ABSTRACT This study draws on the parasite stress theory of values to investigate the epidemiological origins of entrepreneurship. By analysing a country-level dataset spanning 14 years, this study finds that historical pathogen prevalence positively affects the rate of entrepreneurship, but negatively affects the proportions of three forms of high-quality entrepreneurship, i.e. technology entrepreneurship, growth-aspiring entrepreneurship, and export-oriented entrepreneurship. Collectivism is found to mediate the effects of historical pathogen prevalence on entrepreneurship and technology entrepreneurship. We find partial support that collectivism mediates the effects of historical pathogen prevalence on export-oriented entrepreneurship. This study contributes to a better understanding of the relationship between infectious diseases and entrepreneurship (and more broadly, economic activities), and demonstrates the enduring impact of infectious diseases through cultural factors.
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