A novel palladium-catalyzed domino reaction of 2-methylindoles with 2-iodobenzyl bromide in the system Pd(OAc) 2 /Xantphos/ t -BuOK/PhMe leading to indole-fused tricyclo[7,3,1,0 2,7 ]trideca-2(7),3,5-triene ring system is presented. Pd-catalyzed reaction of 2-methylindole with 5-bromo-6-bromomethylbenzo[1,3]dioxole afforded 3,3-bis(6-bromobenzo[1,3]dioxol-5-ylmethyl)-2-methyl-3 H -indole. How to Cite Abele, E.; Belyakov, S.; Beresneva, T.; Golomba, L.; Abele, R. Chem. Heterocycl. Compd. 2016 , 52 , 140. [ Khim. Geterotsikl. Soedin. 2016 , 52 , 140.] For this article in the English edition see DOI 10.1007/s10593-016-1846-2