Neurons In Parabrachial Nucleus Research Articles

Parabrachial nucleus neurons projecting to the lower brain stem and the spinal cord. A study in the cat by the Fink-Heimer and the horseradish peroxidase methods

Direct projections from the parabrachial nucleus (PBN) to the lower brain stem and the spinal cord were examined in the cat by the Fink-Heimer and the horseradish peroxidase (HRP) methods. After placing lesions in the PBN, many fine degenerated fibers were seen contralaterally in the ventromedial portions of the caudal pontine reticular formation, and ipsilaterally in the lateral portions of the facial nucleus, the regions around the hypoglossal nucleus, and the regions around the ambiguus nucleus; some degenerated fibers were traced ipsilaterally down to the spinal cord. Subsequently, HRP injections were attempted into these regions where many fine degenerated fibers were observed. In cats injected with HRP into the lateral portions of the facial nucleus, the regions around the hypoglossal nucleus, the regions around the ambiguus nucleus, or the first cervical cord segment, many HRP-labeled neurons were seen in the ventral portions of the PBN. The mean of the average soma diameters of the PBN neurons labeled with HRP injected into the regions around the hypoglossal nucleus or the first cervical cord segment was significantly larger than that of the PBN neurons labeled with HRP injected into the lateral portions of the facial nucleus or the regions around the ambiguus nucleus.

Localization of parabrachial nucleus neurons projecting to the thalamus or the amygdala in the cat using horseradish peroxidase

Topographical localization of parabrachial nucleus (PBN) neurons projecting directly to the thalamus or the amygdala was examined in the cat by the horseradish peroxidase (HRP) method. After HRP injection in the central nucleus of the amygdala, PBN neurons labeled with the enzyme were seen ipsilaterally in the ventral portion of the lateral PBN as well as in the medial PBN. When the HRP injections were centered on the parvocellular portion of the posteromedial ventral nucleus of the thalamus (VPMpc), HRP-labeled neurons were observed ipsilaterally in the dorsal portion of the lateral PBN as well as in the medial PBN. Within the medial PBN, the distribution of neurons projecting to the amygdala overlapped that of neurons projecting to VPMpc; the cell bodies of the former neurons, however, tended to be more elongated than the latter, and the mean of the average soma diameters of the former was significantly larger than the latter. On the other hand, in the lateral PBN no significant differences were noted between the means of the average soma diameters of neurons projecting to VPMpc and those projecting to the amygdala. The PBN neurons in the cat were presumed to transmit gustatory and general visceral information ipsilaterally to the thalamic taste region and the limbic areas in the basal forebrain.

Synaptic processing of taste-quality information in the nucleus tractus solitarius of the rate.

Synaptic processing of taste-quality information in the nucleus tractus solitarius of the rate.

Copper sulphate emesis; a study of afferent pathways from the gastrointestinal tract.

ArticleCopper Sulphate Emesis: A Study of Afferent Pathways from the Gastrointestinal TractS. C. Wang, and Herbert L. BorisonS. C. WangFrom the Department of Physiology, College of Physicians and Surgeons Columbia University, New York City, and Herbert L. BorisonFrom the Department of Physiology, College of Physicians and Surgeons Columbia University, New York CityPublished Online:31 Jan 1951https://doi.org/10.1152/ajplegacy.1951.164.2.520MoreSectionsPDF (1 MB)Download PDF ToolsExport citationAdd to favoritesGet permissionsTrack citations ShareShare onFacebookTwitterLinkedInWeChat Previous Back to Top Next Download PDF FiguresReferencesRelatedInformation Cited ByDelineation of vagal emetic pathways: intragastric copper sulfate-induced emesis and viral tract tracing in musk shrewsCharles C. Horn, Kelly Meyers, Audrey Lim, Matthew Dye, Diana Pak, Linda Rinaman, and Bill J. Yates1 March 2014 | American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, Vol. 306, No. 5Integrative responses of neurons in parabrachial nuclei to a nauseogenic gastrointestinal stimulus and vestibular stimulation in vertical planesTakeshi Suzuki, Yoichiro Sugiyama, and Bill J. Yates15 April 2012 | American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, Vol. 302, No. 8Integrative responses of neurons in nucleus tractus solitarius to visceral afferent stimulation and vestibular stimulation in vertical planesYoichiro Sugiyama, Takeshi Suzuki, Vincent J. DeStefino, and Bill J. Yates1 November 2011 | American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, Vol. 301, No. 5Gastrointestinal motor and myoelectric correlates of motion sicknessIvan M. Lang, S. K. Sarna, and R. Shaker1 September 1999 | American Journal of Physiology-Gastrointestinal and Liver Physiology, Vol. 277, No. 3 More from this issue > Volume 164Issue 2January 1951Pages 520-526 Copyright & PermissionsCopyright © 1951 by American Physiological Societyhttps://doi.org/10.1152/ajplegacy.1951.164.2.520PubMed14810961History Received 2 August 1950 Published online 31 January 1951 Published in print 31 January 1951 Metrics