This study examines the mineral and whole-rock compositions and paleomagnetic dating of lamprophyres from the West Coast Alkaline Complex (WCAC) within the Deccan Large Igneous Province. We aim to elucidate their connection with the Réunion plume, Deccan tholeiite magmatism, the onset of rifting and separation of Seychelles, and the role of lithospheric thinning.WCAC lamprophyres contain olivine and phlogopite phenocrysts/macrocrysts set in a groundmass of carbonate, clinopyroxene, nepheline, spinel, and melilite. They are characterized by Ti-Al phlogopite and Al-enriched spinels with high Fe2+/(Fe + Mg) ratios. They are undersaturated in silica and rich in MgO, TiO2, and LREEs, resembling the global ultramafic lamprophyres (UMLs).They originated from an enriched garnet lherzolite mantle, metasomatized by silicate and carbonate veins. Trace-element modeling suggests the derivation of melt by ∼1% partial melting of phlogopite-bearing garnet lherzolite mantle, corresponding to moderate pressure depths (3–4 GPa) and lithospheric mantle thickness of 90–100 km. Paleomagnetic investigations corroborate their intrusions, primarily during chron C29n, approximately at 65 Ma, which coincided with amplified plate velocities in the Indian Ocean.Seismic tomography indicates a current lithospheric thickness of about 50 km under the western Indian margin, suggesting a lithospheric delamination of about 40–50 km following the intrusion of lamprophyres at ca. 65 Ma. The initiation of passive rifts in the region, culminating in the separation of the Indian subcontinent and the Seychelles, prompted the UML magmatism. Lithospheric thinning continues along with continental rifting in response to greater plate-tectonic stresses within regions of persistent lithospheric weakness.