moreover, appendiceal faecolith were examined macroscopically then by direct smear examination, formol-ether concentration technique, modified Ziehl-Nelseen stain and rapid immunochromatographic test. Histopathological examination of resected appendices was done. We found that parasitic infections were detected in 24.6 % of examined cases. Most of parasitic infections were prevalent in patients belonging to the school age group. Different parasitic infections were detected in the faecolith specimens. Moreover, Enterobious vermicularis adult female and Schistosoma mansoni granuloma were detected in histopathological sections. Also, a spectrum of pathological changes in the appendices was found ranging from lymphoid hyperplasia to acute inflammation with peritonitis. In conclusion, intestinal parasites may cause clinical picture similar to that of acute appendicitis. Therefore, careful attention to clinical history, stool examination and high eosinophilia may aid diagnosis and avoid unnecessary appendectomy. Moreover, the presence of different parasitic stages in the narrow lumen of the appendix may have a role in the development of appendicitis and this needs further studies.

Human Parasitic Diseases in Bulgaria in Between 2013-2014.

Background:In Bulgaria, more than 20 autochthonous human parasitic infections have been described and some of them are widespread. Over 50 imported protozoan and helminthic infections represent diagnostic and therapeutic challenges and pose epidemiological risks due to the possibility of local transmission.Aims:To establish the distribution of autochthonous and imported parasitic diseases among the population of the country over a 2-year period (2013-2014) and to evaluate their significance in the public health system.Study Design:Cross sectional study.Methods:We used the annual reports by regional health inspectorates and data from the National Reference Laboratory at the National Centre of Infectious and Parasitic Diseases on all individuals infected with parasitic diseases in the country. Prevalence was calculated for parasitic diseases with few or absent clinical manifestations (oligosymptomatic or asymptomatic infections). Incidence per 100.000 was calculated for diseases with an overt clinical picture or those that required hospitalisation and specialised medical interventions (e.g. surgery).Results:During the research period, parasitological studies were conducted on 1441.244 persons, and parasitic infections were diagnosed in 22.039 individuals. Distribution of various parasitic pathogens among the population displayed statistically significant differences in prevalence for some intestinal parasites (enterobiasis 0.81%, giardiasis 0.34% and blastocystosis 0.22%). For certain zoonotic diseases such as cystic echinococcosis (average incidence of 3.99 per 100.000) and trichinellosis (average incidence of 0.8 per 100.000), the incidence exceeds several times the annual incidence recorded in the European Union.Conclusion:Parasitic diseases still pose a substantial problem with social and medical impacts on the residents of our country. Improved efficiency regarding autochthonous and imported parasitic diseases is essential in providing the public health system the tools it needs to combat these diseases. Attention should be focused on the various imported vector-borne parasitic diseases (e.g. malaria and cutaneous leishmaniasis) for which the country is potentially endemic.

Strongyloidiasis Outside Endemic Areas: Long-term Parasitological and Clinical Follow-up After Ivermectin Treatment.

Strongyloides stercoralis affects 30-100 million people worldwide. The first-line therapy is ivermectin. Cure is defined as the absence of larvae by parasitological methods 1 year after treatment. To date, no longitudinal parasitological studies for longer periods of time have been conducted to confirm its cure. Here, we evaluated treatment response in long-term follow-up patients with chronic infection using parasitological and molecular methods for larvae or DNA detection. A prospective, descriptive, observational study was conducted between January 2009 and September 2015 in Buenos Aires, Argentina. Twenty-one patients with S. stercoralis diagnosis were evaluated 30, 60, and 90 days as well as 1, 2, 3, and/or 4 years after treatment by conventional methods (fresh stool, Ritchie method, agar plate culture), S. stercoralis-specific polymerase chain reaction (PCR) in stool DNA, and eosinophil values. During follow-up, larvae were detected by conventional methods in 14 of 21 patients. This parasitological reactivation was observed starting 30 days posttreatment (dpt) and then at different times since 90 dpt. Eosinophil values decreased (P = .001) 30 days after treatment, but their levels were neither associated with nor predicted these reactivations. However, S. stercoralis DNA was detected by PCR in all patients, both in their first and subsequent stool samples, thus reflecting the poor efficacy of ivermectin at eradicating parasite from host tissues. Asymptomatic eosinophilia was the most frequent clinical form among chronically infected patients. These results suggest that the parasitological cure is unlikely. Strongyloidiasis must be considered a chronic infection and ivermectin administration schedules should be reevaluated.

Parasitofauna of the Caspian salmon (Salmo trutta caspius Kessler) at the salmon fish hatcheries of Azerbaijan for the period of their existence

The Caspian salmon is included in the Red List of Azerbaijan with the international status CR (Critically Endangered). The article presents the comparative analysis of the parasitofauna of the Caspian salmon (Salmo trutta caspius Kessler) during the period of its existence (1955–2015) at the hatcheries of Azerbaijan (Chaykend and Chukhur-Gabala salmon fish hatcheries). When comparing the quantitative index of parasitofauna for the first years after the creation of the salmon fish hatcheries (9 species of parasites) and studies carried out by the authors (7 species of parasites), it was revealed that the change was insignificant. However, significant changes in the species composition of the parasitofauna of the Caspian salmon were found. The parasites Chilodonella piscicola, Trichodina truttae, Eubothrium crassum, Rhabdochona gnedini, Cystidicoloides tenuissima, Piscicola geometra found in the first years of the salmon fish hatcheries were not recorded by the authors, and Bunodera luciopercae, Metechinorhynchus baeri, Pomphorhynchus laevis, Glochidium sp. revealed in recent studies were not observed in the early years. The dominant groups of parasites of the Caspian salmon were revealed. A systematic review of all parasites of salmonids found during this period is presented. Three species of parasites were noted for the first time in the territory of Azerbaijan for the Caspian salmon in the salmon fish hatcheries (trematode Bunodera luciopercae, acanthochephala Pomphorhynchus laevis and mollusk Glochidium sp.). The authors specifically noted parasites identified from 2005 to 2015 that are conditionally pathogenic for the Caspian salmon and capable to cause significant damage to the salmon hatcheries: Costia necatrix, Ichthyophthyrius multifiliis, Gyrodactylus derjavini, Metechinorhynchus baeri, Pomphorhynchus leavis, Bunodera luciopercae. The authors note that during the period of parasitological studies of the Caspian salmon in salmon hatcheries in Azerbaijan, pathogenic parasites for humans have not been found.

НОВЫЕ ДАННЫЕ ПО ЭНДОБИОНТАМ ХИТОНОВ (MOLLUSCA), "Паразитология"

The strictly marine benthic Polyplacophora serve as basibionts for a wide spectrum of endobiotic taxa. Here we present detailed observations of three yet unrecorded polyplacophoran - copepod endobioses, with highly modified females and males, which not fit into the current concept of the Chitonophilidae, to which we attribute them. Furthermore, presumed larvae of two of them show that even the ontogeny to the adult copepods is not strictly in line with the present understanding of this family. Range extension and additional morphological details are also presented for the chitonophilid copepod Tesonesma reniformis Avdeev and Sirenko, 1994. We also show the double infestation with chitonophilid copepods in a single basibiont, more specific the new record refers to a mesobiotic Ischnochitonika sp. and to one of the three endobiotic chitonophilids. Representatives of usually free-living nematodes are shown to occur also in two different basibionts. The last new record refers to a tentatively identified protist found in a North Pacific chiton. In an updated summary of yet known endobionts of Polyplacophora we not only refer to old literature records but indicate further records, which were out of focus of the present study. The compilation of 35 endobiotic records shows that only 3.1 % of the currently known extant polyplacophorans, which represent 16 genera within nine families serve as basibionts for a wide range of phyla. The majority of records refer to Protista, followed by Nematoda and Crustacea. Only a few endobionts utilize the polyplacophoran’s valves as habitat, the overwhelming data refer to soft tissue infestations. Although the polyplacophoran anatomy of the involved taxa do not allow a prediction of endobiotic trends, the present data show a lack of basibionts from the more primitive polyplacophoran order Lepidopleurida. It is assumed that the scarcity of studied material of this primary deep-water group is more likely an explanation than the anatomical peculiarities of these polyplacophorans. The capability of polyplacophora as basibionts is definitively underrepresented and bears a wide source for future parasitological studies.

Helminth communities of two populations of Myotis chiloensis (Chiroptera: Vespertilionidae) from Argentinean Patagonia.

Most of the studies on chiropteran endoparasites in Argentina come from the Central and Northeast regions of the country, and there is only one parasitological study of bats from the Argentinean Patagonia. The aim of this study is to describe the helminth fauna of 42 Myotis chiloensis, comparing the composition and the structure of the endoparasite communities between two populations, inhabiting different environments in Andean humid forest and the ecotone between forest and Patagonian steppe. A total of 697 helminths were recovered from 33 bats: five species of trematodes, Ochoterenatrema sp., Paralecithodendrium sp., Parabascus limatulus, Parabascus sp., and Postorchigenes cf. joannae, two species of cestodes, Vampirolepis sp. 1 and Vampirolepis sp. 2, and three species of nematodes, Allintoshius baudi, Physaloptera sp., and Physocephalus sp. All the helminths, but Physocephalus sp., were recovered from the small and large intestine. This is the first survey of M. chiloensis’ helminth fauna. All the species, but A. baudi, represent new records of helminths in Patagonian bats. There were differences of parasite species richness between localities and both bat populations share almost half of the endoparasite species. Different preferences for intestinal regions were found for three species of trematodes in the bats from the site in the humid forest. Myotis chiloensis serves as both a definitive and intermediate host for endoparasites in the Patagonian ecosystem.

Parasitological and Pathological studies on Tissue parasites among slaughtered animals in Dakahlia province, Egypt

The present study was carried on 939 carcasses of slaughtered animals at Mansoura abattoir (387 cattle, 205 buffaloes and 347 sheep), of various ages, sex and breeds in order to investigate the incidence of grossly visible tissue parasites. Macroscopic Sarcocystis spp. cysts were recorded in 26.82% of examined buffalo carcasses. Hydatid cysts were recovered at overall incidence rate of 2.02%, where buffaloes showed higher infection (2.43%) than cattle (1.80%). Cysticercus bovis cysts were only recovered from heart of two cattle (0.51%), while no infection was detected in buffalo carcasses. Cysticercus tenuicollis cysts were found in cattle (0.25%). In sheep,Cysticercus tenuicollis cysts were recorded at high rate of 21.03% and Cysticercus ovis cysts were detected in 5.47% of examined sheep carcasses. The seasonal dynamics and anatomical distribution of the detected parasites were studied. Moreover, these parasites caused variable range of tissue lesions, from non-significant pathology as in macroscopic sarcocystosis to those caused extensive damage resulting in infiltrative, degenerative changes, necrosis and granuloma formation.

FERTILITY OF GOATS AFFECTED OF PARASITIC DISEASES

In modern conditions of management there is a need for systematical regulation of individual stages of the animal reproduction process in order to ensure the effective use of genetic resources of the breeding stock, planning of production processes and the timing of their implementation. One of the problems of the zootechnical and veterinary sciences are parasitic diseases and pathology parturition, which relates to the urgent issues of reducing the reproductive capacity of animals and inhibits the rapid development of livestock, in particular, goats breeding. In the case of a chronic course of parasitic diseases, animals do not enter hunting or note an inferior sexual cycle and, accordingly, farmers do not receive the applause and there are significant losses in milk productivity.
 The purpose of our research was to consider the main indicators characterizing reproducible ability of goats and the preservation of the offsprings in the presence of parasitic diseases. For this purpose we have applied parasitological and zootechnical methods of research. We examined 98 goats from 25 individual farms in the city Borispol. It was established that only 4,1% of our investigated 98 goats were free from parasites. 12.3% of goats were affected by one type of worms (Trichostrongylus axei), 26.5% of goats were affected by two types of worms (Trichostrongylus axei and Cooperia punctata), 21.4% – by three types of worms (Trichostrongylus axei, Cooperia punctata and Nematodirus spatiger, 20.4% – by four types of worms (Trichostrongylus axei, Cooperia punctata, Nematodirus spatiger, Ostertagia ostertagi), 10.2% – by five types of worms (Trichostrongylus axei, Cooperia punctata, Nematodirus spatiger, Ostertagia ostertagi Oesophagostomym radiatum) and 6.1% – by six types of worms (Trichostrongylus axei, Cooperia punctata, Nematodirus spatiger, Ostertagia ostertagi Oesophagostomium radiatum, Bunostomum phlebotomum). All revealed worms belonged to the Strongylata order and were pathogens gastrointestinal Strongylata infections in goats. In 25.5% of the examined animals, a significant defeat of Trichodectidae ectoparasites was observed. The analysis of the results showed the need for parasitological studies of animals kept in individual farms. The death of the goats predominantly accounts for the first 20 days of their post-embryonal life, which we observed in 77.8% of cases of death of the goats born from goats that revealed the presence of parasitic diseases. 6.4% of the goats from the coughing-affected parasites were unsatisfactory with a low clinical development status. In goats free from parasites, all born goats have a satisfactory clinical condition with high development potential.
 In the article we present the prospect of conducting further parasitological studies to ensure healthy clinical condition of animals, obtaining viable young animals and full realization of the productive potential of the animal.