Paraplegic Patients Research Articles

Perioperative Complications and In-Hospital Mortality in Paraplegic Radical Cystectomy Patients.

The aim of this study was to test for the association between paraplegia and perioperative complications as well as in-hospital mortality after radical cystectomy (RC) for non-metastatic bladder cancer. Perioperative complications and in-hospital mortality were tabulated in RC patients with or without paraplegia in the National Inpatient Sample (2000-2019). Of 25,527 RC patients, 185 (0.7%) were paraplegic. Paraplegic RC patients were younger (≤70years of age; 75 vs. 53%), more frequently female (28 vs. 19%), and more frequently harbored Charlson Comorbidity Index ≥3 (56 vs. 18%). Of paraplegic vs. non-paraplegic RC patients, 141 versus 15,112 (76 vs. 60%) experienced overall complications, 38 versus 2794 (21 vs. 11%) pulmonary complications, 36 versus 3525 (19 vs. 14%) genitourinary complications, 33 versus 3087 (18 vs. 12%) intraoperative complications, 21 versus 1035 (11 vs. 4%) infections, and 17 versus 1343 (9 vs. 5%) wound complications, while 62 versus 6267 (34 vs. 25%) received blood transfusions, 47 versus 3044 (25 vs. 12%) received critical care therapy (CCT), and intrahospital mortality was recorded in 13 versus 456 (7.0 vs. 1.8%) patients. In multivariable logistic regression models, paraplegic status independently predicted higher overall CCT use (odds ratio [OR] 2.1, p<0.001) as well as fourfold higher in-hospital mortality (p<0.001), higher infection rate (OR 2.5, p<0.001), higher blood transfusion rate (OR 1.45, p=0.009), and higher intraoperative (OR 1.56, p=0.02), wound (OR 1.89, p=0.01), and pulmonary (OR 1.72, p=0.004) complication rates. Paraplegic patients contemplating RC should be counseled about fourfold higher risk of in-hospital mortality and higher rates of other untoward effects.

Improving neurological deficits secondary to transverse myelitis using epidural spinal cord stimulation: illustrative cases.

Epidural spinal cord stimulation (eSCS) is canonically used for the treatment of intractable, chronic pain. Recent efforts have successfully utilized eSCS to improve neurological deficits in patients with spinal cord injury. However, there is a paucity of literature on the use of eSCS for demyelinating conditions, with no prior case reports examining eSCS among patients with transverse myelitis (TM). Two patients with TM underwent eSCS and experienced improvements in motor function and bladder symptoms. The first patient exhibited enhanced motor strength in both lower extremities and no longer experienced leg spasms, increasing exercise capacity and decreasing their fall risk. The patient had reduced incontinence pad usage due to a regained ability to sense bladder fullness. The second patient also experienced improved motor scores, leading to enhanced motor functionality and independence. Furthermore, the patient observed reductions in urinary tract infections post-eSCS. Neither patient reported substantial improvement in bowel function following stimulation. Improvements in motor functionality and bladder functioning are well-documented as factors that improve quality of life among paraplegic patients. Given the findings of the present case report, larger cohort studies examining the use of eSCS for demyelinating conditions, including TM, are warranted. https://thejns.org/doi/10.3171/CASE24152.

Paraplegic Patient with Metastatic Papillary Thyroid Cancer: A Multidisciplinary Approach to Radioactive Iodine Therapy Safety and Efficacy Strategy.

High-activity radioactive iodine (RAI) therapy for metastatic thyroid cancer (TC) requires isolation to minimize radiation exposure to third parties, thus posing challenges for patients needing hands-on care. There are limited data on the approach to high-activity RAI treatment in paraplegic patients. We report a state-of-the-art multidisciplinary approach to the management of bedbound patients, covering necessary radiation safety measures that lead to radiation exposure levels as low as reasonably achievable. Given the limited literature resources on standardized approaches, we provide a practical example of the safe and successful treatment of a woman with BRAFV600E-mutant tall-cell-variant papillary TC and pulmonary metastases, who underwent dabrafenib redifferentiation before RAI therapy. The patient was 69 y old and had become paraplegic because of a motor-vehicle accident. Since caring for a paraplegic patient with neurogenic bowel and bladder dysfunction poses radiation safety challenges, a multidisciplinary team comprising endocrinologists, nuclear medicine physicians, radiation safety specialists, and the nursing department developed a radiation mitigation strategy to ensure patient and staff safety during RAI therapy. The proposed standardized approach includes thorough monitoring of radiation levels in the workplace, providing additional protective equipment for workers who handle radioactive materials or are in direct patient contact, and implementing strict guidelines for safely disposing of radioactive waste such as urine collected in lead-lined containers. This approach requires enhanced training, role preparation, and practice; use of physical therapy equipment to increase the exposure distance; and estimation of the safe exposure time for caregivers based on dosimetry. The effective and safe treatment of metastatic TC in paraplegic patients can be successfully implemented with a comprehensive radiation mitigation strategy and thorough surveying of personnel for contamination.

Leech Therapy-aided recovery: A case study on accelerated healing of Decubitus ulcers in paraplegic patients

Leech Therapy-aided recovery: A case study on accelerated healing of Decubitus ulcers in paraplegic patients

Effect of magnetic therapy in bladder dysfunction and quality of life in paraplegic patients

BACKGROUND: Urinary dysfunction is linked to spinal cord injury (SCI). The quality of life (QoL) declines in both neurogenic bladder impairment and non-disordered patients. OBJECTIVE: To ascertain the effectiveness of pulsed magnetic therapy on urinary impairment and QoL in individuals with traumatic incomplete SCI. METHODS: This study included forty male paraplegic subjects with neurogenic detrusor overactivity (NDO) for more than one year following incomplete SCI between T6-T12. Their ages ranged from 20 to 35 and they engaged in therapy for three months. The subjects were divided into two groups of equal size. Individuals in Group I were managed via pulsed magnetic therapy once per week plus pelvic floor training three times a week. Individuals in Group II were managed with only three times a week for pelvic floor training. All patients were examined for bladder cystometric investigations, pelvic-floor electromyography (EMG), and SF-Qualiveen questionnaire. RESULTS: There was a noteworthy increment in individuals in Group I in volume of bladder at first desire to void and maximum cystometric capacity, detrusor pressure at Qmax, and maximum flow rate. There was a momentous increment in Group I in measures of evaluation of EMG biofeedback. There was a notable rise in Group I in SF-Qualiveen questionnaire. CONCLUSION: Magnetic stimulation should be favored as beneficial adjunct to traditional therapy in the management of bladder impairment and enhancing QoL in individuals with SCI.

Thoracic giant cell tumor after two total en bloc spondylectomies including one emergency surgery: A case report

BACKGROUND For patients with acute paraplegia caused by spinal giant cell tumor (GCT) who require emergency decompressive surgery, there is still a lack of relevant reports on surgical options. This study is the first to present the case of an acute paraplegic patient with a thoracic spinal GCT who underwent an emergency total en bloc spondylectomy (TES). Despite tumor recurrence, three-level TES was repeated after denosumab therapy. CASE SUMMARY A 27-year-old female patient who underwent single-level TES in an emergency presented with sudden severe back pain and acute paraplegia due to a thoracic spinal tumor. After emergency TES, the patient's spinal cord function recovered, and permanent paralysis was avoided. The postoperative histopathological examination revealed that the excised neoplasm was a rare GCT. Unfortunately, the tumor recurred 9 months after the first surgery. After 12 months of denosumab therapy, the tumor size was reduced, and tumor calcification. To prevent recurrent tumor progression and provide a possible cure, a three-level TES was performed again. The patient returned to an active lifestyle 1 month after the second surgery, and no recurrence of GCT was found at the last follow-up. CONCLUSION This patient with acute paraplegia underwent TES twice, including once in an emergency, and achieved good therapeutic results. TES in emergency surgery is feasible and safe when conditions permit; however, it may increase the risk of tumor recurrence.

Electrical stimulation of the cuneiform nucleus enhances the effects of rehabilitative training on locomotor recovery after incomplete spinal cord injury.

Most human spinal cord injuries are anatomically incomplete, leaving some fibers still connecting the brain with the sublesional spinal cord. Spared descending fibers of the brainstem motor control system can be activated by deep brain stimulation (DBS) of the cuneiform nucleus (CnF), a subnucleus of the mesencephalic locomotor region (MLR). The MLR is an evolutionarily highly conserved structure which initiates and controls locomotion in all vertebrates. Acute electrical stimulation experiments in female adult rats with incomplete spinal cord injury conducted in our lab showed that CnF-DBS was able to re-establish a high degree of locomotion five weeks after injury, even in animals with initially very severe functional deficits and white matter lesions up to 80-95%. Here, we analyzed whether CnF-DBS can be used to support medium-intensity locomotor training and long-term recovery in rats with large but incomplete spinal cord injuries. Rats underwent rehabilitative training sessions three times per week in an enriched environment, either with or without CnF-DBS supported hindlimb stepping. After 4 weeks, animals that trained under CnF-DBS showed a higher level of locomotor performance than rats that trained comparable distances under non-stimulated conditions. The MLR does not project to the spinal cord directly; one of its main output targets is the gigantocellular reticular nucleus in the medulla oblongata. Long-term electrical stimulation of spared reticulospinal fibers after incomplete spinal cord injury via the CnF could enhance reticulospinal anatomical rearrangement and in this way lead to persistent improvement of motor function. By analyzing the spared, BDA-labeled giganto-spinal fibers we found that their gray matter arborization density after discontinuation of CnF-DBS enhanced training was lower in the lumbar L2 and L5 spinal cord in stimulated as compared to unstimulated animals, suggesting improved pruning with stimulation-enhanced training. An on-going clinical study in chronic paraplegic patients investigates the effects of CnF-DBS on locomotor capacity.

Neuromodulation's Role in Functional Restoration in Paraplegic and Quadriplegic Patients.

Neuromodulation is an alternative, minimally invasive treatment option that, at times, is used as a last resort for chronic pain conditions that are often refractory to other treatment modalities. Moreover, it offers promising prospects for individuals grappling with the formidable challenges posed by paraplegia and quadriplegia resulting from spinal cord injuries. This review article provides a comprehensive assessment of current treatment modalities specifically tailored for paraplegic and quadriplegic patients. We aim to evaluate the existing surgical and non-surgical interventions while delving into the role of neuromodulation in the restoration of function for individuals afflicted with these debilitating conditions. Additionally, we review the efficacy, limitations, and comparative outcomes of diverse treatment strategies available for the management of paraplegia and quadriplegia. Emphasizing the critical need for effective interventions beyond the initial 24 h surgical window, we elucidate the challenges associated with conventional therapies and their limited success in achieving comprehensive functional restoration. Central to this review is an in-depth exploration of neuromodulation's transformative potential in ameliorating the deficits caused by spinal cord injuries. With a particular focus on spinal cord stimulation (SCS), we analyze and compare the outcomes of neuromodulation modalities and traditional treatment regimens, shedding light on the promising strides made in fostering sensory perception, motor function, and patient satisfaction.

Coordinated energy-efficient walking assistance for paraplegic patients by using the exoskeleton-walker system

Overground walking can be achieved for patients with gait impairments by using the lower limb exoskeleton robots. Since it is a challenge to keep balance for patients with insufficient upper body strength, a robotic walker is necessary to assist with the walking balance. However, since the walking pattern varies over time, controlling the robotic walker to follow the walking of the human-exoskeleton system in coordination is a critical issue. Inappropriate control strategy leads to the unnecessary energy cost of the human-exoskeleton-walker (HEW) system and also results in the bad coordination between the human-exoskeleton system and the robotic walker. In this paper, we proposed a Coordinated Energy-Efficient Control (CEEC) approach for the HEW system, which is based on the extremum seeking control algorithm and the coordinated motion planning strategy. First, the extremum seeking control algorithm is used to find the optimal supporting force of the support joint in real time to maximize the energy efficiency of the human-exoskeleton system. Second, the appropriate reference joint angles for wheels of the robotic walker can be generated by the coordinated motion planning strategy, causing the good coordination between the human-exoskeleton system and the robotic walker. The proposed approach has been tested on the HEW simulation model, and the experimental results indicate that the coordinated energy-efficient walking can be achieved with the proposed approach, which is increased by 60.16% compared to the conventional passive robotic walker.

Rotation Angle Control Strategy for the Hip Joint of an Exoskeleton Robot Assisted by Paraplegic Patients Considering Time-Varying Inertia

Rotation Angle Control Strategy for the Hip Joint of an Exoskeleton Robot Assisted by Paraplegic Patients Considering Time-Varying Inertia

CLINICAL AND FUNCTIONAL EVALUATION OF WRISTS AND HANDS OF SPINAL CORD INJURED PATIENTS.

The inability of the spinal cord to propagate sensory and motor stimuli as a result of the disruption of the nerve tracts is called spinal cord injury. This study analyzes clinically and radiologically the hands and wrists of spinal cord injured patients, evaluating their motor and sensitive functionality, in order to determine if these patients are more likely to develop degenerative alterations. 14 patients (8 paraplegics and 6 tetraplegics) were evaluated, undergoing anamnesis and clinical examination - a scale of muscular strength (MRC - Medical Research Council) and the amplitude measurement of the movement with a manual goniometer (ROM), were used for objective evaluation - and x-ray exams. The results were compared with pre-existing data from other studies. When asked, only one of the 14 observed patients complained about constant wrist pain, described as level 3 (weak to moderate), based on the visual analog scale (VAS). The motor evaluation, MRC and ROM divided the group of patients into two subgroups: paraplegic and tetraplegic patients. The x-ray analysis showed, based on Kellgren and Lawrence classification, that all exam images fit grades 1 or 2 of osteoarthritis and osteoarthrosis. In conclusion, spinal cord injured patients showed none or minimal clinical and radiological signs of osteoarthritis on hands or wrists. Overall, the hands and wrists of spinal cord-injured patients behave similarly to noninjured patients. Level of Evidence III; Retrospective Comparative Study.

A Parallel Compliant Leg for energy efficient walking of exoskeleton–walker systems

Lower limb exoskeletons have garnered significant attention for their effectiveness in gait training for paraplegic patients. For patients with insufficient trunk or upper limb strength to maintain balance, employing an unpowered robotic walker with an exoskeleton for gait training is an effective approach. The energy efficiency of the actuation system is a pivotal consideration in the design of the exoskeleton–walker system due to its significant influence on the system’s durability and service efficiency. The main contribution of this paper is the development of a Parallel Compliant Leg (PCL) for the exoskeleton–walker system. The PCL consists of both powered legs of the exoskeleton and a passive flexible mechanism within the walker. This integration allows for the storage and release of energy during cyclic walking, resulting in reduced system energy consumption. To enhance energy efficiency, the support force optimization of the flexible mechanism is established. Based on this optimization, a design scheme and parameter optimization for the flexible mechanism are proposed. The effectiveness of the proposed flexible mechanism is verified through simulations on a robot simulation platform. Experimental results demonstrate a remarkable 67.6% reduction in system energy consumption achieved by the optimized mechanism.

Robot assisted knee joint RoM exercise: A PID parallel compensator architecture through impedance estimation

Knee joint rehabilitation exercise refers to a therapeutic procedure of a patient having dysfunctions in certain abilities to move knee joint due to some medical conditions like trauma or paralysis. The exercise is basically a series of repeated assistive physical movements within the range of motion (RoM) of the joint. Reflex action of limbs during RoM exercise causes inappropriate balance of load which may cause secondary injuries, such as damages of muscle or tendon tissues. Establishing correlation between impedance data and limb motions is important to solve this problem. This paper aims to design and modeling of a robotic arm with an original approach in control strategy which is developed based on the correlation in between the joint-impedances and joint-motion characteristics during exercise. The knee joint impedances are estimated based on the internal feedback of the system dynamics, that lead to design the torque compensator to improve the overall control signals in real time. This paper also demonstrates the characteristics of various responses of the system during exercise with human subject. Results have reflected good performances with low position and velocity tracking errors, ±0.02∘ and 0.04rad.sec−1 during hold phase; and ±0.14∘ and 0.17rad.sec−1 during motion phse. Though, the limitation of the prototype is its current RoM (limited to 0∘–25∘), the system has potential in the application of RoM exercise for paraplegic or monoplegic patients.

A Case of Trueperella bernardiae Bacteremia due to a PICC-Associated Infection in a Paraplegic Patient

Trueperella bernardiae is a Gram-positive bacterium known to cause a wide variety of opportunistic infections in humans. We report a novel case of T. bernardiae bacteremia in a paraplegic patient due to a peripherally inserted central catheter- (PICC-) associated infection that was treated successfully with piperacillin/tazobactam.

Effect of Driving Simulator Training on Patients' Driving Performance and Self-Efficacy with Paraplegia due to Spinal Cord Injury

Objective: The purpose of this study was to investigate the effect of driving simulator training on the driving performance and self-efficacy of paraplegic patients with spinal cord injury.&#x0D; Method: Driving simulator training was provided to 12 participants with within subjects design, three sessions of basic driving, seven sessions of driving on the driving simulator. After training, performance time and operational performance scores, self-efficacy were analyzed.&#x0D; Results: This study found that the intervention by the driving simulator had statistically significant effects on driving time, performance error, ‘Sudden start’, ‘No neutral gear when stopping’, and ‘Speed violation’ and ‘Social self-efficacy’ of paraplegic spinal cord injury patients (p&lt;.05).&#x0D; Conclusion: Driving simulator training can be a strategy to improve driving performance and social self-efficacy of paraplegic patients with spinal cord injury. Also, patients need sufficient sessions more than 10 times of driving simulator training.

Trueperella bernardiae bacteremia in paraplegic patient with polymicrobial infection

Abstract: Trueperella bernardiae is an infrequently identified Gram-positive bacillus that has been isolated in various clinical infections. Here we report a case of T bernardiae infection in a paraplegic male and report antimicrobial susceptibilities.&#x0D; Keywords: Trueperella bernardiae, polymicrobial infection, antibiotic resistance

Outcome of Perforator Based VY Advancement Fasciocutaneous Flap for Sacral Pressure Sore Reconstruction

Background: Pressure sores are an ancient medical problem; were even found in autopsies of Egyptian mummies. Sacral pressure sore is more common among paraplegic and bedridden patients. The principle of treatment is excision of all dead &amp; devitalized tissue including scars, underlying bursa, and the involved bone, followed by durable coverage with Flap. Various flaps have been used to reconstruct the pressure sore, including Fasciocutaneous flaps, muscle flaps and free flaps. Among various local flaps, perforators based V-Y advancement fasciocutaneous flap is a reasonable and flexible option with good outcomes for sacral pressure sores reconstruction. Objectives: The purpose of this study was to evaluate the outcome of perforator based V-Y advancement fasciocutaneous flap for sacral pressure sores reconstruction concerning the sociodemographic characteristics of the patients, defect size, and outcome of surgery. Methods: This was a prospective observational study, conducted in the Burn &amp; Plastic Surgery department of Rangpur Medical College Hospital, Rangpur over a period of three years from August 2018 to September 2021 through purposive sampling. Patients of all ages and sexes having grade IV sacral pressure sores were included in this study. In all cases, perforator- based V-Y advancement fasciocutaneous flaps were used. Surgical technique, patient demographics, and outcome were evaluated. Results: A total of 30 patients were operated on. The age range was 18 – 65 years, among them 43.33% of patients were in the age range of 31 – 40 years. 80% of patients in this series were male. Traumatic paraplegia was the main cause of sacral pressure sore, and it was 70%. This study showed that in context to the length and breadth of the wound, a majority (30%) of the patients had a wound dimension of 71–90cm2. The smallest wound dimension was (5x6) = 30cm2 and largest wound dimension was (10x16) = 160cm2. Twenty-one sores that ranged from 6cm to 10cm were reconstructed with unilateral flaps and 09 sores that ranged from 11cm to 16cm were reconstructed with bilateral flaps. In this study, 06 (20%) patients had complications and all were managed conservatively. Three patients had infections and were treated according to the culture sensitivity report. Two patients had marginal flap necrosis at the vertical limb of Y which healed conservatively. One patient developed a seroma due to a blockage of the drain tube, which was resolved spontaneously. There was no flap loss in our study. The average follow-up period was one year. No recurrence of pressure sore during this period. Conclusion: The simplicity of the surgical procedure, minimum or no morbidity in the donor area, and satisfactory outcome in terms of recurrence make this a reasonable option for the reconstruction of the sacral pressure sore. J Rang Med Col. September 2023; Vol. 8, No. 2: 20-24

SAT559 Challenges Involved in Managing a Paraplegic Patient with Metastatic Papillary Thyroid Cancer Requiring Radioactive Iodine Therapy

Abstract Disclosure: G. Al-Naqeeb: None. E. Munger: None. P. Veeraraghavan: None. C. Cochran: None. P. Bernaldez: None. P. Wong: None. N. Devaraj: None. T. Fisher: None. K. Lee: None. O. Owoade: None. I. Jones: None. S. Gubbi: None. J. Klubo-Gwiezdzinska: None. Background: High radioactive iodine (RAI) therapy doses utilized for treating thyroid cancer patients require a 24-48-hour radiation isolation period until the total effective dose equivalent exposure (TEDE) to the general population does not exceed 5mSv. We present a unique scenario of a paraplegic patient with metastatic papillary thyroid cancer (PTC) requiring RAI therapy and the radiation precaution strategies implemented by our team to reduce radiation exposure risk to the medical staff.A 69-year-old female with RAI-refractory tall cell-variant PTC (pT4aN1bM1; BRAF V600E pathogenic variant) with pulmonary metastases, paraplegia due to a motor vehicle accident with neurogenic bowel and bladder, was referred to our center for management of PTC. Laboratory data revealed a serum thyroglobulin of 2313 ng/mL (normal=1.6-59.9), and anatomical imaging showed numerous pulmonary nodules that had increased in size and number compared to prior imaging from 6 months ago. Due to disease progression, re-differentiation therapy with dabrafenib was initiated. After 3-months of dabrafenib therapy, a diagnostic thyroid hormone withdrawal-aided 131I scan with dosimetry revealed a significant re-induction of RAI uptake in pulmonary lesions and it was determined that therapy with an RAI dose of 200 mCi would not exceed a safe radiation exposure to the bone marrow of 200 rads. A multi-step mitigation strategy was developed based on a multidisciplinary team meeting and appropriate mock sessions. Stay times were estimated for individuals based on historical TEDE following the care of non-paralyzed patients receiving similarly prescribed activity. To minimize exposure to nursing staff, the patient’s Foley catheter was shielded with lead lining and bowels were emptied the night before RAI with a laxative. For each entry, posted safety sheets were updated with one-foot and one-meter isodose lines and on-contact exposure rates. Two nurses and one radiation safety staff member donned full personal protective equipment (PPE; full body suit, double gloves, booties, face covering) in the staging area and entered via lane one. While nursing provided direct care needs, radiation safety staff emptied the shielded catheter, organized clutter and packaged radioactive waste containers. Upon completion of duties, staff exited via lane two, removed PPE, and performed a full personnel contamination survey in the staging area. The patient successfully underwent RAI therapy with 200 mCi. Six months later the serum thyroglobulin had reduced to 48.4ng/ml with a substantial reduction in pulmonary metastatic tumor burden on imaging studies. Conclusion: Post-RAI therapy care of paralyzed patients during radiation isolation poses a unique challenge to medical staff warranting modifications in routine care practices, which can be achieved safely through optimal planning and enhanced training. Presentation Date: Saturday, June 17, 2023

Nursing Experience of Traditional Chinese Medicine Comprehensive Nursing Combined with Fasting Therapy in Paraplegic Patients

This study aims to explore the application and experience of traditional Chinese medicine comprehensive nursing combined with fasting therapy in the care of paraplegic patients. By reviewing the clinical situation of paraplegic patients who underwent traditional Chinese medicine fasting therapy from May 2022 to July 2023, and observing the changes in their quality of life through combined traditional Chinese medicine comprehensive nursing. The results show that the combination of traditional Chinese medicine comprehensive nursing and fasting therapy has a positive effect on the care of paraplegic patients.

Cases of spinal cord injury: correlation among resilience, social support and psychological well-being

Background: Spinal injuries are highly prevalent and are a major cause of disability. Studying resilience, perceived social support, and psychological well-being in persons with spinal cord injury is important for better-managing patients with spinal cord injuries. Objectives: To analyze the correlation among resilience, perceived social support, and psychological well-being in persons with spinal cord injury. Methods: This cross-sectional correlational study was conducted at Riphah International University, Lahore Pakistan from September 2019 to February 2020. The study utilized a sample of 100 patients with spinal cord injury using purposive sampling. The sample included paraplegic patients 6 months following SCI, of both genders above 18 years of age who were active wheelchair users. A demographic sheet, scale of psychological well-being, resilience scale, and multi-dimensional scale of perceived social support (MSPSS) were used for data collection. SPSS Version 22 was utilized for data analysis &amp; correlation was analyzed using bivariate statistics with p&lt; 0.05 was considered statistically significant. Results: The study revealed a positive correlation (γ=0.57, p&lt;0.001) between Resilience with Perceived Social Support; Resilience and Psychological well-being (γ=0.55, p&lt;0.001); and Perceived Social Support and Psychological Well-being (γ =0.57, p&lt;0.001). Conclusion: There is a positive relationship between resilience perceived social support and psychological well-being. Keywords: perceived social support; psychological wellbeing; resilience; spinal cord injury