Besides the performances of handling, stability, ride comfort, power and fuel economy, the sound pressure levels in the automobile passenger compartments heavily influence the customer’s purchasing decision. The interior acoustics of automobile passenger compartment was analyzed in this paper. The frequency response analysis was performed on the vehicle body due to road roughness. The frequency response of vehicle body’s output spectrum, nodes’ velocity is used as the boundary condition of the acoustic cavity. With boundary element method and acoustic transfer vector method, the panel acoustic contribution was analyzed. By modifying the stiffness, damping or mass of the corresponding panel, the acoustic pressure levels at the driver’s and passenger’s ear were decreased.