AbstractContemporary kinematic characteristics of the Pamir plateau are characterized by (a) significant NS‐shortening across the northern front, (b) EW‐extension within the Pamir and (c) gravitationally driven westward mass‐outflux of the western Pamir into the Tajik basin. The 2015 Mw 7.2 Sarez and 2023 Mw 6.8 Murghab strike‐slip earthquakes highlight the crucial role of shear deformation in the Pamir's interior, but the detailed secular kinematics of the remote Plateau are still elusive. Here, we employ elastic block models to fit GNSS velocities compiled from our own reprocessed velocity solution and from previous studies to determine slip rates along major active faults within and bounding the Pamir plateau. Our favored model separates the Pamir's interior into three micro‐blocks along the NNE‐trending sinistral Sarez‐Karakul fault system and the SSE‐trending Kongur Shan extensional system. The model confirms significant crustal shortening along the Pamir's northern boundary and strike‐slip motion along its western boundary, namely the Pamir thrust system and the Darvaz fault, respectively. In contrast, strike‐slip motion on the eastern boundary is minor. In the interior of the Plateau, we find an upper limit of sinistral shear of 8.8 ± 0.3–9.5 ± 0.2 mm/yr along the Sarez‐Karakul fault system and dextral shear of 6.3 ± 0.3 mm/yr along the WNW‐trending Muji fault. Our model also confirms recent observations of an active, SW‐continuation of the Sarez‐Karakul fault system. In the eastern Pamir, crustal extension mainly occurs across the northern segment of the Kongur Shan extensional system. The recent large strike‐slip earthquakes on the Pamir plateau suggest that shear motion on the plateau is accommodated on a much wider range than only by the Sarez‐Karakul fault system.