Geochemical evidence suggests the iron- and silica-rich precipitates that compose large Neoarchean and Paleoproterozoic iron formations formed along a chemocline between iron-rich deep water and iron-poor surface water. Sedimento-logical evidence indicates many large iron formations accumulated in marine shelf environments during major transgressions. We suggest this occurred because the chemocline could only impinge on continental shelves during times of sea-level rise or highstand. On the other hand, the stratigraphic record indicates that deposition of iron formations ceased during regressions in some basins and transgressions in others. To explain this, we propose that iron concentrations in the Precambrian ocean were greatest at mid-water depths in a zone on the order of 100 m thick. Radiometric age dates from the Hamersley Basin of Western Australia suggest major iron-formation deposition had a periodicity of ca. 20 to 125 m.y., close to second-order cycles in Phanerozoic sea level driven by long-te...