Animal Parasitic Diseases Research Articles

Flavonoids and Related Compounds in Parasitic Disease Control

Flavonoids are natural plant compounds increasingly used in therapeutic applications. Their large spectrum of activities depends on their structures and cellular targets. Most recent research shows they are promising drugs for controlling human and animal parasitic diseases. Their multiple effects make it difficult to understand their modes of action, but some of them have been elucidated. This review also deals with their toxicity in mammals.

Genomics-Based Drug Design Targets the AT-Rich Malaria Parasite: Implications for Antiparasite Chemotherapy

Evaluation of: Woynarowski JM, Krugliak M, Ginsburg H: Pharmacogenomic analyses of targeting the AT-rich malaria parasite genome with AT-specific alkylating drugs. Mol. Biochem. Parasitol. 154(1), 70-81 (2007) [1] . The sequencing of the malaria genome sought to expose the parasite's ability to cause disease and identify new targets for antimalarial drugs and vaccines. In this study, the authors discovered how malaria genomic DNA, which is unusually rich in adenine and thymine nucleotides, is intrinsically a target for a selective class of compounds. AT-specific DNA-binding agents have previously been shown to have potent antimalarial activity in vitro. The authors used high-resolution bioinformatic tools to explore the genomic basis for this drug susceptibility, first at the level of individual DNA-binding sites, then expanding to the entire genomic context of each malaria chromosome. Their findings revealed a nonrandom distribution and organization of drug-binding sites that can be further exploited to target these AT sequences. Based on these findings, comparative bioinformatics analyses with other parasite genomes may lead to the identification of new target organisms for these AT-specific drugs and have wide implications for the treatment of human and animal parasitic diseases.

El control de enfermedades parasitarias por las vacunas como posible solución al problema de la farmacorresistencia

Antiparasitic drugs have been used successfully to control parasitic diseases in animals for many years, as they are safe, cheap and effective against a broad spectrum of parasites. One drawback of this success appears to be the emergence of drug resistance in many target parasites. Moreover, issues of residues in the food chain and environment have arisen, which threaten their sustained use. Control methods in which vaccines would have a central role provide attractive alternatives. However, while attenuated parasite vaccines have been successful, sub-unit vaccines are still rare. The advent of new techniques in molecular biology allows the elucidation of entire parasite genomes and the identification of individual genes. It is envisaged that a further understanding of parasite genes and the role of their products in parasite biology may lead to the identification of useful antigens, which could then be produced in recombinant systems. However, for this aim to be realised, continued investment in basic research on the complex interplay between parasite and host will be necessary.

Analysis of chicken embryonic gonad expressed sequenced tags

Animal GeneticsVolume 37, Issue 1 p. 85-86 Analysis of chicken embryonic gonad expressed sequenced tags J. H. Shin, J. H. Shin Avicore Biotechnology Institute Inc., Hanlim Human Tower no. 707, Geumjeong-Dong 1-40, Gunpo city, Gyeonggi-Do 435-050, KoreaSearch for more papers by this authorH. Kim, H. Kim Department of Food and Animal Biotechnology, Seoul National University, Seoul 151-921, KoreaSearch for more papers by this authorD. Lim, D. Lim Department of Food and Animal Biotechnology, Seoul National University, Seoul 151-921, KoreaSearch for more papers by this authorM. Jeon, M. Jeon Department of Food and Animal Biotechnology, Seoul National University, Seoul 151-921, KoreaSearch for more papers by this authorB. K. Han, B. K. Han Avicore Biotechnology Institute Inc., Hanlim Human Tower no. 707, Geumjeong-Dong 1-40, Gunpo city, Gyeonggi-Do 435-050, KoreaSearch for more papers by this authorT. S. Park, T. S. Park Department of Food and Animal Biotechnology, Seoul National University, Seoul 151-921, KoreaSearch for more papers by this authorJ. K. Kim, J. K. Kim Department of Microbiology, College of Natural Sciences, Changwon National University, Changwon 641-773, KoreaSearch for more papers by this authorH. S. Lillehoj, H. S. Lillehoj Animal Parasitic Diseases Laboratory, Animal and Natural Resource Institute, Building 1040, BARC-East, USDA-ARS, Beltsville, MD 20705, USASearch for more papers by this authorB. W. Cho, B. W. Cho Department of Animal Science, Miryang University, Miryang 627-702, KoreaSearch for more papers by this authorJ. Y. Han, J. Y. Han Department of Food and Animal Biotechnology, Seoul National University, Seoul 151-921, KoreaSearch for more papers by this author J. H. Shin, J. H. Shin Avicore Biotechnology Institute Inc., Hanlim Human Tower no. 707, Geumjeong-Dong 1-40, Gunpo city, Gyeonggi-Do 435-050, KoreaSearch for more papers by this authorH. Kim, H. Kim Department of Food and Animal Biotechnology, Seoul National University, Seoul 151-921, KoreaSearch for more papers by this authorD. Lim, D. Lim Department of Food and Animal Biotechnology, Seoul National University, Seoul 151-921, KoreaSearch for more papers by this authorM. Jeon, M. Jeon Department of Food and Animal Biotechnology, Seoul National University, Seoul 151-921, KoreaSearch for more papers by this authorB. K. Han, B. K. Han Avicore Biotechnology Institute Inc., Hanlim Human Tower no. 707, Geumjeong-Dong 1-40, Gunpo city, Gyeonggi-Do 435-050, KoreaSearch for more papers by this authorT. S. Park, T. S. Park Department of Food and Animal Biotechnology, Seoul National University, Seoul 151-921, KoreaSearch for more papers by this authorJ. K. Kim, J. K. Kim Department of Microbiology, College of Natural Sciences, Changwon National University, Changwon 641-773, KoreaSearch for more papers by this authorH. S. Lillehoj, H. S. Lillehoj Animal Parasitic Diseases Laboratory, Animal and Natural Resource Institute, Building 1040, BARC-East, USDA-ARS, Beltsville, MD 20705, USASearch for more papers by this authorB. W. Cho, B. W. Cho Department of Animal Science, Miryang University, Miryang 627-702, KoreaSearch for more papers by this authorJ. Y. Han, J. Y. Han Department of Food and Animal Biotechnology, Seoul National University, Seoul 151-921, KoreaSearch for more papers by this author First published: 26 January 2006 https://doi.org/10.1111/j.1365-2052.2006.01411.xCitations: 5 J. Y. Han (jaehan@snu.ac.kr) Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat No abstract is available for this article.Citing Literature Volume37, Issue1February 2006Pages 85-86 RelatedInformation

Herbal remedies in animal parasitic diseases in Nigeria: a review

This review of literature elucidates previous and current status of herbal remedies in animal parasitic diseases in Nigeria. It provides background information on the rationale behind ethnoveterinary research in general especially as it relates to the developing nations where cost of drugs majorly limit the full use of modern medicine. It presents in quantifiable terms the degree of efficacy of whole or plant parts and their extracts in percentages of efficacy. Dosages and concentrations were reported in certain instances especially in confirmatory research trials unlike in “surveys” where dosages were not recorded but presented only as “traditional practices among herdsmen” for which scientific validation is necessary. Also, comparative inferences were drawn between the efficacy of tested herb and its counterpart in modern medicine. This review concludes that ethnoveterinary medicine should form a part of modern day animal health delivery system. Key words: Herb, efficacy, ethno-veterinary, parasite.

Herbal remedies in animal parasitic diseases in Nigeria: a review

This review of literature elucidates previous and current status of herbal remedies in animal parasitic diseases in Nigeria. It provides background information on the rationale behind ethnoveterinary research in general especially as it relates to the developing nations where cost of drugs majorly limit the full use of modern medicine. It presents in quantifiable terms the degree of efficacy of whole or plant parts and their extracts in percentages of efficacy. Dosages and concentrations were reported in certain instances especially in confirmatory research trials unlike in “surveys” where dosages were not recorded but presented only as “traditional practices among herdsmen” for which scientific validation is necessary. Also, comparative inferences were drawn between the efficacy of tested herb and its counterpart in modern medicine. This review concludes that ethnoveterinary medicine should form a part of modern day animal health delivery system. African Journal of Biotechnology Vol. 4 (4), pp. 303-307, 2005

Agricultural policy and sustainable livestock development

Future agricultural and rural development is, to a large extent, influenced by the projected food needs of 2.5 billion people expected to swell the world population by 2020. This increase will require more food in general and, in view of recent experience in East Asia, more animal products. To achieve this increase will require judicious use of resources, and trade, especially in those countries where natural resources are insufficient to support food production. Achieving food sufficiency in a sustainable manner is a major challenge for farmers, agro-industries, researchers and governments. The latter play an important role as many of the farmer's choices are, to a large extent, directed by government or supra-government, often through macro- and micro-economic policy. In many countries the economic, environmental, trade and agricultural policies have not been conductive to an agricultural development that is risk-free with respect to the environment, animal welfare or public health. The recent decline of government support in agriculture forced farmers in Western countries to think about more risk adverse agricultural practices and more efficient production systems. On the other hand, many countries in Eastern Europe and the former Soviet Union, as well as other developing countries, are still going through a painful process of adjustment to new market conditions. International banks and development agencies have a mandate to help developing countries, but are somewhat restricted both by needing to work directly with governments and by their perceived dogmatic approach to development. Changing policies do, now and in the future, also affect the development of animal disease control programmes, including the control of parasitic diseases. On the one hand there is an increasing interest in risk-free control practices, and on the other hand a demand for greater regulatory control over the production process. As parasitic diseases of animals are closely linked to the environment (i.e. grazing and waste management) and public health (i.e. parasitic zoonoses), the new interest in sustainable agriculture provides a challenge for those concerned with the control and prevention of animal parasitism.

Weather-based computer experiments on parasites

Many parasitic diseases of man and animals are directly or indirectly influenced by weather, yet the relationship between prevalence and meteorological variables is poorly understood. Site-specific population models, constructed from experimental data, can be combined with computer simulation techniques to mimic the behaviour of parasites over a range of climatic conditions. This article describes the relationship between environmental factors and some parasitic diseases of animals. In particular, it presents some results of computer experiments with disease models to estimate the sensitivity of host-vector-parasite systems to environmental changes. The findings support the view that computer models, used in conjunction with geographical information systems (GIS) and environmental data bases, offer new prospects for the management of parasitic diseases.

History of veterinary parasitology in France

The history of veterinary parasitology in France can be divided into three parts. 1. (1) The early period of veterinary education, and development of sections on parasites and parasitic diseases, immediately following the creation of the veterinary colleges in France in 1762–1765 by Cl. Bourgelat until the beginning of the 19th century. This was the period of academics, naturalists and zoologists, with the exception of P. Chabert who, as early as 1782, directed attention to the harmful effects of parasites on animals and tried to control them. 2. (2) Identification and establishment of the field of veterinary parasitology and the development of specific research work, mostly in veterinary colleges, on the biology and systematic control of parasites. This period was dominated by the tremendous amount of work carried out by L.G. Neumann and A. Railliet in every topic of veterinary parasitology. 3. (3) The modern period of veterinary parasitology (before and after World War II). This period is characterized by the increasing development of the most sophisticated techniques in fundamental and applied research to provide efficient, cheap and practical means for the diagnosis and control of parasitic diseases in animals.

Standardized nomenclature of animal parasitic diseases (SNOAPAD)

An expert committee, appointed by the Executive Committee of the World Association for the Advancement of Veterinary Parasitology (W.A.A.V.P.), presents its proposal for uniform and proper terminology to denominate animal parasitic diseases or infections. In principle, the disease name is constructed solely by the suffix-osis, which is added to the stem of the name of the parasite taxon, formed from the nominative of the taxa. Standardized nomenclature of animal parasitic diseases (SNOAPAD) is meant as a guideline for general use, to improve the clarity of scienctific communication. It should be especially useful in promoting effective usage of computerized data retrieval services.

THE RELEVAI\CE OF PARASıTIC DISEASES OF ANnvlALS 1:\ TURKEY

Parasitic diseases of animals have a wide range of distribution in Turkey. A detailed information of the parasitic invasions and currently applied both preventive and therapeutie measures against the comman parasıtıc diseases, particularly those of in livestock are presented in this article. Turkey has a "ast potential for livestoek produetion. According to the latest statisties, the total number of livestoek is around 80 million. When poultry is included this number reaehes to 130 million. Despite of high number of animals in this eountry, prorl.uetion per animal is not satisfaetory. A number of factors do affeet the low lcvcl of produetion. One of the main factors is genctic infcriority of the animals. Howe\'er varioııs parasitic and infeetious di,seases also plaY,a major role in this respeet. To clarify the general distribution of the parasitic diseases, they may be classified under three headings as protozoan, helminthie inteetions and arthropod infestations.

ChemInform Abstract: IVERMECTIN, A NEW BROAD‐SPECTRUM ANTIPARASITIC AGENT

AbstractDurch Hydrierung von Avermectin B1 in Gegenwart des Katalysators (II) erhält man Ivermectin (I).

Ivermectin, a new broad-spectrum antiparasitic agent.

22,23-Dihydroavermectin B1, ivermectin, derived from avermectin B1 by selective hydrogenation using Wilkinson's homogenous catalyst [Ph3P)3RhCl], was shown to be a highly effective drug for the treatment of a wide variety of metazoan parasitic diseases in animals.

POISONING BY FOOD PROBABLY DUE TO CONTAMINATION WITH CERTAIN BACTERIA

Food poisoning, as it is understood today, is the result, directly or indirectly, of the contamination of food with certain bacterial organisms, and clinically it may be classified as an intoxication. However, it is recognized that, in the consumption of food contaminated with the paratyphoid group of bacteria, infections may occur. It is significant that none have been recorded in the data presented in this paper. The foregoing point of view regarding food poisoning is accepted or broadly interpreted throughout this paper, and no attempt will be made to discuss any other phase of food poisoning due to fungi, idiosyncrasies, the comparatively rare disease known as milk sickness, the dietary deficiency diseases or the obvious danger from the animal parasitic diseases. When the term general food poisoning is used, there is meant poisonings by food probably contaminated with the paratyphoid group or other organisms, and these, on account of the

The Distribution and Frequence of Animal Parasites and Parasitic Diseases in North American Fresh-Water Fish

The Distribution and Frequence of Animal Parasites and Parasitic Diseases in North American Fresh-Water Fish

Animal Parasitic Diseases of the Skin

Animal Parasitic Diseases of the Skin

Animal Parasitic Diseases of the Skin

Animal Parasitic Diseases of the Skin